[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"induction-of-labor\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:induction-of-labor":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,48,79,107,130,156,178,200,220,246,268],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100624833","safety-and-usability-of-the-inga-catheter-for-labor-induction-inga-mdp-100624833",false,"NCT07414771","Safety and Usability of the Inga Catheter for Labor Induction (INGA-MDP)","A Medical Device Pilot Study to Evaluate the Safety and Usability of the Inga Catheter in Labor Induction","INGA-MDP","Inclusion Criteria:\n\n* Pregnant women aged ≥18 and ≤56 years\n* An unripe cervix, ≤6 points according to the Bishop assessment (0-10 point scale)\n* Planned induction of labor by mechanical balloon catheter method\n* Examples of diagnoses as the basis for labor induction:\n\n  * Post-term pregnancy (≥41 weeks of gestation)\n  * Maternal request for labor induction\n  * Gestational diabetes\n  * Preeclampsia (with blood pressure \\\u003C150\u002F100)\n  * Well-controlled hypertension\n  * Cholestasis of pregnancy\n  * Humanitarian or psychosocial reasons\n* Gestational age at the time of the study ≥ 37 weeks (gestational age confirmed by ultrasound before the 21st week of pregnancy)\n* Singleton pregnancy\n* Cephalic presentation\n* The subject understands the study information and signs the consent form\n\nExclusion Criteria:\n\n* Preterm induction of labor (\\\u003C37 weeks of gestation)\n* Pathological CTG at inclusion\n* Spontaneous rupture of membranes at inclusion\n* Clinically significant vaginal bleeding with need of hospitalization in the third trimester\n* Clinically active vaginal or uterine infection\n* Maternal HIV, hepatitis C, or hepatitis B\n* Uterine scar (including previous cesarean section)\n* Condition of the fetus or mother requiring immediate delivery\n* Presence of eclampsia\n* Severe Pre-eclampsia (Blood pressure ≥160\u002F110 and any of the following: low platelet count (\\\u003C100 × 10 9\u002FL), HELLP, progressive renal insufficiency, pulmonary edema)\n* Severe fetal growth restriction (FGR, fetal growth \\\u003C -2 SD)\n* Estimated fetal weight ≥ 2SD or ≥ 95th percentile\n* Breech or transverse fetal position\n* Multiple pregnancy\n* Vasa previa or placenta previa\n* Umbilical cord prolapse\n* Maternal refusal to participate in the study and\u002For insufficient language skills to understand the study information and\u002For consent form","FEMALE","18 Years","56 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical study is to evaluate a new mechanical balloon catheter (INGA) used to prepare the cervix for labor induction in pregnant women at term.\n\nThe study aims to assess the safety, usability, and performance of the INGA catheter when used for cervical ripening before labor. Researchers will also collect feedback from healthcare professionals and participants about the use of the device.\n\nParticipants are pregnant women at term with a single baby in a head-down position who meet the study eligibility criteria.\n\nParticipants will:\n\n* have the INGA balloon catheter inserted as part of labor induction,\n* receive standard clinical care according to hospital practice,\n* provide information about their experience and outcomes related to the device.\n\nThe results of this study will help determine whether the INGA catheter is safe and suitable for use in cervical ripening during labor induction.",[28,29,30],"Induction of Labor","Cervical Ripening","Cervical Ripening and Induction of Labor",[32,33,34],"Cervical ripening","Balloon catheter","Induction of labor","NOT_YET_RECRUITING","2026-05-22",{"date":38,"type":39},"2026-05-26","ACTUAL",{"date":41,"type":22},"2026-05",{"date":43,"type":22},"2027-03-31",{"name":45,"class":46},"Aalto University","OTHER",3,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100638216","is-nipple-stimulation-effective-for-inducing-labor-and-acceptable-to-patients-nurses-and-providers-100638216","NCT07588529","Is Nipple Stimulation Effective for Inducing Labor and Acceptable to Patients, Nurses, and Providers?","Nipple Stimulation Acceptability for Induction of Labor","NSAIL","Inclusion Criteria:\n\nAll patients presenting to KUMC labor \\& delivery for IOL will be considered for this study.