[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inguinal-hernia-unilateral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inguinal-hernia-unilateral":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,50,93,117,148,176,209,238],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100632151","effect-of-preoperative-erector-spinae-plane-block-on-recovery-quality-time-to-return-to-daily-activities-and-postoperative-pain-scores-in-inguinal-hernia-surgery-100632151",false,"NCT07509957","Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery","ESPB for IHR","Inclusion Criteria:\n\n1. Patients aged between 18 and 65 years\n2. Patients scheduled to undergo open IHT surgery under spinal anesthesia (unilateral)\n3. Both male and female patients\n\nExclusion Criteria:\n\n1. Patients with coagulation disorders\n2. Patients with chronic opioid use\n3. Patients who develop intraoperative complications\n4. Patients with a preoperative Numeric Rating Scale (NRS) pain score ≥4\n5. Patients with a history of revision (recurrent) surgery\n6. Patients unable to communicate for any reason\n7. Patients who decline to participate in the study","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal hernia repair under spinal anesthesia.\n\nPostoperative pain following inguinal hernia surgery may delay recovery and negatively affect patients' return to normal daily life. Although ESPB has been widely used as an effective analgesic technique in various surgical procedures, its effectiveness in inguinal hernia repair remains limited and not well established.\n\nIn this randomized controlled study, patients will be divided into two groups: one group will receive ESPB after surgery, while the control group will not receive any block. All patients will receive standard postoperative analgesia.\n\nQuality of recovery, acute pain scores, and analgesic consumption will be assessed within the first 24 hours after surgery, and return to daily activities will be evaluated 30 days after surgery.\n\nThe primary outcome of this study is quality of recovery assessed using the Quality of Recovery-15 (QoR-15) questionnaire. QoR-15 scores range from 0 to 150, with higher scores indicating better recovery. Scores will be recorded preoperatively and 24 hours after surgery.\n\nSecondary outcomes include postoperative pain intensity, total opioid consumption, and time to return to daily activities. Pain intensity will be assessed using the Numeric Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst pain imaginable, at 15, 30, 60, and 120 minutes, as well as 6, 12, and 24 hours after surgery.\n\nTotal opioid consumption will be determined by recording the cumulative dose of intravenous tramadol administered as rescue analgesia within the first 24 hours after surgery. Time to return to daily activities will be evaluated via telephone follow-up 30 days after surgery.",[27,28,29,30,31],"Inguinal Hernia Unilateral","Erector Spinae Plane Block","Quality of Recovery (QoR-15)","Numeric Rating Scale","Return to Daily Activity",[33,28,34,35,31,36],"Inguinal Hernia Repair","Regionel Anesthesia","Quality of Recovery","Postoperative Pain","RECRUITING","2026-07-01",{"date":40,"type":41},"2026-07-02","ACTUAL",{"date":43,"type":41},"2026-04-04",{"date":45,"type":21},"2026-07-16",{"name":47,"class":48},"Sanliurfa Education and Research Hospital","OTHER_GOV",2,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":92},"100643499","phase-1-reversing-inguinal-hernia-trial-the-evaluation-of-sex-hormones-to-reverse-inguinal-hernias-in-males-100643499","NCT07604272","Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males","Reversing InGuinal Hernia Trial (RIGHT Trial): The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males","RIGHT","Inclusion Criteria:\n\n* Male sex\n* Age ≥ 50 years at time of enrollment\n* Symptomatic unilateral inguinal hernia confirmed on physical examination\n* Hernia visible \u002F confirmed on groin ultrasound\n* Non-recurrent inguinal hernia (primary hernia only)\n* Willing and able to provide written informed consent\n* Able and willing to comply with all protocol-required visits, laboratory assessments, imaging, and follow-up\n* Willing to use contraception and avoid fathering a child during study participation and for 12 months after last dose\n* Willing to be counseled regarding vitamin D and calcium supplementation Bone safety mitigation measure per PIND response.