[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"injury-traumatic\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:injury-traumatic":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,50,79,110,151,178],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100563640","recovery-legal-care-clinical-trial-100563640",false,"NCT06618794","Recovery Legal Care Clinical Trial","HVIP-MLP","Inclusion Criteria:\n\n* Treatment for an interpersonal violent injury at the University of Chicago Trauma Center (e.g., gunshot, stab wound, assault)\n* Ages 14+ years\n* Able to provide informed consent (18 years and older) or assent (14-17 years)\n\nInclusion of women and minorities: This research proposal includes women and ethnic minorities. Patient participants will be primarily non-Hispanic Black or Hispanic race and ethnicity. The study expects participants to be proportional to the population-wide estimates for the South Side community. The majority will be low-income with variable functional health literacy. These characteristics are representative of the target population and describe the population most likely to benefit from the proposed study. Youth stakeholder participants will be multi-ethnic and racially diverse.\n\nInclusion of children: This study will include children ages 14-17 years old, based on Illinois state labor laws for child employment, as well as the ages of youth who are primarily treated for penetrating injury at the UCMC trauma center. This age is also a pragmatic cutoff for children providing meaningful input on community and healthcare solutions to violence.\n\nExclusion Criteria:\n\n* Diagnosis of severe mental illness (e.g., psychotic disorder, schizophrenia, suicidality)\n* Treated for a non-interpersonal violent injury type (e.g., car accident)\n* Treated for self-inflicted or accidental injuries\n* Unable to provide informed consent due to mental status\n* Prior receipt of legal services at UCMC within the past year\n* Currently imprisoned or incarcerated\n* Residing at a non-Illinois address\n* Non-English speakers","ALL","14 Years",{"count":19,"type":20},500,"ESTIMATED","INTERVENTIONAL",[23],"NA","Hospital-Based Violence Intervention Programs (HVIPs) affiliated with trauma centers in the US often focus on individual behavior modification for reduction in re-victimization. There is a lack of reproducible evidence that has demonstrated effectiveness, given the exclusion of addressing inequities in the Social and Structural Determinants of Health (SSDOH), often the root causes of violent injury and preventable homicide. The study investigators created a Medical Legal Partnership (MLP) to partner with an existing HVIP. This novel program offers beside legal assistance to address the SSDOH. The purpose of this study is to evaluate the effectiveness of the HVIP-MLP program in improving perceived stress, violence-related outcomes, legal needs, health-related quality of life, and PTSD symptoms.",[26,27,28],"Firearm Injury","Economic Problems","Injury Traumatic",[30,31,32,33,34,35,36],"Firearm injury","Community violence","Medical-Legal Partnership","Structural violence","Civil law attorneys","Health-Harming Legal Needs","Hospital-Based Violence Intervention Program","RECRUITING","2026-06-04",{"date":40,"type":41},"2026-06-08","ACTUAL",{"date":43,"type":41},"2025-02-10",{"date":45,"type":20},"2027-08-31",{"name":47,"class":48},"University of Chicago","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100538530","human-centered-injury-thrivorship-pathway-for-survivors-of-physical-trauma-100538530","NCT06292039","Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma","Identifying & Addressing Unmet Needs of Injury Survivors at a Safety Net Hospital in San Francisco","Inclusion Criteria:\n\n* Patient ≥ 18 years old presenting with a physical injury to Zuckerberg San Francisco General Hospital\n* Admitted to the hospital ≥ 24 hours\n* Discharged from the hospital alive\n* San Francisco resident or unhoused in San Francisco\n* Capacity for informed consent\n\nExclusion Criteria:\n\n* Patient \\\u003C 18 years old\n* Deceased during index hospitalization\n* Unable to provide informed consent","18 Years",{"count":59,"type":20},25,[23],"The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors. The main question it aims to answer is:\n\n• Is the pathway appropriate, acceptable, and feasible to meet the medical and social needs of injury survivors?\n\nInjury survivors will be purposively sampled to enroll in the pathway and asked to participate in in-depth interviews and their use of pathway resources will be tracked.",[28,63,64],"Survivorship","Trauma Injury",[66,67,68],"Social determinants of health","Community-engaged research","Unmet needs","NOT_YET_RECRUITING","2026-04-29",{"date":72,"type":41},"2026-05-01",{"date":74,"type":20},"2027-01",{"date":76,"type":20},"2027-06",{"name":78,"class":48},"University of California, San Francisco",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":16,"minAge":57,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":49},"100574856","cryopreserved-hair-follicles-for-disease-and-cell-replacement-100574856","NCT06764719","Cryopreserved Hair Follicles for Disease and Cell Replacement","Characterization of Cryopreserved Plucked Hair Follicles and Generation of Functional Cell Lines for Disease Modeling and Cell Replacement Therapies","Inclusion Criteria:\n\n* Gender: Male or Female.