\n\nMaternal\n\n* ≥18 years old and ≤ 50 years old\n* ≥37wga and ≤ 42wga\n* Intact amniotic membranes\n* English speaking Fetal\n* Cephalic presentation\n\nExclusion Criteria:\n\nMaternal\n\n* Inability to give informed consent\n* History of cesarean delivery or uterine myomectomy\n* History of uterine rupture\n* Intrahepatic cholestasis of pregnancy\n* Maternal life-threatening conditions\n* Active HSV\n* Gestational hypertension, Preeclampsia (severe or w\u002Fo severe features), HELLP, chronic hypertension on medications\n\nPlacental\n\n* Placenta previa, vasa previa\n* Suspicion for abnormally adherent placenta\n* Chorioamnionitis\n* Placental abruption\n\nFetal\n\n* Multifetal gestation\n* category 2 or 3 fetal heart tracing upon presentation (does not include isolated variable deceleration)\n* EFW \\> 5000 grams in mother with diabetes\n* EFW \\> 4500 grams in mother without diabetes\n* Fetal demise\n* Fetal growth restriction \\\u003C10th centile\n* Any other contraindication for vaginal birth or anticipation of need for NICU for care of baby","50 Years",{"count":58,"type":22},48,[25],"In this study the investigators will be testing the use of the Symphony PLUS® breast pump for nipple stimulation. Typically, breast pumps are used to start breast milk production and collect breast milk in patients after delivering their baby. The device uses cup-shaped pieces called flanges that are placed over the patient's nipples and then a gentle vacuum or suction is applied. The mechanical effect of the suction on the nipple is thought to cause the release of a substance called oxytocin in one's body, which encourages labor and contractions to begin. Some reasons why nipple stimulation might be better than other induction of labor methods are that it allows the patient to have more control over their induction process, it uses the patient's own oxytocin instead of synthetic (or factory-produced) oxytocin, and it may shorten the time that it takes to deliver the baby.",[62,28],"Pregnancy",[64,65,66,67,68],"nipple stimulation","breast stimulation","induction","labor","induction of labor","2026-05-08",{"date":71,"type":39},"2026-05-14",{"date":73,"type":22},"2026-07",{"date":75,"type":22},"2028-12",{"name":77,"class":46},"University of Kansas Medical Center",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":78},"100638328","natural-cervical-ripening-to-prevent-pharmacological-induction-of-labor---a-pilot-study-100638328","NCT07587632","Natural Cervical Ripening to Prevent Pharmacological Induction of Labor - a Pilot Study.","Cervinat","Inclusion Criteria:\n\n* Singleton gestation\n* Non-insulin dependent, dietetically managed gestational diabetes\n* Greater than or equal to 34 weeks.\n* Planned vaginal birth at the University Hospital of Zurich\n* Planned IOL for 40 weeks of gestation.\n* Communication in German and\u002For English language possible.\n\nExclusion Criteria:\n\n* Pregnant women with multiple gestation\n* Fetal macrosomia \\>95th percentile\n* Intrauterine growth restriction \\\u003C3rd percentile\n* Already in labor (regular contractions or premature rupture of membranes (PROM)\n* Patients scheduled for IOL before 40 weeks\n* Insulin-dependent diabetes\n* Planned cesarean section\n* Planned birth in an external hospital\n* Inability to follow the procedures e.g. due to language problems, psychological disorders",{"count":87,"type":22},74,[25],"As of today, around 25% of all vaginal births happen after induction of labor (IOL). The internal guidelines of the University Hospital Zurich currently recommend pregnant women with a non-insulin dependent gestational diabetes an IOL around term. One possibility to prevent an IOL and increase the chance for a spontaneous onset of birth is a ripening of the cervix by alternative methods in an outpatient setting. The primary objective of this study is to evaluate the effect of natural cervical ripening methods on the time interval between 37 weeks (beginning of the intervention) and the onset of spontaneous labor.",[62,28,91],"Gestational Diabetes Mellitus (GDM)",[93,34,94,95,96,97],"gestational Diabetes","cervical ripening","pregnancy","colostrum banking","membrane sweeping","RECRUITING","2026-05-07",{"date":71,"type":39},{"date":102,"type":39},"2026-04-10",{"date":104,"type":22},"2029-12-31",{"name":106,"class":46},"University of Zurich",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":114,"sex":17,"minAge":18,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":118,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":78},"100541834","castor-oil-ingestion-and-balloon-catheter-for-labor-induction-in-multiparous-100541834","NCT06335017","Castor