\n\nExclusion Criteria:\n\nHernia Characteristics\n\n* Scrotal hernia (any)\n* Bilateral inguinal hernia\n* Recurrent inguinal hernia (prior repair at same site)\n\nRenal \\& Hepatic\n\n* Clinically significant renal dysfunction judged by investigator to increase study risk\n* Clinically significant hepatic dysfunction at baseline\n\nHematologic\n\n■ Clinically significant baseline hematologic abnormality (including elevated hematocrit or polycythemia)\n\nUrologic \u002F Prostate\n\n* Symptomatic benign prostatic hyperplasia (BPH) requiring active medical or procedural treatment\n* Clinically significant untreated prostate disease\n\nSkeletal \u002F Bone\n\n* Baseline osteoporosis (T-score ≤ -2.5 on DEXA at any site)\n* Recent fragility fracture (within prior 12 months or as judged by investigator)\n* Other clinically significant skeletal vulnerability judged to increase risk from estrogen suppression\n\nImmunosuppression ■ Active immunosuppression (e.g., systemic corticosteroids, biologic agents, post-transplant regimens)\n\nPsychiatric\n\n■ Unstable or uncontrolled psychiatric illness that, in the investigator's judgment, would interfere with safe study participation\n\nReproductive \u002F Fertility ■ Actively pursuing fertility or planning conception during study participation\n\nPrior \u002F Concomitant Therapy\n\n* Current use of androgen replacement therapy, exogenous estrogen, or other endocrine-active agents that would confound study interpretation\n* Prior or current use of aromatase inhibitor or selective estrogen receptor modulator \u002F degrader within 6 months of enrollment\n\nGeneral\n\n■ Any other clinically significant medical condition, laboratory abnormality, or circumstance that, in the investigator's judgment, would place the participant at unacceptable risk or compromise study integrity","MALE","50 Years",{"count":61,"type":21},30,[63],"PHASE1","This is a prospective, single-center, three-arm Phase 1 safety and feasibility trial evaluating anti-estrogen therapy in men age 50 years and older with symptomatic unilateral inguinal hernias. Participants will be randomized to receive fulvestrant 250 mg intramuscularly, fulvestrant 500 mg intramuscularly, or letrozole 5 mg orally for 6 months. The study will evaluate safety, tolerability, feasibility, hormone changes, hernia size, patient-reported outcomes, bone density, and imaging-based hernia classification.",[27,66,67,68],"Inguinal Hernia Bilateral","Inguinal Hernia Without Obstruction or Gangrene","Inguinal Hernia, Without Mention of Obstruction or Gangrene",[70,71,72,73,74,75,76,77,78,79,80,81,82],"inguinal hernia","hernia","fulvestrant","letrozole","anti-estrogen therapy","aromatase inhibitor","estrogen receptor","ESR1","male inguinal hernia","hormonal therapy","fibrosis","hernia prevention","hernia regression","2026-06-24",{"date":85,"type":41},"2026-06-26",{"date":38,"type":21},{"date":88,"type":21},"2028-06",{"name":90,"class":91},"Northwestern University","OTHER",1,{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":22,"phases":103,"briefSummary":104,"conditions":105,"keywords":106,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":111,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":92},"100628432","watchful-waiting-versus-immediate-repair-for-occult-contralateral-inguinal-hernias-100628432","NCT07461558","Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.","WATCH IT TRIAL WAtchful Waiting Versus immediaTe Repair for Occult Contralateral Hernias Found During MIS Inguinal Hernia Repair Trial.","WATCH IT","Inclusion Criteria:\n\n* Male or female patients ≥18 years old\n* Symptomatic unilateral inguinal hernia\n* Occult contralateral hernia identified intraoperatively\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Prior contralateral inguinal hernia repair\n* Symptomatic, bilateral inguinal hernias confirmed on physical exam\n* Contraindications to general anesthesia or surgery\n* Urgent or emergent presentations\n* Adults unable to consent\n* Pregnant patients",{"count":102,"type":21},380,[24],"This study will compare two ways of managing a small, hidden hernia that can sometimes be found during minimally invasive surgery to repair a hernia on one side of the groin. Occasionally while fixing the known hernia, the surgeon discovers a small hernia on the other side that has not caused any symptoms. Surgeons do not agree on the best way to handle these hernias. Some believe it should be repaired right away during the same operation to prevent it from getting bigger or from causing symptoms later, which could require another surgery. Others believe it is better to leave it alone since it is not causing problems and groin hernia surgery carries risks including long-term pain.