[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inhibitory-control\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inhibitory-control":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,71,100,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100586503","bid-ltm-digital-intervention-in-aging-100586503",false,"NCT06916221","BID LTM Digital Intervention in Aging","Behavioral Intervention Development Core - Long Term Memory Digital Intervention in Aging","Inclusion Criteria:\n\n* Minimum of 12 years of education\n* English fluency: All task instructions are presented in English language text. In order to control for sufficient and equivalent participant comprehension of the procedures and instructions, we require their self-report of fluency in English.\n* Normal or corrected-to-normal vision\n* Normal or corrected-to-normal hearing\n* Medically healthy older adults, including those with below-average cognitive performance \u002FMCI patients without dementia referred by neuropsychologists (i.e., no participant medical records will be reviewed).\n\nExclusion Criteria:\n\n* Under the age of 60\n* Clinical diagnosis of neurological or psychiatric disorder Clinical diagnosis of dementia or AD8 score of \\>4\n* Visually or hearing impaired without correction to normal\n* Regularly (one or more times per week) practicing an instrument within the last year\n* 10 years or more of formal musical instrument training","ALL","60 Years","85 Years",{"count":20,"type":21},150,"ESTIMATED","INTERVENTIONAL",[24],"NA","Healthy aging is typically accompanied by diminished capability for learning and retrieval of high-fidelity long-term memory (LTM). The decline in these faculties is accelerated and becomes significant deficits in LTM and cognitive control functions at the level or a diagnosis of Mild Cognitive Impairment (MCI). Training with the navigation game, relative to training with control games, is expected to improve LTM performance for older adult participants.\n\nResearchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function.\n\nParticipants will conduct study activities remotely (e.g., at-home):\n\n1. Baseline Assessment. Complete a series of cognitive assessments and surveys.\n2. Intervention. Engage in a digital intervention for up to 8 weeks.\n3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment.\n4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.",[27,28,29],"Long-Term Memory","Inhibitory Control","Mild Cognitive Impairment",[31,32,33],"cognitive training","cognitive aging","memory","RECRUITING","2026-03-31",{"date":37,"type":38},"2026-04-02","ACTUAL",{"date":40,"type":38},"2025-08-20",{"date":42,"type":21},"2028-07-31",{"name":44,"class":45},"University of California, San Francisco","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":70,"locationsCount":46},"100586694","bid-wm-digital-intervention-in-aging-100586694","NCT06918704","BID WM Digital Intervention in Aging","Behavioral Intervention Development Core - Working Memory Digital Intervention in Aging","Inclusion Criteria:\n\n* Minimum of 12 years of education\n* English fluency\n* Normal or corrected-to-normal vision\n* Normal or corrected-to-normal vision\n* Medically healthy older adults including those with below-average cognitive performance or mild cognitive impairment patients without dementia\n\nExclusion Criteria:\n\n* Under the age of 60\n* Clinical diagnosis of neurological or psychiatric disorder\n* Visually or hearing impaired without correction to normal\n* Clinical diagnosis of dementia or AD8 score of \\>3\n* Regularly (one or more times per week) practicing an instrument within the last year\n* 10 or more years of formal musical instrument training",true,{"count":20,"type":21},[24],"The goal of this clinical trial is to learn if engaging with an digital intervention may improve cognitive function. The main questions it aims to answer are:\n\n1. Does engagement in with a digital intervention improve working memory?\n2. Does engagement in with a digital intervention improve inhibitory control?\n\nResearchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function.\n\nParticipants will conduct study activities remotely (e.g., at-home):\n\n1. Baseline Assessment. Complete a series of cognitive assessments and surveys.\n2. Intervention. Engage in a digital intervention for up to 8 weeks.\n3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment.\n4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.",[59,28,60,61],"Working Memory","Mild Cognitive Impairment (MCI)","Aging",[63,59,64,28,29,61],"Cognitive Training","MCI",{"date":66,"type":38},"2026-04-01",{"date":68,"type":38},"2025-08-15",{"date":42,"type":21},{"name":44,"class":45},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":79,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":46},"100536352","differences-between-suicide-attempters-and-suicide-ideators-influence-of-the-brief-therapy-attempted-suicide-short-intervention-program-assip-on-neuropsychological-correlates-and-psychological-process-factors---project-2-100536352","NCT06263712","Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2","Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy ASSIP on Neuropsychological Correlates and Psychological Process Factors (NePsyASSIP HT) - Project 2","NePsyAssip HT","Inclusion Criteria for Project 2:\n\nSubjects fulfilling the following inclusion criteria are eligible for the study:\n\n* Informed consent as documented by signature\n* Age ≥ 18 years\n* At least one previous suicide attempt\n* Willingness to attend the ASSIP brief therapy\n* Owns a smartphone\n\nExclusion Criteria for Project 2:\n\nThe presence of any one of the following exclusion criteria will lead to exclusion of the subject:\n\n* Serious cognitive impairment\n* Any psychotic disorder\n* Any current medication, which substantially impairs the attention span, reaction, rate or any other relevant cognitive functions\n* Inability to follow the procedures of the study (e.g., insufficient mastery of the German language, previous enrolment into the current study)","18 Years",{"count":81,"type":21},156,[24],"The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.\n\nThe overall aim of project 2 is to investigate how the (neuro-) psychological patterns are modulated by the Attempted Suicide Short Intervention Program (ASSIP). Therefore, suicide attempters participating in this project 2 will be randomly assigned to either the intervention group ASSIP or a standard care plus resource interview (STAR) group. The ASSIP and STAR interventions take place at the University Hospital of Psychiatry and Psychotherapy Bern (Switzerland).\n\nAt the end of the assessment in project 1 participants who reported a history of past suicide attempt (SUAT) will be informed about project 2.\n\nOnly if participants agreed to take part in project 2 and have signed the informed consent, they are randomized into two conditions: The ASSIP intervention (ASSIP) versus standard of care plus resource interview (STAR). Participants of both groups will be assessed again 4 weeks and 12 months after their first baseline assessment of project 1.",[28,85,86,87,88,89,90],"Self Efficacy","Suicide Ideation","Suicide, Attempted","Locus of Control","Process Factors","Movement Synchrony","2026-01-19",{"date":93,"type":38},"2026-01-22",{"date":95,"type":38},"2024-03-25",{"date":97,"type":21},"2026-12",{"name":99,"class":45},"University of Bern",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":77,"eligibilityCriteria":106,"healthyVolunteers":54,"sex":16,"minAge":79,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":109,"phases":4,"briefSummary":110,"conditions":111,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":46},"100535164","neuropsychological-patterns-of-suicide-ideators-and-suicide-attempters-100535164","NCT06248268","Neuropsychological Patterns of Suicide Ideators and Suicide Attempters","Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy ASSIP on Neuropsychological Correlates and Psychological Process Factors (NePsyASSIP HT) - Project 1","Inclusion Criteria:\n\nSubjects fulfilling the following inclusion criteria are eligible for the study:\n\n* Informed consent as documented by signature\n* Age ≥ 18 years\n\nAdditional inclusion criterion for the SUAT group in project 1:\n\n• At least one previous suicide attempt\n\nAdditional inclusion criterion for the SUID group in project 1:\n\n• Suicidal ideation\n\nAdditional inclusion criterion for the CLIN group in project 1:\n\n• Current psychiatric disorder treated on an inpatient, day-care or outpatient basis For the HLTH group, no further inclusion criteria are formulated.\n\nExclusion Criteria:\n\nThe presence of any one of the following exclusion criteria leads to exclusion of the subject:\n\n* Serious cognitive impairment\n* Any current psychotic disorder\n* Any current medication, which substantially impairs the attention span, reaction rate or any other relevant cognitive functions\n* Inability to follow the procedures of the study (e.g., insufficient mastery of the German language, previous enrolment into the current study)\n\nAdditional exclusion criterion for the SUID group:\n\n• Previous suicidal behavior\n\nAdditional exclusion criteria for the CLIN and HLTH groups:\n\n* Previous suicidal behavior\n* Suicidal ideation\n\nAdditional exclusion criterion for the HLTH group:\n\n• Current psychiatric disorder treated on an inpatient, day-care or outpatient basis",{"count":108,"type":21},180,"OBSERVATIONAL","The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.