[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"implementation-science\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:implementation-science":32},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,26,0,25,[9,48,72,107,142,178,213,239,271,312,349,384,408,434,475,514,546,574,600,625,652,696,724,744,766],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100577620","home-based-self-sampling-for-cervical-cancer-prevention-education-intervention-in-ghana-100577620",false,"NCT06800664","Home-based Self-sampling for Cervical Cancer Prevention Education Intervention in Ghana","The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention Among Women Living With HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial","HOPE-inG","Inclusion Criteria:\n\nGeneral criteria\n\n* ability to give consent per Institutional Review Board stipulations\n* residing in the Central Region\n* having no medical characteristics that would interfere with the ability to participate fully\n* the willingness to participate in this study.\n\n  (a) Healthcare provider eligibility: Inclusion criteria include an individual (no gender restrictions) who\n* possesses healthcare qualifications (i.e., patient navigators, physicians, nurses, health facility management),\n* works at the HIV health facility at study sites,\n* is ≥18 years old. (b) Eligibility for women living with HIV (Patients)\n* identified female at birth) who\n* are living with HIV between 25 and 65 years old (age consistent with WHO CC screening guidelines)\n* have never had CC screening (Pap or HPV test),\n* have not had a screening for the past 5 years\n\nExclusion Criteria:\n\n* Women will be excluded if they are pregnant or have had a hysterectomy.\n* WLWH who have a cervix are the main target population to develop the HOPE toolkit.\n* Women who are below 25 and those who are above 65 years will be excluded.","ALL","25 Years","65 Years",{"count":22,"type":23},1500,"ESTIMATED","INTERVENTIONAL",[26],"NA","The investigators propose to develop and\u002For adapt implementation strategies and a structured implementation plan to translate the HOPE intervention into existing healthcare practice in Ghana.\n\nThese \"implementation support strategies (ISS)\" are implementation strategies relevant to implementation support, which is concerned with moving (implementation) research into (implementation) practice.\n\nThe ultimate goal is to facilitate health system adoption and sustainment.",[29,30,31,32,33,34],"Cervical Cancer Screening","HIV","Self-sampling","Implementation Science","Intervention (Training) Condition","Implementation Strategies","RECRUITING","2026-06-30",{"date":38,"type":39},"2026-07-01","ACTUAL",{"date":41,"type":39},"2025-11-11",{"date":43,"type":23},"2029-05",{"name":45,"class":46},"Baylor University","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":24,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":47},"100529969","enhancing-team-effectiveness-for-a-collaborative-school-based-intervention-for-adhd-100529969","NCT06180681","Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD","Inclusion Criteria:\n\n1. Youth ages of 7-11 years (2-5th grade) who are attending a participating school\n2. Child referred by a school mental health provider (SMHP) with apparent ADHD-related problems,\n3. ≥6 symptoms (item score ≥2) of Inattention or Hyperactivity-Impulsivity on the pooled parent and teacher Child Symptom Inventory\n4. ≥3 on the Impairment Rating Scale by parent and teacher (cross-situational impairment)\n5. Caretaker and teacher consent to participate in treatment and child provides assent.\n\nExclusion Criteria:\n\n1. No presence of conditions that are incompatible with this study's treatment including: severe visual or hearing impairment, severe language delay or intellectual impairment, psychosis, pervasive developmental disorder\n2. Child is in an all-day special education classroom (children in these classrooms are frequently receiving intensive behavior modification programs such that the intervention would be expected to require modification for use in these settings)\n3. Parent\u002Fprimary caregiver or child does not read or speak English or Spanish. Note: Participants will need to be able to read\u002Fspeak English or Spanish because all measures are in English or Spanish, and the intervention will be conducted in English or Spanish. Parents will be given the option of having a research staff member assist them in completing the assessment measures.\n4. Children planning to change (start or stop) psychotropic medication Note: Children taking medication will be required to meet all entry criteria, including impairment criteria, thus indicating a need for the intervention. Children taking medication for attention or behavior are eligible as long as their medication regimens are stable.","7 Years","11 Years",{"count":57,"type":23},144,[26],"The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and optimize its effectiveness. The investigators will tailor three empirically-supported team development interventions, Team Charters, Team Communication Training (Student Handoff Protocols), and Team Performance Monitoring, and integrate them into a team-enhanced CLS implementation protocol (CLS-T). Team Charters are a written document developed collaboratively by the team at the outset of their work together outlining expectations, goals, roles and responsibilities, and relevant policies and procedures for team collaborative operations. Research shows that Team Charters strengthen affective emergent states, such as trust and cohesion among team members, as well as cognitive emergent states, such as shared mental models. They also strengthen team processes, such as goal specification, communication, and coordination to optimize team effectiveness. Handoff protocols are widely used interventions for ensuring continuity in patient care and minimizing errors in medical settings. They have also been found to improve affective (e.g., trust, cohesion) and cognitive (e.g., shared mental models, situation awareness) emergent states among team members, enhancing team communication and coordination. Finally, Team Performance Monitoring provides feedback to teams that can motivate performance, provide opportunities for adaptation in the event of challenges, and prompt communication among team members. The investigators will conduct a Hybrid Type III cluster randomized trial in 24 schools in two large urban school districts, to evaluate whether CLS-T implementation results in improved implementation outcomes and child outcomes in comparison to standard CLS implementation.",[61,62,63,32],"Team-effectiveness Research","School-based Interventions","Attention Deficit\u002F Hyperactivity Disorder","2026-06-29",{"date":36,"type":39},{"date":67,"type":39},"2024-01-01",{"date":69,"type":23},"2028-01",{"name":71,"class":46},"University of California, San Diego",{"id":73,"slug":74,"hasResults":12,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":12,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":24,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":47},"100644875","remote-virtual-inspiration-vitality-and-energy-100644875","NCT07675681","REmote Virtual Inspiration: Vitality and Energy","Improving Cardiometabolic Health With Meditative Movement in Mobility Impaired Women","REVIVE","Inclusion Criteria:\n\n* Self-identify as a woman.\n* Age 35-64 years.\n* Mobility impairment lasting at least 1 year.\n* Regular use of a mobility aid (e.g., wheelchair, scooter, walker, cane, crutches, or other assistive device).\n* Community dwelling.\n* Able to demonstrate sufficient upper-extremity mobility to participate in seated Tai Chi\u002FQigong activities.\n* Access to a smartphone, tablet, or computer with internet access.\n* Willing to wear a study-provided wearable device and complete study assessments.\n* Reside in the United States.\n* Waist circumference ≥ 33 inches (84 cm).\n* Perceived Stress Scale (PSS) score ≥ 15.\n* Insomnia Severity Index (ISI) score ≥ 8.\n* Emotional eating indicated by a score \\\u003C 3 on the Mindful Eating Questionnaire (MEQ) Emotional Response subscale.\n* Able to understand written and spoken English.\n* Able to provide informed consent.\n* Able to provide healthcare provider approval for participation.\n\nExclusion Criteria:\n\n* Medical conditions that would make participation unsafe, as determined during screening.\n* Inability to safely perform seated upper-body movements.\n* Current participation in a structured Tai Chi, Qigong, or similar meditative movement program.\n* Pregnancy, lactation, or plans to become pregnant during the study period.\n* Cognitive, visual, auditory, or other impairments that would preclude completion of study procedures.\n* Implanted cardiac devices or implanted electronic devices that interfere with physiologic measurements.\n* Severe arrhythmia, left ventricular assist device (LVAD), or other conditions that interfere with heart rate variability assessment.\n* Use of sleep medications three or more times per week.\n* Medical conditions or medications that substantially affect autonomic nervous system activity, sleep, or stress-related outcomes.\n* Uncontrolled cardiovascular, neurological, psychiatric, or other serious medical conditions that would preclude safe participation.","FEMALE","35 Years","64 Years",{"count":84,"type":23},280,[26],"REVIVE is a randomized controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi\u002FQigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with mobility impairments.