[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"immediate-dental-implant-loading\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:immediate-dental-implant-loading":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100638608","influence-of-the-primary-stability-and-temporary-prosthetics-100638608",false,"NCT07585539","Influence of the Primary Stability and Temporary Prosthetics","Influence of the Primary Stability and Temporary Prosthetics of a Placed Dental Implant on Implant Osseointegration and Further Function When Performing Immediate Implantation in the Posterior Tooth Regions.","Inclusion Criteria:\n\n* ≥ 18 years old.\n* healthy patients without medical contraindications for dental implantation surgery.\n* removable and non-molar teeth indicated for extraction in both jaws\n* healthy soft tissues (bleeding on probing \\\u003C 20%, plaque index \\\u003C 25%);\n* intact alveolar bone walls post-extraction\n* signed informed consent form and permission to use the obtained data for research purposes.\n\nExclusion Criteria:\n\n* Smokers (≥ 10 cigarettes per day);\n* history of uncontrolled periodontitis;\n* uncontrolled diabetes\u002Falcoholism;\n* use of drugs that may affect healing;\n* persons who, due to health status, cannot be considered capable of reasonably assessing their interests;","ALL","18 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to to determine how different primary implant stability and loading management affect implant osseointegration and further function after one year. The main questions it aims to answer are: is primary stability of inserted implant needed for implant integration? Does primary stability and restoration mode of the implant influence marginal bone stability of that implant? Researchers will compare crestal bone levels and primary stability of the implant after insertion in 3 groups. Subjects will be assigned to groups, acoording to primary stability developed during insertion of the implant. Study groups - (1) If stability is low (5-10 N\u002Fcm), Megagen BlueDiamond implants will be inserted, and a temporary prosthesis will not be placed; the implant will be sutured; (2) If stability is moderate (15-35 N\u002Fcm), Megagen BlueDiamond implants will be inserted, and a custom plastic gingiva-forming healing abutment will be placed; (3) If stability is high (40 N\u002Fcm and higher), Megagen BlueDiamond implants will be inserted, and a temporary plastic crown will be placed. Primary outcome of the study will be implant integration, secondary ourtcomes - implant insertion depth during insertion and after osseointegration, marginal bone stability after prosthesis delivery and after one year, determination of the PES (pink esthetic score) index after prosthesis delivery and after 1 year, determination of the ISQ value after implant insertion and after osseointegration, changes in gingival volume around the implants after 1 year, determination of the Plaque Index (PI) after prosthesis delivery and after 1 year, determination of the Probing Pocket Depth (PPD) after prosthesis delivery and after 1 year, determination of the Bleeding on Probing (BOP) index after prosthesis delivery and after 1 year.",[26,27,28],"Immediate Dental Implant Placement","Immediate Dental Implant Loading","Marginal Bone Levels",[30],"Dental implant","NOT_YET_RECRUITING","2026-05-09",{"date":34,"type":35},"2026-05-13","ACTUAL",{"date":37,"type":20},"2026-05-07",{"date":39,"type":20},"2028-01-05",{"name":41,"class":42},"Tomas Linkevicius","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100631275","immediate-restoration-of-a-new-implant-with-high-primary-stability-100631275","NCT07498556","Immediate Restoration of a New Implant With High Primary Stability","Immediate Restoration of a New Implant With High Primary Stability: A 1-year Follow-up - Clinical Study","CT","Inclusion Criteria:\n\n* Men and women between 18 and 70 years of age.\n* Ability to read, understand, and sign the informed consent form.\n* Need for placement of one or more implants for fixed prosthetic rehabilitation in either arch.\n* Insertion torque ≥ 35 Ncm (lower values will be excluded from the study).\n* Adequate bone dimensions to receive an implant with diameter ≥ 3.75 mm and length ≥ 10 mm.\n* Bone type I to III at the insertion site.\n* Good oral hygiene: FMBS and FMPS ≤ 25%.\n* Systemic status classified as ASA I or II.\n\nExclusion Criteria:\n\n* Inability to attend follow-up appointments.\n* Systemic contraindications to oral surgery (ASA III or IV).\n* Pregnancy or breastfeeding.\n* Chronic use of corticosteroids, bisphosphonates, or RANKL inhibitors within the last year.\n* Alcohol or drug abuse.\n* Heavy smoking (≥ 10 cigarettes\u002Fday).\n* Previous radiotherapy in the cervicofacial region.\n* Untreated active periodontal disease.