[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inguinal-hernia-repair\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inguinal-hernia-repair":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,45,72,99,123,149,178,201,223],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100632290","comparison-of-laryngeal-mask-airway-versus-endotracheal-intubation-in-pediatric-laparoscopic-inguinal-hernia-repair-100632290",false,"NCT07511764","Comparison of Laryngeal Mask Airway Versus Endotracheal Intubation in Pediatric Laparoscopic Inguinal Hernia Repair","Comparison of Laryngeal Mask Airway Versus Endotracheal Intubation in Pediatric Laparoscopic Inguinal Hernia Repair: A Multicenter, Prospective, Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* being between 1 and 10 years of age,\n* having a planned laparoscopic inguinal hernia repair,\n* being classified as ASA I-II,\n* having given informed consent from the parent.\n\nExclusion Criteria:\n\n* Obesity (body weight \\>95th percentile),\n* symptomatic gastroesophageal reflux,\n* high risk of aspiration,\n* upper airway anomalies,\n* history of difficult intubation,\n* acute respiratory tract infection,\n* emergency surgical indication,\n* need for conversion from laparoscopy to open surgery,\n* presence of additional systemic risks such as immunodeficiency\u002Fmalignancy.","ALL","1 Year","10 Years",{"count":20,"type":21},266,"ESTIMATED","INTERVENTIONAL",[24],"NA","Inguinal hernia is one of the most common conditions requiring surgical intervention in childhood, with a reported lifetime prevalence of 1-4%. With the increasing use of minimally invasive techniques such as PIRS (Percutaneous Internal Ring Suturing) among laparoscopic surgical procedures, perioperative anesthesia and airway management have become a critical area of clinical decision-making. The traditional approach in pediatric laparoscopic surgery is endotracheal intubation (ETT). Although ETT provides reliable airway control, it carries certain disadvantages. In contrast, the laryngeal mask airway (LMA) is less invasive and is associated with faster recovery. Systematic reviews and meta-analyses conducted in recent years have shown that the LMA may be safe for ventilation in pediatric laparoscopy, reduces peak airway pressure, and shortens recovery time. No well-designed, multicenter study with an adequate sample size comparing the LMA and ETT in pediatric laparoscopic inguinal hernia surgery has yet been conducted. This gap limits evidence-based decision-making in a clinical setting that directly impacts practice. Therefore, the aim of this study is to compare LMA and ETT in pediatric laparoscopic inguinal hernia repair. In this regard, the study is unique and necessary from both clinical and academic perspectives for determining the optimal airway strategy in pediatric laparoscopy.",[27],"Inguinal Hernia Repair",[29,30,31],"inguinal hernia","laparoscopy","laryngeal mask airway","RECRUITING","2026-06-19",{"date":35,"type":36},"2026-06-24","ACTUAL",{"date":38,"type":36},"2025-12-01",{"date":40,"type":21},"2026-09-15",{"name":42,"class":43},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100640361","transrectus-sheath-preperitoneal-procedure-trepp-for-inguinal-hernia-repair-100640361","NCT07618884","TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair","TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study.","Inclusion Criteria:\n\n* Adults with primary unilateral or bilateral inguinal hernia\n\nExclusion Criteria:\n\n* Strangulated hernias.\n* Severe comorbidities precluding surgery ((ASA Class IV,V)","18 Years",{"count":54,"type":21},30,[24],"Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role.\n\nThe trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.",[58,27],"Inguinal Hernia",[60,61,62],"Inguinal hernia","Chronic postoperative inguinal pain","Trans rectus sheath extra-peritoneal procedure","2026-05-28",{"date":65,"type":36},"2026-06-01",{"date":67,"type":36},"2025-04-15",{"date":69,"type":21},"2026-09",{"name":71,"class":43},"Assiut University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":79,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":95,"leadSponsor":97,"locationsCount":4},"100639001","perioperative-safety-and-long-term-outcomes-of-mesh-repair-in-nonagenarians-undergoing-elective-inguinal-hernia-repair-100639001","NCT07602647","Perioperative Safety and Long-Term Outcomes of Mesh Repair in Nonagenarians Undergoing Elective Inguinal Hernia Repair","Perioperative Safety and Long-Term Outcomes of Mesh Repair in Nonagenarians Undergoing Elective Inguinal Hernia Repair: A Single-Center Retrospective Cohort Study","Inclusion Criteria: patients aged 90 years or older who underwent elective inguinal hernia repair -\n\nExclusion Criteria: Patients underwent emergency surgery for incarcerated or strangulated hernia. Patients were also excluded if incomplete data, or valid follow-up information was unavailable.