[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"implant-site-reaction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:implant-site-reaction":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,39,63,93,119,148,172],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100575773","perioperative-oral-vitamin-d3-supplementation-on-implant-osseointegration-100575773",false,"NCT06776640","Perioperative Oral Vitamin D3 Supplementation on Implant Osseointegration","Efficacy of Perioperative Oral Vitamin D3 Supplementation on Implant Osseointegration in Patients With Vitamin D Deficiency","OSIVID","Inclusion Criteria:\n\n* Male or female patient ≥ 18 years old, candidate for dental implant placement.\n* with vitamin D deficiency or insufficiency: 25(OH)D \\\u003C 25 ng\u002FL.\n* affiliated with a social security scheme.\n\nExclusion Criteria:\n\n* with a local contraindication for implant placement.\n* under guardianship, curatorship, or legal protection\n* Pregnant or breastfeeding women","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","The number of patients treated in Implantology at Nantes University Hospital is 400 per year. This pilot study aims to demonstrate the efficacy of a 6-month oral cholecalciferol supplementation on osseointegration in patients requiring dental implants and presenting with vitamin D deficiency, compared to French patients who have not undergone vitamin D screening",[25],"Implant Site Reaction","RECRUITING","2026-06-23",{"date":29,"type":30},"2026-06-24","ACTUAL",{"date":32,"type":30},"2025-01-15",{"date":34,"type":21},"2027-05-15",{"name":36,"class":37},"Nantes University Hospital","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":45,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":38},"100576307","peri-implant-mucosal-changes-over-time-following-implant-provisional-removal-in-the-esthetic-zone-100576307","NCT06783595","Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone","Inclusion Criteria:\n\n* Patient must have a maxillary anterior immediate implant and provisionalization treatment completed.\n* The adjacent tooth next to the implant should be a natural tooth\n* The temporary crown must have been in place for a minimum of 4 months\n* The patient needs to be of general good health, with no significant medical history or social habits that might directly affect the hard and soft tissue\n* Patient must have generally good oral hygiene without any history of gum disease or gum recession of other teeth around the region of interest\n\nExclusion Criteria:\n\n* Patient with an implant crown that has no teeth next to the implant crown\n* Patients who have an active gum disease",{"count":46,"type":21},34,"The study will examine the temporary volumetric change that happens in the gums around an implant crown when the crown is removed. The main question of the study is \"how much time has to pass to see a significant change, especially when there could be a need to make a mold of the surrounding gum to make a new crown?\"\n\nThe area of the implant crown will be scanned with an intra-oral scanner over a period of 15 minutes.",[49,25],"Tooth Loss",[51,52,53],"immediate implant placement","provisional","impression","2026-02-18",{"date":56,"type":30},"2026-02-20",{"date":58,"type":30},"2024-04-24",{"date":60,"type":21},"2026-12",{"name":62,"class":37},"Loma Linda University",{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":17,"minAge":18,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":79,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":38},"100571734","photofunctionalization-with-uvc-100571734","NCT06724107","Photofunctionalization With UVC","Effect of Photofunctionalization With on Titanium Dental Implants. A Pilot Sutdy","EPID","Inclusion Criteria:\n\n* Patients over 18 years of age.\n* Patients requiring dental implant surgery with or without bone or soft tissue regeneration surgery.\n* Acceptance of the informed consent document.\n\nExclusion Criteria:\n\n* Subjects with systemic diseases leading to untreated or uncontrolled haemostasis or coagulation disturbances.\n* Subjects with active infectious diseases (tuberculosis, HIV, syphilis, hepatitis, etc).\n* Patients under pharmacological treatment with monoclonal antibodies, bisphosphonates, chemotherapy or prolonged treatment with corticoids.\n* Patients with alcoholism or drug addiction.