\n\nWomen with mobility impairments experience higher rates of obesity, cardiometabolic disease, chronic stress, sleep disturbances, and mental health concerns compared with women without disabilities. Limited access to accessible physical activity programs and barriers to participation in traditional exercise interventions contribute to these health disparities. Tai Chi and Qigong are gentle mind-body practices that may improve physical and psychological health through movement, breathing, and mindfulness techniques and can be adapted for individuals with limited mobility.\n\nParticipants will be randomized to either a seated Tai Chi\u002FQigong intervention or a health education video control condition. During the 12-week intervention phase, participants will receive daily video-based content delivered remotely. Participants assigned to the Tai Chi\u002FQigong group will engage in seated meditative movement practices, while participants assigned to the control group will receive health and wellness education videos unrelated to physical activity or nutrition behavior change.\n\nOutcomes will be assessed remotely at baseline, post-intervention, and follow-up. Primary outcomes include waist circumference and indicators of physiological stress regulation, including heart rate variability and salivary cortisol. Secondary outcomes include perceived stress, emotion regulation, depression, anxiety, emotional eating, sleep quality, and sleep disturbance. Additional measures collected through wearable technology, sleep diaries, questionnaires, and biological samples will be used to examine potential behavioral, psychological, and physiological mechanisms underlying intervention effects.\n\nThe findings from this study will contribute to the development of accessible, scalable, and evidence-based health promotion interventions designed to improve cardiometabolic health and overall well-being among women with mobility impairments.",[32,88,89,90,91],"Women Health","Disability Physical","Meditation","Tai Chi",[93,94,95,96,97,98],"Mobility Impairment","Tai Chi\u002FQigong","Cardiometabolic Health","Women with Disabilities","Stress Regulation","Sleep Health","2026-06-23",{"date":36,"type":39},{"date":102,"type":23},"2026-07",{"date":104,"type":23},"2030-08",{"name":106,"class":46},"Arizona State University",{"id":108,"slug":109,"hasResults":12,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":24,"phases":119,"briefSummary":120,"conditions":121,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":47},"100544950","k-orca-testing-a-decision-support-tool-and-group-process-for-selecting-interventions-100544950","NCT06375551","K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions","Refining and Pilot Testing a Decision Support Intervention to Facilitate Adoption of Evidence-Based Programs to Improve Parent and Child Mental Health","K-ORCA","Inclusion Criteria:\n\n* Non-institutionalized\n* Adults (18 years or older).\n* English-Speaking\n\nAim 1:\n\n* Involved in initial state decision-making related to Family First Prevention Services Act.\n* Willing to participate in two data collection occasions.\n\nAim 2:\n\n* Non-institutionalized\n* Adults (18 years or older). English-Speaking.\n* Involved in ongoing state decision-making related to Family First Prevention Services Act.\n* Willing to participate in three measurement occasions.\n\nAim 3:\n\n-Willing to participate in multiple (bi-weekly up to two years) measurement occasions.\n\nExclusion Criteria:\n\n-Not involved in or potentially influencing child welfare intervention decisions",true,"18 Years",{"count":118,"type":23},80,[26],"This proposal responds to NIMH Objective 4.2.c to develop \"decision-support tools and technologies that increase the effectiveness and continuous improvement of mental health interventions\" by leveraging the Family First Prevention Services Act (FFPSA) policy opportunity. First, a web-based platform to host (a) a decision-support tool and (b) automated facilitation for group decisions with the tool will be developed with state partners' feedback. Next, decision makers leading their states' FFPSA quality improvement efforts will be engaged to pilot a decision-support intervention comprised of the tool and live or automated facilitation, and to evaluate the implementation quality of evidence-based programs adopted with the decision-support intervention.",[122,123,124,125,126,127,32,128,129,130,131,132],"Child Abuse","Decision Making","Child Welfare","Decision Making, Shared","Decision Support Technique","Social Facilitation","Policy","Organizations","Consensus","Mental Health","Family","2026-06-16",{"date":135,"type":39},"2026-06-18",{"date":137,"type":23},"2026-12-01",{"date":139,"type":23},"2027-07-31",{"name":141,"class":46},"Chestnut Health Systems",{"id":143,"slug":144,"hasResults":12,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":4,"eligibilityCriteria":148,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":24,"phases":151,"briefSummary":152,"conditions":153,"keywords":163,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":47},"100605188","cardiac-point-of-care-ultrasound-training-pathway-for-emergency-department-advanced-practice-providers-100605188","NCT07159269","Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers","Cardiac Point-of-care Ultrasound Clinical Training Pathway Implementation and Impact Assessment for Advanced Practice Providers in the Emergency Department","Inclusion Criteria:\n\n* advanced practice providers (APPs) currently working in our ED, with additional APPs as they are hired (expected to be about 75 APPs total within the next 3 years due to expanding staffing needs and coverage models).\n\nExclusion Criteria:\n\n* non-APPs such as physicians, nurses, or other clinical staff",{"count":150,"type":23},75,[26],"The aim of this study is to assess emergency medicine physician and advanced practice provider (APP) knowledge and technical skill in performance of a point-of-care ultrasound simulation and just-in-time training pathway to determine the feasibility, acceptability, and usability of the ultrasound training program. By performing this study, we hope to create a standardized training model which could potentially facilitate point-of-care ultrasound (POCUS) clinical performance and thereby improve patient care.",[154,155,156,157,158,159,160,161,162,32],"Cardiovascular Disease Acute","Emergency Department Patient","Heart Failure Acute","Pulmonary Embolism (Diagnosis)","Point of Care Ultrasound (POCUS)","Cardiac Tamponade","Pericardial Effusion","Diagnostic Imaging","Medical Training",[164,165,166,167,168],"point of care ultrasound","focused cardiac ultrasound","advanced practice provider training","medical education","implementation science","2026-06-01",{"date":171,"type":39},"2026-06-03",{"date":173,"type":39},"2025-11-13",{"date":175,"type":23},"2030-06-30",{"name":177,"class":46},"Duke University",{"id":179,"slug":180,"hasResults":12,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":184,"eligibilityCriteria":185,"healthyVolunteers":12,"sex":18,"minAge":186,"maxAge":116,"enrollmentInfo":187,"targetDuration":4,"studyType":24,"phases":189,"briefSummary":190,"conditions":191,"keywords":198,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":47},"100608922","parents-helping-parents-for-youth-vaping-cessation-100608922","NCT07207850","Parents Helping Parents for Youth Vaping Cessation","Parents Helping Parents for Youth Vaping Cessation (PhP-VX)","PhP-VX","ADOLESCENT INCLUSION:\n\n* 15-18\n* Report vaping in the previous 30 days\n* English literacy\n\nPARENT INCLUSION:\n\n* Biological, adoptive, stepparents, or adult guardian of adolescent participating\n* Have face-to-face contact with the adolescent at least one day per week during the study period\n* Access to a computer or mobile phone at home\n* Interested in helping adolescent quit e-cigarette\u002Fvape use","15 Years",{"count":188,"type":23},200,[26],"The goal of this randomized controlled study is to test if this new intervention works to help adolescents quit vaping. A key feature of the program is the use of peer support for parents, delivered by trained parent coaches. Participants will complete baseline and follow up surveys. Parents in the intervention arm will receive peer support as part of the program.",[32,192,193,194,195,196,197],"Engagement, Patient","E Cigarette Use","Peer Support","Vaping Teens","Vaping Cessation","Parent Support",[199,200,201,202,203],"Vaping","Tobacco","vaping cessation","Parent support","adolescent vaping","2026-05-20",{"date":206,"type":39},"2026-05-26",{"date":208,"type":39},"2026-05-18",{"date":210,"type":23},"2027-08-31",{"name":212,"class":46},"University of Nebraska",{"id":214,"slug":215,"hasResults":12,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":4,"eligibilityCriteria":219,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":24,"phases":222,"briefSummary":223,"conditions":224,"keywords":227,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":4},"100640993","simulation-based-cardiac-point-of-care-ultrasound-program-to-improve-clinical-outcomes-in-acute-heart-failure-patients-100640993","NCT07592598","Simulation-Based Cardiac Point-of-Care Ultrasound Program to Improve Clinical Outcomes in Acute Heart