[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"indirect-pulp-cap\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:indirect-pulp-cap":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100428758","phase-4-clinical-and-radiographic-success-of-mta-vs-biodentine-100428758",false,"NCT04863222","Clinical and Radiographic Success of MTA vs Biodentine","Clinical and Radiographic Success of Mineral Trioxide Aggregate (MTA) vs Septodont Biodentine in Primary Molars in Pulpotomy and Indirect Pulp Cap Treatments","Inclusion Criteria:\n\n* Male or female patients ages of 2 to ≤12 years.\n* Bilateral symptomatic or asymptomatic vital primary molars with caries approximating or into the pulp.\n* Patient who need a pulpotomy and\u002For indirect pulp cap treatments in two or more quadrants.\n* Parents of patients who can provide consent in English.\n* Patients who need treatment in an operating room setting at Geisinger.\n\nExclusion Criteria:\n\n* Pre-operative radiographic or clinical symptoms associated with irreversible pulpitis or necrotic pulp.\n* Radiographs not displaying furcation region of the tooth.\n* Patients with cardiac conditions who need prophylaxis for infective Endocarditis.\n* Patients with any type of cancer in the past or present.\n* Non-restorable molars.",true,"ALL","2 Years","12 Years",{"count":21,"type":22},646,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","The purpose of this prospective study is to compare the clinical and radiographic success of MTA and Biodentine as a medicament in vital pulp therapy in maxillary and mandibular primary molars in a pediatric population. There is limited research currently on Biodentine since it's a novel product. Biodentine is less expensive than MTA and does not cause discoloration like MTA. Biodentine may be an alternative medicament used for vital pulp therapy in primary molars.",[28,29],"Indirect Pulp Cap","Pulpotomy","RECRUITING","2025-12-22",{"date":33,"type":34},"2025-12-23","ACTUAL",{"date":36,"type":34},"2021-11-12",{"date":38,"type":22},"2026-12-01",{"name":40,"class":41},"Geisinger Clinic","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":42},"100607050","a-study-comparing-eggshell-based-and-gold-standard-materials-to-heal-deep-tooth-damage-in-adult-molars-100607050","NCT07183514","A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars","Clinical and Radiographic Evaluation of Eggshell-derived Calcium Hydroxyapatite Verses Calcium Hydroxide as In-direct Pulp Capping Agent in Permanent Molars","Inclusion Criteria:\n\n1. Teeth with symptoms of reversible pulpitis.\n2. Teeth that show positive response on electric pulp testing (EPT).\n3. Teeth with caries penetrating up to three-quarters (¾) of dentine without pulp involvement.\n4. Healthy cooperative patients of both sexes between 18 to 40 years of age.\n\n   \\-\n\nExclusion Criteria:\n\n1. Necrosed Teeth with radiolucency in the periapical and furcation regions.\n2. Tooth with internal and external root resorption.\n3. Periodontally compromised tooth. (BPE score 3 and above)\n4. Physically and mentally handicapped patients. (ASA score 3 and above)","18 Years","40 Years",{"count":53,"type":22},54,[55],"NA","This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth. A total of 54 teeth from healthy individuals aged 18 to 40 years will be randomly allocated into two groups:\n\nGroup A (experimental) treated with eggshell-derived calcium hydroxyapatite. Group B (control) treated with calcium hydroxide.\n\nAfter caries removal the assigned pulp capping agent will be applied, and the teeth will be restored. Clinical and radiographic evaluations will be performed at 1 and 3 months to assess pulp vitality, symptom-free status, and periapical health.",[28],[59],"dental caries, indirect pulp capping, hydroxyapatite, reparative dentine","NOT_YET_RECRUITING","2025-09-16",{"date":63,"type":34},"2025-09-19",{"date":65,"type":22},"2025-09-20",{"date":67,"type":22},"2026-03-31",{"name":69,"class":41},"University of Health Sciences Lahore",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":76,"maxAge":51,"enrollmentInfo":77,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":81,"conditions":82,"keywords":92,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":42},"100584440","phase-2-clinical-and-radiographic-evaluation-of-indirect-pulp-capping-using-platelet-rich-fibrin-versus-mineral-trioxide-aggregate-in-deep-carious-molars-a-randomized-controlled-trial-100584440","NCT06889363","Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial","Inclusion Criteria:\n\n* o Patients with asymptomatic deep carious molars.\n\n  * Patients with clinically and radiographically confirmed deep carious lesions that do not exhibit spontaneous pain.\n  * Permanent molars only.\n  * Teeth with intact or minimally restored occlusal surfaces (i.e., no extensive restorations or fractures).\n  * No history of previous endodontic treatment or direct pulp capping on the study tooth.\n  * No signs of periapical pathology based on radiographic evaluation.\n  * Patients willing to participate and follow up for 12 months.\n  * Patients who agree to return for scheduled follow-ups at 3, 6, and 12 months.\n\nExclusion Criteria:\n\n* o Patients with systemic conditions affecting bone or tissue healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppressed conditions).\n\n  * Pregnant or lactating women (if applicable to your study).\n  * Teeth with pulp exposure or necrotic pulp.\n  * Presence of symptomatic irreversible pulpitis (e.g., spontaneous pain, lingering pain).\n  * Periapical pathology or internal\u002Fexternal resorption detected radiographically.\n  * Severely broken down or non-restorable teeth.\n  * Calcified root canals or excessive sclerosis that could affect pulp testing reliability.\n  * Any pre-existing root canal treatment on the selected tooth.\n  * Patients who have undergone recent fluoride treatment, pulpotomy, or other pulp therapies in the past 6 months.\n  * Patients using medications affecting bone and tissue regeneration (e.g., bisphosphonates, corticosteroids).\n  * Patients unwilling or unable to commit to the 12-month follow-up schedule.\n  * Patients with poor oral hygiene or high caries risk that could compromise treatment outcomes.","20 Years",{"count":78,"type":22},50,[80],"PHASE2","The aim of this study is the clinical and radiographic evaluation of (Platelet-Rich Fibrin (PRF) versus Mineral Trioxide Aggregate (MTA) in indirect pulp capping when used with deep carious molars over 1 year follow up.",[83,84,85,28,86,87,88,89,90,91],"Dental Caries","Pulp Caping","Indirect Pulp Treatment","Indirect Pulp Capping","Indirect Pulp Therapy","Deep Carious Lesion","Deep Carious Lesions","Molar Caries","Carious Molars",[93,94,95,96,97,98,99],"Molar caries","MTA","PRF","Indirect pulp capping","Deep carious lesion","carious molars","platelet rich fibrin","2025-03-17",{"date":102,"type":34},"2025-03-21",{"date":104,"type":22},"2025-06",{"date":106,"type":22},"2026-09",{"name":108,"class":41},"Cairo University"]