\n* Pregnant or breastfeeding women.",true,"65 Years",{"count":20,"type":21},"INTERVENTIONAL",[76],"NA","Summary:\n\nObjective: The general objective is to compare the placement of standard implants with a surface photofunctionalization technique based on ultraviolet C radiation (UVC), having as working hypothesis that this photofunctionalization will accelerate the bone apposition on the implant surface and increase the amount of bone that binds to the implant, making it possible to load these photofunctionalized implants in less time.\n\nDesign: Pilot, clinical, randomized, prospective, controlled, single-center, prospective study.\n\nScope of the study: Master's Degree in Oral Surgery and Implantology. Faculty of Dentistry. Complutense University of Madrid.\n\nSubjects of the study: patients attending the Master's Degree in Oral Surgery and Implantology for rehabilitation with dental implants, regardless of the sector in which they have missing teeth.\n\nKey words: ISQ (implant stability quotient), inmediate loading, UVC, dental implants.",[25],[80,81,82,83],"ISQ (implant stability quotient)","inmediate loading","UVC","dental implants","2024-12-06",{"date":86,"type":30},"2024-12-09",{"date":88,"type":21},"2024-12-12",{"date":90,"type":21},"2026-04-20",{"name":92,"class":37},"Universidad Complutense de Madrid",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":71,"sex":17,"minAge":100,"maxAge":72,"enrollmentInfo":101,"targetDuration":4,"studyType":74,"phases":103,"briefSummary":104,"conditions":105,"keywords":106,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":38},"100561483","evaluation-of-the-effect-of-osseodensefication-technique-versus-conventional-implant-drilling-technique-in-implant-supported-mandibular-overdenture-100561483","NCT06590753","Evaluation of the Effect of Osseodensefication Technique Versus Conventional Implant Drilling Technique in Implant Supported Mandibular Overdenture","Clinical and Radiographic Evaluation of the Effect of Osseodensefication Technique Versus Conventional Implant Drilling Technique on Supporting Structure in Implant Supported Mandibular Overdenture","Inclusion Criteria:\n\n* All patients will have edentulous.\n* Patient's age ranges from 55-65 years.\n* All patients should be free from any systemic disease such as bone diseases or debilitating diseases.\n* Patient's residual ridge should be covered with firm mucosa free from any signs of inflammation, ulceration, or flabby tissue.\n* Patients should have good oral hygiene.\n\nExclusion Criteria:\n\n* Uncooperative patients will be excluded .\n* Patient with parafunctional habits (bruxism, clenching)\n* Patient with xerostomia or excessive salivation.\n* Patient with TMJ disorder.","55 Years",{"count":102,"type":21},10,[76],"The present study will be performed to : evaluate the effect of two implant placement systems )conventional method and osseodensification method) radiographically on bone density and bone height surrounding the implant by using CBCT and clinically by probing depth and gingival index.",[25],[107,108,109],"implant","Bone density","Bone height","2024-09-10",{"date":112,"type":30},"2024-09-19",{"date":114,"type":30},"2022-12-01",{"date":116,"type":21},"2025-01-01",{"name":118,"class":37},"Badr University",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":38},"100555730","characterizing-the-inflammation-around-dental-implants-bacterial-infection-hypersensitivity-or-both-100555730","NCT06515886","Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?","Inclusion Criteria:\n\n* Received at least one functional implant (implant restored with a prothesis);\n* Did not receive peri-implant mucositis and peri-implantitis treatment in the past three months.\n\nExclusion criteria:\n\n* Dental records with incomplete information;\n* Individuals with a weak immune system or chronic disease such as diabetes, heart, lung or kidney disease;\n* Pregnant women;\n* Individuals undergoing orthodontic therapy and those who have oral piercing.