Failure Patients","Co-design and Implementation of a Simulation-Based Cardiac Point-of-Care Ultrasound Program to Improve Clinical Outcomes in Acute Heart Failure Patients","Inclusion Criteria:\n\n* Emergency medicine provider practicing at the study site, including physician assistants and nurse practitioners\n\nExclusion Criteria:\n\n* ED nurses and technicians are excluded due to differing ultrasound training needs",{"count":221,"type":23},175,[26],"The aim of this study is to co-design a cardiac POCUS simulation training intervention and implementation strategy for EM clinicians and evaluate the effectiveness of the cardiac point-of-care ultrasound (POCUS) simulation-based training (CPST) and CPG implementation. By performing this study, the investigators hope to improve diagnostic processes and time-to-diuretic dosing for acute heart failure (AHF) patients.",[156,225,226,32],"Point-of-care Ultrasound","Simulation Training",[228,229,230,168],"acute heart failure","point-of-care ultrasound","simulation training","NOT_YET_RECRUITING","2026-05-11",{"date":208,"type":39},{"date":235,"type":23},"2026-09-01",{"date":237,"type":23},"2030-12-31",{"name":177,"class":46},{"id":240,"slug":241,"hasResults":12,"nctId":242,"briefTitle":243,"officialTitle":244,"acronym":245,"eligibilityCriteria":246,"healthyVolunteers":115,"sex":18,"minAge":20,"maxAge":4,"enrollmentInfo":247,"targetDuration":4,"studyType":24,"phases":249,"briefSummary":250,"conditions":251,"keywords":254,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":47},"100618817","reduction-of-low-value-prescribing-through-audit-and-feedback-100618817","NCT07336550","Reduction of Low-value Prescribing Through Audit and Feedback","AFFAP Trial: The Comparative Evaluation of Audit and Feedback-based De-implementation Strategies to Reduce Low-value Prescribing in Primary Care in Patients Over 65 Years of Age.","AFFAP","PRIMARY CARE CENTERS IN THE BARAKALDO-SESTAO INTEGRATED HEALTHCARE ORGANISATION OF OSAKIDETZA-BASQUE HEALTH SERVICE:\n\nInclusion Criteria:\n\n* collaboration is achieved from at least 51% of the General Practitioners (GP) or at least 4 GPs\n* At least 60 patients aged 65 years or older on at least one of the drugs of interest that may be potentially inappropriately prescribed\n\nExclusion Criteria:\n\n* N\u002FA\n\nPATIENTS ASSIGNED TO THE PARTICIPATING PC CENTERS:\n\nInclusion Criteria:\n\n* Patients over 65 years of age with any of the following unsuitability criteria:\n* PIP of benzodiazepines: patients on benzodiazepines for more than 3 months\n* PIP of proton pump inhibitors: patients on proton pump inhibitors for more than 8 weeks without a diagnosed gastrointestinal disease and with no long-term prescription of gastrotoxic drugs.\n* PIP of opioids: patients on opioids for non-cancer pain for more than 3 months.\n\nExclusion Criteria:\n\n* Patients who, in the opinion of the general practitioner, are not suitable candidates for tapering or discontinuation of the potentially inappropriately prescribed drug\n* Patients residing in care homes\n* Patients receiving palliative care",{"count":248,"type":23},540,[26],"The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on processes and outcomes, for reducing the rate of patients over 65 years of age with potentially inappropriate prescribing (PIP) of benzodiazepines, proton pump inhibitors and opioids.\n\nA closed-cohort stepped-wedge cluster-randomised trial will be conducted in nine PC centres from Barakaldo-Sestao Integrated Health Organization, Basque Health Service (Osakidetza). All health centre clusters will start under the control condition, and after an initial study period of 4 months in the control phase, one centre per step at 1-month intervals will be randomly assigned to crossover to the intervention, under which they will be exposed to an additional component of AF, namely, primary care pharmacist-led facilitation.\n\nMixed-methods analysis will be performed, gathering quantitative data to assess the results of the implementations at health centre and clinician levels, and qualitative data to assess the feasibility and perceived impact of the de-implementation strategies from the clinicians' perspective, and explore the experience and satisfaction of patients regarding the healthcare received.\n\nThis study will provide useful knowledge on the effect attributable to a more intensive AF strategy (facilitated AF) compared to standard procedures of AF reports, and of the characteristics of AF that are most effective.",[252,32,253],"Inappropriate Prescribing","Behavioral Sciences",[255,256,257,258,259,260,261],"low-value pharmacological prescription","De-implementation","Stepped-wedge design","Benzodiazepines","Proton pump inhibitors","Opioids","audit and feedback",{"date":263,"type":39},"2026-05-13",{"date":265,"type":23},"2026-06",{"date":267,"type":23},"2027-12",{"name":269,"class":270},"Basque Health Service","OTHER_GOV",{"id":272,"slug":273,"hasResults":12,"nctId":274,"briefTitle":275,"officialTitle":276,"acronym":277,"eligibilityCriteria":278,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":279,"targetDuration":4,"studyType":24,"phases":281,"briefSummary":282,"conditions":283,"keywords":298,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":308,"leadSponsor":310,"locationsCount":4},"100619558","communityrx-dementia--peer-navigation-crxdpeer-100619558","NCT07346183","CommunityRx-Dementia + Peer Navigation (CRxDpeer)","CommunityRx-Dementia + Peer Navigation (CRxDpeer): A Real-World Implementation and Effectiveness Study of an IT-Based Social Care Intervention","CRxDpeer","Inclusion Criteria:\n\n* Self-identifies as a caregiver of a home-dwelling person with Alzheimer's disease or related dementias (ADRD)\n* Resides in the target geographic region of the study\n* Has access to a cell phone and agrees to receive text messages from the study\n* Has an email address that they can receive emails from\n* Individuals under the age of 18 who are emancipated minors in the state of Illinois and a caregiver of a person with dementia\n\nExclusion Criteria:\n\n* Minors who are not emancipated in the state of Illinois.\n* Previously participated in the intervention arm of the CommunityRx-Dementia clinical trial",{"count":280,"type":23},330,[26],"The CRxDpeer intervention, delivered by a trained peer navigator, in practice called a \"peer mentor\", includes three evidence-based components: (a) focused education about common social (e.g., food and housing insecurity) and caregiving (e.g., respite and end of life care) needs, (b) activation of personalized community resource information for social and caregiving needs through delivery of a resource list (HealtheRx) at the baseline encounter and coaching on how to communicate with service providers, coordinate services and manage social support (e.g., connect with their peer navigator, reach out to friends or relatives for support, identify support groups, etc.) and (c) ongoing navigation-focused support meant to boost the baseline intervention, including a series of proactive text messages over 12 months. During this time, the subject can respond to and communicate with the peer navigator for ongoing support.",[284,285,286,287,288,289,290,291,292,293,294,295,296,194,32,297],"Alzheimer s Disease","Dementia","Caregiver","Loneliness","Health-Related Social Needs","Social Care","Healthcare Utilization","End of Life Care","Caregiver Burden","Anxiety","Stress","Depression","Self-Efficacy","Advance Care Planning",[299,300,301,302,303],"resource navigation","peer navigator","peer mentor","social care","dementia caregiver","2026-04-06",{"date":306,"type":39},"2026-04-07",{"date":169,"type":23},{"date":309,"type":23},"2029-02-28",{"name":311,"class":46},"University of Chicago",{"id":313,"slug":314,"hasResults":12,"nctId":315,"briefTitle":316,"officialTitle":317,"acronym":4,"eligibilityCriteria":318,"healthyVolunteers":115,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":319,"targetDuration":4,"studyType":24,"phases":321,"briefSummary":322,"conditions":323,"keywords":334,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":340,"lastUpdatePostDateStruct":341,"startDateStruct":343,"completionDateStruct":345,"leadSponsor":347,"locationsCount":47},"100619127","implementation-facilitation-of-exercise-is-medicine-greenville-100619127","NCT07340580","Implementation Facilitation of Exercise is Medicine Greenville","Facilitating Health System Implementation of Physical Activity Screening and Referral to Community-Based Programs: Exercise is Medicine Greenville","The primary aim of this study is implementation facilitation at the clinic level. The secondary aim of this study is at the patient level. Therefore we have divided our inclusion\u002Fexclusion eligibility criteria by primary and secondary aim.