\n\nThis study will randomly assign patients, if a hidden hernia is found during surgery, to either having it repaired immediately or to have it monitored over time. Patients will be followed up at 30 days, 1 year and 2 years following surgery. The researchers will compare recovery and quality of life between the two groups. For those in the monitoring group, the study will also track whether the hidden hernia causes symptoms or eventually needs surgery. The goal is to determine whether repairing the hidden hernia right away is as safe and effective as watching and waiting, so doctors and patients can make more informed decisions in the future.",[66,27],[107,108,109,110],"Occult inguinal hernia","Asymptomatic inguinal hernia","Minimally invasive inguinal hernia repair","Transabdominal preperitoneal inguinal hernia repair",{"date":85,"type":41},{"date":113,"type":41},"2026-04-01",{"date":115,"type":21},"2029-04",{"name":90,"class":91},{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":22,"phases":128,"briefSummary":129,"conditions":130,"keywords":134,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":4},"100611303","transversalis-fascia-plane-block-versus-surgical-wound-infiltration-for-postoperative-analgesia-in-open-inguinal-hernia-repair-100611303","NCT07238829","Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair","Analgesic Efficacy of Ultrasound-Guided Transversalis Fascia Plane Block Versus Surgical Wound Infiltration After Open Inguinal Hernia Surgery: A Randomized Controlled Trial","TFPB-WIN","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for elective unilateral open inguinal hernia repair\n* Planned anesthesia: spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Able to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\> 35 kg\u002Fm²\n* Known hypersensitivity to local anesthetics used in the study (e.g., bupivacaine) or to analgesic medications\n* Coagulopathy\n* Infection or hematoma at the planned block site\n* Significant systemic disease (such as chronic kidney disease, hepatic failure, chronic obstructive pulmonary disease, etc.)\n* History of chronic pain or long-term analgesic use\n* Inability to use the patient-controlled analgesia system\n* Presence of psychiatric disorders\n* Refusal to participate in the study.\n* Cases with a surgical duration shorter than 30 minutes or longer than 180 minutes were excluded.","80 Years",{"count":127,"type":21},104,[24],"The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in adult patients undergoing open inguinal hernia repair.\n\nThe key questions that this study aims to answer are:\n\nDoes TFPB reduce total intravenous opioid consumption within the first 24 postoperative hours compared with wound infiltration?\n\nDoes TFPB improve postoperative pain scores at rest and during movement compared with wound infiltration?\n\nDoes TFPB improve patient satisfaction, reduce the need for rescue analgesics, and enhance overall postoperative recovery quality?\n\nIf there is a comparison group:\n\nThe investigators will compare the effects of TFPB with wound infiltration to determine whether either technique provides superior postoperative analgesia and reduces opioid requirements.\n\nParticipants will be asked to:\n\nUndergo open inguinal hernia repair under spinal anesthesia.\n\nBe randomly assigned to one of two groups:\n\nTFPB Group: Receive an ultrasound-guided transversalis fascia plane block with local anesthetic.\n\nWound Infiltration Group: Receive local anesthetic infiltration performed by the surgeon along the incision line.\n\nPostoperatively:\n\nReport pain scores at defined intervals.\n\nReceive standardized IV analgesia with documentation of opioid consumption.\n\nAllow assessment of rescue analgesic requirement.\n\nBe monitored for adverse events and recovery outcomes.",[27,131,132,133],"Postoperative Pain Management","Regional Anaesthesia","Transversalis Fascia Plane Block",[135,136,70,137],"transversalis fascia plane block","regional anaesthesia","analgesia","NOT_YET_RECRUITING","2026-06-20",{"date":141,"type":41},"2026-06-25",{"date":143,"type":21},"2027-01-01",{"date":145,"type":21},"2027-04-01",{"name":147,"class":91},"Ondokuz Mayıs University",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":92},"100638559","intravenous-lidocaine-for-postoperative-fatigue-after-laparoscopic-tapp-inguinal-hernia-repair-100638559","NCT07612839","Intravenous Lidocaine for Postoperative Fatigue After Laparoscopic TAPP Inguinal Hernia Repair","The Effect of Intravenous Lidocaine on Postoperative Fatigue Syndrome in Patients Undergoing Elective Laparoscopic TAPP Inguinal Hernia Repair","LIDO-TAPP","Inclusion Criteria:\n\nAdult patients aged 18 years and older Patients scheduled for elective laparoscopic TAPP inguinal hernia repair under general anesthesia ASA physical status I-II Patients who provide written informed consent -\n\nExclusion Criteria:\n\nModerate to severe hepatic dysfunction Low cardiac output or severe heart failure Severe cardiac conduction abnormalities or clinically significant arrhythmias Planned concomitant use of high-dose local anesthetics, including infiltration or regional block Advanced age or frailty Pregnancy or breastfeeding Known allergy or contraindication to lidocaine Refusal to participate in the study\n\n\\-",{"count":157,"type":21},80,[24],"This prospective randomized controlled study aims to evaluate the effect of perioperative intravenous lidocaine infusion on postoperative fatigue syndrome in patients