\n\nThe overall aim of project 1 is to determine (neuro-) psychological differences between suicide attempters, suicide ideators, a clinical control group, and healthy controls. Study participants in project 1 will participate in a one-time (neuro-) psychological assessment.\n\nProject 1 of this study is an observational cross-sectional study with four groups that will be conducted at the University Hospital of Psychiatry and Psychotherapy Bern (Switzerland): Patients with at least one suicide attempt in their past (SUAT), patients with suicidal ideation (SUID), patients from the same clinical cohort, without neither suicidal behavior or ideation (CLIN) and the healthy group (HLTH). The cohorts to be examined (SUAT \\& SUID) will be compared to the two control groups (CLIN \\& HLTH). Only people who have signed the informed consent and meet the eligibility criteria can participate in this study.",[28,88,85,87,112,113],"Suicidal Ideation","Attention","2026-01-15",{"date":116,"type":38},"2026-01-16",{"date":118,"type":38},"2024-08-08",{"date":120,"type":21},"2026-12-31",{"name":99,"class":45},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":54,"sex":129,"minAge":130,"maxAge":17,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":133,"briefSummary":134,"conditions":135,"keywords":151,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":46},"100617476","evaluation-of-the-impact-of-a-nutritional-formulation-on-cognitive-performance-following-stress-exposure-100617476","NCT07319117","Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.","A Double-blind, Placebo-controlled, Randomised, Acute, Repeated Measures Cross-over Study to Evaluate the Impact of Skoshify 'Think Tank' Nutritional Formulation on Cognitive Performance Following Stress Exposure.","Inclusion Criteria:\n\n1. Willing and able to provide written informed consent (in English)\n2. Aged 40-60\n3. Female\n4. Daily caffeine drinkers\n5. Healthy and free from significant physical and psychiatric disorders\n\nExclusion Criteria:\n\n1. Current cigarette smokers\u002Fvapers.\n2. Known food allergy or intolerance to the investigational products or control products.\n3. Not willing to consume coffee.\n4. Individuals diagnosed with psychiatric\u002Fmental health conditions.\n5. Individuals engaging in recreational drug use.\n6. Individuals with diagnosed cardiovascular conditions (e.g. heart disease, high blood pressure)\n7. Individuals taking prescribed medication except contraceptives\u002Fhormone replacement therapy\n8. Individuals suffering from Raynaud's or circulatory issues\n9. Individuals who have suffered an injury or infection in their hand\u002Farm in the last month\n10. Individuals who have suffered from chronic pain conditions or experience extreme numbness or pain in response to cold temperatures.\n11. Previous brain injury\u002Fbrain surgery\n12. Individuals who work night shifts.\n13. Currently pregnant or breastfeeding.\n14. Previous participants in a laboratory stress protocol.","FEMALE","40 Years",{"count":132,"type":21},40,[24],"The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor. Adopting a double-blind repeated measures cross-over design, middle-aged females (40-60 years) will be recruited to take part in a two-stage research study that will examine whether the formulation enhances cognitive performance and subjective well-being following the challenge of a stressor, compared to placebo. Cognitive assessments will examine the impact of the nutritional formulation on working memory, sustained attention, cognitive flexibility and inhibitory control. The study will also assess physiological (heart rate, blood pressure and cortisol) and subjective (well-being, anxiety, positive and negative mood, stress) markers of stress reactivity. The study will also explore levels sleep quality, mental and physical fatigue, effort, productivity, and perceived impact of the intervention.",[136,59,137,138,28,139,140,141,142,143,144,145,146,147,148,149,150],"Cognitive Assessment","Executive Function (Cognition)","Sustained Attention","Cognitive Flexibility","Cortisol","Stress","Anxiety","Depression","Sleep Quality","Blood Pressure","Heart Rate","Mental Fatigue","Physical Fatigue","Productivity","Effort",[152,153,154,155,156,157,158,159,160],"Cognitive Performance","Stress Response","Creatine","Magnesium","L-Tyrosine","L-Theanine","Rhodiola","Phosphatidylserine","Citicoline","2025-12-19",{"date":163,"type":38},"2026-01-06",{"date":165,"type":21},"2025-12-15",{"date":167,"type":21},"2026-08-31",{"name":169,"class":45},"Leeds Beckett University"]