Oil Ingestion and Balloon Catheter for Labor Induction in Multiparous","The Effect of Combining Balloon Catheter With Castor Oil Ingestion for Cervical Ripening on Time to Delivery Among Multiparous Women.","Inclusion Criteria:\n\n* Women above 18 years old\n* Sign an informed consent\n* Term pregnancy (\\>37 weeks)\n* Viable fetus\n* Singleton\n* Vertex presentation\n* Intact membranes\n* Cervix with Bishop score ≤6\n\nExclusion Criteria:\n\n* Previous cesarean delivery\n* Major fetal malformations\n* Contraindication to spontaneous vaginal delivery\n* Amniotic fluid index \\>25cm\n* Chorioamnionitis at admission\n* Placental abruption\n* Previous prostaglandin use for induction of labor\n* A low-lying placenta (up to 2 cm from the internal os)\n* Carriers of hepatitis B or C or human immunodeficiency viruses,\n* Women with a history of allergy to latex.\n* Women with a history of allergy to castor oil",true,"60 Years",{"count":117,"type":22},216,[25],"The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in multiparous women.\n\nThe main question it aims to answer are:\n\nDoes the addition of the use of castor oil to extra-amniotic single balloon reduce the time until birth? Does the addition of the castor oil affect other perinatal outcomes during childbirth? Are the side effects of the castor tolerated by the mothers? Participants will be randomly divided into 2 groups: the study group will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, extra-amniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline.\n\nIn the control group, the catheter will be inserted into cervical canal without ingestion of castor oil.",[28],"2026-04-07",{"date":123,"type":39},"2026-04-13",{"date":125,"type":39},"2024-04-10",{"date":127,"type":22},"2026-12",{"name":129,"class":46},"Holy Family Hospital, Nazareth, Israel",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":23,"phases":140,"briefSummary":141,"conditions":142,"keywords":144,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100630966","induction-of-labor-by-cervical-ripening-and-transcutaneous-electrical-nerve-stimulation-tens-100630966","NCT07494539","Induction of Labor by Cervical Ripening and Transcutaneous Electrical Nerve Stimulation (TENS)","Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Artificial Induction of Labor by Cervical Ripening.","DETENS","Pregnant women requiring labor induction by cervical ripening at the Intercommunal Hospital Center of Poissy-Saint-Germain-en-Laye will be screened for eligibility according to the following criteria.\n\nInclusion Criteria:\n\n* Pregnant women aged 18 years or older\n* Gestational age ≥ 37 weeks of amenorrhea\n* Indication for labor induction requiring cervical ripening\n* Planned cervical ripening using oral misoprostol (Angusta)\n* Singleton pregnancy\n* Able to provide written informed consent\n* Affiliated with or beneficiary of a social security system\n\nExclusion Criteria:\n\n* Contraindication to labor induction by cervical ripening\n* Contraindication to epidural analgesia\n* Major fetal anomaly\n* Maternal hypertension or hypotension\n* Maternal pacemaker and\u002For cardiac rhythm disorders\n* Presence of metallic prosthesis regardless of location\n* Ongoing deep vein thrombosis or under treatment for thrombosis\n* Epilepsy\n* Fever at the time of inclusion\n* Participant under legal protection (guardianship or curatorship)\n* Inability to understand the French language",{"count":139,"type":22},132,[25],"This study aims to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) for pain management during labor induction by cervical ripening.\n\nLabor induction is a common obstetric procedure and cervical ripening may be associated with painful uterine contractions. Non-pharmacological analgesic methods such as TENS could help improve pain management during this phase. However, evidence regarding its effectiveness in this context remains limited.