[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"infusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:infusion":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100586074","dexmedetomidine-versus-lidocaine-infusions-as-adjuvants-to-general-anesthesia-for-chronic-pain-management-after-mastectomy-100586074",false,"NCT06910644","Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy","Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 75 years.\n* American Society of Anesthesiologists (ASA) physical status II.\n* Scheduled for mastectomy with axillary dissection (either modified radical mastectomy with or without latissimus dorsi flap or conservative breast surgery) due to breast cancer.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Known allergy to any of the study drugs.\n* Those with hepatic or renal insufficiency.\n* Patients who are running regularly on B blockers.\n* α2 adrenergic agonists and sedatives.\n* Psychoactive medications.","FEMALE","18 Years","75 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare dexmedetomidine and lidocaine infusions as adjuvants to general anesthesia for chronic pain management after mastectomy.",[27,28,29,30,31,32,33],"Dexmedetomidine","Lidocaine","Infusion","Adjuvants","General Anesthesia","Chronic Pain","Mastectomy","RECRUITING","2025-04-05",{"date":37,"type":38},"2025-04-08","ACTUAL",{"date":35,"type":38},{"date":41,"type":21},"2025-12-01",{"name":43,"class":44},"Cairo University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100581319","lidocaine-and-dexmedetomidine-infusions-for-intraoperative-bleeding-in-functional-endoscopic-sinus-surgery-100581319","NCT06848764","Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery","A Randomized Double-Blind Trial Comparing Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Patients Undergoing Functional Endoscopic Sinus Surgery","Inclusion Criteria:\n\n* Age from 18 to 65 years old.\n* American Society of Anesthesiologists (ASA) physical status I - II.\n* Scheduled for elective functional endoscopic sinus surgery.\n\nExclusion Criteria:\n\n* Diabetes mellitus.\n* Coagulation disorders.\n* Kidney and liver dysfunction.\n* Cerebrovascular disease.\n* Cardiovascular problems.\n* High blood pressure.\n* Asthma.\n* Chronic obstructive pulmonary disease (COPD).\n* End organ damage.\n* Psychosis.\n* Taking antipsychotic drugs.\n* Allergy to study drugs.\n* Substance abuse.\n* Taking beta blockers.\n* Heart rate of \\\u003C 55 beat\u002Fminute.","ALL","65 Years",{"count":56,"type":21},40,[24],"This work aims to compare lidocaine and dexmedetomidine infusions for intraoperative bleeding in patients undergoing functional endoscopic sinus surgery.",[28,27,29,60,61],"Intraoperative Bleeding","Functional Endoscopic Sinus Surgery","2025-03-01",{"date":64,"type":38},"2025-03-05",{"date":62,"type":38},{"date":67,"type":21},"2025-09-01",{"name":69,"class":44},"Ain Shams University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":53,"minAge":17,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":88,"leadSponsor":90,"locationsCount":45},"100580455","lidocaine-and-dexmedetomidine-infusion-and-their-combination-on-perioperative-pain-in-patients-undergoing-video-assisted-thoracoscopic-surgery-100580455","NCT06837519","Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery","A Randomized Double-Blind Trial Comparing Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery","Inclusion Criteria:\n\n* Age ≥18 years old.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status of I, II.\n* Patients undergoing video-assisted thoracoscopic surgery (VATS) under general anesthesia.\n\nExclusion Criteria:\n\n* Hypersensitivity to any of the used drugs.\n* Coagulation disorder.\n* Body mass index \\>35 kg\u002Fm2.\n* History of chronic pain requiring daily opioids\u002Fsteroids\u002Fclonidine\u002Fother α2 agonist\u002Fanalgesics or any drugs acting on the central nervous system during the previous 2 weeks, and drug\u002Falcohol abuse.\n* Contraindication to the use of local anesthetics.\n* Cardiovascular disease.\n* Severe respiratory, renal or hepatic impairment.\n* Insulin-dependent diabetes mellitus.\n* Central nervous system or psychiatric disease.",{"count":78,"type":21},75,[24],"This study aims to compare lidocaine and dexmedetomidine infusion and their combination on perioperative pain in patients undergoing video-assisted thoracoscopic surgery.",[28,27,29,82,83],"Perioperative Pain","Video-Assisted Thoracoscopic Surgery","2025-02-20",{"date":86,"type":38},"2025-02-21",{"date":84,"type":38},{"date":89,"type":21},"2025-08-01",{"name":69,"class":44}]