[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"impulsivity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:impulsivity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,45,74,113,153,179,205],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100320866","shaping-tolerance-for-delayed-rewards-100320866",false,"NCT03457402","Shaping Tolerance for Delayed Rewards","Feasibility of Shaping Tolerance for Delayed Rewards in Impulsive 3-6 Year Olds","DelTA","Inclusion Criteria:\n\n* Age 3-6 years\n* Hyperactivity\u002FImpulsivity subscale scores of the ADHD Rating Scale-IV Preschool Version (children 3 to 4 years of age) or the Attention and Behavior Scale (children 5 to 6 years of age) ≥ 90th percentile from either the parent or teacher's responses\n* Physically and visually able to use the tablet, as determined by pre-assessment performance\n* Children taking psychotropic medication will be included, but must maintain the same medication and dose over the course of the study and for each assessment and exhibit elevated levels of impulsivity based on parent or teacher ratings while medicated.\n\nExclusion Criteria:\n\n* Children with autism spectrum disorder and\u002For intellectual disability (by parent or teacher report or the NIH Toolbox Picture Vocabulary Test).","ALL","3 Years","6 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","Deficits in self-control are of major public health relevance as they contribute to several negative outcomes for both individuals and society. For children, developing self-control is a critically important step toward success in academic settings and social relationships, yet there are few non-pharmacological approaches that have been successful in increasing self-control. We found in our earlier studies that self-control can be increased in preschool-aged children with high impulsivity by using games in which they practice gradually increasing wait-time for larger, more delayed rewards. We are performing this current study to test if this training to increase self-control can be increased using mobile app technology, with computerized game time being used as a reward.",[28],"Impulsivity",[30,31],"delay discounting","shaping","RECRUITING","2026-06-02",{"date":35,"type":36},"2026-06-04","ACTUAL",{"date":38,"type":36},"2017-09-12",{"date":40,"type":22},"2026-08",{"name":42,"class":43},"University of California, Davis","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100640267","intensive-neurofeedback-protocol-for-children-with-adhd-a-proof-of-concept-study-comparing-iapf-personalized-and-standard-theta-beta-ratio-training-100640267","NCT07595783","Intensive-neurofeedback Protocol for Children With ADHD: A Proof-of-concept Study Comparing iAPF-personalized and Standard Theta-beta-ratio Training","Inclusion Criteria:\n\n* Children aged 6-13 years. Confirmed ADHD diagnosis (ICD 10: F90.0, F90.1, or F98.8)\n* German-speaking children with normal or corrected vision.\n\nExclusion Criteria:\n\n* Children with neurological disorders (e.g., Epilepsy)\n* Children without an ADHD diagnosis\n* Caregivers with inability to provide informed consent or complete questionnaires\n* Participation in neurofeedback that was conducted in the year prior to the intended participation or is still ongoing.\n\nThe intake of medication or psychotherapeutic treatments and ICD-10 diagnosis are queried at T1, T2 and T3. These are recorded as control variables and are not exclusion criteria. The medication intake was kept constant during the NF training.","13 Years",{"count":53,"type":22},40,[25],"The first aim of this clinical trial is to test the feasibility and signal validity of a new approach to neurofeedback training (NF) using intensive EEG-based theta-beta NF for children with ADHD in the context of NF camps during school holidays. The second aim is to compare the efficacy of two neurofeedback protocols in reducing ADHD symptoms. Previous study results highlight that children with ADHD frequently show increased Theta-Beta-Ratios (TBR) in the qEEG, probably associated with attention difficulties, which may be ameliorated following neurofeedback training. However, the current state of research shows heterogenous findings regarding the efficacy of standard TBR NF for children with ADHD. Further study results suggest that personalized NF training protocols, based on the individual alpha peak frequency (iAPF), may be more effective in reducing ADHD symptoms than standardized ones.