\n\nThis randomized, controlled, open-label monocentric study will compare the use of TENS in addition to usual analgesic care versus usual analgesic care alone in pregnant women undergoing labor induction with cervical ripening. The primary objective is to assess whether TENS reduces the need for neuraxial analgesia or delays its use during labor.",[143,28],"Labor Pain",[145,68,146],"labor pain","TENS","2026-03-20",{"date":149,"type":39},"2026-03-27",{"date":151,"type":22},"2026-04-01",{"date":153,"type":22},"2028-04-01",{"name":155,"class":46},"HOT Noémie",{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":114,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":163,"targetDuration":4,"studyType":23,"phases":165,"briefSummary":166,"conditions":167,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":171,"completionDateStruct":173,"leadSponsor":175,"locationsCount":4},"100617365","combined-nipple-stimulation-and-foley-balloon-for-cervical-ripening-100617365","NCT07317674","Combined Nipple Stimulation and Foley Balloon for Cervical Ripening","The Effect of Nipple Stimulation Combined With Foley Balloon Catheter on Bishop Score and Induction-to-delivery Interval: a Prospective Randomized Trial","Inclusion Criteria:\n\n* Pregnant individuals aged ≥18 years\n* Singleton pregnancy\n* Term gestation (37-42 weeks)\n* Cephalic fetal presentation\n* Intact membranes\n* Bishop score \\\u003C6 at enrollment\n* Medical indication for labor induction\n\nExclusion Criteria:\n\n* Multiple gestation\n* Previous cesarean delivery or uterine surgery\n* Contraindication to vaginal delivery\n* Major fetal anomalies\n* Active labor at enrollment\n* Unstable fetal lie or presentation\n* Contraindication to Foley balloon catheter insertion\n* Conditions precluding nipple stimulation (e.g., local breast infection, prior breast surgery involving the nipple)",{"count":164,"type":22},100,[25],"Labor induction rates have increased substantially worldwide, and successful cervical ripening remains a key determinant of induction outcomes. Mechanical cervical ripening with a Foley balloon catheter is widely used and considered safe, while nipple stimulation promotes endogenous oxytocin release and represents a physiologic method for stimulating uterine contractions. However, the combined effect of nipple stimulation and balloon catheter use has not been systematically evaluated.\n\nThis prospective, randomized, double-blinded controlled trial will assess whether the addition of nipple stimulation to Foley balloon catheter cervical ripening improves Bishop score and shortens the induction-to-delivery interval compared with balloon catheter alone. Term pregnant patients (37-42 weeks' gestation) with a singleton, cephalic pregnancy and an unfavorable cervix (Bishop score \\\u003C6) requiring labor induction will be randomized to receive either Foley balloon catheter plus standardized nipple stimulation or Foley balloon catheter alone.\n\nThe primary outcomes are change in Bishop score after catheter removal and time from catheter insertion to delivery. Secondary outcomes include need for additional induction methods, mode of delivery, maternal and neonatal outcomes, pain, patient satisfaction, and breastfeeding rates. The study aims to evaluate the efficacy and safety of incorporating a physiologic intervention into standard mechanical cervical ripening.",[28,29],"2025-12-19",{"date":170,"type":39},"2026-01-05",{"date":172,"type":22},"2026-01-01",{"date":174,"type":22},"2028-01-01",{"name":176,"class":177},"Western Galilee Hospital-Nahariya","OTHER_GOV",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":115,"enrollmentInfo":185,"targetDuration":4,"studyType":23,"phases":187,"briefSummary":189,"conditions":190,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":78},"100577876","phase-4-induction-of-labor---comparison-propess-with-prostaglandin-e2-vaginal-gel-and-balloon-catheter-100577876","NCT06803992","Induction of Labor - Comparison Propess With Prostaglandin E2 Vaginal Gel and Balloon Catheter","Induction of Labor in Women With Unfavorable Cervix at Term - Comparison of Propess Versus Prostaglandin E2 Vaginal Gel and Extra-amniotic Balloon Catheter","Inclusion Criteria:\n\n* Pregnant women at term (37 weeks of gestation or more) with singleton\n* pregnancies that are intended for IOL.\n* Initial bishop score \\\u003C5\n* No contraindications to receive either treatment.\n* Women who will give informed consent to be included in the study.\n* Women at or over the age of 18.\n\nExclusion Criteria:\n\n* Women with a known hypersensitivity or contraindications to Propess \u002F PGE2.