[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"infant-developmental-assessment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:infant-developmental-assessment":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100633364","the-relationship-between-finger-ratio-and-development-in-infants-100633364",false,"NCT07525726","The Relationship Between Finger Ratio and Development in Infants","The Relationship Between Digit Ratio and Motor Development and Sensory Processing in Infants","Inclusion Criteria:\n\n* Term infants (37-40 weeks),\n* Infants aged 12-18 months\n\nExclusion Criteria:\n\n* Preterm infants,\n* Infants with congenital infections or proven genetic changes,\n* Infants and mothers diagnosed with metabolic, neurological, and genetic diseases,\n* Maternal diabetes,\n* Intrauterine growth retardation,\n* Infants with a history of hand-related surgery,\n* Children whose parents did not volunteer to study",true,"ALL","12 Months","18 Months",{"count":21,"type":22},80,"ESTIMATED","OBSERVATIONAL","One of the most prominent indicators of prenatal androgen exposure is considered to be the ratio of second and fourth finger lengths (2D:4D). The 2D:4D finger ratio refers to the ratio of the length of the second finger (2D; index finger) and the fourth finger (4D; ring finger). Evidence suggests that 2D:4D is developmentally stable and stabilizes from the second trimester of pregnancy. It has been reported that the 2D:4D ratio correlates positively with estrogen and negatively with testosterone. In both sexes, prenatal testosterone levels are inversely related by a 2D:4D ratio, which does not change with age. Androgens can have direct trophic effects on target cells or indirectly affect neuronal growth through neurotrophic mediators released locally by steroid-sensitive neuronal or glial cells. Prenatal testosterone can have long-term organizational effects on the structure and function of various body systems (e.g., cardiovascular and musculoskeletal systems) that are important for physical activity and exercise.",[26],"Infant Developmental Assessment",[28,29,30,31,32,33],"motor development","sensory processing","2D:4D ratio","digit ratio","infant","Prenatal androgen","RECRUITING","2026-05-04",{"date":37,"type":38},"2026-05-08","ACTUAL",{"date":40,"type":38},"2026-04-06",{"date":42,"type":22},"2027-04-01",{"name":44,"class":45},"Nigde Omer Halisdemir University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":46},"100633824","cortical-tracking-of-speech-in-the-first-year-of-life-100633824","NCT07531706","Cortical Tracking of Speech in the First Year of Life","Cortical Tracking of Speech in the First Year of Life: a Window Into (a)Typical Language Acquisition","Inclusion Criteria:\n\n* Healthy infants aged between 7 and 8 months\n* Infants with and without familial risk for language disorders (Infants are assigned to the group with familial risk for language disorders if at least one first-degree relative had a certified (clinical) diagnosis of language and\u002For learning disorders).\n* Both parents are native-Italian speakers\n\nExclusion Criteria:\n\n* Gestational age \\\u003C 37 weeks and\u002For birth-weight \\\u003C 2500 grams\n* APGAR scores at birth at 1' and 5' \\\u003C 7\n* Bayley Cognitive Score \\\u003C 7\n* Presence of certified diagnosis of intellectual deficiency, attention-deficit disorder, sensorial and neurological disorders or autism within first-degree relatives.","30 Weeks","34 Weeks",{"count":57,"type":22},50,"The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as early predictors of later language development outcomes in infants, including both typical and atypical trajectories.\n\nThe main questions it aims to answer are:\n\n* How do infants with and without a familial history of language and learning impairments differ in their neural ability to track speech and non-speech auditory stimuli at an early stage of development (around 8 months of age)?\n* To what extent do early cortical tracking mechanisms predict later language abilities, including both receptive and expressive skills, measured at approximately 18 months of age? Researchers will compare infants with a familial risk for language and learning impairments (FH+) to infants without such risk (FH-) to determine whether differences in early neural processing of auditory stimuli are associated with later language outcomes.\n\nParticipants will:\n\n* undergo a neurophysiological assessment involving non-invasive electroencephalographic (EEG) recording while being exposed to auditory stimuli, including: speech stimuli (pre-recorded simple stories in Italian, presented in infant-directed speech); non-speech stimuli (musical sounds matched for rhythmic and acoustic properties)\n* take part in a developmental assessment at approximately 8 months of age, including standardized measures of cognitive and early linguistic abilities\n* be involved in a follow-up assessment approximately 10 months later (around 18 months of age), during which standardized tests will evaluate language comprehension and production abilities\n* have additional background information collected, including family history of language and learning disorders and socio-demographic characteristics, to better understand potential risk and protective factors The study follows a longitudinal design and uses non-invasive procedures that do not require active responses from the infant.",[60,61,62,26],"Language Development","Language Development Disorders","Infant Development","2026-04-09",{"date":65,"type":38},"2026-04-15",{"date":67,"type":38},"2025-10-14",{"date":69,"type":22},"2028-02",{"name":71,"class":45},"IRCCS Eugenio Medea"]