\n\nTherefore, in this proof-of-concept study of children with ADHD a standard TBR NF protocol is compared with an iAPF-personalized TBR NF (iAPF-TBR NF) protocol (based on the previously obtained iAPF). The study is designed as a randomized controlled intervention trial (RCT) with three assessment points (pre \\[T1\\], post \\[T2\\] and 6-month follow-up \\[T3\\]). Primary endpoints include the reduction of ADHD symptoms assessed by parent-, teacher- and self-report questionnaires. Furthermore, it is hypothesized that NF training is associated with better performance in a sustained attention and executive function test and a reduced TBR in qEEG, particularly following iAPF-TBR NF.\n\nThe main questions are:\n\n* Is it feasible to train groups of up to 12 children with two sessions NF per day for an eight-day-period during their school holidays?\n* Does iAPF-TBR NF provide a valid neuromodulatory signal compared to the standard-TBR-NF protocol? Do the frequency boundaries demonstrate spectral stability across the 16 training sessions?\n* Does the personalized iAPF-TBR NF training reduce ADHD symptoms measured immediately after the training more than standard-TBR-NF training? (comparison T2-T1)\n* Does the personalized iAPF-TBR NF training reduce ADHD symptoms measured 6 months after the NF training more than standard TBR-NF training? (comparison T3-T1)\n* Does the reduction in ADHD symptoms measured immediately after the NF-training persist until the 6-month follow-up? Do possible differences between iAPF-TBR NF training and standard TBR NF training remain? (comparison T3-T2)\n\nPost-hoc analyses of the courses are carried out. In addition, selectivity analyses will be carried out for clinical subgroups (e.g. different ADHD profiles)",[57,58,59,28,60],"ADHD","Inattention","Hyperactivity","Executive Dysfunction",[62,57,63],"EEG-neurofeedback","children","2026-05-12",{"date":66,"type":36},"2026-05-19",{"date":68,"type":36},"2024-07-09",{"date":70,"type":22},"2026-12-31",{"name":72,"class":43},"Bielefeld University",2,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":94,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":44},"100636006","a-scalable-trans-diagnostic-intervention-targeting-adolescent-agency-supported-by-conversational-ai-agencia-100636006","NCT07560072","A Scalable Trans Diagnostic Intervention Targeting Adolescent Agency Supported by Conversational AI (AGENCIA)","A Randomized Controlled Trial Protocol of a Scalable Trans Diagnostic Intervention Targeting Adolescent Agency Supported by Conversational AI","AGENCIA","Inclusion Criteria:\n\n* Adolescents aged 12 to 18 years at enrollment.\n* Presence of emotional or behavioral difficulties causing functional interference (e.g., irritability, impulsivity, emotional dysregulation, conflicts at home or school, avoidance).\n* Difficulties compatible with neurodevelopmental profiles, regardless of formal diagnosis.\n* Ability to use digital materials through a personal device and basic reading skills in Spanish.\n* Availability to attend assessments and participate in the intervention and follow-up schedule.\n* Informed consent from caregivers and assent from the adolescent.\n\nExclusion Criteria:\n\n* Acute clinical risk at pre-screening or screening (e.g., imminent self-harm risk, severe agitation, aggression, disorganized behavior, or unsafe behaviors requiring immediate clinical care).\n* Score of \"Severe\" on any of the three HoNOSCA screening items (self-harm, substance-related problems, or bullying\u002Fsocial problems).\n* Uncompensated sensory, motor, or language barriers preventing valid completion of assessments or participation (e.g., severe visual or hearing impairment, significant receptive\u002Fexpressive language difficulties, motor limitations preventing device use).\n* Intellectual disability defined by screening tools: ABAS-II GAC ≤ 70 or Kaufman Brief Intelligence Test Composite Intelligence Quotient ≤ 70.