[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"incontinence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:incontinence":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,43,75,97,128,160,183,207,232,254],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100521693","continence-sexual-function-fitness-and-the-health-of-men-after-surgery-for-prostate-cancer-100521693",false,"NCT06072911","Continence, Sexual Function, Fitness and the Health of Men After Surgery for Prostate Cancer","Continence, Sexual and Metabolic Health Programming to Promote Prostate Cancer Wellness for Life (CONTROL4LIFE)","CONTROL4LIFE","Inclusion Criteria:\n\n* have a diagnosis of prostate cancer (stage I to IV);\n* be scheduled for a prostatectomy surgery (any surgical approach);\n* have no restriction to participate in at least mild levels of physical activity, as confirmed by the Physical Activity Readiness Questionnaire (PAR-Q+);\n* speak and understand English.\n* adult: 18 years of age or older\n* optional exercise component: willing and able to commit to the 12-week intervention\n\nExclusion Criteria:\n\n* have any medical conditions that may interfere with continence (i.e. neurological diseases);\n* have any contraindications to exercise testing or training;\n* have recent (\\>6 months) modifications to any medication aiming to reduce urinary incontinence (i.e. Myrbetric);\n* do not have regular access to the internet and a smart device or a computer at home\u002F at their community center;\n* are already receiving a pelvic floor exercise program through a pelvic floor physical therapist from their community.","MALE","18 Years",{"count":20,"type":21},106,"ESTIMATED","INTERVENTIONAL",[24],"NA","The Continence, Sexual and Metabolic Health (CONTROL 4 LIFE) study will evaluate the recovery of continence, sexual function, and health outcomes in individuals who have undergone surgery for prostate cancer. The purpose of this study is to better understand the timelines of recovery for these outcomes after surgery for prostate cancer. As part of this study, all participants will receive resources offered by Alberta Health Services regarding pre- and post-prostatectomy care, including information on pelvic floor exercises. Through the CONTROL 4 LIFE study, the investigators will also be evaluating outcomes related to physical activity, fitness and quality of life. These assessments will enable the investigators to better understand how well and how long it takes for individuals to recover after surgery for prostate cancer.",[27,28,29],"Prostate Cancer","Incontinence","Metabolic Disease","RECRUITING","2026-05-28",{"date":33,"type":34},"2026-05-29","ACTUAL",{"date":36,"type":34},"2024-02-27",{"date":38,"type":21},"2026-06-30",{"name":40,"class":41},"University of Alberta","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100467095","phase-4-treating-incontinence-for-underlying-mental-and-physical-health-100467095","NCT05362292","TReating Incontinence for Underlying Mental and Physical Health","Cognitive, Urinary, and Functional Trajectories of Older Women Using Pharmacologic Treatment Strategies for Urgency Incontinence","TRIUMPH","Inclusion Criteria:\n\n* Aged 60 years or older at the time of enrollment\n* Female sex at birth, without surgical or hormonal gender re-assignment therapy\n* Able to walk to the bathroom and use the toilet without assistance\n* Report urinary incontinence starting at least 3 months prior to screening\n* Report that at least half of incontinence episodes occur with a sudden or strong sensation of urgency\n* Report 2 or more urgency incontinence episodes over a 7-day period\n* Willing to provide informed consent and adhere to study procedures throughout the length of the study\n\nExclusion Criteria:\n\n* Prior clinician diagnosis of dementia, or a Montreal Cognitive Assessment (MOCA) score of 17 or lower on screening cognitive evaluation\n* Current use of anticholinergic, beta-3-adrenergic agonist, or other medication designed to improve urgency incontinence symptoms, or use in the past 1 month\n* Initiation, discontinuation, or dose change of dementia medications (such as donepezil, galantamine, memantine, rivastigmine) in the past 1 month (but candidates on stable doses are eligible)\n* Initiation, discontinuation, or dose change of other drugs with strong anticholinergic effects (based on the Beers List) in the past 1 month (but candidates on stable doses are eligible)\n* Initiation, discontinuation, or dose change of other drugs that can affect urinary frequency, including