\n\n1\\. Clinic (primary aim) Inclusion criteria\n\n* Currently EIMG-activated Prisma Health-Upstate Primary Care clinic (family or internal medicine)\n* Adopted EIMG \\>= 6 months prior to the beginning of this study\n\nExclusion criteria\n\n* Not EIMG-activated\n* Adopted EIMG \\\u003C 6 months prior to the beginning of this study\n* Greater than 15 miles from the nearest YMCA\n\n  1\\. Primary care clinic staff (primary aim) Inclusion criteria\n* At least 18 years of age\n* Has worked at the Prisma Health-Upstate clinic since the start date of the intervention in the respective wave, i.e., Pre-IF start date for each wave\n* Has clinical encounters with a minimum of 25 patients per month\n* Study clinic is their primary clinic (\\>50% of their working time)\n* Able to understand and communicate in English\n\nExclusion criteria\n\n* Less than 18 years of age\n* Work at the Prisma Health-Upstate clinic started after the Pre-IF phase began\n* Has clinical encounters with \\\u003C25 patients per month\n* Unable to speak or understand English\n* Adults unable to provide consent\n\n  2\\. Patient (secondary aim) Inclusion criteria (must meet all of below)\n* Age \\>= 18 and \\\u003C= 80 years\n* Clinically eligible (diagnosis of hypertension, dyslipidemia, obesity, diabetes, or physical inactivity) to receive an EIMG referral\n* A healthcare visit with an eligible encounter type (evaluation, telemedicine, consult, office visit, e-visit, follow-up, appointment, education, multidisciplinary visit, nutrition, occupational medicine-office visit)\n* A healthcare visit at a participating clinic\n\nExclusion criteria\n\n* Age \\\u003C 18 or \\> 80 years\n* Current referral to Physical therapy or occupational therapy\n* Current referral to cardiac, pulmonary, or oncology rehab\n* One of the following visit diagnoses listed below:\n\n  * Alzheimer's disease\n  * Amyotrophic lateral sclerosis\n  * angina or chest pain\n  * congenital stenosis of aortic valve\n  * congenital insufficiency of aortic valve\n  * moderate or severe persistent asthma\n  * typical or atypical atrial flutter\n  * autonomic dysreflexia\n  * acute bronchitis\n  * cerebral infarction\n  * encounter for chemotherapy\n  * chronic kidney disease (stage 3-5)\n  * end stage renal disease\n  * coma\n  * acute chronic obstructive pulmonary disease\n  * unspecified dementia\n  * dependence on renal dialysis\n  * trisomy 21\n  * pulmonary embolism\n  * venous embolism and thrombosis\n  * history of falling\n  * acute fracture\n  * left ventricular failure\n  * congestive heart failure\n  * hypertensive urgency, emergency or crisis\n  * diabetes with ketoacidosis\n  * chronic respiratory failure\n  * dependence on supplemental oxygen\n  * myocardial infarction\n  * osteoporosis with current fracture\n  * encounter for palliative care\n  * paraplegia or quadriplegia\n  * Parkinson disease\n  * pneumonia\n  * encounter for supervision of pregnancy\n  * encounter for radiation therapy\n  * serious mental illness (schizophrenia, psychotic disorder)\n  * homicidal or suicidal ideations\n  * sepsis\n  * injury of spinal cord\n  * presence of coronary stent\n  * dependence on wheelchair or ambulatory aid\n\nFor patients completing accelerometry data collection, the additional inclusion\u002Fexclusion criteria apply:\n\nInclusion criteria:\n\n* Received an EIMG referral and scheduled for orientation\n* Attending orientation at two pre-determined community PA facilities (these sites were selected due to each being the largest urban and rural YMCA referral sites in the study)\n\nExclusion criteria:\n\n* Unable to provide verbal informed consent\n* Planning on travel or vacation during data collection, as patient PA behavior is anticipated to differ from 'everyday' PA behavior at home\n* Unable to wear a watch during work hours due to employment restrictions e.g., food service, healthcare, operating heavy machinery\u002Fconstruction, laboratory-based work etc.\n\nIn addition, for patients completing interviews, the additional inclusion\u002Fexclusion criteria apply:\n\nInclusion criteria:\n\n\\- Received an EIMG referral\n\nExclusion criteria:\n\n* Unable to provide verbal informed consent\n* Unable to speak or understand English\n* \\\u003C18 years of age",{"count":320,"type":23},35,[26],"A public health priority exists for the U.S. healthcare sector to integrate physical activity (PA) as a part of the patient care model. This research will provide valuable information on facilitating optimal implementation of a clinic-to-community model that identifies, refers, and enrolls physically inactive patients to community-based PA programs for the prevention and treatment of chronic diseases. Further, this work will provide evidence on the cost-effectiveness of integrating PA in healthcare systems as a population health management strategy.",[324,325,326,327,328,329,330,331,332,333,32],"Physical Inactivity","Dyslipidemia","Obesity and Overweight","Hypertension","Diabetes","Health Care Delivery","Patients","Chronic Disease","Exercise","Physical Activity",[335,336,337,338,339],"Implementation Facilitation","Physical activity referral scheme","Effectiveness-implementation hybrid type 3","Pragmatic design","Stepped wedge","2026-03-27",{"date":342,"type":39},"2026-04-02",{"date":344,"type":23},"2026-05-01",{"date":346,"type":23},"2030-07-31",{"name":348,"class":46},"University of South Carolina",{"id":350,"slug":351,"hasResults":12,"nctId":352,"briefTitle":353,"officialTitle":354,"acronym":355,"eligibilityCriteria":356,"healthyVolunteers":12,"sex":18,"minAge":357,"maxAge":4,"enrollmentInfo":358,"targetDuration":4,"studyType":24,"phases":360,"briefSummary":361,"conditions":362,"keywords":371,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":381,"locationsCount":383},"100510689","evaluating-novel-healthcare-approaches-to-nurturing-and-caring-for-hospitalized-elders-100510689","NCT05929703","Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders","Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders (ENHANCE)","ENHANCE","Inclusion Criteria:\n\n* Provision of informed consent\n* At least 70 years of age\n* Anticipated length of hospital stay at least 72 hours\n* Family member or care partner available to be on-site in the hospital\n* At least one delirium risk factor (e.g., cognitive or functional impairment, dehydration, vision or hearing impairment)\n* Evaluable cognitive function at baseline (i.e., ability to complete baseline cognitive function assessment)\n\nExclusion Criteria:\n\n* Delirium on admission\n* Unable to communicate verbally (e.g., coma, mechanical ventilation)\n* Unable to participate fully in interventions (e.g., terminal condition, advanced dementia)\n* Staff safety concerns (e.g., violent behavior)\n* Cardiac or intracranial surgery (due to competing causes of delirium)","70 Years",{"count":359,"type":23},1900,[26],"The goal of this clinical trial is to compare the Hospital Elder Life Program (HELP) with a family-augmented version of HELP (FAM-HELP), that includes family members and care partners, for the prevention of delirium in older patients during hospital admission. The main objectives of the trial are the following:\n\n1. To compare the effectiveness of FAM-HELP and HELP in reducing both the incidence of delirium and its severity.\n2. To compare the effectiveness of FAM-HELP and HELP in improving patient- and family-reported outcomes.\n3. To explore the implementation context, process, and outcomes of the FAM-HELP program in diverse hospital settings.",[363,364,365,366,367,368,369,292,32,370],"Delirium","Neurocognitive Disorders","Mild Cognitive Impairment","Alzheimer Disease","Aging","Family Support","Family Members","Patient Satisfaction",[363,372,373,32],"Clinical Trial","Comparative Effectiveness Research","2026-03-20",{"date":376,"type":39},"2026-03-24",{"date":378,"type":39},"2023-12-04",{"date":380,"type":23},"2027-08",{"name":382,"class":46},"University of Michigan",7,{"id":385,"slug":386,"hasResults":12,"nctId":387,"briefTitle":388,"officialTitle":389,"acronym":4,"eligibilityCriteria":390,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":391,"targetDuration":4,"studyType":24,"phases":393,"briefSummary":394,"conditions":395,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":399,"lastUpdatePostDateStruct":400,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":406,"locationsCount":47},"100530280","implementation-pilot-of-preoperative-cga-before-major-surgery-100530280","NCT06184724","Implementation Pilot of Preoperative CGA Before Major Surgery","Implementation Pilot of Preoperative CGA Referral Process for Older Patients Undergoing Major Surgery","Inclusion Criteria:\n\n1. Patient aged 80 or older who is scheduled for an elective inpatient major surgery\n2. Providers working in a clinic (aged 18 and older) where pCGA is performed or a related anesthesia pre-operative clinic\n3. Surgeons (adults older than 18) with a patient aged 80 or older who is scheduled for an elective inpatient major surgery\n\nExclusion criteria:\n\n* None",{"count":392,"type":23},42,[26],"The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery. The main question it aims to answer is: Can the implementation package help give more people access to this resource? Participants will be in two groups: older adults who are planning a major surgery and their medical and surgical healthcare providers. The results will be compared to a historic baseline.",[396,397,398,32],"Surgery","Geriatric Assessment","Health Services Research","2026-03-18",{"date":401,"type":39},"2026-03-19",{"date":403,"type":39},"2026-01-28",{"date":405,"type":23},"2029-04",{"name":407,"class":46},"University of Wisconsin, Madison",{"id":409,"slug":410,"hasResults":12,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":4,"eligibilityCriteria":414,"healthyVolunteers":12,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":24,"phases":417,"briefSummary":418,"conditions":419,"keywords":424,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":427,"lastUpdatePostDateStruct":428,"startDateStruct":429,"completionDateStruct":431,"leadSponsor":432,"locationsCount":47},"100629762","impact-of-the-corrie-lipids-digital-health-program-on-lipid-optimization-100629762","NCT07478887","Impact