\n* Any condition judged by the clinical team to require immediate alternative care or that would prevent safe participation.","12 Years","18 Years",{"count":85,"type":22},465,[25],"The aim of this clinical trial is to evaluate whether AGENCIA, a brief psychological program supported by digital technology and artificial intelligence, can help reduce emotional and behavioral difficulties in adolescents aged 12 to 18. These difficulties may include irritability, impulsive behaviors, conflicts at home or at school, or difficulties in managing intense emotions. The study also aims to determine whether the effects are similar across adolescents with different symptom profiles or neurodevelopmental characteristics.\n\nParticipants will be randomly assigned to one of three groups:\n\nAGENCIA Digital: a self-guided online version completed at home. AGENCIA in-person with a digital assistant: a clinician-delivered version supported by an interactive digital assistant to guide the exercises.\n\nDigital psychoeducation (control): a self-guided online program providing general information about adolescent well-being.\n\nThe main research questions are:\n\nDoes AGENCIA reduce overall emotional and behavioral difficulties? Does the program improve functioning, family accommodation, and personal agency (a young person's sense of being able to act and make changes)? Are the effects similar across adolescents with different profiles or neurodevelopmental characteristics?\n\nParticipants will:\n\n* Complete three structured sessions depending on their assigned group.\n* Complete brief online questionnaires at baseline (T0), immediately after the sessions (T1), and at 1-month (T2) and 6-month (T3) follow-ups.\n* Receive brief phone calls during follow-ups to support questionnaire completion.\n\nA total of 465 adolescents will take part in the study. Participation is voluntary and does not replace usual clinical care. The study does not involve medication or invasive procedures, and all digital tools operate within secure institutional systems.",[89,90,28,91,92,93],"Irritability","Neurodevelopmental Disorders","Emotional Dysregulation","Distress, Emotional","Distress, Psychological",[95,96,97,98,99,100,101,102],"Adolescents","Randomized controlled trial","Personal Agency","Digital health intervention","Neurodevelopmental disorders","Family accommodation","Conversational AI","Trans diagnostic interventions","NOT_YET_RECRUITING","2026-04-23",{"date":106,"type":36},"2026-04-30",{"date":108,"type":22},"2026-04-01",{"date":110,"type":22},"2028-12-31",{"name":112,"class":43},"Fundación Pública Andaluza para la gestión de la Investigación en Sevilla",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":4,"studyType":23,"phases":124,"briefSummary":126,"conditions":127,"keywords":130,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":44},"100488971","phase-1-frontal-itbs-for-impulsivity-and-suicidal-ideation-in-veterans-with-mild-traumatic-brain-injury-100488971","NCT05647044","Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury","Neuromodulation for Impulsivity and Suicidality in Veterans With Mild Traumatic Brain Injury and Common Co-occurring Mental Health Conditions","Inclusion Criteria:\n\n* 22-65 years of age\n* can read and speak English\n* meets criteria for mTBI according to the symptom attribution and classification (SACA) scale\n* Has a C-SSRS (suicidal ideation rating) of \\>1 within the past month\n* Has a history of impulsivity documented in the medical chart and\u002For a score of \\>20 on the UPPS-P negative urgency impulsivity subscale\n\nExclusion Criteria:\n\n* Has contraindications to iTBS (i.e., epilepsy)\n* Has contraindications to MRI (i.e., claustrophobia, ferromagnetic metal implants)\n* Has an active substance use disorder per the DSM-V criteria\n* Has a history of moderate to severe TBI\n* Has a history of non-traumatic neuroinjury (i.e., stroke, neurosurgery, hemorrhage)\n* Has a history of, or current psychosis not due to an external cause\n* Is pregnant\n* Has an active, unstable medical condition\n* Is within 12 weeks of a major surgery or operation\n* Is within 1 year of TBI","22 Years","65 Years",{"count":123,"type":22},55,[125],"PHASE1","The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI). These conditions have been shown to be linked. The investigators are using a high-powered magnetic pulse, called intermittent theta burst stimulation (iTBS) applied to the head to see if it can improve these