diuretics, in the past 1 month (but candidates on stable doses are eligible)\n* Current urinary tract infection (UTI) based on screening urinalysis and culture (but candidates can re-present for re-screening after undergoing treatment for UTI)\n* History of allergy or sensitivity to either of the study medications or an ingredient in the placebo or study medication capsule\n* Severe hepatic impairment (Child-Pugh score B or greater) or renal impairment (creatinine clearance \\\u003C30 mL\u002Fmin) as a contraindication to both study medications\n* Current bladder obstruction or urinary retention (defined by symptoms suggesting difficulty emptying the bladder in addition to postvoid residual urine volume greater than 150 cc by portable bladder ultrasound)\n* Uncontrolled hypertension (based on measured systolic blood pressure greater than 180 or diastolic blood pressure greater than 110 mmHg) as a contraindication to beta-3-adrenergic therapy\n* Self-reported history of gastric retention, uncontrolled narrow angle glaucoma, myasthenia gravis, severe ulcerative colitis, or toxic megacolon as contraindications for anticholinergic bladder therapy\n* Use of drugs with adverse interactions with one of the study medications in the past 1 month, including potent CYP3A4 inhibitors, hepatic enzyme metabolism inducers, narrow therapeutic index drugs metabolized by CYP2D6, or intention to start taking one of these medications during the study treatment period\n* History of bladder surgery, invasive intra-vesical therapy, or bulk bladder injections in the past 3 months (more remote surgery will not be exclusionary), or intention to undergo one of these procedures in the study treatment period\n* Use of other specialized incontinence therapy (electrostimulation, pelvic physiotherapy, formal behavioral therapy overseen by certified practitioners) in the past 3 months (more remote therapy will not be exclusionary), or intention to undergo one of these procedures in the study treatment period\n* Inability to sign informed consent or complete questionnaires, interviews, or study testing in English\n* Other condition that would prevent the participant from completing study procedures, in the opinion of the investigators (e.g., uncontrolled psychosis)",true,"FEMALE","60 Years",{"count":55,"type":21},270,[57],"PHASE4","The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes in ambulatory older women with urgency-predominant urinary incontinence and either normal or mildly impaired cognitive function at baseline.",[60,61,62,63,64,28],"Urinary Incontinence, Urge","Urinary Incontinence","Overactive Bladder","Incontinence, Urge","Incontinence, Urinary","2026-03-04",{"date":67,"type":34},"2026-03-06",{"date":69,"type":34},"2022-10-04",{"date":71,"type":21},"2027-08-02",{"name":73,"class":41},"University of California, San Francisco",2,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":51,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":42},"100568315","a-telehealth-intervention-to-increase-patient-preparedness-for-surgery-in-latinas-100568315","NCT06679621","A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas","TIPPS-Urogyn","Inclusion Criteria:\n\nPatients who\n\n* Self-report as female\n* 18 years and older\n* Self-report as Hispanic ethnicity\n* Scheduled to undergo a surgery for a urogynecologic condition in the operating room (surgery to correct pelvic organ prolapse, urinary\u002Ffecal incontinence, fistula, urethral masses)\n* Able to read and write English and\u002For Spanish\n\nUrogynecologists who -Routinely perform urogynecologist surgeries to correct pelvic organ prolapse, urinary\u002Ffecal incontinence, fistula, urethral masses\n\nNurses who\n\n* Spend most of their time at a urogynecologic clinic\n* Engage in the process of preparing patients for urogynecologic surgery\n\nExclusion Criteria:\n\nPatients who\n\n* Self-report as male\n* Are less than 18 years of age\n* Self-report as not of Hispanic ethnicity\n* Scheduled to undergo a surgery for a condition that is not urogynecologic or is not in the operating room\n* Patients undergoing procedures that are traditionally performed in the office (bladder Botox, pelvic floor Botox, urethral bulking)\n\nUrogynecologists who\n\n-Do not routinely perform urogynecologic surgery\n\nNurses who\n\n* Do not spend most of their time at a urogynecology clinic\n* Do not engage in the process of preparing patients for urogynecologic surgery",{"count":83,"type":21},357,[24],"There are 3 aims of this study. In Aim 1 community patient partners will be