[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"incentive-spirometer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:incentive-spirometer":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100606722","effect-of-breathing-training-on-symptoms-of-gastroesophageal-reflux-disease-100606722",false,"NCT07179250","Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease","Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease: A Parallel Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 20 to 80 years\n* Endoscopic finding of reflux esophagitis (LA grade A) with proton pump inhibitor (PPI) use \\> 2 months, or 24-hour pH monitoring showing acid exposure time (AET) \\> 6%, or endoscopic diagnosis of reflux esophagitis LA grade B or higher\n* Willingness to comply with the full training and follow-up protocol\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women\n* History of anti-reflux surgery\n* Severe cardiopulmonary dysfunction or respiratory disease\n* Inability to perform the training exercises or attend follow-up visits","ALL","20 Years","80 Years",{"count":20,"type":21},51,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate whether two types of breathing training can improve symptoms of gastroesophageal reflux disease (GERD) in adults.\n\nThe main research questions are:\n\n* Do volume-oriented incentive spirometry (VIS) or diaphragmatic breathing exercise (DBE) improve GERD symptoms compared with usual care?\n* Do these breathing exercises reduce the symptoms of GERD?\n* Does volume-oriented incentive spirometry (VIS) produce greater improvement in GERD symptoms compared with DBE?\n* Do these exercises increase the strength of the lower esophageal sphincter (LES)?\n\nResearchers will compare VIS training, DBE training, and usual care to determine whether breathing training can serve as a safe and effective non-pharmacological treatment option for GERD.\n\nParticipants will:\n\n* Be randomly assigned to VIS training, DBE training, or usual care\n* Perform their assigned breathing training (if in the intervention group) twice daily for 6 weeks\n* Attend study visits at baseline and at week 7 for questionnaires and esophageal function tests\n* Keep a diary of their symptoms and breathing practice",[27,28,29,30],"Incentive Spirometer","Diaphragmatic Breathing","Gastroesophageal Reflux Disease (GERD)","Breath Exercise",[32,33,34,28,35,27,36,37,38,39],"GERD","Gastroesophageal Reflux Disease","Acid Reflux","Breathing Training","Volume-Oriented Incentive Spirometry","GERDQ","Gastroesophageal Reflux Disease Questionnaire","breath exercise","NOT_YET_RECRUITING","2025-09-23",{"date":43,"type":44},"2025-09-26","ACTUAL",{"date":46,"type":21},"2025-09",{"date":48,"type":21},"2026-05",{"name":50,"class":51},"Changhua Christian Hospital","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100601608","effect-of-incentive-respiratory-training-on-pulmonary-functions-and-functional-capacity-in-children-with-b-thalassemia-major-100601608","NCT07112703","Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major","Inclusion Criteria:\n\n1. Diagnosed as thalassemia \\& subjected to blood transfusion\n2. Their age range from 6 to 10 years old\n3. Both sexes, male and female, will participate.\n4. Subjects are able to follow simple verbal commands or instructions included in the procedures.\n\nExclusion Criteria:\n\n1. Children with mental retardation or any other disability .\n2. Children with visual or hearing defects.\n3. Children with cardiovascular, chest pulmonary, and heart diseases.\n4. Children with any postoperative cardiovascular, chest pulmonary, and heart conditions.","6 Years","10 Years",{"count":61,"type":21},50,[24],"The study was done to:\n\n1. Investigate the effect of respiratory training on functional lung capacity and\n2. To detect the effect of respiratory training on pulmonary functions in children with β-thalassemia major.\n3. To detect the level of oxygen saturation and heart rate during and after blood transfusion in children with β-thalassemia major.",[27,65,66,67,68],"Pulmonary Function","Functional Capacity","Child, Only","Thalassemia Major","RECRUITING","2025-08-02",{"date":72,"type":44},"2025-08-08",{"date":74,"type":44},"2025-04-07",{"date":76,"type":21},"2025-10-08",{"name":78,"class":51},"Rawan Mohammed Khairy Mostafa Elsawy",1]