symptoms. The high-powered magnetic pulse causes certain cells in the brain to activate, which seems to strengthen connections between parts of the brain. The purpose of this research is to gather early information on the safety and effectiveness of iTBS provided to the front of the head for impulsivity, SI and functional deficits after mTBI. The investigators plan to use the data collected in this study to develop larger studies in the future. iTBS is FDA approved, but not for these specific symptoms, or in the specific location the investigators are placing it. The investigators are testing to see if its effective for the above conditions when applied to the front of the head.",[128,129,28],"Mild Traumatic Brain Injury","Suicidal Ideation",[131,132,133,134,135,136,137,138,139,140,141,142],"brain concussion","brain injuries, traumatic","brain injuries","self-injurious behavior","suicide, attempted","suicide","impulsive behavior","risk-taking","brain diseases","craniocerebral trauma","social problems","mental disorders","2026-04-09",{"date":145,"type":36},"2026-04-14",{"date":147,"type":36},"2024-05-20",{"date":149,"type":22},"2028-03-31",{"name":151,"class":152},"VA Office of Research and Development","FED",{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":163,"phases":4,"briefSummary":164,"conditions":165,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":73},"100625371","interaction-between-atypical-work-schedules-andor-idel-time-at-work-on-at-risk-gambling-practices-100625371","NCT07421765","Interaction Between Atypical Work Schedules and\u002For Idel Time at Work on At-risk Gambling Practices","Evaluation de l'Interaction Entre Les Horaires Atypiques et\u002Fou Les Temps d'inactivité Sur Les Pratiques de Jeu à Risque Chez Les Adultes Travaillant Dans Ces Conditions","PRAT-JEU","Inclusion Criteria:\n\n* Living with current or remission gambling, as assessed using the Problem Gambling Index Scale (PGSI) score of ≥5\n* Having been employed during the current year\n* Patients with a personal mobile phone number and email address who agree to share them for research\n\nExclusion Criteria:\n\n* Patient in an exclusion period determined by another study\n* Patient who has expressed their opposition to participating in this research",{"count":162,"type":22},25,"OBSERVATIONAL","At-risk gambling causes individual and social harm, influenced by environmental, psychological, and socioeconomic factors. In France, 5% of adult gamblers show at-risk gambling practices. Atypical work schedules and idle time at work could increase this risk, but few studies have explored this. These working conditions impact the mental and cognitive health of workers, potentially contributing to at-risk gambling, especially during periods of idle time The study authors wish to explore the links between atypical work schedules, idle time at work, and at-risk gambling practices, considering social norms and individual vulnerabilities.",[166,167,168,169,28],"Gambling","Shift Work","Addictive Behavior","Boredom","2026-02-17",{"date":172,"type":36},"2026-02-19",{"date":174,"type":22},"2026-02-05",{"date":176,"type":22},"2027-02",{"name":178,"class":43},"Centre Hospitalier Universitaire de Nīmes",{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":17,"minAge":82,"maxAge":186,"enrollmentInfo":187,"targetDuration":4,"studyType":23,"phases":189,"briefSummary":190,"conditions":191,"keywords":194,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":44},"100623694","effects-of-cbt-i-on-impulsivity-and-risk-taking-in-youths-with-insomnia-100623694","NCT07399964","Effects of CBT-I on Impulsivity and Risk Taking in Youths With Insomnia","Effects of Cognitive Behavioural Therapy for Insomnia (CBT-I) on Impulsivity and Risk Taking in Youths With Insomnia: A Randomised Controlled Trial","Inclusion Criteria:\n\n* Chinese aged 12-24 years old\n* Written informed consent of participation in the study is given by the participant and his\u002Fher parent or guardian (for those aged under 18)\n* Willing to comply with the study protocol\n* Meeting the DSM-V diagnostic criteria of insomnia disorder and with a score on Insomnia Severity Index (ISI) \\>= 9 (suggested cut-off for adolescents)\n\nExclusion Criteria:\n\n* A current diagnosis of substance abuse or dependence; a current