\n* History of diseases that modify or suppress the immune and inflammatory response, including rheumatoid arthritis, diabetes, lupus, and inflammatory bowel disease and metastatic cancer;\n* Taking medications that cause antiresorptive osteonecrosis of the jaw (including any dose of intravenous bisphosphonates, oral bisphosphonate intake for more than three years, receptor activator of nuclear factor kappa-B ligand inhibitors, or antiangiogenic medications);\n* Taking medications known to induce gingival hyperplasia including anticonvulsants, immunosuppressants, or calcium channel blockers;\n* Taking steroid medications, systemic or local antibiotics in the last three months (as this may affect the interleukins activity);\n* Received radiation therapy to the head and neck or chemotherapy;\n* Received treatment to manage an inflamed implant, including management of peri-implantitis and peri-implant mucositis in the last three months.",{"count":126,"type":21},40,"The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs. The current study will investigate if the inflammation around the implant is due to bacterial infection, hypersensitivity or both.",[129,130,131,25],"Dental Implant Failed","Implant Complication","Implant Site Infection",[133,134,135,136,137,138],"Dental implant","Peri-implant inflammation","Inflammatory mediators","Bacterial infection","Hypersensitivity","peri-implantitis","2024-07-19",{"date":141,"type":30},"2024-07-23",{"date":143,"type":30},"2022-09-22",{"date":145,"type":21},"2025-12-01",{"name":147,"class":37},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":71,"sex":17,"minAge":18,"maxAge":154,"enrollmentInfo":155,"targetDuration":4,"studyType":74,"phases":156,"briefSummary":157,"conditions":158,"keywords":160,"overallStatus":163,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":168,"leadSponsor":170,"locationsCount":4},"100550408","radiographic-assessment-of-bone-gain-following-sinus-lifting-with-simultaneous-implant-placement-using-crestal-approach-with-membrane-control-technique-for-bone-augmentation-of-atrophied-maxillary-posterior-ridge-100550408","NCT06446687","Radiographic Assessment of Bone Gain Following Sinus Lifting With Simultaneous Implant Placement Using Crestal Approach With Membrane Control Technique for Bone Augmentation of Atrophied Maxillary Posterior Ridge","Inclusion Criteria:\n\n1. Patients required dental implant treatment in the posterior maxilla, in the premolar and molar regions ( both sexes).\n2. Residual bone height 4-8mm in the estimated implant positions.\n3. The bone width of the alveolar ridge is at least 5mm in estimated implant positions.\n4. The edentulous ridges are covered with optimal thickness of mucoperiosteum.\n\nExclusion Criteria:\n\n1. Patients with a systemically diseases or inflammation whether local or generalized.\n2. Patients with bleeding disorders.\n3. Subjected to irradiation in the head and neck area less than 1 year before implantation.\n4. Poor oral hygiene and motivation.\n5. Pregnant or nursing.\n6. Severe bruxism or clenching.\n7. Active infection or severe inflammation in the area intended for implant placement.\n8. Unable to open mouth sufficiently to accommodate the surgical tooling.","90 Years",{"count":102,"type":21},[76],"This study aims to evaluate the quantity and quality of the native and the newly bone around dental implants that's simultaneously installed with sinus lifting",[25,159],"Maxillary Deficiency",[161,162],"Closed Sinus lifting","Bone Gain","NOT_YET_RECRUITING","2024-06-01",{"date":166,"type":30},"2024-06-06",{"date":164,"type":21},{"date":169,"type":21},"2025-02-01",{"name":171,"class":37},"Cairo University",{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":4,"eligibilityCriteria":178,"healthyVolunteers":71,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":179,"targetDuration":4,"studyType":74,"phases":180,"briefSummary":181,"conditions":182,"keywords":183,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":190,"leadSponsor":192,"locationsCount":38},"100533455","effect-of-static-magnetic-field-on-dental-implant-stability-100533455","NCT06226038","Effect of Static Magnetic Field on Dental Implant Stability.","Effect of the Modified Magnetic Interim Denture on Dental Implant Stability and Marginal Bone Level: a Double-blind Randomized Controlled Trial Study","Inclusion Criteria:\n\n* healthy, complete edentulous area\n\nExclusion Criteria:\n\n* uncontrolled NCDs patients",{"count":102,"type":21},[76],"To evaluate the effect of static magnetic field on dental implant to bone integration.",[25],[184,133,185],"Static magnetic field","Bone healing","2024-05-13",{"date":188,"type":30},"2024-05-16",{"date":116,"type":21},{"date":191,"type":21},"2026-12-31",{"name":193,"class":37},"Mahidol University"]