of the Corrie Lipids Digital Health Program on Lipid Optimization","Corrie Lipids Program: Optimizing LDL-Cholesterol by Improving Awareness, Access, and Achievement","Inclusion Criteria:\n\n* Age ≥18 years\n* Uncontrolled LDL-C per AHA\u002FACC guidelines\n* At least 1 major cardiovascular risk factor, including: high risk for ASCVD (individuals who meet criteria for Lipid-Lowering Therapy (LLT) based on ASCVD risk assessment using the most up-to-date guidelines), known ASCVD or subclinical ASCVD based on imaging, clinically diagnosed familial hypercholesterolemia or LDL-C ≥190 mg\u002FdL, diabetes mellitus, history of statin-associated side effects\n* Has a primary care physician and\u002For cardiologist who can prescribe lipid therapy\n* Owns a smartphone and agrees to the End User License Agreement to use the digital health app\n* Provided informed consent before initiation of study-specific activities\n\nExclusion Criteria:\n\n* Motor, cognitive, auditory, or visual impairment limiting technology use\n* Does not speak English\n* Malignancy (except nonmelanoma skin cancers or cervical or breast ductal carcinoma in situ within the previous 5 years)\n* Pregnancy (positive pregnancy test, highly sensitive urine or serum), plan to become pregnant or donate eggs, breastfeeding or plan to breastfeed\n* Likely to not be available to comply with all required study procedures to the best of the patient's and investigator's knowledge\n* History or evidence of any other clinically significant disorder, condition, or disease that, in the opinion of the investigator, would pose a risk to patient safety or interfere with the study evaluation, procedures, or completion",{"count":416,"type":23},1000,[26],"The overall objective is to evaluate the effectiveness and implementation of the Corrie Lipids Program, a comprehensive digital health initiative designed to address critical gaps in lipid-lowering as a component of ASCVD treatment by delivering an intervention that combines a patient-facing smartphone app, clinician education and coaching, and seamless incorporation into clinical workflows.\n\nResearchers plan to assess this multicenter digital health initiative in approximately 1,000 adults with uncontrolled LDL-C and elevated ASCVD risk using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. The study will examine whether the program improves LDL-C goal attainment, app engagement, prescribing patterns, and LDL-C monitoring, while also identifying barriers and facilitators to implementation across sites.",[420,421,422,423,32],"Cardiovascular Risk","LDL-C","Lipids","Digital Health",[425,426],"Apolipoprotein B (apoB)","Lipoprotein-a (Lp(a)","2026-03-13",{"date":399,"type":39},{"date":430,"type":39},"2025-06-20",{"date":267,"type":23},{"name":433,"class":46},"Johns Hopkins University",{"id":435,"slug":436,"hasResults":12,"nctId":437,"briefTitle":438,"officialTitle":439,"acronym":440,"eligibilityCriteria":441,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":442,"targetDuration":4,"studyType":24,"phases":444,"briefSummary":445,"conditions":446,"keywords":449,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":467,"lastUpdatePostDateStruct":468,"startDateStruct":470,"completionDateStruct":472,"leadSponsor":474,"locationsCount":47},"100581581","data2action-oregon-project-supporting-data-driven-decision-making-for-substance-use-services-policy-and-overdose-prevention-100581581","NCT06852170","Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention","Supporting Data-driven Decision-Making to Support Substance Use Service Expansion Policies and to Prevent Overdoses","D2A Oregon","Inclusion Criteria:\n\nSample 1: Local or Regional Decision Makers\n\n* At least 18 years old\n* Has decision-making authority within their professional role related to substance use service delivery, including leadership responsible for developing policy (e.g. executive directors) OR middle-managers (e.g., case managers, supervisor) and front-line workers responsible for service delivery decisions OR Responsible for developing local or state policy related to substance use\u002Fbehavioral health and\u002For the criminal justice system OR Advises these decision makers (e.g., legislative staff, data analysts)\n\nThese individuals will be drawn from organizations with the following perspectives: behavioral health, public health, health payer, first responders, health advocacy.\n\nSample 2: State or Local Decision Makers\n\n* At least 18 years old\n* Has decision-making authority within their professional role related to substance use service delivery, including leadership responsible for developing policy (e.g. executive directors) OR middle-managers (e.g., case managers, supervisor) and front-line workers responsible for service delivery decisions OR Responsible for developing local or state policy related to substance use\u002Fbehavioral health and\u002For the criminal justice system OR Advises these decision makers (e.g., legislative staff, data analysts)\n\nExclusion Criteria:\n\n* None.",{"count":443,"type":23},341,[26],"Oregon's decision makers (e.g., community service providers, public health, justice, advocacy groups, payers) are calling for comprehensive, current, and trusted data to inform how they allocate resources to improve substance use services and mitigate the growing opioid and methamphetamine epidemics in their state. Consistent with the HEAL Data2Action call for Innovation projects that drive action with data in real-world settings, this study will refine and test the impact of a novel implementation strategy to engage cross- sector decision makers and make data that they identify as relevant to their decisions available to them in easy- to-use products. The proposed study aims to not only address critical knowledge gaps regarding how and when data can inform impactful, transparent decision-making, but to provide decision makers with the data that they need to achieve community-wide substance use prevention and treatment goals, including the increased delivery of high-quality, evidence-informed, services and the prevention of overdoses.",[447,125,32,123,129,448,128],"Substance Abuse","Substance-related Disorders",[398,450,451,447,32,452,453,454,128,125,129,455,456,457,458,459,460,461,462,463,464,465,466],"Sequential","Stepped Wedge","Decision making","Substance-related disorders","Substance abuse treatment centers","Focus Groups","Harm Reduction","Policy Making","Law Enforcement","User-Centered Design","Public Health","Opioid-Related Disorders","Naloxone","Methamphetamine","Health Disparate, Minority and Vulnerable Populations","Health Policy","Stakeholder engagement","2026-03-12",{"date":469,"type":39},"2026-03-16",{"date":471,"type":39},"2025-02-06",{"date":473,"type":23},"2028-08-31",{"name":141,"class":46},{"id":476,"slug":477,"hasResults":12,"nctId":478,"briefTitle":479,"officialTitle":480,"acronym":481,"eligibilityCriteria":482,"healthyVolunteers":12,"sex":18,"minAge":483,"maxAge":4,"enrollmentInfo":484,"targetDuration":4,"studyType":24,"phases":486,"briefSummary":487,"conditions":488,"keywords":497,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":508,"completionDateStruct":510,"leadSponsor":512,"locationsCount":47},"100598260","feasibility-of-choose-to-move-replacement-ready-100598260","NCT07069179","Feasibility of Choose to Move Replacement Ready","Choose to Move Replacement Ready: A Feasibility Trial of a Virtual Health-promoting Intervention for People Awaiting Total Hip or Knee Replacement Surgery","CTM-RR","Inclusion Criteria:\n\n1. Activity coach hired by the Active Aging Society (activity coaches must speak English to participate in the evaluation);\n2. English-speaking older adults (aged \\>=50 years) who participate in CTM-RR will be invited to participate in the evaluation\n3. Referral partner (People who work in a healthcare setting who refer patients into the program)\n\nExclusion Criteria:\n\n1. non-English speaking activity coach\n2. non-English speaking referral partner","50 Years",{"count":485,"type":23},60,[26],"Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada. Recently, the investigators adapted CTM for the \\>14000 people in BC who are on surgical waitlists for total knee replacement or total hip replacement (TKR\u002FTHR) for osteoarthritis (OA). The primary goal of this observational study is to learn if the adapted program, Choose to Move Replacement Ready (CTM-RR), is feasible to deliver to people with hip and\u002For knee osteoarthritis who are on surgical waitlists for TKR\u002FTHR.