undergoing elective laparoscopic TAPP inguinal hernia repair. Participants will be randomly assigned to receive either intravenous lidocaine infusion or standard perioperative management without lidocaine. The primary objective is to assess postoperative fatigue and recovery quality. Secondary outcomes include postoperative pain, analgesic consumption, nausea-vomiting, mobilization time, and length of hospital stay.",[161,27],"Postoperative Fatigue Syndrome",[163,164,165,166],"Intravenous Lidocaine","Postoperative Fatigue","Laparoscopic TAPP Repair","Postoperative Recovery","2026-05-21",{"date":169,"type":41},"2026-05-29",{"date":171,"type":21},"2026-06-05",{"date":173,"type":21},"2026-09-10",{"name":175,"class":91},"Hakan Emirkadı",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":184,"enrollmentInfo":185,"targetDuration":4,"studyType":22,"phases":186,"briefSummary":187,"conditions":188,"keywords":190,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":205,"leadSponsor":207,"locationsCount":92},"100618213","postoperative-ozonated-oil-dressing-after-open-inguinal-hernia-repair-a-randomized-pilot-trial-100618213","NCT07328698","Postoperative Ozonated Oil Dressing After Open Inguinal Hernia Repair: A Randomized Pilot Trial","Effect of Postoperative Ozonated Oil Dressing on Early Wound Inflammation After Open Mesh Inguinal Hernia Repair: A Prospective Randomized Pilot Controlled Trial","OZONE-HERNIA","Inclusion Criteria:\n\n* Adults aged 18 to 75 years\n* ASA physical status I-III\n* Scheduled for elective, unilateral open inguinal hernia repair\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Emergency inguinal hernia (incarcerated or strangulated)\n* Recurrent inguinal hernia\n* Concomitant surgical procedures during the same operation\n* Immunosuppression or long-term systemic steroid use\n* Use of anticoagulant or antiplatelet therapy\n* Known bleeding disorders\n* Active dermatologic disease at the surgical incision site\n* Pregnancy","75 Years",{"count":20,"type":21},[24],"This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common operation, and although infection rates are low, many patients experience redness, swelling, tenderness, or discomfort at the surgical site during the first days after surgery.\n\nParticipants undergoing elective open inguinal hernia repair will be randomly assigned to receive either an ozonated oil-impregnated dressing or a standard sterile dressing after the operation. The main outcome is the level of wound inflammation measured on the third day after surgery. Other outcomes include wound temperature, pain levels, cosmetic healing, and wound-related problems during the first 30 days.\n\nThe ozonated oil used in this study is a CE-certified medical product that is already used in routine wound care. This pilot study aims to provide preliminary data to help determine whether ozonated oil dressing may improve early wound healing compared with standard care.",[27,189],"Postoperative Wound Inflammation",[191,192,193,194,195,196,197,198,199,200],"Inguinal hernia repair","Open inguinal hernia surgery","Ozonated oil","Ozonated oil dressing","Postoperative wound inflammation","Surgical wound care","Topical ozone","Pilot randomized controlled trial","Clean surgical wound","Wound surface temperature","2026-02-10",{"date":203,"type":41},"2026-02-11",{"date":201,"type":41},{"date":206,"type":21},"2026-05-31",{"name":208,"class":91},"Nigde Omer Halisdemir University",{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":4,"eligibilityCriteria":215,"healthyVolunteers":216,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":217,"targetDuration":4,"studyType":22,"phases":218,"briefSummary":219,"conditions":220,"keywords":225,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":92},"100584827","comparison-the-analgesic-efficacy-of-ultrasonographic-bilateral-tap-and-anesthetic-infiltration-into-the-surgery-field-for-laparoscopic-unilateral-tep-herniorrhaphy-100584827","NCT06894420","Comparison the Analgesic Efficacy of Ultrasonographic Bilateral TAP and Anesthetic Infiltration Into the Surgery Field for Laparoscopic Unilateral TEP Herniorrhaphy","Comparison of Postoperative Analgesic Efficacy of Ultrasonographic Bilateral TAP (Transversus Abdominis Plane) Block and Anesthetic Infiltration Into Preperitoneal and the Surgical Field in Laparoscopic Unilateral TEP (Total Extraperitoneal) Herniorraphy","Inclusion Criteria:\n\n* Consenting patients,\n* She will undergo laparoscopic hernia repair surgery,\n* ASA-I-II,\n* Between the ages of 18 and 65,\n* No history of anticoagulant or antiaggregant drug use,\n* Regional anesthesia is not contraindicated and the anesthesiologist deems -appropriate for regional anesthesia,\n* Under general anesthesia and will undergo laparoscopic surgery,\n* Fully oriented and cooperative,\n* Unilateral inguinal hernia,\n* No previous surgery for inguinal hernia,\n* No incision in the lower abdomen,\n* Not using alcohol and drugs,\n* No preoperative pain and\n* Patients without symptoms of strangulated hernia will be included in the study.