[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"in-stent-coronary-artery-restenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:in-stent-coronary-artery-restenosis":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100623007","the-piccoleto-xi-a-prep-study-100623007",false,"NCT07391033","The PICCOLETO XI A-PREP Study","Impact of Lesion PREParation With Modifying Balloons During Drug-coated Balloon (DCB) Angioplasty for In-stent Restenosis (ISR) - PICCOLETO XI A-PREP Study","PICCOLETO-XI","Inclusion Criteria:\n\n* Adult patients ≥18 years of age\n* Patients who underwent DCB angioplasty for in-stent restenosis\n\nExclusion Criteria:\n\n\\- Lack of clinical outcome assessment","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","OBSERVATIONAL","To compare the angiographic and clinical outcomes of aggressive versus standard balloon preparation during drug-coated balloon (DCB) angioplasty for in-stent restenosis (ISR). The study will evaluate whether more aggressive lesion preparation with cutting\u002Fscoring\u002FOPN balloons improves outcomes compared to standard preparation with semi-compliant or non-compliant balloons.",[25,26],"In-Stent Coronary Artery Restenosis","Coronary Artery Disease",[28,29,30,31,32,33],"Drug-Coated Balloon","In-Stent Restenosis","Lesion Preparation","Cutting Balloon","Scoring Balloon","Percutaneous Coronary Intervention","NOT_YET_RECRUITING","2026-01-29",{"date":37,"type":38},"2026-02-05","ACTUAL",{"date":40,"type":21},"2026-06-01",{"date":42,"type":21},"2028-06-01",{"name":44,"class":45},"Fondazione Ricerca e Innovazione Cardiovascolare ETS","OTHER","In-stent Coronary Artery Restenosis"]