\n\nParticipants who enrol in CTM-RR will answer online survey questions about the program and about their physical activity, mobility, pain, function, quality of life, willingness to undergo surgery, overall perception of their joint condition, psychosocial health, self-efficacy, social isolation, loneliness, and sedentary time. CTM-RR activity coaches will also answer online survey questions about the program. CTM-RR participants, activity coaches, and referral partners will also participate in interviews about the program.",[489,490,491,492,493,494,495,32,324,496],"Osteoarthritis","Osteoarthritis (OA) of the Knee","Osteoarthritis, Hip","Total Knee Arthroplasty; Total Hip Arthroplasty","Mobility Limitation","Social Isolation or Loneliness","Pain","Sedentary Behaviors",[489,498,499,500,501,287,495,502,503,504,505],"Implementation science","Social isolation","Physical activity","Mobility","Joint replacement","Feasibility","Acceptability","Fidelity","2026-03-10",{"date":467,"type":39},{"date":509,"type":39},"2025-07-14",{"date":511,"type":23},"2028-03",{"name":513,"class":46},"University of British Columbia",{"id":515,"slug":516,"hasResults":12,"nctId":517,"briefTitle":518,"officialTitle":519,"acronym":520,"eligibilityCriteria":521,"healthyVolunteers":12,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":522,"targetDuration":4,"studyType":24,"phases":524,"briefSummary":526,"conditions":527,"keywords":531,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":539,"startDateStruct":541,"completionDateStruct":543,"leadSponsor":544,"locationsCount":47},"100589366","phase-4-implementing-low-barrier-hcv-treatment-in-a-jail-setting-100589366","NCT06953479","Implementing Low-Barrier HCV Treatment in a Jail Setting","MINMON-J: An Effectiveness Implementation Pilot Study Evaluating a Low-barrier Hepatitis C Treatment Model in a Jail Setting","MINMON-J","Inclusion Criteria:\n\n* Incarcerated individual at RIDOC\n* Age ≥ 18 years\n* Awaiting trial (i.e., not sentenced)\n* English speaking\n* Diagnosis of active HCV (HCV RNA \\>1000 IU\u002FmL within 90 days prior to study entry)\n* Treatment-naïve for current HCV infection\n* No cirrhosis (FIB-4 Score \\\u003C3.25 within 90 days prior to study entry)\n* Self-report of injection drug use\n* Ability and willingness to be contacted after jail release\n* Verbal commitment to continue medication after discharge\n* Desire to receive Sofosbuvir\u002FVelpatasvir (Epclusa)\n\nExclusion Criteria:\n\n* Cirrhosis (FIB-4 Score \\>3.25 within 90 days prior to study entry and\u002For clinical signs of cirrhosis)\n* Positive for Hepatitis B surface antigen\n* Actively pregnant or breastfeeding\n* Known allergy\u002Fsensitivity to study drug components\n* Acute or serious illness requiring hospitalization at enrollment\n* Documented severe persistent mental illness (SPMI) by RIDOC\n* Any clinical history of hepatic decompensation (e.g., ascites, SBP, HE, HRS, variceal bleeding)\n* HIV-positive with active or acute AIDS-defining opportunistic infection within 90 days",{"count":523,"type":23},40,[525],"PHASE4","The goal of this clinical trial is to learn whether a low-barrier treatment program can help people with hepatitis C virus (HCV) who are in jail start and complete treatment more easily. This study focuses on adults at the Rhode Island Department of Corrections who have active HCV and are awaiting trial.\n\nThe study asks:\n\n* Can a simplified, low-barrier HCV treatment program work in a jail setting?\n* Do participants finish treatment and get cured using this approach?\n\nAll participants will receive a 12-week course of the HCV medication sofosbuvir\u002Fvelpatasvir (Epclusa). If they are released before completing treatment, they will take the remaining doses with them. Community Health Workers (CHWs) will help support participants after release, including reminding them to take medications and helping them get follow-up lab work.\n\nResearchers will measure:\n\n* Whether participants are cured of HCV\n* Whether the treatment approach is easy to use (feasible), acceptable, and followed correctly (fidelity)\n* Whether the program could be used in other jails or expanded in the future\n\nThis study may help bring HCV treatment to more people in jail, reduce community spread of the virus, and support national goals to eliminate HCV.",[528,529,530,32],"HEPATITIS C (HCV)","Incarceration","Injection Drug Use",[532,533,534,535,536,537,168],"hepatitis c","incarceration","jail","injection drug use","minimal monitoring","MINMON","2026-02-26",{"date":540,"type":39},"2026-02-27",{"date":542,"type":39},"2025-06-11",{"date":380,"type":23},{"name":545,"class":46},"Lifespan",{"id":547,"slug":548,"hasResults":12,"nctId":549,"briefTitle":550,"officialTitle":551,"acronym":552,"eligibilityCriteria":553,"healthyVolunteers":12,"sex":18,"minAge":554,"maxAge":4,"enrollmentInfo":555,"targetDuration":4,"studyType":24,"phases":557,"briefSummary":558,"conditions":559,"keywords":563,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":565,"lastUpdatePostDateStruct":566,"startDateStruct":568,"completionDateStruct":570,"leadSponsor":572,"locationsCount":573},"100530297","behavioral-economic--staffing-strategies-in-the-icu-100530297","NCT06184945","Behavioral Economic & Staffing Strategies in the ICU","Behavioral Economic and Staffing Strategies To Increase Adoption of an Evidence Based Bundle in the Intensive Care Unit (BEST ICU): A Stepped Wedge Cluster Randomized Controlled Trial","BEST-ICU","Inclusion Criteria:\n\n* Age \\>19 years at time of ICU admission\n* Received invasive mechanical ventilation while in the ICU\n* Admitted to participating cluster ICU\n* ICU length of stay of at least 24 hours\n\nExclusion Criteria:\n\n* Patient who is admitted to the hospital who is already receiving chronic long-term mechanical ventilation from the home, assisted living, or long-term care setting\n* Prisoners","19 Years",{"count":556,"type":23},8100,[26],"The overarching goal of this study is to support the \"real world\" assessment of strategies used to foster adoption of several highly efficacious evidence-based practices in healthcare systems that provide care to critically ill adults with known health disparities. Investigators will specifically evaluate two discrete strategies grounded in behavioral economic and implementation science theory (i.e., real-time audit and feedback and registered nurse implementation facilitation) to increase adoption of the ABCDEF bundle in critically ill adults.",[32,363,560,561,562,495],"Critical Illness","Mechanical Ventilation Complication","ICU Acquired Weakness",[564],"ABCDEF bundle, delirium, intensive care, critical care, mechanical ventilation","2026-02-16",{"date":567,"type":39},"2026-02-19",{"date":569,"type":39},"2024-07-01",{"date":571,"type":23},"2028-04",{"name":212,"class":46},3,{"id":575,"slug":576,"hasResults":12,"nctId":577,"briefTitle":578,"officialTitle":579,"acronym":4,"eligibilityCriteria":580,"healthyVolunteers":12,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":581,"targetDuration":4,"studyType":24,"phases":583,"briefSummary":584,"conditions":585,"keywords":588,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":592,"lastUpdatePostDateStruct":593,"startDateStruct":595,"completionDateStruct":596,"leadSponsor":598,"locationsCount":4},"100624690","optimizing-implementation-of-the-intensive-diabetes-prevention-program-100624690","NCT07412912","Optimizing Implementation of the Intensive Diabetes Prevention Program","Optimizing Implementation of the Intensive Diabetes Prevention Program in District Health Centres: A Hybrid Type 3 Study to Enhance Recruitment and Retention for Prediabetes Management","Inclusion Criteria:\n\n* Being 18 years of age or above\n* Having a baseline HbA1c within the prediabetes range (6.0%-6.4%)\n* Holding a scheduled appointment at a DHC\n\nExclusion Criteria:\n\n* Having a diagnosis of diabetes mellitus\n* Currently using of oral hypoglycaemic agents or medications known to induce significant weight changes\n* Having medical conditions that would limit participation, such as active cancer or cognitive impairment",{"count":582,"type":23},170,[26],"The goal of this clinical trial is to explore the effectiveness and implementation outcomes of the optimized Intensive Diabetes Prevention Program (IDPP) in District Health Centres. The main questions it aims to answer are:\n\n* Do the implementation strategies - patient engagement system, structured training, and reminder systems - work better than usual approaches in terms of acceptability, adoption, appropriateness, feasibility, sustainability, and implementation cost?\n* Do patient health outcomes - HbA1c levels, BMI, lipid profile, quality of life, perception of empowerment, and health service utilization - stay the same or get better when these improved strategies are used compared to usual approaches?",[586,587,32],"Prediabetes","Diabetes Prevention",[589,590,591],"Intensive Diabetes Prevention Program","Behavioural determinants","Prediabetes management","2026-02-09",{"date":594,"type":39},"2026-02-17",{"date":169,"type":23},{"date":597,"type":23},"2027-12-31",{"name":599,"class":46},"The Hong Kong Polytechnic University",{"id":601,"slug":602,"hasResults":12,"nctId":603,"briefTitle":604,"officialTitle":605,"acronym":4,"eligibilityCriteria":606,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":607,"enrollmentInfo":608,"targetDuration":4,"studyType":24,"phases":610,"briefSummary":611,"conditions":612,"keywords":4,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":616,"lastUpdatePostDateStruct":617,"startDateStruct":619,"completionDateStruct":621,"leadSponsor":623,"locationsCount":47},"100504890","behavioral-economics-to-implement-nutrition-ranking-in-food-pantries-100504890","NCT05854212","Behavioral Economics to Implement Nutrition Ranking in Food Pantries","Behavioral Economics to Implement a Traffic Light Nutrition Ranking System in a Network of Food Pantries","Inclusion Criteria:\n\n* Food agencies that order food from the Greater Boston Food Bank (GBFB) online ordering platform.