\n\n\\-","90 Years",{"count":81,"type":21},150,"OBSERVATIONAL","To evaluate the clinical characteristics, postoperative outcomes, and factors associated with Clavien-Dindo grade ≥II complications in nonagenarians undergoing elective inguinal hernia repair. Preoperative, intraoperative, and postoperative data of nonagenarians who underwent elective inguinal hernia repair were collected. The primary outcome was Clavien-Dindo grade ≥II complications. Univariable logistic regression was used to identify associated factors.",[27],[60,86,87,88,89],"nonagenarians","Clavien-Dindo classification","functional status","mesh repair","NOT_YET_RECRUITING","2026-05-16",{"date":93,"type":36},"2026-05-22",{"date":65,"type":21},{"date":96,"type":21},"2026-06-15",{"name":98,"class":43},"Fudan University",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":22,"phases":107,"briefSummary":108,"conditions":109,"keywords":112,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":44},"100587913","de-implementation-of-low-value-testing-in-patients-undergoing-low-risk-surgery-100587913","NCT06934564","De-Implementation of Low-value Testing in Patients Undergoing Low-Risk Surgery","Site\n\nInclusion Criteria:\n\n* Over 30% of testing rates on at least one of the three index procedures (breast lumpectomy, laparoscopic cholecystectomy, and inguinal hernia repair)\n\nExclusion Criteria:\n\n* none\n\nSurgical participants must be over 18 years old.",{"count":106,"type":21},16,[24],"This trial aims to evaluate the effectiveness of a multi-level, multi-component de-implementation strategy to reduce unnecessary preoperative testing. Sixteen Michigan Value Collaborative (MVC)\u002FMichigan Surgical Quality Collaborative (MSQC) sites in Michigan will implement several tools that have been proven to reduce unnecessary testing at a single site, including clinician education, a decision aid, audit and feedback on performance, and a pay-for-performance incentive. The researchers believe that, through the use of these strategies, there will be a significant reduction in unnecessary preoperative testing during the intervention.",[110,111,27],"Breast Lumpectomy","Laparoscopic Cholecystectomy",[113],"Preoperative testing","2026-05-05",{"date":116,"type":36},"2026-05-08",{"date":118,"type":36},"2025-04-01",{"date":120,"type":21},"2026-12",{"name":122,"class":43},"University of Michigan",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":130,"sex":16,"minAge":52,"maxAge":131,"enrollmentInfo":132,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":146,"leadSponsor":148,"locationsCount":4},"100630713","mesh-infection-after-hernioplasty-complete-vs-partial-removal---retrospective-study-on-outcomes-and-pathogen-analysis-100630713","NCT07491250","Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis","A Retrospective Study: Complete vs Partial Mesh Removal for Mesh Infection After Hernioplasty - Clinical Outcomes and Pathogen Analysis","Inclusion Criteria:\n\n1. Patients who underwent tension-free inguinal hernioplasty with mesh placement.\n2. Patients diagnosed with mesh infection requiring surgical re-intervention.\n3. Patients who underwent complete or partial mesh removal surgery.\n4. Availability of complete medical records and follow-up data.\n\nExclusion Criteria:\n\n1. Patients with mesh infection managed conservatively (without surgical removal).\n2. Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up).\n3. Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair).\n4. Patients lost to follow-up immediately after discharge (no postoperative assessment).",true,"80 Years",{"count":133,"type":21},100,"Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients.