[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"implant-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:implant-therapy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":5},"100641124","do-immediate-digital-workflows-increase-patient-value-100641124",false,"NCT07656597","Do Immediate Digital Workflows Increase Patient Value?","Do Immediate Digital Workflows Increase Patient Value? A Patient-Reported Outcome Measure-Based Randomized Controlled Trial Comparing Immediate Versus Delayed Digital Posterior Implant Workflows","ITI PROM RCT","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Indication for single implant therapy in a posterior premolar or molar extraction site.\n* Good oral hygiene with FMPS ≤20%.\n* Controlled periodontitis according to protocol definition.\n* At least one natural tooth adjacent to the implant site and presence of an antagonist tooth.\n* Ability to comply with study procedures and provide written informed consent.\n* Adequate bone volume for immediate or delayed placement.\n* Extraction site suitable for centrally positioned, prosthetically driven implant placement using straight prosthetic components.\n* Ability to achieve 3-4 mm circumferential implant engagement in native bone along the planned implant axis while maintaining safety distance from vital structures.\n* For molar sites, septal bone classified as Smith \\& Tarnow Type A or Type B, including cases requiring closed sinus floor elevation.\n* Post-extraction socket presenting as a contained or partially contained defect with at least three relatively intact socket walls and no individual socket wall vertical defect \\>5 mm.\n* No facial soft-tissue dehiscence or mucogingival defect associated with buccal bone dehiscence.\n\nExclusion Criteria:\n\n* • Known or suspected poor compliance, alcohol abuse, or substance abuse.\n\n  * Systemic or local contraindications to implant surgery.\n  * History of head\u002Fneck radiotherapy or recent malignancy within 5 years.\n  * Use of medications affecting bone metabolism.\n  * Bisphosphonate use within the past 5 years.\n  * Uncontrolled periodontal disease.\n  * Heavy smoking (\\>10 cigarettes\u002Fday).\n  * Pregnancy or lactation.\n  * Teeth with periapical lesions \\>5 mm in greatest diameter, or sockets demonstrating a large cortical perforation \\>5 mm in greatest dimension on CBCT.","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant rehabilitation. Participants will be randomized 1:1 to immediate implant placement at the time of tooth extraction or to delayed implant placement after approximately 16 weeks of healing following extraction and ridge preservation as indicated. The primary endpoint is oral health-related quality of life assessed longitudinally using the OHIP-14 questionnaire and analyzed as the model-based mean score averaged across the active treatment phase from baseline through definitive crown delivery. Secondary outcomes include workflow-related patient experience, chairside time, number of visits, postoperative pain, buccal contour changes based on intraoral scan-derived volumetric analysis, radiographic marginal bone level changes, implant survival, clinical peri-implant parameters, technical complications, esthetic outcomes, accuracy of guided implant placement, and clinician-reported workflow outcomes.",[27,28,29,30,31,32,33],"Dental Implant","Implant Therapy","Immediate Dental Implant Placement","Delayed Implant","Guided Surgery Accuracy","Patient-Reported Outcomes (PRO)","Single Tooth Dental Implant",[27,35,36,37,38,39,40,41,42,43],"immediate implant placement","delayed implant placement","digital workflow","guided surgery","patient-reported outcomes","OHIP-14","posterior implant rehabilitation","chairside time","volumetric analysis","NOT_YET_RECRUITING","2026-06-15",{"date":47,"type":48},"2026-06-18","ACTUAL",{"date":50,"type":21},"2026-08-03",{"date":52,"type":21},"2028-10-31",{"name":54,"class":55},"Heinrich-Heine University, Duesseldorf","OTHER",{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":17,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":22,"phases":68,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100574527","crestal-bone-changes-following-equi-crestal-versus-subcrestal-implant-placement-100574527","NCT06760442","Crestal Bone Changes Following Equi-crestal Versus Subcrestal Implant Placement","Radiographic Evaluation of Crestal Bone Changes Following Equi-crestal Versus Subcrestal Implant Placement in Mandibular Posterior Augmented Ridge. A Randomized Controlled Clinical Trial.","Inclusion Criteria:\n\n* Patients older than 21 years.\n* Patients having augmented (by 50\u002F50 particulate xenograft and autogenous bone) edentulous posterior site with vertical bone height of \\> 10 mm in the mandible with a width of ridge ≥ 7 mm\n\n  * Adequate Inter-arch space for implant placement\n  * Favorable occlusion (no traumatic occlusion).\n* Good oral hygiene.•Accepts 18 months follow-up period (cooperative patient)\n* The patient provides informed consent.\n\nExclusion Criteria:\n\n* Patients with inadequate bone volume and\u002F or quality\n* Patients with remaining roots or with signs of acute infection related to the area of interest.\n* Patients having systemic conditions that interfere with normal wound healing\n* Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits .\n* Smoker patients.\n* Pregnant women.",true,"21 Years","60 Years",{"count":67,"type":21},28,[24],"Statement of problem: The stability of peri-implant bone is a crucial factor for the long-term success of dental implants, where crestal bone plays a significant role in both the primary as well as the long- term implant stability. A bone loss of 1.5 mm during the first year of loading has been acceptable according to the early standards. However, more bone stability can be expected with the development in implant designs and surfaces over the past decades.\n\nAim of the study: the aim of this study is to radiographically assess the crestal bone changes following delayed implant placement in mandibular previously augmented posterior sites, comparing cases with equicrestal implant placement with subcrestal implant placement",[28,71],"Augmentation, Alveolar Ridge",[73,74,75,76,77],"crestal bone level changes","subcrestal implant position","crestal implant position","augmented ridge","dental implants","RECRUITING","2026-01-26",{"date":81,"type":48},"2026-01-27",{"date":83,"type":48},"2025-01-01",{"date":85,"type":21},"2026-12-01",{"name":87,"class":55},"Misr International University",1]