enrolled to help guide the research being performed in all of the aims. Investigators will also administer a survey that will help determine factors associated with surgical preparedness. In Aim 2 investigators will develop an intervention to increase surgical preparedness using Human Centered Design Methods. Aim 3 will pilot test the intervention using mixed methods to determine feasibility and implementation outcomes.",[28,87],"Prolapse","2025-07-21",{"date":90,"type":34},"2025-07-24",{"date":92,"type":34},"2024-11-11",{"date":94,"type":21},"2027-06-01",{"name":96,"class":41},"University of Alabama at Birmingham",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":22,"phases":107,"briefSummary":108,"conditions":109,"keywords":112,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100599429","relax--feel-at-ease-release-100599429","NCT07084376","RElax & feeL at EASE (RELEASE)","A Multicenter, Parallel-group, Randomized Controlled Trial to Assess the Efficacy of Two Different Educational Approaches on Intermittent Catheter-related Acceptance and Patient-Reported Outcome Measures (PROMs): RElax & feeL at EASE (RELEASE)","RELEASE","Inclusion Criteria:\n\n* Male patients aged 18 years or older.\n* Diagnosed with neurogenic bladder requiring self-managed intermittent catheterization (IC).\n* Currently performing IC or newly prescribed IC.\n* Able to provide informed consent and understand study instructions.\n* Able to understand and complete study questionnaires in Italian.\n\nExclusion Criteria:\n\n* Presence of cognitive impairment limiting ability to understand or perform IC independently.\n* Severe upper limb motor deficits preventing independent catheterization.\n* Active urinary tract infection at baseline.\n* Participation in another interventional study that could interfere with outcomes.\n* Any condition that, in the opinion of the investigators, makes the patient unsuitable for study participation.",{"count":106,"type":21},64,[24],"This multicenter, parallel-group, randomized controlled trial (RELEASE) aims to evaluate the efficacy of two educational approaches on acceptance and adherence to intermittent catheterization (IC) among adult male patients. Participants requiring IC training will be randomized to either an enhanced educational intervention (informational booklet, video tutorial, and standard training) or standard clinical practice training alone. The primary outcome is the change in Intermittent Catheterization Acceptance Test (I-CAT) scores over three months. Secondary outcomes include adherence (I-CAS), urinary symptoms (USQNB-IC), patient autonomy, satisfaction with assistive technology (QUEST), and functional abilities. The study seeks to identify the most effective educational strategy to improve psychological acceptance, promote adherence, and reduce complications in patients performing IC, ultimately supporting patient-centered care and health system efficiency.",[28,110,111],"Neurogenic Bladder Dysfunction","Urinary Retention",[113,114,115,116,117,118],"Intermittent catheterization","Self-catheterization","Patient education","Adherence","Acceptance","Male urology","NOT_YET_RECRUITING","2025-07-17",{"date":90,"type":34},{"date":123,"type":21},"2025-09-01",{"date":125,"type":21},"2026-09-30",{"name":127,"class":41},"Stefania Musco",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":136,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":139,"conditions":140,"keywords":147,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":74},"100579306","pelvic-health-rehabilitation-after-breast-and-gynecologic-cancer-100579306","NCT06822582","Pelvic Health Rehabilitation After Breast and Gynecologic Cancer","A Pelvic Health eModule to Address Urogenital Impairments After Breast and Gynecologic Cancer: a Pilot Prospective Interventional Study","GYVE","Inclusion Criteria:\n\n* be \\>18 years of age;\n* have received a diagnosis of breast or gynecological (endometrial, cervical, ovarian, vulvar or vaginal) cancer (Stage I-IV) ;\n* be on active cancer treatment or have completed any cancer treatment (surgery and\u002For radiation therapy and\u002For chemotherapy) within the last 3 years;\n* be able to provide informed written consent in English or French;\n* have a urogenital dysfunction, as screened by a score of ≥ 2 on the Pelvic Floor Bother Questionnaire.