\n* Absence of antagonist teeth.\n* Local pathology at the planned implant site.\n* Uncontrolled diabetes mellitus (HbA1c \\> 7%).\n* Bone type IV at the surgical site.","70 Years",{"count":53,"type":20},50,[23],"The main objective of this scientific study is to evaluate the short-term (1-year) survival and success rates of dental implants restored immediately compared to implants restored after a three-month healing period.\n\nThe total duration of the study is 12 months following implant placement, during which clinical and radiographic evaluations will be carried out at different follow-up time points.",[57,27],"Dental Implants",[59,60,61,62,63,64],"dental implants","Immediate loading","Delayed loading","Implant survival rate","Marginal bone loss","Esthetic outcome evaluation","2026-04-28",{"date":67,"type":35},"2026-05-05",{"date":69,"type":20},"2026-07-01",{"date":71,"type":20},"2027-12-30",{"name":73,"class":42},"Universidade do Porto",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":74},"100621746","vertical-root-extraction-for-immediate-implant-100621746","NCT07374627","Vertical Root Extraction for Immediate Implant","Vertical Root Extraction for Immediate Implant Placement : A Prospective Clinical And Radiographic Single Arm Study.","Benex","Inclusion Criteria:\n\n\\- dults aged 18 to 55 years. Classified as ASA I-II (healthy or mild systemic condition, fit for surgery). The presence of a single hopeless maxillary anterior tooth (incisor or canine) indicated for extraction.\n\nAdequate palatal and apical bone volume to achieve primary stability for immediate implant placement.\n\nPatients are able and willing to provide informed consent and comply with study visits.\n\nExclusion Criteria:\n\nSmokers consuming more than 10 cigarettes per day. Pregnant or lactating women. Patients with systemic contraindications to surgery (e.g., chemotherapy, radiotherapy, bisphosphonate therapy).\n\nPatients with untreated periodontal disease. Presence of active local infection at the surgical site.\n\n\\-",true,"80 Years",{"count":86,"type":20},14,[23],"Immediate implant placement in the esthetic zone has become a preferred treatment modality due to its potential to shorten treatment duration, reduce surgical interventions, and preserve the natural contour of peri-implant tissues (Chen \\& Buser, 2009; Lang et al., 2012). Despite these advantages, the technique remains surgically demanding, especially in the anterior maxilla, where the labial plate is often thin and highly susceptible to post-extraction resorption (Spray et al., 2000; Chappuis et al., 2017).\n\nThe greatest dimensional changes in alveolar ridge volume occur within the first 8-12 weeks after tooth extraction, with reductions in both height and width of the buccal bone crest (Araújo \\& Lindhe, 2005; Tan et al., 2012). This remodeling compromises mucogingival architecture, often leading to mid-facial soft tissue recession and esthetic failures. Conventional extraction methods, which apply rotational or lateral forces using elevators and forceps, risk fracturing the socket walls and accelerating bone loss (Araujo \\& Lindhe, 2009; Oghli \\& Steveling, 2010).\n\nThe introduction of atraumatic extraction systems aimed to address this challenge. The Benex vertical extraction system operates by inserting a screw into the root canal and applying controlled vertical traction. This approach minimizes lateral stress on socket walls, theoretically preserving the thin labial plate, which is critical for esthetic success (Muska et al., 2013; Canellas et al., 2021). Vertical traction avoids socket expansion and microfractures, enabling safer immediate implant placement in compromised situations.\n\nCase reports and retrospective series have demonstrated encouraging clinical results with Benex, including intact labial plates on CBCT, high implant survival, and favorable Pink Esthetic Scores (Fürhauser et al., 2005; Canellas et al., 2021). Patients also report reduced discomfort and trauma perception, suggesting potential psychosocial benefits. However, most of the current evidence is based on small-scale case series (Blus \\& Szmukler-Moncler, 2010; Singla \\& Sharma, 2020), and randomized controlled trials comparing Benex-assisted extraction with conventional atraumatic extraction are lacking.\n\nA robust RCT evaluating both objective esthetic outcomes (Midfacial mucosal recession, PES, CBCT bone preservation) and subjective patient-reported outcomes (PROMs) is therefore essential to validate the clinical value of the Benex system in the esthetic zone.",[90,27],"Implant Placement in Maxillary Esthetic Zone",[92,93],"Dental Implant","root extraction","2026-01-21",{"date":96,"type":35},"2026-01-29",{"date":98,"type":20},"2026-02-01",{"date":100,"type":20},"2026-04-30",{"name":102,"class":42},"Cairo University"]