or past history of manic or hypomanic episode, schizophrenia spectrum disorders, neurodevelopmental disorders, organic mental disorders, or intellectual disabilities\n* Having a prominent medical condition known to interfere with sleep continuity and quality (e.g. eczema, gastro-oesophageal reflux disease)\n* Having a clinically diagnosed sleep disorder (other than insomnia disorder) that may potentially contribute to a disruption in sleep continuity and quality, such as narcolepsy, sleep-disordered breathing, and restless leg syndrome, as ascertained by the Structured Interview for Sleep Patterns and Disorders (DISP), a validated structured diagnostic interview to assess major sleep disorders according to the International Classification of Sleep Disorder (ICSD) criteria\n* Concurrent, regular use of medications(s) known to affect sleep continuity and quality including both western medications (e.g. hypnotics, steroids) and over-the-counter OTC medications (e.g. melatonin, Traditional Chinese Medicine, TCM)\n* In the opinion of the research clinician, having a clinically significant suicidality (presence of suicidal ideation with a plan or an attempt)\n* Currently receiving any psychological treatment for insomnia\n* With hearing or speech deficit\n* Night shift worker","24 Years",{"count":188,"type":22},124,[25],"Insomnia is prevalent in adolescents. Impulsive behaviours and excessive risk-taking have been linked to the manifestation of psychopathology in youths. Previous research based on behavioural and neurophysiological measures has found that individuals with insomnia demonstrated impaired inhibitory control, which is associated with detrimental outcomes such as substance abuse and self-harm.\n\nExisting evidence has shown some positive effects of cognitive behavioural therapy for insomnia (CBT-I) on insomnia symptoms and daytime functioning in youths. Given the link between insomnia and impulsivity reported in previous research, and sleep as a highly modifiable factor, we are conducting this randomised controlled trial to examine the impact of CBT-I in improving impulsivity and risk-taking in youth with insomnia.",[192,28,193],"Insomnia","Risk-Taking",[192,195,28,196],"Youth","Inhibitory Control",{"date":198,"type":36},"2026-02-10",{"date":200,"type":36},"2024-06-19",{"date":202,"type":22},"2026-12-01",{"name":204,"class":43},"The University of Hong Kong",{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":211,"eligibilityCriteria":212,"healthyVolunteers":213,"sex":17,"minAge":83,"maxAge":214,"enrollmentInfo":215,"targetDuration":4,"studyType":23,"phases":217,"briefSummary":218,"conditions":219,"keywords":221,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":227,"startDateStruct":229,"completionDateStruct":231,"leadSponsor":233,"locationsCount":44},"100353756","combined-anodal-transcranial-direct-current-stimulation-tdcs-and-cognitive-training-and-decision-making-100353756","NCT03886025","Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training and Decision-making","The Use of Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training to Modulate Decision-making in Healthy People","tDCS-CTDM","Inclusion Criteria:\n\n* Consenting volunteers aged between 18 and 40.\n\nExclusion Criteria:\n\n* Individuals with epilepsy, other neurological conditions and history of significant head injury will be excluded.\n* Individuals with a history of substance misuse, major mental disorder and those receiving psychotropic medication will be also excluded.",true,"40 Years",{"count":216,"type":22},60,[25],"This study aims to (i) assess the effects of combined tDCS and cognitive training on decision-making on a trained task (Iowa Gambling Task; IGT); and (ii) test generalization to a closely related cognitive domain, namely motor impulsivity. It is hypothesized that combined anodal tDCS and cognitive training will result in more advantageous decisions and better impulse control than combined sham tDCS and cognitive training.",[28,220],"Decision Making",[222,223,224,225],"transcranial Direct Current Stimulation (tDCS)","Decision-making","Implusivity","Brain stimulation","2025-08-04",{"date":228,"type":36},"2025-08-08",{"date":230,"type":36},"2022-09-15",{"date":232,"type":22},"2026-12-30",{"name":234,"class":43},"Dr. Najat Khalifa"]