\n\nExclusion Criteria:\n\n* do not have regular access to internet, to a smart device or a computer, at home.",{"count":137,"type":21},20,[24],"The GYVE study aims at testing an online program (eModule) to help people who have had breast or gynecologic cancer and are experiencing pelvic health issues like urinary incontinence and pain during sex. These cancers and their treatments can cause significant pelvic health problems, affecting daily life and quality of life. Physiotherapy can help, but access is often limited due to costs and other barriers. The study will involve 20 participants from Quebec and Edmonton, who will take part in a 12-week program with weekly online group sessions led by a physiotherapist. Topics include pelvic floor muscle training, use of vaginal moisturizers, hydration, diet, and pain management. Led by experts in cancer rehabilitation and pelvic health, the study aims to provide valuable information on the feasibility and effectiveness of the eModule, potentially leading to broader implementation to help more people with lived experience of cancer.",[141,142,28,143,144,145,146],"Gynecologic Cancers","Breast Cancer Female","Incontinence Bowel","Sexual Dysfunction","Vaginal Atrophy, Sexual Dysfunction, Vaginal Dryness, Dyspareunia","Constipation",[148,149,150],"pelvic health","telerehabilitation","supportive cancer care","2025-02-11",{"date":153,"type":34},"2025-02-12",{"date":155,"type":34},"2025-01-07",{"date":157,"type":21},"2026-06",{"name":159,"class":41},"Laval University",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":168,"targetDuration":4,"studyType":170,"phases":4,"briefSummary":171,"conditions":172,"keywords":4,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":4},"100572960","bladder-wall-thickness-in-symptomatic-urinary-stress-incontinence-and-its-correlation-with-urodynamics-results-100572960","NCT06740058","Bladder Wall Thickness in Symptomatic Urinary Stress Incontinence and Its Correlation with Urodynamics Results","Bladder Wall Thickness in Symptomatic Urinary Stress Incontinence and Its Correlation with Urodynamics Results. a Retrospective and Prospective Observational Study","BWT-IUS","Inclusion Criteria:\n\n1. Participant is willing and able to give informed consent for participation in the study.\n2. Women aged \\> 18 y.o.\n3. Women symptomatic for pure or predominant stress incontinence attending the urogynecology outpatient clinic at our institution.\n4. Patients undergoing urogynecological standard evaluation for their symptoms, including outpatient gynecological visit and a transvaginal ultrasound.\n5. Patients undergoing invasive urodynamic examination for objective assessment of their symptoms or in preparation for possible anti-incontinence surgery.\n\nExclusion Criteria:\n\n1. Patients with pure or predominant OAB symptomatology\n2. Current use of antimuscarinic agents or beta3-agonists (for example Mirabegron)\n3. Presence of urological or gynecological cancer.\n4. Patients with previous anti-incontinence surgery.\n5. Patients with pelvic organ prolapse \\> II stage.\n6. Patients with chronic bladder retention.\n7. Patients with neurological diseases that may affect bladder function and urodynamic results.\n8. Participants unwilling or unable to give informed consent for participation in the study.",{"count":169,"type":21},60,"OBSERVATIONAL","This clinical study aims to assess the utility of ultrasonographic bladder wall thickness (BWT) measurement in patients suffering from symptomatic stress urinary incontinence (SUI). SUI is a condition characterized by involuntary leakage of urine during activities that increase intra-abdominal pressure and represents a very frequent disorder impacting women's quality of life. To diagnose SUI more accurately and especially before surgical treatment, patients undergo invasive urodynamic examination. This examination allows us to objectify the presence of any bladder dysfunction and, in particular, to evaluate the presence of detrusor overactivity. Detrusor overactivity is defined as any occurrence of detrusor contraction(s) during filing cystometry. These contractions, which may be spontaneous or provoked, produce a waveform on the cystogram, of variable duration and amplitude and may cause or not urgency symptoms. In absence of any urodynamic detrusor overactivity, the patient may be diagnosed with pure SUI. This is essential to assess before surgical treatment to avoid worsening of symptoms and to decide whether to treat the patient with concomitant pharmacological treatment. On the contrary, ultrasonography offers a non-invasive and accessible approach to evaluate bladder function. This study will involve a cohort of patients with SUI, who will undergo ultrasonographic assessment of BWT and preoperative