[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"immediate-implant\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:immediate-implant":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,71,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100628238","artificial-intelligence-guided-versus-manual-cbct-planning-for-immediate-implant-placement-100628238",false,"NCT07459036","Artificial Intelligence-Guided Versus Manual CBCT Planning for Immediate Implant Placement","Artificial Intelligence-Guided Versus Manual CBCT Planning for Immediate Implant Placement in Molar Extraction Sites: A Randomized Controlled Trial","AI","Inclusion Criteria:\n\n* Adults≥18 years are able to provide informed consent. Indicated for the extraction of a molar tooth (maxillary or mandibular) with planned implant-supported rehabilitation.\n* Candidate for immediate implant placement attempt based on preoperative clinical evaluation and CBCT availability.\n* Preoperative CBCT will be acquired using the study imaging protocol within a defined window (e.g., ≤4 weeks before surgery).\n* Adequate oral hygiene and periodontal condition compatible with implant surgery (e.g., treated\u002Fstable periodontal status per clinician judgement).\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding (due to imaging\u002Fsurgical considerations).\n* Uncontrolled systemic disease or medical contraindication to oral surgery\u002Fimplant placement (e.g., uncontrolled diabetes, immunosuppression as judged by clinician).\n* History of head and neck radiotherapy in the implant region. Use of medications associated with compromised bone healing where immediate implant placement is not advised (e.g., high-dose antiresorptives\u002FIV bisphosphonates; you can specify per your clinic policy).\n* Acute uncontrolled infection at the site requiring staged management (e.g., spreading cellulitis\u002Fabscess) or other condition precluding immediate placement per surgeon judgement.\n* Need for simultaneous major augmentation that precludes immediate implant placement (e.g., extensive ridge reconstruction planned at the same surgery rather than socket-level grafting).\n* Inadequate CBCT quality for segmentation\u002Fmeasurement (motion artifacts, incomplete field of view, or metal artifact obscuring the septum).",true,"ALL","18 Years","99 Years",{"count":22,"type":23},80,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study evaluates whether artificial intelligence (AI)-based analysis of cone-beam computed tomography (CBCT) scans can support clinical decision-making for immediate dental implant placement in molar extraction sites.\n\nWhen a molar tooth is removed, placing a dental implant immediately may reduce treatment time and preserve surrounding bone. However, immediate implant placement is not always possible and depends on the anatomy of the extraction socket, particularly the interradicular septum (the bone between the roots). CBCT imaging is routinely used to assess this anatomy before surgery. Traditionally, radiologists manually evaluate these scans. Recently, AI-based tools have been developed to automatically analyze CBCT images.\n\nIn this randomized controlled trial, patients requiring molar extraction and potential immediate implant placement will be assigned to one of two planning approaches: AI-guided CBCT assessment or conventional manual CBCT assessment. The operating surgeon will use the assigned planning report to guide treatment decisions.\n\nThe primary outcome of the study is the feasibility of immediate implant placement, defined as successful implant placement with achievement of primary stability during surgery. Secondary outcomes include surgical time, need for changes to the treatment plan, and implant stability measurements.\n\nThe goal of this study is to determine whether AI-assisted CBCT analysis performs similarly to, or improves upon, conventional manual radiologic assessment in supporting safe and effective immediate implant placement.",[29,30,31],"Dental Implant","Immediate Implant","Guided Bone Regeneration","NOT_YET_RECRUITING","2026-03-06",{"date":35,"type":36},"2026-03-09","ACTUAL",{"date":38,"type":23},"2026-03-03",{"date":40,"type":23},"2026-05-02",{"name":42,"class":43},"Shalash Dental education","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":24,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":44},"100565482","buccal-plate-augmentation-using-sticky-bone-with-simultaneous-immediate-implant-placement-100565482","NCT06642753","Buccal Plate Augmentation Using Sticky Bone With Simultaneous Immediate Implant Placement","Buccal Plate Augmentation Using Sticky Bone Versus Usage of Sticky Bone as a Jumping Gap Filling Material With Simultaneous Immediate Implant Placement in the Maxillary Esthetic Zone :A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Presence of a non-restorable maxillary tooth in the esthetic zone including maxillary anteriors and premolars indicated for extraction.