\n\nExclusion Criteria:\n\n* Patients without consent\n* Regional anesthesia is contraindicated,\n* Those who will undergo open abdominal surgery,\n* Not in the appropriate age range,\n* Chronic diseases such as uncontrolled DM and HT,\n* Drug allergy,\n* Taking anticoagulant or antiaggregant drugs,\n* History of chronic analgesic use,\n* Presence of active infection in the area to be blocked,\n* Will not be able to comply with postoperative pain \u002FVAS follow-up,\n* Patients with ASA-III-IV,\n* Patients with bilateral inguinal and scrotal hernias,\n* Patients who have been previously operated for inguinal hernia and have an incision in the lower abdomen,\n* Those with a history of alcohol and drug abuse\n* Preoperative pain and\n* Those with symptoms of strangulated hernia will not be included in this study.",true,{"count":20,"type":21},[24],"Laparoscopic inguinal hernia repair is a common surgical procedure, but postoperative pain management remains a challenge. This prospective, randomized study aims to compare the analgesic efficacy of preperitoneal and surgical site anesthetic infiltration with ultrasound-guided bilateral transversus abdominis plane (TAP) block in patients undergoing laparoscopic unilateral total extraperitoneal (TEP) herniorrhaphy. Sixty patients will be randomly allocated into two groups: Group-I will receive preperitoneal and surgical site infiltration with bupivacaine, while Group-II will receive ultrasound-guided bilateral TAP block with bupivacaine. The primary outcomes will be postoperative pain scores assessed using the visual analog scale (VAS) and additional analgesic requirements. Secondary outcomes will include postoperative hospital stay duration and cost-effectiveness. Demographic data, ASA scores, comorbidities, and operation times will be recorded. Postoperative pain will be managed with a multimodal approach, including paracetamol and NSAIDs. Rescue analgesia will be provided with intravenous paracetamol. Statistical analysis will be performed using t-tests, ANOVA, Wilcoxon-Mann-Whitney tests, and chi-square tests, as appropriate. This study aims to determine the optimal and most beneficial method for postoperative pain management and patient comfort following laparoscopic inguinal hernia repair.",[221,222,27,223,224],"Laparoscopic Surgery","Herniorrhaphy","Transversus Abdominis Plane (TAP) Block","Postoperative Analgesia",[226,227,228,223],"Laparoscopic surgery","Inguinal hernia","postoperative analgesia","2025-09-19",{"date":231,"type":41},"2025-09-24",{"date":233,"type":41},"2025-09-04",{"date":235,"type":21},"2026-06-30",{"name":237,"class":48},"Başakşehir Çam & Sakura City Hospital",{"id":239,"slug":240,"hasResults":11,"nctId":241,"briefTitle":242,"officialTitle":243,"acronym":244,"eligibilityCriteria":245,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":246,"targetDuration":4,"studyType":22,"phases":248,"briefSummary":249,"conditions":250,"keywords":252,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":92},"100566107","desarda-tissue-technique-vs-lichtenstein-technique-for-primary-inguinal-hernia-repair-100566107","NCT06650878","Desarda Tissue Technique vs Lichtenstein Technique for Primary Inguinal Hernia Repair","Randomized Controlled Trial Comparing the Desarda Tissue Technique With the Lichtenstein Technique in Primary Inguinal Hernia Repair","HP-tis","Inclusion Criteria:\n\n* Diagnosed with primary inguinal hernia.\n* Body mass index below 31\n* Indication for inguinal hernia repair via anterior approach, either as outpatient surgery (CMA) or elective admission.\n* Legal capacity to provide informed consent.\n\nExclusion Criteria:\n\n* Patients with a weak, thin, or divided external oblique aponeurosis.\n* Participants diagnosed with any of the following conditions:\n\n  * Ongoing oncological disease\n  * Cirrhotic patients classified as Child B or higher\n* Women who have previously undergone a cesarean section\n* Cognitive or affective conditions that limit the ability to cooperate with the study procedures",{"count":247,"type":21},478,[24],"This study aims to evaluate whether a surgical technique (Desarda) is superior to the commonly used surgical technique (Lichtenstein) in inguinal hernia repair concerning the occurrence of postoperative complications. The Lichtenstein technique involves the use of a mesh, while the Desarda technique does not.",[27,251],"Complications of Surgical Procedures or Medical Care",[253,254,255],"Inguinal Hernia","lichtenstein technique","desarda technique","2025-06-18",{"date":258,"type":41},"2025-06-24",{"date":260,"type":41},"2025-03-26",{"date":262,"type":21},"2030-12-01",{"name":264,"class":91},"Consorci Sanitari de l'Alt Penedès i Garraf"]