urodynamic assessment. The objective is to determine whether BWT correlates with the urodynamics results and whether it can predict the presence or absence of detrusor overactivity and confirm the pure stress urinary incontinence",[173,28],"Urinary Incontinence , Stress","2024-12-17",{"date":176,"type":34},"2024-12-18",{"date":178,"type":21},"2025-01",{"date":180,"type":21},"2026-02",{"name":182,"class":41},"IRCCS San Raffaele",{"id":184,"slug":185,"hasResults":11,"nctId":186,"briefTitle":187,"officialTitle":188,"acronym":4,"eligibilityCriteria":189,"healthyVolunteers":11,"sex":52,"minAge":190,"maxAge":4,"enrollmentInfo":191,"targetDuration":4,"studyType":22,"phases":192,"briefSummary":193,"conditions":194,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":42},"100563233","effectiveness-of-the-ai-supporter-in-reducing-urinary-tract-infections-100563233","NCT06613503","Effectiveness of the AI-Supporter in Reducing Urinary Tract Infections","Testing the Effectiveness of the AI-Supporter in Reducing Urinary Tract Infections, Incontinence-associated Dermatitis and Caregiving Costs for Incontinence Patients","Inclusion Criteria:\n\n* Participants must have been bedridden for at least 3 months and have urinary and\u002For fecal incontinence.\n* Female participants aged over 20 years old.\n* Participants must be capable of wearing the AI-supporter device during the study period.\n\nExclusion Criteria:\n\n* Participants with severe skin conditions unrelated to incontinence.\n* Participants with current urinary tract infections or incontinence-associated dermatitis at the time of enrollment.\n* Participants who are unable to provide informed consent or have a legal representative to do so.","20 Years",{"count":169,"type":21},[24],"The \"AI Supporter,\" an intelligent excretion management robot, leverages artificial intelligence-based vision recognition to autonomously detect and cleanse affected areas, followed by drying and changing the diaper, thereby reducing caregiver strain and enhancing care quality. This study aims to assess the efficacy of the \"AI Supporter\" in decreasing the incidence of urinary tract infections and incontinence-associated dermatitis among incontinent patients, in addition to exploring its cost-effectiveness.\n\nAdopting an experimental (two groups) and longitudinal design, this research utilizes both convenience and random sampling strategies. The study anticipates recruiting 60 female subjects who have been confined to bed for more than three months with urinary and\u002For fecal incontinence. Participants will intermittently use the AI Supporter over a 14-day period. Measurement tools include routine urine analysis.",[28,195,196,197],"Urinary Tract Infection","Incontinence-associated Dermatitis","Cost-effectiveness","2024-09-23",{"date":200,"type":34},"2024-09-26",{"date":202,"type":34},"2024-07-22",{"date":204,"type":21},"2025-10-31",{"name":206,"class":41},"China Medical University Hospital",{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":212,"acronym":213,"eligibilityCriteria":214,"healthyVolunteers":11,"sex":215,"minAge":18,"maxAge":4,"enrollmentInfo":216,"targetDuration":218,"studyType":170,"phases":4,"briefSummary":219,"conditions":220,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":42},"100371012","quality-of-life-after-conservative-and-surgical-treatment-of-pelvic-organ-prolapse-100371012","NCT04110821","Quality of Life After Conservative and Surgical Treatment of Pelvic Organ Prolapse","Quality of Life After Conservative and Surgical Treatment of Pelvic Organ","LOLIPOP","Inclusion Criteria:\n\n\\- Pelvic Organ Prolapse (POP)\n\nExclusion Criteria:\n\n* \\\u003C 18 years\n* Patients unable to understand an informed consent\n* Patients unwilling to participate\n* emergency operations\n* pregnancy\n* Overactive Bladder without descensus\n* Stool incontinence without POP","ALL",{"count":217,"type":21},134,"5 Years","This is an observational study that gives baseline and follow-up information, that does not directly influence the allocation of patients to various treatment Options (conservative and surgical therapy of Pelvic Organ Prolapse) but the knowledge gained of the data will help to develop treatment strategies.",[221,222,28],"Pelvic Organ Prolapse","Quality of Life","2024-07-29",{"date":225,"type":34},"2024-07-30",{"date":227,"type":34},"2019-09-15",{"date":229,"type":21},"2028-12",{"name":231,"class":41},"University