\n\nMaterials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.",[27,136],"Mesh Infection",[138,139,140,141],"Inguinal hernia repair","mesh infection","complete mesh removal","partial mesh removal","2026-03-18",{"date":144,"type":36},"2026-03-24",{"date":142,"type":21},{"date":147,"type":21},"2026-07-31",{"name":98,"class":43},{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":131,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":163,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":44},"100613293","visually-guided-tap-block-in-laparoscopic-tapp-hernia-repair-100613293","NCT07264699","Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair","Efficacy of Visually Guided Transversus Abdominis Plane (TAP) Block in Recovery After Laparoscopic Inguinal Hernia Repair (TAPP - Transabdominal Preperitoneal)","VIS-TAP-TAPP","Inclusion Criteria:\n\n* Age 18-80 years\n* Elective laparoscopic inguinal hernia repair using the TAPP (Transabdominal Preperitoneal) technique\n* ASA physical status I-III\n* Ability to provide written informed consent\n* No contraindications to regional anesthesia or local anesthetic administration\n\nExclusion Criteria:\n\n* Recurrent or strangulated inguinal hernia\n* Emergency surgery\n* Chronic pain syndromes or preoperative opioid use\n* Known allergy or hypersensitivity to local anesthetics (bupivacaine or similar)\n* Severe hepatic or renal impairment\n* Psychiatric disorders or inability to provide informed consent\n* Conversion to open surgery during the procedure\n* Technical difficulties preventing TAP block administration",{"count":133,"type":21},[24],"This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after laparoscopic inguinal hernia repair using the TAPP (Transabdominal Preperitoneal) technique.\n\nThe study will enroll 100 adult patients undergoing elective laparoscopic TAPP hernia repair at the University Clinical Hospital in Olsztyn, Poland. Participants will be randomly assigned to two equal groups. In the study group, a bilateral TAP block will be performed under direct vision using 20 ml of 0.25% bupivacaine on each side after establishing pneumoperitoneum. The control group will undergo the same surgical procedure without the TAP block.\n\nAll patients will receive standardized anesthesia and postoperative pain management according to hospital protocol. Postoperative pain intensity will be assessed using the Visual Analogue Scale (VAS) at 0, 6, and 12 hours after surgery. Additional data, such as time to mobilization, use of rescue analgesics, and occurrence of postoperative complications (hematoma, swelling, subcutaneous emphysema, transient muscle weakness), will also be recorded.\n\nThe primary goal of this study is to determine whether a laparoscopically guided TAP block can effectively reduce postoperative pain and improve recovery parameters following TAPP hernia repair. The results may help establish a simple, safe, and reproducible method of multimodal analgesia in minimally invasive inguinal hernia surgery.",[27,161,162],"Postoperative Pain","TAP Block",[60,164,165,166,167,168],"TAPP","Laparoscopic hernia repair","TAP block","Transversus abdominis plane block","Multimodal analgesia","2026-03-15",{"date":171,"type":36},"2026-03-17",{"date":173,"type":36},"2025-12-04",{"date":175,"type":21},"2027-03",{"name":177,"class":43},"University of Warmia and Mazury in Olsztyn",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":182,"acronym":183,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":16,"minAge":185,"maxAge":4,"enrollmentInfo":186,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":188,"conditions":189,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":200},"100606924","robotic-minimally-invasive-inguinal-hernia-repair-post-market-clinical-study-with-the-dexter-robotic-system-100606924","NCT07181876","Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System","RAS-ACCESS","Inclusion Criteria:\n\n* Subject is ≥ 22 years of age at time of enrollment\u002Fconsent\n* Subject is indicated for and planned to undergo robot-assisted and laparoscopic surgery for unilateral or bilateral inguinal hernia repair\n* Subject is able and willing to comply with the protocol requirements, has been informed of the nature of the study, and has signed the IRB-approved informed consent form\n\nExclusion Criteria:\n\n* Subject with any relative and absolute contraindications for the use of conventional endoscopes and endoscopic surgical instruments and\u002For general non-procedure specific contraindications to endoscopic surgery including bleeding diathesis and pregnancy\n* Subject is participating in another clinical investigation at the time of