\n\nExclusion Criteria:\n\n* Food agencies that do not order food from the GBFB online platform within 2 months of the start of the study.","90 Years",{"count":609,"type":23},364,[26],"The goal of this randomized controlled trial is to test whether using behavioral economic strategies to promote healthy food choices on a food bank's online ordering platform increases the use of the traffic light nutrition ranking system and increases healthier food selections by the food agencies (e.g., food pantries) who use the food bank.",[613,614,615,32],"Food Insecurity","Dietary Quality","Behavioral Economics","2026-01-29",{"date":618,"type":39},"2026-02-02",{"date":620,"type":23},"2027-01-01",{"date":622,"type":23},"2028-06-30",{"name":624,"class":46},"Massachusetts General Hospital",{"id":626,"slug":627,"hasResults":12,"nctId":628,"briefTitle":629,"officialTitle":630,"acronym":631,"eligibilityCriteria":632,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":633,"targetDuration":4,"studyType":24,"phases":635,"briefSummary":636,"conditions":637,"keywords":643,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":644,"lastUpdatePostDateStruct":645,"startDateStruct":647,"completionDateStruct":649,"leadSponsor":650,"locationsCount":47},"100521862","the-p-kids-care-health-systems-intervention-in-tanzania-100521862","NCT06075108","The P-KIDs CARE Health Systems Intervention in Tanzania","P-KIDs CARE: An Intervention to Address Health Systems Delays to Care for Injured Children in Tanzania","P-KIDs CARE","Inclusion Criteria:\n\n* AIM 1 (mixed methods research)\n\n  1. Enroll into the pediatric injury registry all pediatric (\\\u003C18 years old) patients seeking care at one of the study health facilities for an acute injury.\n  2. The investigators will conduct in-depth interviews with the following group: Family members of a pediatric injury patients seeking care at the study facilities.\n  3. The investigators will conduct focus group discussions with the following group: Health care providers providing care to pediatric injury patients at the study facilities.\n* AIM 2 (develop intervention)\n\n  1. The investigators will hold a 2-day intervention development workshop with the interdisciplinary study team.\n  2. The investigators will conduct focus group discussions with the following groups:\n\n     1. Health care providers providing care to pediatric injury patients at the study health facilities\n     2. A community-engaged panel including family members of pediatric injury patients\n* AIM 3 (pilot intervention)\n\n  1. The investigators will enroll into the pediatric injury registry all pediatric (\\\u003C18 years old) patients seeking care at one of the study health facilities for an acute injury.\n  2. The investigators will conduct surveys and exit interviews with the following groups:\n\n     1. Health care providers providing care to pediatric injury patients at the study health facilities.\n     2. Family members of pediatric injury patients.",{"count":634,"type":23},284,[26],"The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g. patient assessment, stabilization, and disposition) for pediatric injury patients in Tanzania. This health systems intervention will work at the first level of medical contact (e.g., health center and district hospital), in order to facilitate timely disposition and referrals, and subsequently decrease time to definitive care. The proposed study has three aims: 1) With a mixed methods approach, describe the barriers to pediatric injury care at the first medical contact; 2) Iteratively develop the P-KIDs CARE intervention using a nominal group technique and conduct a pre-implementation assessment and refinement; 3) Pilot the P-KIDs CARE intervention and perform an implementation-focused formative evaluation. The proposed study focuses on pediatric injury patients and the family members and healthcare providers that care for them in Kilimanjaro, Tanzania. The investigators will recruit pediatric injury patients, family members, and healthcare providers from 2 health facilities in the Kilimanjaro Region.",[638,639,640,641,642,32],"Accidental Injuries","Global Child Health","Pediatric Emergency Medicine","Public Health System Research","Health Care Providers",[638,639,640,642,641,32],"2026-01-14",{"date":646,"type":39},"2026-01-16",{"date":648,"type":39},"2024-08-05",{"date":473,"type":23},{"name":651,"class":46},"University of Utah",{"id":653,"slug":654,"hasResults":12,"nctId":655,"briefTitle":656,"officialTitle":657,"acronym":658,"eligibilityCriteria":659,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":660,"targetDuration":4,"studyType":24,"phases":662,"briefSummary":663,"conditions":664,"keywords":677,"overallStatus":231,"whyStopped":4,"lastUpdateSubmitDate":686,"lastUpdatePostDateStruct":687,"startDateStruct":689,"completionDateStruct":691,"leadSponsor":693,"locationsCount":47},"100620350","enhancing-mental-and-physical-health-of-women-veterans-30-100620350","NCT07356479","Enhancing Mental and Physical Health of Women Veterans 3.0","Enhancing Mental and Physical Health of Women Through Engagement and Retention (EMPOWER) 3.0 (QUE 25-015)","EMPOWER","Inclusion Criteria:\n\n* This study is recruiting VA sites - not individual patients.\n* Prior to randomization, the study team will work with sites to ensure they have met the preconditions necessary to enroll in the study, which includes VISN, regional and\u002For facility level leadership support for participation.\n\nExclusion Criteria:\n\n* N\u002FA",{"count":661,"type":23},18,[26],"Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able to use those services. Furthermore, few VA improvement efforts have focused on women Veterans' health and health care in midlife. The EMPOWER QUERI 3.0 Program is a cluster randomized type 3 hybrid implementation-effectiveness trial testing two strategies designed to support implementation and sustainment of evidence-based practices for women Veterans in at least 18 VA facilities from 4 regions.",[665,666,667,327,668,669,670,671,672,673,674,675,32,676],"Cardiovascular Diseases","Overweight","Obesity","Cholesterol","Diabetes Mellitus","Prediabetic State","Menopause","Cognitive Behavioral Therapy","Primary Health Care","Stress Disorders, Post-Traumatic","Prevention","Quality Improvement",[678,666,667,327,668,669,670,671,672,673,674,675,498,676,679,680,681,370,682,683,684,685],"Cardiovascular diseases","Women","Veterans","Patient Participation","Patient Preference","Physicians, Primary Care","Physicians, Women","Health Behavior","2026-01-12",{"date":688,"type":39},"2026-01-21",{"date":690,"type":23},"2026-10-01",{"date":692,"type":23},"2031-09-30",{"name":694,"class":695},"VA Office of Research and Development","FED",{"id":697,"slug":698,"hasResults":12,"nctId":699,"briefTitle":700,"officialTitle":700,"acronym":701,"eligibilityCriteria":702,"healthyVolunteers":115,"sex":18,"minAge":703,"maxAge":4,"enrollmentInfo":704,"targetDuration":4,"studyType":24,"phases":706,"briefSummary":707,"conditions":708,"keywords":711,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":715,"lastUpdatePostDateStruct":716,"startDateStruct":718,"completionDateStruct":720,"leadSponsor":722,"locationsCount":7},"100587106","scale-up-of-an-evidence-based-adolescent-transition-package-to-support-transitional-care-among-youth-living-with-hiv-100587106","NCT06924073","Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV","ATTACH-Scale","Inclusion Criteria:\n\nHealthcare providers\n\n* ≥18 years of age\n* Employed at one of the 32 facilities in the RCT\n* Provides HIV services to adolescents affiliated within their clinic Adolescents and youth living with HIV\n* Between 15-24 years of age (focus group discussions, surveys) or between 10-24 years of age (offered the intervention)\n* Receives HIV clinical care at one of the clinics included in the study\n* Attended clinic ≥1 time following intervention implementation\n\nExclusion Criteria:\n\nAny individual who meets the following criteria will be excluded from participation in this study:\n\n\\- Conditions that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study","10 Years",{"count":705,"type":23},1920,[26],"Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment. The proposed implementation study will test a youth-led data-driven implementation strategy to scale-up an evidence-based Adolescent Transition Package (ATP) aimed at improving transition processes and post-transition clinical outcomes for youth living with HIV in Kenya. Clinics will be randomized to receive standard of care implementation through trainer of trainers or the youth-led data-driven implementation strategy alongside trainer of trainers. We will study whether the enhanced implementation strategy improves the number of youth who receive the ATP, the number of providers that initially chose to use the ATP, and the consistency with which the ATP is used over time. We will also evaluate the cost of the ATP and whether the ATP improves health outcomes among youth living with HIV, including viral suppression and retention in care. Healthcare workers at study sites will complete surveys, focus group discussions, interviews, and participate in continuous quality improvement processes. Youth will participate in surveys and focus groups, and have their routine medical records abstracted.",[709,710,32,34],"Adolescent HIV Infection","Transition to Adult Care",[712,710,713,498,714],"Adolescent HIV","Scale-up","implementation