[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"injection-fear\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:injection-fear":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100624171","nonpharmacological-management-of-pain-and-fear-during-hormone-injection-in-breast-cancer-patients-100624171",false,"NCT07406165","Nonpharmacological Management of Pain and Fear During Hormone Injection in Breast Cancer Patients","ShotBlocker and Helfer Technique in the Management of Pain and Fear During Hormone Injection in Patients With Breast Cancer: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years.\n* Patients diagnosed with breast cancer.\n* Requirement of intramuscular (IM) injection of premenopausal or postmenopausal hormonal medications as part of their prescribed treatment.\n* Cognitive competence to provide informed consent for the injection procedure. Intact skin integrity and normal sensory perception at the injection site (gluteal region).\n\nExclusion Criteria:\n\n* History of chronic pain disorders, neuropathic pain syndrome, or any disease requiring regular analgesic use.\n* Presence of neurological or cognitive disorders that may alter pain or fear perception.\n* Use of analgesics within the last 24 hours (or a specific timeframe relevant to your study).","ALL","18 Years","65 Years",{"count":20,"type":21},99,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled study will compare the effects of the ShotBlocker device and the Helfer Skin Tap Technique on pain and fear during intramuscular hormone injections in premenopausal and postmenopausal breast cancer patients. Ninety-nine participants will be randomly assigned to three groups (ShotBlocker, Helfer, control). All injections will be administered by the same nurse using standardized procedures. Pain will be assessed with the Visual Analog Scale, and fear with the Injection Fear Scale. The study aims to identify effective nonpharmacological methods to enhance patient comfort, support treatment adherence, and improve nursing care quality.",[27,28,29,30,31],"Breast Cancer","Pain Management","Fear","Injection Fear","Injection Pain Prevention",[33,34,35,36,37],"Breast cancer","Hormone therapy","Intramuscular injection","Pain","Injection fear","NOT_YET_RECRUITING","2026-02-11",{"date":41,"type":42},"2026-02-13","ACTUAL",{"date":44,"type":21},"2026-02-10",{"date":46,"type":21},"2026-07",{"name":48,"class":49},"Inonu University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":50},"100566177","does-ethyl-chloride-spray-work-100566177","NCT06651788","Does Ethyl Chloride Spray Work?","Does \"Freeze Spray\" Work? Evaluating the Efficacy of Ethyl Chloride Usage Prior to Orthopaedic Injections","Inclusion Criteria:\n\n* 18 years and older\n* Receiving a corticosteroid injection in an upper or lower extremity (to include soft tissue and joint injections) for the first time\n\nExclusion Criteria:\n\n* Patients with previous injection experiences",{"count":59,"type":21},300,[24],"A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.",[30,31,63],"Injection Complication",[65,66,67,68,69],"Injection","Freeze spray","corticosteroid injections","Ethyl chloride","Orthopeadics","RECRUITING","2025-10-14",{"date":73,"type":42},"2025-10-16",{"date":75,"type":42},"2025-04-01",{"date":77,"type":21},"2028-12-01",{"name":79,"class":49},"University of Chicago",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":4},"100602574","exposure-based-cbt-for-youth-with-blood-and-injection-phobia-and-chronic-illness-100602574","NCT07125287","Exposure-Based CBT for Youth With Blood and Injection Phobia and Chronic Illness","\"Confront the Fear\" - Evaluation of a Novel Exposure-Based CBT for Youth With Blood and Injection Phobia and Concurrent Somatic Illness Requiring Injections","Inclusion Criteria:\n\n1. Age 12-17 years;\n2. Blood-Injection-Injury (BII) phobia;\n3. Somatic disease or condition requiring regular injections and\u002For blood sampling;\n4. Ability to read and write in Swedish.\n\nExclusion Criteria:\n\n1. Significant cognitive or intellectual impairment;\n2. Severe psychopathology (e.g., suicidality);\n3. Acute trauma;\n4. Ongoing or recently completed treatment for BII phobia.","12 Years","17 Years",{"count":90,"type":21},30,[24],"More than half of all children fear needles, and hospitalized children often describe injections as the most frightening part of medical care. While mild needle fear can often be managed by healthcare staff using distraction and reassurance, these strategies are ineffective for children with blood-injection-injury phobia (BII phobia). Children with BII phobia and co-occurring chronic medical conditions often require repeated blood tests or injections, but their phobia may prevent essential treatment. In such cases, healthcare providers may be forced to use physical restraint, sedation, or general anesthesia-approaches that are distressing for the child and costly for the healthcare system.\n\nAlthough exposure-based cognitive behavioral therapy (CBT) is an effective treatment for specific phobias in adults, there is very limited research on CBT for children with BII phobia, particularly those with serious medical conditions. At the Department of Behavioral Medicine at Karolinska University Hospital, we have developed an exposure-based CBT intervention tailored for children with BII phobia and co-occurring somatic illness. The program includes a home-based training kit with medical materials to support frequent and realistic exposure between clinic sessions. Clinical experience suggests the intervention improves fear responses and increases medical treatment adherence, but it has not yet been formally evaluated.\n\nThis study aims to evaluate the feasibility and effectiveness of this novel CBT intervention for children and adolescents with disabling BII phobia and chronic somatic conditions.",[94,30],"Blood Injury Phobia",[96,97,98],"Phobia exposure","CBT","Needle exposure practice kit for home use","2025-08-12",{"date":101,"type":42},"2025-08-15",{"date":103,"type":21},"2025-09-01",{"date":105,"type":21},"2027-12-31",{"name":107,"class":108},"Region Stockholm","OTHER_GOV"]