[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inactivity-physical\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inactivity-physical":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,76,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100625956","the-effects-of-one-day-of-activity-on-the-next-days-exercise-response-100625956",false,"NCT07429370","The Effects of One Day of Activity on the Next Day's Exercise Response","A Single Day of Inactivity on the Systemic Metabolic and Inflammatory Exercise Response","Inclusion Criteria:\n\n* • between the ages of 18-30 years old\n\nExclusion Criteria:\n\n* • free from acute or chronic illness (cardiac, pulmonary, liver, or kidney abnormalities, cancer, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other known metabolic disorders)\n\n  * do not take medications related to metabolism (i.e., statins, metformin, GLP-1 agonists)\n  * free from orthopedic limitations (including any artificial joints)\n  * currently smoke or participate in other forms of tobacco use.",true,"ALL","18 Years","30 Years",{"count":21,"type":22},6,"ESTIMATED","INTERVENTIONAL",[25],"NA","Exercise can reduce the risk of several chronic diseases. However, recent studies have suggested sitting for too long before exercising can decrease exercise benefits. This study will help determine why this may occur.",[28],"Inactivity, Physical",[30,31],"Exercise","Metabolism","RECRUITING","2026-02-20",{"date":35,"type":36},"2026-02-24","ACTUAL",{"date":38,"type":36},"2026-01-01",{"date":40,"type":22},"2026-12-31",{"name":42,"class":43},"Concordia University Wisconsin","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":44},"100581286","improving-physical-activity-participation-in-latinas-with-mindfulness-100581286","NCT06848335","Improving Physical Activity Participation in Latinas With Mindfulness","Seamos Activas","Inclusion Criteria:\n\n* Female\n* Generally healthy (If asthma, controlled high blood pressure and\u002For controlled type II diabetes, may be able to participate with physician consent)\n* Sedentary (defined as participating in MVPA for 60 minutes or less per week and engaging in muscle-strengthening exercise on less than 2 days per week)\n* Hispanic or Latina (self-identified)\n* Must be able to read and write in Spanish fluently\n* 18 - 65 years of age\n* Planning on living in the area for the next 18 months\n* Own a cell phone capable of sending and receiving text messages\n* Required to have reliable access to the Internet via a computer or mobile device\n* Must be able to receive materials in the mail, either at your own home or at a mailbox\n\nExclusion Criteria:\n\n* BMI greater than 45\n* Not able to walk continuously for 30 minutes\u002Flimited ability to complete daily activity or ability to exercise\n* Exercise is against advice of doctor\n* Inability to walk independently\n* Current or planned pregnancy in the next 12 months\n* Heart disease\u002Ftreatment\n* Heart murmur\n* Angina\u002Fchest pain or Angina\u002Fchest pain with exertion\n* Palpitations\n* Stroke\u002FTransient Ischemic Attacks\n* Peripheral Vascular Disease\n* Diabetes that requires insulin\n* Non-insulin dependent diabetes without physician approval to participate\n* Chronic infectious disease- HIV, Hepatitis C but does not have doctor approval\n* Chronic liver disease\n* Cystic Fibrosis\n* Abnormal EKG on last EKG performed\n* Emphysema, Chronic bronchitis, Chronic Obstructive Pulmonary Disease\n* Seizure in past year\n* Surgery in past year on heart, lung, joint, orthopedic surgery\n* Surgery pending in next year on lung, joint, orthopedic surgery\n* Unusual\u002Fconcerning shortness of breath\n* Asthma (may be able to participate with physician consent)\n* High blood pressure\u002Fhigh blood pressure medication (may be able to participate with physician consent)\n* Use of Beta Blockers or medicines not approved by doctor.\n* Abnormal Medical Stress Test in the last 12 months\n* Musculoskeletal problems\n* Fainting\u002Fdizziness more than 3 times in past year OR which interferes with daily activities OR causes loss of balance\n* Cancer treatment in past 3 months\n* Hospitalized for psychiatric disorder in past 3 years or suicidal\n* Participation in prior Seamos Activas II study or participant in other research study about exercise currently or within the last 6 months ago","FEMALE","65 Years",{"count":55,"type":22},258,[25],"In this study, the investigators are exploring how a mindfulness-based physical activity program can help improve exercise habits and overall health among 258 inactive Latina women aged 18 to 65. The study will be conducted entirely remotely over and 18 month period. During the first 6 months, all participants will receive an exercise program that has previously been tested by our research team. After 6 months, the investigators will check if participants are meeting the recommended exercise guidelines of at least 150 minutes\u002Fweek of at least moderate intensity activity. Participants who meet the guidelines will continue with the successful exercise program for another 6 months. For participants who do not meet the guidelines (are exercising less than 150 minutes\u002Fweek), they will receive one of two enhanced programs, which will be randomly assigned. One program offers additional physical activity support, and the other incorporates stress management through mindfulness techniques. For all participants, over 18 months, the investigators will track physical activity levels, stress, and heart health indicators.",[59,60,28],"Inactivity","Inactivity\u002FLow Levels of Exercise",[62,63,64,65,30,66],"Physical Activity","Latinas","Spanish-Language","Text-Message","Mindfulness","2025-04-23",{"date":69,"type":36},"2025-04-25",{"date":71,"type":36},"2025-03-21",{"date":73,"type":22},"2029-07-31",{"name":75,"class":43},"Bess