\n* Parity 5 or more\n* Labor contractions more than 4 in 20 min\n* Glaucoma\n* History of previous uterine surgery\n* Hypersensitivity to prostaglandins\n* Vaginal delivery is contraindicated\n* Active cardiac, renal, pulmonary, or hepatic disease\n* Severe asthma or pulmonary disease",{"count":186,"type":22},140,[188],"PHASE4","One of every four births in the Western world is induced, usually due to the risk of maternal and fetal morbidity. There are several methods of labor induction, pharmacological and mechanical. In cases of unfavorable cervix (Bishop score is below 5), cervical ripening can be induced by either prostaglandins E2 (slow release 10 mg dinoprostone insert (propess) or vaginal gel 1-2 mg) or mechanically by Foley catheter balloon (FCB).\n\nThe efficacy of labor induction of propess versus vaginal gel combined with FCB was not studied previously.\n\nThe goal of this randomized controlled trial is to compare the efficacy of propess versus PGE2 vaginal gel combined with FCB in women with singletons undergoing labor induction at term. The main question it aims to answer is to compare the time from the beginning of labor induction until delivery.",[28],"2025-11-24",{"date":193,"type":39},"2025-12-01",{"date":195,"type":39},"2025-04-06",{"date":197,"type":22},"2027-01-29",{"name":199,"class":46},"HaEmek Medical Center, Israel",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":114,"sex":17,"minAge":18,"maxAge":206,"enrollmentInfo":207,"targetDuration":4,"studyType":23,"phases":209,"briefSummary":210,"conditions":211,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":218,"locationsCount":4},"100593762","dilapan-s-versus-double-balloon-catheter-crb-for-preinduction-of-labor-at-term-100593762","NCT07010653","Dilapan-S Versus Double Balloon Catheter (CRB) for Preinduction of Labor at Term","Inclusion Criteria:\n\n* • Singleton pregnancy\n\n  * Cephalic fetal presentation\n  * Gestational age ≥ 37+0 weeks\n  * Indication for labor induction (e.g., postdates, maternal hypertension)\n  * Bishop score ≤ 6\n  * Maternal age ≥18 years\n  * Ability to provide informed consent\n\nExclusion Criteria:\n\n* • Premature rupture of membranes (PROM)\n\n  * Placenta previa, vasa previa, or abnormal placentation\n  * Active genital tract infection\n  * Prior classical cesarean section or extensive uterine surgery\n  * Known fetal anomaly contraindicating vaginal delivery\n  * Allergy or sensitivity to device materials\n  * Any contraindication to labor induction or vaginal birth","45 Years",{"count":208,"type":22},126,[25],"Induction of labor (IOL) is a frequently performed procedure in obstetrics, aimed to achieve vaginal delivery when continuing the pregnancy is no longer advisable. A key determinant of IOL success is cervical ripening, particularly when the cervix is initially unfavorable. A range of preinduction methods is available, encompassing both mechanical and pharmacological approaches. Among mechanical techniques, the double balloon catheter (CRB) facilitates cervical dilation by applying direct pressure, which stimulates local prostaglandin release. In contrast, Dilapan-S, a synthetic osmotic dilator, works by gradually expanding through the absorption of cervical fluids, thereby applying gentle mechanical pressure.\n\nWhile both methods are widely used and generally considered safe, there is limited evidence directly comparing their effectiveness and patient-centered outcomes. Mechanical methods are associated with a lower risk of uterine hyperstimulation compared to pharmacological alternatives. The choice between CRB and Dilapan-S may significantly influence labor duration, cesarean delivery rates, maternal comfort, and hospital resource utilization. This study aims to fill the existing knowledge gap by directly comparing Dilapan-S and CRB for term preinduction, with a focus on clinical efficacy and maternal satisfaction.",[28],"2025-05-29",{"date":214,"type":39},"2025-06-08",{"date":216,"type":22},"2025-09",{"date":127,"type":22},{"name":219,"class":46},"University of Roma La Sapienza",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":4,"eligibilityCriteria":226,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":227,"targetDuration":4,"studyType":23,"phases":229,"briefSummary":230,"conditions":231,"keywords":233,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":78},"100592191","phase-4-comparing-high-versus-low-dose-of-oxytocin-in-gravida-women-with-bmi-30-and-above-which-are-undergoing-induction-of-labor-100592191","NCT06990217","Comparing High Versus Low Dose of Oxytocin, in Gravida Women With BMI 30 and Above Which Are Undergoing Induction of Labor","Comparison of Oxytocin Dosing Regimen' Low Versus High, in Gravida Women With BMI 30 and Above Undergoing Induction of Labor","Inclusion Criteria:\n\n* Women at term (37-42 weeks), requiring the use of oxytocin for induction of labor or for augmentation of labor.