[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"indeterminate-pulmonary-nodules\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:indeterminate-pulmonary-nodules":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100468116","ai--radiomics-for-stratification-of-lung-nodules-after-radically-treated-cancer-100468116",false,"NCT05375591","AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer","Artificial Intelligence & Radiomics for Stratification Of Lung Nodules After Radically Treated Cancer (AI-SONAR)","AI-SONAR","Inclusion Criteria:\n\n* Confirmed history of previous radically or curative-intent treated solid organ cancer within 10 years of new index CT thoracic scan demonstrating a new pulmonary nodule and either of the following:\n\n  * Biopsy confirming previous malignancy with MDT consensus and successful cancer resolution\u002Fremission following anti-cancer treatment on interval imaging or blood assay analysis\n  * Where biopsy was not possible\u002Fconfirmed for previous malignancy, MDT consensus outcome confirming cancer (+\u002F- calculated Herder score \\>80% if applicable) and decision to treat as malignancy with subsequent resolution\u002Fremission following anti-cancer treatment on interval imaging or blood assay analysis\n* Radical treatment for previous cancer defined as either of the following:\n\n  * Surgical resection\n  * Radical radiotherapy or stereotactic beam radiotherapy\n  * Radical chemotherapy\n  * Radical chemo-radiotherapy\n  * Multi-modality treatment with any of the above\n* New pulmonary nodule ground truth known\n\n  * Scan data showing 2-year stability (based on diameter or volumetry) or resolution in cases of benign disease\n  * Scan data showing progressive nodule enlargement or increase in nodule number on interval imaging with MDT consensus (+\u002F- PET with Herder score \\>80% if applicable) determining metastatic disease or new primary malignancy\n  * Biopsy sampling confirming benign disease or malignancy and in cases of malignancy, metastasis or new primary lung cancer\n* CT scan slice thickness ≤ 2.5mm\n* Nodule size ≥ 5mm\n\nExclusion Criteria:\n\n* CT Imaging \\> 10 years old\n* Non-solid haematological malignancies including leukaemia\n* Cases of radically treated primary cancer disease with early oligometastatic recurrence treated radically","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","This study will assess the utility of radiomics and artificial intelligence approaches to new lung nodules in patients who have undergone radical treatment for a previous cancer.",[25,26,27,28],"Indeterminate Pulmonary Nodules","Lung Metastases","Second Primary Cancer","Lung Cancer","RECRUITING","2022-05-17",{"date":32,"type":33},"2022-05-24","ACTUAL",{"date":35,"type":33},"2021-10-13",{"date":37,"type":21},"2026-11-01",{"name":39,"class":40},"Royal Marsden NHS Foundation Trust","OTHER",2]