[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"injection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:injection":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100625083","effects-of-cold-spray-and-buzzy-device-an-pain-and-fear-during-penicillin-injection-100625083",false,"NCT07418021","Effects of Cold Spray and Buzzy Device an Pain and Fear During Penicillin Injection","The Effect of Innovative Cold Applications (Cold Spray and Buzzy Device) on Pain and Fear Associated With Penicillin Injection: A Randomized Controlled Trial","Eligibility Criteria\n\nInclusion Criteria:\n\nAdults aged 18 years and older\n\nIndividuals scheduled to receive intramuscular penicillin injection\n\nAble to communicate and report pain and fear levels\n\nWilling to participate in the study\n\nProvided written informed consent\n\nExclusion Criteria:\n\nKnown allergy or hypersensitivity to cold applications\n\nSkin lesions, infection, or injury at the injection site\n\nNeurological or psychiatric conditions that may affect pain or fear perception\n\nUse of analgesic or anxiolytic medication prior to injection\n\nPrevious adverse reaction to intramuscular injections",true,"ALL","18 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study investigates the effect of cold spray and Buzzy devices on pain and fear experienced during penicillin injections. There are three groups: a cold spray and Buzzy device, and a control group. Penicillin injections are commonly used in clinical practice and can cause discomfort, pain, and fear, particularly in patients receiving intramuscular injections.\n\nCold spray and Buzzy devices are non-pharmacological methods that can help reduce pain and fear by providing a cooling effect and vibration at the injection site. Participants will be randomly assigned to one of the study groups, and their pain and fear levels during injection will be assessed using standardized measurement tools.\n\nThe results of this study are expected to contribute to improving patient comfort and supporting the use of simple, non-invasive methods to reduce pain and fear during injections.",[27,28,29],"Injection","Pain Management","Fear",[31,27,32],"Pain","Injection fear","NOT_YET_RECRUITING","2026-02-10",{"date":36,"type":37},"2026-02-18","ACTUAL",{"date":39,"type":21},"2026-02-05",{"date":41,"type":21},"2026-05-05",{"name":43,"class":44},"Inonu University","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":61,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100457884","a-study-of-huperzine-a-injection-in-reducing-postoperative-delirium-in-elderly-patients-undergoing-non-cardiac-surgery-100457884","NCT05242419","A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery","A Multi-center, Randomized, Double-blinded, Placebo-controlled Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery","Inclusion Criteria:\n\n* ≥ 75 years old.\n* Comply with the indication of non-cardiac surgery under general anesthesia.\n* Anesthesia grade of American Society of Anesthesiologist (ASA) as III\\~IV grade.\n* The estimated operation time ≥ 2 hours.\n* Voluntarily sign the informed consent form.\n\nExclusion Criteria:\n\n* Patients with impaired renal function (Cr is 1.5 times higher than the upper limit of the normal value of the central laboratory) or abnormal liver function (Alanine aminotransferase(ALT) and Aspartate aminotransferase(AST) are 2 times higher than the upper limit of the normal value of the central laboratory).\n* Patients who are positive for infectious diseases.\n* Patients accompanied with central nervous system injury.\n* Patients with previous history of delirium and epilepsy, long-term use of psychoactive drugs or preoperative assessment of delirium.\n* Patients who involved diseases with drug taboos, bronchial asthma, mechanical intestinal obstruction and urinary tract obstruction, or serious systemic diseases, especially circulatory diseases: such as myocardial infarction, heart failure, angina pectoris, history of sinus bradycardia.\n* Patients who are known to be allergic to narcotic drugs or Huperzine A Injection, or must use drugs that are not compatible with Huperzine An Injection.\n* patients who participated in other clinical trials within 3 months before this study, for any reason, who could not tolerate the test or cooperate with the examination, or who has any aphasia, audio-visual dysfunction, etc.\n* the investigators think that the patients is not suitable to participate in this study.","75 Years",{"count":54,"type":21},40,[24],"To observe and study the clinical effect of Huperzine A Injection on reducing postoperative delirium in elderly patients undergoing non-cardiac surgery",[27,58,59,60],"Non-cardiac Surgery","Delirium in Old Age","Post Operative Delirium",[62,63,58,64],"Huperzine A Injection","postoperative delirium","Elderly Patients","RECRUITING","2025-03-27",{"date":68,"type":37},"2025-04-02",{"date":70,"type":37},"2022-06-10",{"date":72,"type":21},"2025-12-30",{"name":74,"class":44},"Second Affiliated Hospital of Wenzhou Medical University",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":52,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":75},"100576842","music-effect-on-the-self-injection-testing-fear-and-pain-100576842","NCT06790550","Music Effect on the Self-Injection, Testing Fear and Pain","Examination of Music's Demonstration to Self-Injection, Fear of Testing and Pain in Patients With Type 2 Diabetes","Inclusion Criteria:\n\n* Type 2 diabetes for at least one year\n* Self-administering insulin injection\n* Self-administering glucometer, insulin pen or insulin pump\n\nExclusion Criteria:\n\n* poor mental health\n* Having gestational diabetes mellitus or Type 1 diabetes\n* no hearing problems","15 Years",{"count":85,"type":21},100,[24],"Diabetes is a chronic and broad-spectrum metabolic disorder characterized by hyperglycemia that occurs due to relative or absolute insulin deficiency or \"insulin resistance\" developed against insulin action in peripheral tissues, affecting many organs and causing multisystem involvement. Metabolic function continues to deteriorate after diagnosis, leading to worsening glycemic control and insulin therapy becoming necessary. However, patients may have difficulty adhering to insulin therapy. Fears about injections are common in both adults and children and, as research shows, are a major reason why people with diabetes avoid taking insulin. Addressing these fears is an important part of helping patients reduce their risk of diabetes-related complications. Helping patients manage their replacement pain may help reduce the effects of needle fear in the future. There are a number of strategies that can ease the pain.The use of music in pain management has advantages such as being reliable, cheap, and having no side effects, as well as reducing postoperative pain reports. Music distracts the individual from negative stimuli and allows them to focus on something they enjoy, thus reducing pain and anxiety. Music therapy has also been shown to have sedative-protective effects and reduce stress hormone levels. Listening to preferred music can distract and reduce the pain and negative emotions associated with an unpleasant experience.",[89,90,29,31,27,91],"Type 2 Diabetes Mellitus (T2DM)","Insulin","Music Therapy",[93,90,94,95,96,97],"type 2 diabetes mellitus","fear","pain","insulin injection","music","2025-01-24",{"date":100,"type":37},"2025-01-28",{"date":102,"type":21},"2025-01-30",{"date":104,"type":21},"2025-07-30",{"name":106,"class":44},"Dicle University"]