Hospital, Basel, Switzerland",{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":239,"targetDuration":4,"studyType":22,"phases":241,"briefSummary":242,"conditions":243,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":42},"100531529","penile-vibratory-stimulation-in-the-prevention-of-sexual-dysfunction-and-urinary-incontinence-after-radical-prostatectomy-100531529","NCT06200987","Penile Vibratory Stimulation in the Prevention of Sexual Dysfunction and Urinary Incontinence After Radical Prostatectomy","Planned Penile Vibratory Stimulation in the Prevention of Sexual Dysfunction and Urinary Incontinence After Radical Prostatectomy: a Randomized Controlled Study","Inclusion Criteria:\n\n* Men who are undergoing nerve-sparing radical prostatectomy\n* Pre operative erectile function of IIEF-EF \\> 25\n* Sexually active . Continent before surgery defined as a score of 0 on the ICIQ-SF questionnaire\n\nExclusion Criteria:\n\n* Urinary incontinent before surgery\n* Comorbidity that prevents the patient from taking PDE5-inhibitors\n* Disease in the penis or in the penile skin (Peyronies, phimosis)\n* Problems using the vibrator ie impaired function of the hands",{"count":240,"type":21},100,[24],"To investigate if post-operative penile vibration stimulation kan be used to reduce or prevent sexual dysfunction and urinary incontinence after radical prostatectomy. This will be done in a randomized, controlled, non-blinded study. Men that undergo nerve preserving surgery for prostate cancer is allocated into an intervention group and a control group. A total of 100 men will be included for a power of 80%. The intervention group will be instructed to use the \"Ferticare 2.0\" vibrator for at least five minutes a day with an amplitude of 1 mm and frequency of 90 Hz (these settings were found in a pilot study) for a total of 9 months.\n\nBoth groups will do the standard pelvic floor training program and both groups will be offered regular phosphodiesterase-5-inhibitor treatment. Before surgery, 3, 6 and 10 months after the patients will have to fill out four different questionnaires regarding sexual and urinary function, including IIEF-EF, EHS, \"neglected side effects\" and ICIQ-SF. (10 months is due to a wash-out period of 1 month after the intervention).\n\nThe collected data will be analysed and the primary goal is to see if there is a significant difference in average spontaneous IIEF-EF score in the two groups 10 months after the surgery.",[244,28],"Erectile Dysfunction Following Radical Prostatectomy","2024-03-08",{"date":247,"type":34},"2024-03-12",{"date":249,"type":34},"2024-02-01",{"date":251,"type":21},"2026-10",{"name":253,"class":41},"Herlev and Gentofte Hospital",{"id":255,"slug":256,"hasResults":11,"nctId":257,"briefTitle":258,"officialTitle":259,"acronym":4,"eligibilityCriteria":260,"healthyVolunteers":11,"sex":215,"minAge":18,"maxAge":4,"enrollmentInfo":261,"targetDuration":4,"studyType":22,"phases":263,"briefSummary":264,"conditions":265,"keywords":268,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":274,"lastUpdatePostDateStruct":275,"startDateStruct":277,"completionDateStruct":279,"leadSponsor":280,"locationsCount":42},"100232647","multicenter-study-for-diagnosis-and-treatment-of-perianal-abscesses-100232647","NCT02306382","Multicenter Study for Diagnosis and Treatment of Perianal Abscesses","Randomized Controlled Multicenter Study for Diagnosis and Treatment of Perianal Abscesses.","Inclusion Criteria:\n\n* perianal abscess that needs surgical treatment, over the age of 18\n\nExclusion Criteria:\n\n* Under the age of 18 or unable to understand study information because of language difficulties or dementia.",{"count":262,"type":21},200,[24],"Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife. After surgical intervention complications can occur with recidivism, chronic fistulas that go from the anal to the skin and sometimes the anal sphincter is damaged which can cause problems with incontinence.\n\nThrough ultrasound the abscess is opened under more controlled forms with a better visual overview. This is a new technique that has not been tested in larger studies. The aim with ultrasound-drainage as with traditional incision to drain the abscess so that the infected area can heal.\n\nThe hypothesis is a reduction of recurrences and formation of fistulas with the use of 3D ultrasonography.",[266,267,28],"Perianal Abscess","Anal Fistulas",[269,270,271,272,273],"endoanal ultrasonography","drainage","perianal abscess","fistulas","incontience","2023-11-28",{"date":276,"type":34},"2023-11-29",{"date":278,"type":4},"2012-12",{"date":229,"type":21},{"name":281,"class":41},"University Hospital, Umeå"]