Marcus",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":16,"sex":17,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":88,"phases":4,"briefSummary":89,"conditions":90,"keywords":97,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":109,"leadSponsor":111,"locationsCount":44},"100573300","oral-breath-test-to-measure-anabolic-sensitivity-to-a-protein-meal-across-the-age-and-physical-activity-spectrum-100573300","NCT06744491","Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum","Anabolic Sensitivity Across the Lifespan","NFRF","Inclusion Criteria:\n\n* Healthy will be defined as screened by the PAR-Q+ (The Physical Activity Readiness Questionnaire for everyone)\n* Chronological age for Healthy Young (age: 18-35 years) or Older (age: 60-80 years) adults\n* Chronological age between 8 to 16 years, with maturity offset \\\u003C -1 year from age of Peak Height Velocity (aPHV) for children and between -0.5 to +1.5 years from aPHV in adolescent participants\n* BMI between normal to overweight (18.5 - 29.9 kg\u002Fm2)\n\nExclusion Criteria:\n\n* Regular use of nonsteroidal anti-inflammatory dugs (with the exception of daily low-dose aspirin)\n* use of anticoagulants\n* use of a walker, cane, or assistive walking device\n* infectious or gastrointestinal disease\n* inability to comply with study protocol (e.g., unable to track diet)\n* regular tobacco use\n* self-reported illicit drug use (e.g., growth hormone, testosterone, etc.)\n* diagnosed chronic illness (e.g., type 2 diabetes, heart disease, thyroid disease)\n* pregnant\n* hormonal replacement therapy","8 Years","80 Years",{"count":87,"type":22},80,"OBSERVATIONAL","The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.",[28,91,92,93,94,95,96,62],"Aging","Healthy Aging","Growth & Development","Sex Differences","Anabolic Sensitivity","Protein Metabolism",[98,99,100,101,102,103],"anabolic sensitivity","aging","growth and development","physical activity","skeletal muscle","stable isotopes","NOT_YET_RECRUITING","2024-12-16",{"date":107,"type":36},"2024-12-20",{"date":107,"type":22},{"date":110,"type":22},"2025-08-31",{"name":112,"class":43},"University of Toronto",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":85,"enrollmentInfo":121,"targetDuration":4,"studyType":23,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":44},"100548734","effects-of-a-lifestyle-and-sleep-intervention-in-non-exercising-adults-100548734","NCT06424847","Effects of a Lifestyle and Sleep Intervention in Non-exercising Adults","Effects of a Lifestyle and Sleep Intervention Program on Quality of Life and Physical Activity Levels in Non-exercising Adults, SPIRAL+ Randomized Controlled Trial","SPIRAL+","Inclusion Criteria:\n\n* Participant who is physically inactive (i.e. less than 150 minutes of moderate intensity physical activity per week)\n* Participant aged 18 to 80 years old\n* Participant able to provide written informed consent\n* Participant able to participate in regular physical activity (no medical contraindication to exercise)\n* Participant affiliated to social security or a similar regimen\n\nExclusion Criteria:\n\n* Any condition that in the opinion of the responsible physician or investigator makes the potential participant unsuitable for the study\n* A participant who scores 11111 on the EQ-5D-5L questionnaire\n* A diagnosed and treated sleep disturbance (sleep apnea, insomnia, restless legs syndrome)\n* Persons concerned by articles L1121-5, L1121-6 and L1121-8 of the public health code (i.e. pregnancy, person deprived of liberty or subject to a legal protection measure, vulnerable person or legally protected adult)\n* Person already included in another interventional study",{"count":122,"type":22},201,[25],"Background. Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on quality of life. Recent studies suggest that a lifestyle intervention might have a role in the reduction of CDV risk. Lifestyle intervention programs typically combine physical activity, diet and behavior modification components. Poor sleep health is highly prevalent in the general population and contributes to increased risk of several noncommunicable diseases. However, sleep is rarely addressed in lifestyle intervention programs in primary prevention. Given the high prevalence of poor sleep health in people without a diagnosed sleep disorder, and the associated health consequences, there is a clear need for broad-reaching, effective interventions to improve sleep quality in subclinical populations.\n\nAims. The main objective of this study is to compare a lifestyle intervention program including a sleep intervention compared to a lifestyle intervention program alone on the health-related quality of life (measured by the EQ-5D-5L) and physical activity levels of non-exercising adults.\n\nMethods. Non-exercising adults (n=201) will be recruited in the community via advertisement or their primary care doctor and then randomized to one of the following 3 groups : lifestyle intervention, lifestyle and sleep intervention or standard care. The lifestyle intervention includes a physical activity component (physical activity initiation visit and 6 months of supervised physical activity, once weekly), a diet component (consultation with a dietician and 3 group sessions). The sleep intervention includes individualized face-to-face sessions aimed at improving and optimizing sleep hygiene.\n\nAt baseline and after 6 and 12 months, quality of life, physical activity levels, cardiovascular and metabolic risk factors will be evaluated.\n\nPerspectives. This study should determine whether adding a sleep intervention dimension to a lifestyle intervention program provides significant benefits in terms of quality of life and physical activity levels. Based on this study, the modalities of real-life lifestyle intervention programs could be reconsidered in order to provide optimal primary prevention.",[28,126],"Lifestyle Risk Reduction",[128,129,101,130],"lifestyle intervention","sleep intervention","behavior change techniques","2024-05-24",{"date":133,"type":36},"2024-05-28",{"date":135,"type":36},"2024-05-02",{"date":137,"type":22},"2028-05-01",{"name":139,"class":43},"University Hospital, Grenoble"]