enrollment or planned participation at any time during this clinical study\n* Subject has a known or suspected medical condition that, in the opinion of the Investigator, may put the subject at risk for participation in this clinical study","22 Years",{"count":187,"type":21},140,"The purpose of this post-market, observational study is to collect data under anticipated conditions of use that demonstrates that DEXTER performs as intended in the intended patient population, including a variety of representative disease etiologies and demographic groups.",[27],"2026-01-21",{"date":192,"type":36},"2026-01-22",{"date":194,"type":36},"2025-11-26",{"date":196,"type":21},"2029-12",{"name":198,"class":199},"Distalmotion SA","INDUSTRY",2,{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":4,"eligibilityCriteria":207,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":208,"enrollmentInfo":209,"targetDuration":4,"studyType":22,"phases":211,"briefSummary":212,"conditions":213,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":4},"100621645","modified-vs-conventional-laparoscopic-tapp-for-inguinal-hernia-100621645","NCT07373314","Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia","A Randomized Controlled Trial Comparing Modified Tumescent vs. Conventional Laparoscopic TAPP for Inguinal Hernia Repair","Inclusion Criteria:\n\n* Age: 18 to 50 years.\n* Gender: Both male and female participants.\n* Condition: Diagnosed with unilateral inguinal hernia (as per operational definition).\n* Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery.\n* Consent: Participants must be able to provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Femoral Hernias.\n* Incarcerated or Strangulated Hernia.\n* Recurrent Hernias (as per medical record).\n* Serious Systemic Diseases:\n* Conditions such as heart failure or coagulation problems (e.g., PT \\> 15 sec).\n* ASA III-V classification, indicating a higher risk for surgery.\n* Pregnancy (if applicable).\n* Allergy to Anesthesia or the substances used in the tumescent solution (lidocaine, epinephrine, saline).\n* Uncontrolled Diabetes or other medical conditions that might interfere with the healing process.","50 Years",{"count":210,"type":21},60,[24],"This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.",[27],"2026-01-19",{"date":216,"type":36},"2026-01-28",{"date":218,"type":21},"2026-02-10",{"date":220,"type":21},"2026-08-30",{"name":222,"class":43},"University of Health Sciences Lahore",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":230,"minAge":231,"maxAge":52,"enrollmentInfo":232,"targetDuration":4,"studyType":22,"phases":234,"briefSummary":235,"conditions":236,"keywords":237,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":44},"100612393","comparison-of-outcomes-of-hernia-sac-transection-and-sac-reduction-in-open-pediatric-inguinal-hernia-repair-in-ramathibodi-hospital-100612393","NCT07252999","Comparison of Outcomes of Hernia Sac Transection and Sac Reduction in Open Pediatric Inguinal Hernia Repair in Ramathibodi Hospital","Transection Versus Reduction of Hernia Sac in Open Pediatric Inguinal Hernia Repair: A Randomized Controlled Trial Study","Inclusion Criteria:\n\n* Male pediatric patients under 18 years old\n* Patients who underwent open inguinal hernia surgery on the affected side by a pediatric surgeon\n* Patients who had follow-up after inguinal hernia surgery at Ramathibodi Hospital or phone follow-up (Telemed) for 6 months\n* Patients who agree to participate in the study by signing an informed consent form\n\nExclusion Criteria:\n\n* Preterm infants\n* Inguinal hernia patients with strangulated hernia\n* Patients with non-communicating hydrocele\n* Patients who had follow-up at another hospital after inguinal hernia surgery\n* Patients who refused to participate in the study or withdrawn","MALE","1 Day",{"count":233,"type":21},40,[24],"The goal of this clinical trial is to learn if hernia sac transection works to treat pediatric inguinal hernia. Researchers will compare hernia sac transection to hernia sac reduction (traditional inguinal hernia repair) to see outcome in 6 months. Visit the clinic at week1, month3, month 6 for follow-up.",[27],[238,239,240],"hernia sac transection","hernia sac reduction","open inguinal hernia repair","2025-11-24",{"date":243,"type":36},"2025-11-28",{"date":245,"type":36},"2025-10-31",{"date":247,"type":21},"2027-12-31",{"name":249,"class":43},"Piyanuch Lormuangthong"]