[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inferior-alveolar-nerve-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inferior-alveolar-nerve-block":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100568045","the-optimal-injection-site-for-a-3d-guided-inferior-alveolar-nerve-block-device-ianbd-100568045",false,"NCT06676098","The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD)","The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD): A Randomized Control Trial","IANBD","Inclusion Criteria:\n\n* Patient of Henry M. Goldman School of Dentistry (GSDM)\n* Medical History indicating American Society of Anesthesiology (ASA)1\n* Need Non-surgical Endodontic Therapy on Mandibular Molar or Premolar\n* Asymptomatic pulpal diagnosis (normal, necrotic, asymptomatic irreversible pulpitis, retreatment with no symptoms)\n* The quadrant to be treated must have at least 3 vital teeth.\n* Going to receive a CBCT required for clinical purposes\n* Must be willing to receive guided IANB\n\nExclusion Criteria:\n\n* Allergy to lidocaine or articaine\n* Resin allergy\n* Normal teeth unresponsive to thermal testing (ie calcified chamber)\n* Prior jaw surgery\n* Currently pregnant","ALL","18 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","Given the thicker cortical bone in the mandible compared to the maxilla, mandibular teeth cannot be effectively anesthetized via local infiltration anesthesia. Instead, clinicians typically perform regional anesthesia and most commonly, Inferior Alveolar Nerve block (IANB). However, the inferior alveolar nerve is deeply submerged by surrounding structures of bone, muscles, ligaments and vessels. Traditional IANB is a technique by using anatomical landmarks not directly related to Inferior Alveolar Nerve (IAN) to approximate the location of mandibular foramen, where IAN enters mandible. IANB is considered a blind technique and known for the lack of accuracy and precision. The failure rate can be as high as 30-45%. In contrast, the investigator's cone beam computed tomography (CBCT) guided IANB device (IANBD) effectively directs the needle to the mandibular foramen which improves the success rate of the IANB on the first attempt, minimizes injection tissue damage, and reduces patient discomfort.\n\nIn this proof of concept trial, a 3D printed CBCT guided IANBD will be used to administer anesthesia at three injection sites instead of the traditional IANB technique. Participants will be consented patients at the postdoctoral endodontic treatment center, Department of Endodontics, Boston University (BU) Henry M. Goldman School of Dentistry.\n\nThe goal of this research is to to evaluate the acceptability, safety, and effectiveness of guided anesthesia using the IANBD by enrolling 10 subjects who require non-surgical endodontic therapy with a simple, affordable and reliable prototype to be used by clinicians in the dental care setting.",[27],"Inferior Alveolar Nerve Block",[29,30,31,32],"Inferior alveolar nerve block (IANB)","Inferior alveolar nerve block device (IANBD)","3D guided IANBD","Cone beam computed tomography (CBCT)","RECRUITING","2026-01-26",{"date":36,"type":37},"2026-01-27","ACTUAL",{"date":39,"type":37},"2025-12-17",{"date":41,"type":21},"2027-11",{"name":43,"class":44},"Boston University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":45},"100603238","effect-of-ai-supported-child-friendly-communication-on-dental-anxiety-in-pediatric-patients-100603238","NCT07133919","Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients","Evaluation of the Effect of Traditional Behavior Management Techniques and AI-Assisted Child-Friendly Communication on Dental Anxiety in Pediatric Dental Anesthesia Applications","Inclusion Criteria:\n\n* Children volunteers and their parents\u002Flegal guardians who have read and signed the informed consent form and agreed to participate in the study\n* Systemically healthy children aged 6-12 years in the mixed dentition period\n* Children requiring restorative dental procedures (including pulpotomy, pulp capping, or composite restorations) on mandibular teeth under inferior alveolar nerve block local anesthesia\n* Children who are attending their first dental visit and demonstrate behavior rated as 2 (negative) or 3 (positive) according to the Frankl Behavior Rating Scale (Categories: 1 - definitely negative; 2 - negative; 3 - positive; 4 - definitely positive) Behaviors will be categorized as positive (+) or negative (-) based on the Frankl Behavior Rating Scale (Wright's modification)\n* Children receiving local anesthesia for the first time\n\nExclusion Criteria:\n\n* Children volunteers and their parents\u002Flegal guardians who read the informed consent form but declined to participate in the study\n* Children with systemic diseases requiring continuous medication\n* Children with mental or cognitive impairments, as well as those with visual or hearing disabilities\n* Children who, after oral prophylaxis at the first visit, exhibit \"definitely negative\" (Frankl 1) or \"definitely positive\" (Frankl 4) behavior according to the Frankl Behavior Rating Scale\n* Children with previous experience of local anesthesia",true,"7 Years","12 Years",{"count":57,"type":21},60,[24],"This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children aged 6-12. The aim is to evaluate the effectiveness of AI-supported communication tools in reducing anxiety and improving comfort in pediatric dental treatments, potentially enhancing clinical outcomes and advancing technology use in pediatric dentistry.",[61,62,27,63],"Caries, Dental","Local Anesthesia","Dental Anxiety",[65,66,67,68,69],"dental anesthesia","dental anxiety","pediatric dentistry","pediatric patients","inferior alveolar nerve block","2025-12-22",{"date":72,"type":37},"2025-12-24",{"date":74,"type":37},"2025-10-15",{"date":76,"type":21},"2026-01",{"name":78,"class":44},"Çanakkale Onsekiz Mart University",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":45},"100578046","phase-2-warm-versus-conventional-2-lignocaine-for-ianb-efficacy-100578046","NCT06806202","Warm Versus Conventional 2% Lignocaine for IANB Efficacy","Comparative Evaluation of Anesthetic Efficacy of Warm and Conventional 2% Lignocaine for the Success of Inferior Alveolar Nerve Block (IANB) in Mandibular Permanent Molars: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Permanent teeth with acutely inflamed pulp without swelling or draining sinus.\n* Patient who have carious mandibular molars.\n* Patients of either gender aged between 18-50 years old.\n* Systemically healthy patients.\n* Patients who agree to attend for recall appointments and provide a written consent\n\nExclusion Criteria:\n\n* Patients on preoperative analgesics and antibiotics.\n* Teeth with calcified canals and previously treated teeth.\n* Pregnant and lactating mothers.\n* Patients who are immunocompromised, anxious and mentally handicapped.\n* Patients who are allergic to lignocaine.\n* Non-vital or necrosed teeth.","50 Years",{"count":88,"type":21},200,[90],"PHASE2","The study compares the anesthetic efficacy of warm versus conventional 2% lignocaine for inferior alveolar nerve block in mandibular molars, evaluating success rates and onset time.",[93,27],"Success of Inferior Alveolar Nerve Block","2025-01-31",{"date":96,"type":37},"2025-02-03",{"date":98,"type":37},"2024-12-15",{"date":100,"type":21},"2025-03-15",{"name":102,"class":44},"Armed Forces Institute of Dentistry, Pakistan"]