strategy","2025-11-12",{"date":717,"type":39},"2025-11-14",{"date":719,"type":39},"2025-10-16",{"date":721,"type":23},"2029-01-30",{"name":723,"class":46},"University of Washington",{"id":725,"slug":726,"hasResults":12,"nctId":727,"briefTitle":728,"officialTitle":728,"acronym":4,"eligibilityCriteria":729,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":730,"targetDuration":4,"studyType":24,"phases":732,"briefSummary":733,"conditions":734,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":736,"lastUpdatePostDateStruct":737,"startDateStruct":739,"completionDateStruct":741,"leadSponsor":743,"locationsCount":47},"100549700","asthma-crisis-in-paediatrics-impact-of-a-care-pathway-in-primary-and-hospital-care-100549700","NCT06437444","Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care","Eligibility for professionals:\n\n* Primary Care paediatricians and nurses\n* Paediatricians and nurses in the Paediatric Emergency Department\n* Paediatricians and nurses on the inpatient ward\n* Paediatric Intensive Care paediatricians and nurses\n* Paediatric Pneumology paediatricians and nurses\n\nEligibility for patients:\n\nPatients between 2 and 14 years,that have being attended between the 7 May 2023 and the 7 May 2025, and with an acute episode of asthma, defined as:\n\n* an episode of wheezing and a previous diagnosis of asthma or with a previous episode of wheezing\n* a first episode in a child older than 2 years with a personal\u002Ffamily history of atopy and\u002For with an objective response to bronchodilators as assessed by the Pulmonary Score",{"count":731,"type":23},249,[26],"This study aims to evaluate the effect of the implementation of the new Asthma Integrated Care Pathway in the Basque Healthcare Service for the improvement of care for children with asthma attacks and the reduction of variability between professionals and care settings in this care practice. Asthma is the most common chronic disease in children and has a major impact on people's quality of life. The Asthma Integrated Care Pathway is a structured multidisciplinary care plan that details the essential steps in the care of patients with mild-moderate asthma attacks and the coordinated practice of the agents involved as dictated by the evidence. This pathway will include quality indicators of compliance with diagnostic criteria, assessment of severity and prescription of drugs, as well as the experience of families and professionals, which have been collected in meetings designed for this purpose.\n\nThe study consists in a mixed methods implementation trial with two phases:\n\n1. Phase I: a quantitative evaluation will be carried out to assess implementation outcomes at the professional level through a pretest-posttest quasi-experimental study with paired control group, with a ratio of 1:2. The primary outcome variable will be the overall percentage of bronchodilator treatment with a spacer chamber in children diagnosed with mild-moderate asthma attacks. We will also include as outcomes to be measured the registration rate of the Pulmonary Score, the recording rate of the assessment of persistent asthma symptoms, and the rate of initiation of background treatment in children with persistent asthma symptoms. These variables will be analysed using differences in pre- and post-intervention outcome measures between the intervention and control groups.\n2. Phase II: a qualitative evaluation will be carried out through a structured process with discussion groups focused on the identification of the main barriers and facilitators for the provision of recommended clinical practice related to asthmatic crisis in mild-moderate cases established by the Asthma Integrated Care Pathway. A purposive sample of paediatricians stratified by level of care and service organisations will be recruited to ensure that all views are represented in the discussion groups. The structured script will be designed with questions to explore each of the domains of the Theoretical Domains Framework (TDF).\n\nThe study will be carried out mainly in two integrated healthcare organizations (IHO), which are made up of two primary care areas and the paediatric reference hospital emergency department of both areas, as well as the hospitalisation, intensive care and paediatric pneumology departments of said hospital, to extend in the future the Asthma Integrated Care Pathway to the rest of the Basque Health Service IHOs.",[735,32],"Asthma in Children","2025-09-16",{"date":738,"type":39},"2025-09-19",{"date":740,"type":39},"2023-05-07",{"date":742,"type":23},"2026-05-07",{"name":269,"class":270},{"id":745,"slug":746,"hasResults":12,"nctId":747,"briefTitle":748,"officialTitle":749,"acronym":4,"eligibilityCriteria":750,"healthyVolunteers":12,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":751,"targetDuration":4,"studyType":24,"phases":753,"briefSummary":754,"conditions":755,"keywords":757,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":759,"lastUpdatePostDateStruct":760,"startDateStruct":761,"completionDateStruct":762,"leadSponsor":764,"locationsCount":47},"100607125","validation-of-the-effectiveness-of-the-cfir---eric-matching-tool-in-implementation-research-100607125","NCT07184489","Validation of the Effectiveness of the CFIR - ERIC Matching Tool in Implementation Research","Validation of the Effectiveness of the CFIR - ERIC Matching Tool in Implementation Research of Pediatric Venous Access Device Selection","Inclusion Criteria:\n\n* Having worked at the research site for ≥ 1 year;\n* Being able to independently perform nursing operations (having completed the content related to intravenous infusion in the standardized training of this hospital and passed the assessment).\n\nExclusion Criteria:\n\n* Not having obtained the nurse practice license;\n* Refusing to participate in this study.",{"count":752,"type":23},394,[26],"The goal of this implementation study is to learn if the CFIR-ERIC matching tool is effective indeveloping implementation strategies for pediatric nurse. The evidence practised in this study is the pediatric venous access device selection decision tree from clinical practice guideline on infusion therapy in children. The main questions it aims to answer are:\n\n1. Does the implementation strategies developed by CFIR-ERIC matching tool improve nurses knowledge in venous access devices selection.\n2. Does the implementation strategies developed by CFIR-ERIC matching tool lower the error rate of appropriate venous access device selection.\n\nResearchers will compare the CFIR-ERIC group to a blank group to see if CIFR-ERIC matching tool works to improve nurses knowleged and lower the error rate of venous access device selection.\n\nParticipants will:\n\n1. Receive the implementation strategies made by CFIR-ERIC matching tool.\n2. Using the pediatric venous access device selection decision trees in daily catheterization.\n3. Record their venous access device selection informantion, consumables usage and pediatric patients' outcome.",[756,32],"Infusions, Intravenous",[714,758],"CFIR-ERIC","2025-09-15",{"date":738,"type":39},{"date":430,"type":39},{"date":763,"type":23},"2025-12-31",{"name":765,"class":46},"Children's Hospital of Fudan University",{"id":767,"slug":768,"hasResults":12,"nctId":769,"briefTitle":770,"officialTitle":771,"acronym":772,"eligibilityCriteria":773,"healthyVolunteers":115,"sex":18,"minAge":116,"maxAge":4,"enrollmentInfo":774,"targetDuration":4,"studyType":24,"phases":776,"briefSummary":777,"conditions":778,"keywords":781,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":785,"lastUpdatePostDateStruct":786,"startDateStruct":788,"completionDateStruct":790,"leadSponsor":792,"locationsCount":794},"100530878","implementing-a-novel-consent-process-for-biospecimen-research-after-newborn-screening-100530878","NCT06192511","Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening","Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening in Hospitals Serving Diverse Patients","MICI","Inclusion Criteria:\n\n* Adult (\\> 18 years)\n* English, Spanish or Arabic speaking\n* Just gave birth and currently a patient in the Mother \\& Baby Unit in the hospital\n\nExclusion Criteria:\n\n* Parents of infants who are born pre-term (\\\u003C 37 weeks gestation)\n* Parents of infants in the Neonatal Intensive Care Unit\n* Parents of infants being put up for adoption or in situations where legal guardianship is unknown at the time of birth",{"count":775,"type":23},5980,[26],"The purpose of this study is to implement an electronic consent education process for the retention and research use of residual dried bloodspots at four hospitals in Michigan and assess the impact of the new education, both on patients and hospital staff. The research team will recruit women who have just given birth to answer surveys about the Michigan BioTrust consent process. Surveys will be collected from participants in the hospital and again four weeks later. The research team will collect survey data from patient participants at each hospital prior to hospital staff implementation of the new education process and again after staff implementation.",[32,779,780],"Informed Consent","Neonatal Screening",[782,783,784],"newborn screening","informed consent","biobanking","2025-06-16",{"date":787,"type":39},"2025-06-19",{"date":789,"type":39},"2024-05-15",{"date":791,"type":23},"2028-04-30",{"name":793,"class":46},"Erin Rothwell",2]