\n* An intact buccal plate of bone after extraction.\n* Full-mouth plaque and bleeding score not exceeding 20%.\n* Patients showing motivation to comply with post-operative care instructions and follow- up appointments.\n\nExclusion Criteria:\n\n* Periapical infection involving the tooth to be extracted.\n* Periodontal disease\n* Systemic health conditions that contraindicate or affect healing of implant surgery (Diabetes Mellitus, Leukemia)\n* Pregnant and nursing females.\n* Smokers",{"count":53,"type":23},20,[26],"the aim of this study is to clinically assess pink esthetic score following Buccal Plate Augmentation using Sticky Bone versus usage of Sticky Bone as a jumping gap filling material with simultaneous immediate implant placement in the maxillary esthetic zone",[30],[58,59,60],"buccal plate preservation","sticky bone","PRF","RECRUITING","2024-10-21",{"date":64,"type":36},"2024-10-23",{"date":66,"type":36},"2024-06-01",{"date":68,"type":23},"2025-05",{"name":70,"class":43},"Cairo University",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":18,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":24,"phases":80,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":44},"100561348","phase-2-xengenic-cortical-membranes-versus-connective-tissue-graft-with-coronally-advanced-flap-for-the-treatment-of-peri-implant-soft-tissue-dehiscences-a-randomized-controlled-clinical-trial-100561348","NCT06588998","Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults (20-50) years old. •peri-implant soft tissue dehiscence . •Thin gingival phenotype. •Optimal compliance as evidenced by no missing treatment appointments and positive attitude towards oral hygiene.\n\nExclusion Criteria:\n\n* •Medically compromised patients and systemic conditions precluding implant and periodontal surgery. •Smokers, diabetics, pregnant or lactating women. •History of chemotherapy, radiotherapy in head and\u002For neck region. •Bisphosphonate therapy.","20 Years","50 Years",{"count":53,"type":23},[81],"PHASE2","Peri-implant soft tissue dehiscences represent a common complication in implant dentistry, often leading to esthetic and functional challenges. Current treatment options, including Xengenic cortical membranes and connective tissue graft with coronally advanced flap, aim to promote soft tissue regeneration and improve clinical outcomes. However, there is a need for comparative studies to determine the optimal treatment modality for peri-implant soft tissue dehiscences.",[30,84],"Connective Tissue Graft","2024-09-05",{"date":87,"type":36},"2024-09-19",{"date":66,"type":36},{"date":90,"type":23},"2024-12-30",{"name":92,"class":43},"Amr Anwar Mohamed Ellithy Yousef",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":24,"phases":102,"briefSummary":103,"conditions":104,"keywords":105,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":44},"100558511","evaluation-of-cross-linked-collagen-membrane-with-and-without-silk-fibroin-around-immediate-dental-implants-100558511","NCT06552065","Evaluation of Cross-linked Collagen Membrane With and Without Silk Fibroin Around Immediate Dental Implants","Comparative Evaluation of Cross-linked Collagen Membrane With and Without Silk Fibroin Around Immediate Dental Implants -Randomized Controlled Trial.","Inclusion Criteria\n\n* Systemically healthy patients in the age group of 18 to 55years.\n* Patients undergoing immediate implant placement with gingival thickness ≤ 1mm\n* Stage II \u002FStage III and Grade B Periodontitis patients.\n* Radiographic assessment using Radiovisiography (RVG) with grid.\n\nExclusion Criteria:\n\n* Patients having allergies with collagen and silk products.\n* Medical conditions contraindicating surgical interventions.\n* Known smokers and alcoholic.\n* Acute infections at the site of extraction. Ex Abscess.\n* Patients who have undergone radiotherapy or chemotherapy.","55 Years",{"count":53,"type":23},[26],"Comparative evaluation of cross-linked collagen membrane with and without silk fibroin around Immediate Dental Implants -Randomized controlled trial.",[30],[106],"Silk fibroin with collagen membrane","2024-08-12",{"date":109,"type":36},"2024-08-13",{"date":111,"type":23},"2024-09",{"date":113,"type":23},"2025-08",{"name":115,"class":43},"Krishnadevaraya College of Dental Sciences & Hospital"]