[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"indirect-pulp-capping\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:indirect-pulp-capping":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100568638","phase-4-comparison-between-egyptian-mta-biodentine-versus-calcium-hydroxide-as-indirect-pulp-capping-materials-in-permanent-teeth-100568638",false,"NCT06683833","Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Teeth","Comparative Analysis of Egyptian MTA, Biodentine, and Calcium Hydroxide as Indirect Pulp Capping Materials in Permanent Teeth. (A 6m Randomized Clinical Trial)","Inclusion Criteria:\n\n* Adult patients aged 22: 45 years old.\n* Males or females.\n* Patients with vital teeth with deep carious lesions.\n* Patients in good general health.\n* Good oral hygiene.\n* Co-operative patients who show interest to participate in the study.\n\nExclusion Criteria:\n\n* Patients with systemic diseases.\n* Patients with known allergic or adverse reaction to the tested materials.\n* Patients with bad oral hygiene.\n* Patient who frequently use analgesic or any drugs that could mask the pain.","ALL","22 Years","45 Years",{"count":20,"type":21},35,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Compare the clinical performance and patient satisfaction of Egyptian MTA, Biodentine versus Calcium Hydroxide as indirect pulp capping materials in permanent teeth",[27,28,29,30,31,32],"Deep Caries","Indirect Pulp Capping","Mineral Trioxide Aggregate (MTA)","Calcium Hydroxide","Biodentine","Patient Reported Outcome Measures",[34,35,36,37,31,38,39],"Deep caries","Indirect pulp capping","Mineral trioxide aggregate (MTA)","Calcium hydroxide","Patient reported outcomes measures (PROMS)","Randomized clinical trial","RECRUITING","2026-03-17",{"date":43,"type":44},"2026-03-18","ACTUAL",{"date":46,"type":44},"2025-09-03",{"date":48,"type":21},"2026-07-03",{"name":50,"class":51},"Cairo University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":16,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":52},"100549383","comparative-evaluation-of-indirect-vs-direct-pulp-capping-in-deep-carious-mandibular-molars-100549383","NCT06433297","Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars","Comparative Evaluation of Indirect and Direct Pulp Capping After Partial or Complete Caries Removal in Deeply Carious Mature Permanent Mandibular Molars With Moderate Pulpitis: A Randomized Clinical Trial","Inclusion Criteria:\n\n1. The patient should be ≥18 years of age.\n2. Restorable mature permanent 1st and 2nd Mandibular molars with deep caries (reaching inner quarter of dentine)\n3. Tooth should give positive response to pulp sensibility testing.\n4. Clinical diagnosis of moderate pulpitis.\n5. Radiographic finding of periapical index (PAI) score ≤2.\n6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).\n7. Pulp exposure after complete caries excavation.\n8. No pulp exposure after incomplete caries excavation\n\nExclusion Criteria:\n\n1. Teeth with immature roots.\n2. Pulp exposure after incomplete caries excavation.\n3. No pulp exposure after complete caries excavation.\n4. Bleeding could not be controlled in 5 minutes.\n5. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.\n6. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.\n7. Internal\u002Fexternal resorption.\n8. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)",true,"18 Years",{"count":63,"type":21},106,[65],"NA","Aim: To compare the outcome of indirect and direct pulp capping after partial or complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n\nObjectives:\n\n1. To evaluate the clinical and radiographic success of indirect pulp capping after partial caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n2. To evaluate the clinical and radiographic success of direct pulp capping after complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n3. To evaluate pain incidence and severity after indirect and direct pulp capping after partial and complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.",[28,68],"Reversible Pulpitis",[70,71,72,73,74,75,76],"indirect pulp capping","selective caries removal","moderate pulpitis","direct pulp capping","deep caries","complete caries removal","mature permanent mandibular molars","2026-02-09",{"date":79,"type":44},"2026-02-12",{"date":81,"type":44},"2024-05-23",{"date":83,"type":21},"2026-03-23",{"name":85,"class":51},"Postgraduate Institute of Dental Sciences Rohtak",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":96,"briefSummary":98,"conditions":99,"keywords":109,"overallStatus":116,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":52},"100584440","phase-2-clinical-and-radiographic-evaluation-of-indirect-pulp-capping-using-platelet-rich-fibrin-versus-mineral-trioxide-aggregate-in-deep-carious-molars-a-randomized-controlled-trial-100584440","NCT06889363","Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial","Inclusion Criteria:\n\n* o Patients with asymptomatic deep carious molars.\n\n  * Patients with clinically and radiographically confirmed deep carious lesions that do not exhibit spontaneous pain.\n  * Permanent molars only.\n  * Teeth with intact or minimally restored occlusal surfaces (i.e., no extensive restorations or fractures).\n  * No history of previous endodontic treatment or direct pulp capping on the study tooth.\n  * No signs of periapical pathology based on radiographic evaluation.\n  * Patients willing to participate and follow up for 12 months.\n  * Patients who agree to return for scheduled follow-ups at 3, 6, and 12 months.\n\nExclusion Criteria:\n\n* o Patients with systemic conditions affecting bone or tissue healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppressed conditions).\n\n  * Pregnant or lactating women (if applicable to your study).\n  * Teeth with pulp exposure or necrotic pulp.\n  * Presence of symptomatic irreversible pulpitis (e.g., spontaneous pain, lingering pain).\n  * Periapical pathology or internal\u002Fexternal resorption detected radiographically.\n  * Severely broken down or non-restorable teeth.\n  * Calcified root canals or excessive sclerosis that could affect pulp testing reliability.\n  * Any pre-existing root canal treatment on the selected tooth.\n  * Patients who have undergone recent fluoride treatment, pulpotomy, or other pulp therapies in the past 6 months.\n  * Patients using medications affecting bone and tissue regeneration (e.g., bisphosphonates, corticosteroids).\n  * Patients unwilling or unable to commit to the 12-month follow-up schedule.\n  * Patients with poor oral hygiene or high caries risk that could compromise treatment outcomes.","20 Years","40 Years",{"count":95,"type":21},50,[97],"PHASE2","The aim of this study is the clinical and radiographic evaluation of (Platelet-Rich Fibrin (PRF) versus Mineral Trioxide Aggregate (MTA) in indirect pulp capping when used with deep carious molars over 1 year follow up.",[100,101,102,103,28,104,105,106,107,108],"Dental Caries","Pulp Caping","Indirect Pulp Treatment","Indirect Pulp Cap","Indirect Pulp Therapy","Deep Carious Lesion","Deep Carious Lesions","Molar Caries","Carious Molars",[110,111,112,35,113,114,115],"Molar caries","MTA","PRF","Deep carious lesion","carious molars","platelet rich fibrin","NOT_YET_RECRUITING","2025-03-17",{"date":119,"type":44},"2025-03-21",{"date":121,"type":21},"2025-06",{"date":123,"type":21},"2026-09",{"name":50,"class":51}]