\n* BMI 30 and above\n* Viable singleton pregnancies\n* Cephalic presentation.\n* No contraindication for vaginal delivery\n\nExclusion Criteria:\n\n* Women with previous cesarean delivery\n* Multiple pregnancy\n* Multiple fetal malformations\n* IUFD",{"count":228,"type":22},130,[188],"The goal of this clinical trial is to compare between higher and lower dose of oxytocin to induce delivery in obese women. Researches will compare between low and high doses of oxytocin. the study group will use high dose of oxytocin (20 units in 1000 ml) versus the control group which will use low dose of oxytocin (10 units of oxytocin in 1000 ml)",[28,232],"Augmentation of Labor",[68,234,235,236,237],"augmentation of labor","obese","obese gravida","high dose of oxytocin in obese gravida","2025-05-17",{"date":240,"type":39},"2025-05-25",{"date":242,"type":22},"2025-06",{"date":244,"type":22},"2027-12",{"name":199,"class":46},{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":250,"acronym":4,"eligibilityCriteria":251,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":252,"enrollmentInfo":253,"targetDuration":4,"studyType":23,"phases":255,"briefSummary":257,"conditions":258,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":262,"completionDateStruct":264,"leadSponsor":266,"locationsCount":4},"100557581","early-phase-1-effectiveness-of-evening-primrose-oil-for-induction-of-labor-100557581","NCT06539975","Effectiveness of Evening Primrose Oil for Induction of Labor","Inclusion Criteria:\n\n* pregenent of 38 weeks and longer\n* singleton pregenency\n* vertex presentation\n* indication of labor induction\n* bishop score \\\u003C6 and cervical dilation\\\u003C2 cm\n\nExclusion Criteria:\n\n* women who delivered by classical cs or had a history of myomectomy , hysterscopic uterine surgery , or cervical surgery like conisation\n* women with multiple gestation\n* women with evidence of low implanted placenta by ultrasound\n* women with contraindication to misoprostol or vaginal delivery","35 Years",{"count":254,"type":22},72,[256],"EARLY_PHASE1","Effectivness of primrose oil in induction of labour .",[28],"2024-08-02",{"date":261,"type":39},"2024-08-06",{"date":263,"type":22},"2024-12-10",{"date":265,"type":22},"2025-10-12",{"name":267,"class":46},"Assiut University",{"id":269,"slug":270,"hasResults":11,"nctId":271,"briefTitle":272,"officialTitle":273,"acronym":4,"eligibilityCriteria":274,"healthyVolunteers":114,"sex":17,"minAge":18,"maxAge":206,"enrollmentInfo":275,"targetDuration":4,"studyType":23,"phases":277,"briefSummary":278,"conditions":279,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":280,"lastUpdatePostDateStruct":281,"startDateStruct":283,"completionDateStruct":285,"leadSponsor":287,"locationsCount":4},"100510105","cervical-ripening-balloon-for-12-hours-vs-1-hour-100510105","NCT05922111","Cervical Ripening Balloon for 12 Hours vs. 1 Hour.","Comparison of Labor Induction With Cervical Ripening Balloon, One Versus Tweleve Hours Placement: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Nulliparous or multiparous gravidas\n2. Gestational age ≥ 370\u002F7 to 416\u002F7 gestational weeks\n3. Age 18-45\n4. Signed informed consent\n\nExclusion Criteria:\n\n1. Contraindications for vaginal delivery\n2. Multifetal gestation\n3. Rupture of membranes\n4. Bishop score \\> 6\n5. The cervix is dilated to more than 2 cm\n6. Previous caesarean delivery",{"count":276,"type":22},164,[25],"The aim of this study is a comparison of induction of labor with a cervical ripening balloon left in place for one hour compared to twelve hours. The primary outcome is time to delivery.\n\nWomen admitted for induction of labor will be recruited and randomized to either a cervical ripening balloon for one hour or twelve hours. the management of delivery after the extraction of the balloon will be left to the discretion of the attending physician.",[28],"2023-06-18",{"date":282,"type":39},"2023-06-28",{"date":284,"type":22},"2023-08-01",{"date":286,"type":22},"2026-06-30",{"name":288,"class":46},"Rambam Health Care Campus"]