\n* Age: ≥18 and ≤80 years.\n* Language proficiency: Able to read and understand English.\n* Informed consent: Willing to provide written, informed consent to participate in all study activities.\n\nExclusion Criteria:\n\n* Scalp\u002FHair Disorders: Subjects diagnosed with active scalp infections or inflammatory skin conditions.\n* Systemic Conditions: Subjects with chronic illnesses, such as autoimmune diseases or diabetes, that may impact scalp health or wound healing.\n* Medications: Subjects on immunosuppressants, steroids, or other medications associated with hair loss.",true,"80 Years",{"count":89,"type":20},100,"OBSERVATIONAL","To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.",[93,94,28],"Diabetes Mellitus","Sport Injury",[96,97,98,99],"Hair follicles","stem cells","pluripotent","cell differentiation","2025-09-29",{"date":102,"type":41},"2025-10-02",{"date":104,"type":41},"2025-01-06",{"date":106,"type":20},"2026-03",{"name":108,"class":109},"Acorn Biolabs Inc.","INDUSTRY",{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":86,"sex":16,"minAge":118,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":21,"phases":122,"briefSummary":123,"conditions":124,"keywords":134,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":49},"100542080","advice-of-moderate-drinking-pattern-versus-advice-on-abstention-on-major-disease-and-mortality-100542080","NCT06338215","Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality","A Non-inferiority Randomized Trial Testing an Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality","UNATI","Inclusion Criteria:\n\n* Males aged 50-70 years, Women aged 55-75 years\n* Drinkers of any alcoholic beverage initially consuming 3 or more but 40 or less drinks\u002Fwk\n* Projected life expectancy more than 5 years (according to the judgment of their attending physician)\n* Willing to receive advice during up to 4 years on how to improve their alcohol intake making it healthier\n\nExclusion Criteria:\n\n1. Participants without smartphone or a computer (or tablet) with Internet connection.\n2. Drinkers of less than 30 g of pure alcohol\u002Fwk or more than 400 g of pure alcohol\u002Fwk\n3. Illiteracy, inability\u002Funwillingness to give written consent or communicate with study staff, or inadequate abilities for the use of on-line technologies\n4. Participants with any sever psychiatric condition or with a diagnosis of cognitive impairment or dementia.\n5. Participants with liver cirrhosis or prior liver cancer.\n6. Patients with a recent diagnosis of breast cancer (diagnosed in the last 10 years).\n7. Patients under habitual use of high-dose medications that completely preclude any use of alcohol. Most of these patients will be already excluded by the second or fourth exclusion criteria.","50 Years","75 Years",{"count":121,"type":20},10000,[23],"The goal of this clinical trial is to test two advices on alcohol drinking in more than 10.000 Spanish adult drinkers (men of 50 or more years and women of 55 or more years).\n\nThe main question it aims to answer is to test the non-inferiority advice of a moderate alcohol drinking pattern on all-cause mortality and other chronic disease like cardiovascular disease, cancer or type 2 diabetes.\n\nParticipants will receive during 4 years an advice to drink alcohol following a Mediterranean Alcohol Drinking Pattern (MADP): consuming alcohol in moderation, avoidance of binge drinking and preference for red wine.\n\nResearchers will compare those who will receive a MADP advice with those who will receive an advice on abstention to see if the advice on MADP is not inferior than the abstention advice to prevent all-cause mortality and other chronic diseases.",[125,126,127,128,129,130,131,28,132,133],"All Cause Mortality","Cardiovascular Diseases","Invasive Cancer","Liver Cirrhosis","Type 2 Diabetes","Depression","Dementia","Tuberculosis","Infections",[135,136,137,138,139,140,141],"Alcohol","Drinking Pattern","Abstention","Advice","Clinical Trial","Moderation","Mediterranean Alcohol Drinking Pattern","2024-12-11",{"date":144,"type":41},"2024-12-12",{"date":146,"type":41},"2024-05-15",{"date":148,"type":20},"2029-06-30",{"name":150,"class":48},"Clinica Universidad de Navarra, Universidad de Navarra",{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":4,"eligibilityCriteria":157,"healthyVolunteers":11,"sex":16,"minAge":158,"maxAge":4,"enrollmentInfo":159,"targetDuration":4,"studyType":21,"phases":161,"briefSummary":162,"conditions":163,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":4},"100562467","the-effect-of-digital-education-for-osteoporosis-patients-on-fracture-risk-and-related-health-outcomes-100562467","NCT06603545","The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes.","The Effect of Digital Education for Osteoporosis Patients on Fracture Risk and Related Health Outcomes in Older Swedish Men and Women.","Inclusion Criteria:\n\n* Patients visiting an osteoporosis unit, 65 years and older.\n* Ability to understand and follow study instructions.\n* Signed informed consent.\n* Have been recommended pharmacological osteoporosis treatment after a clinical evaluation including a DXA-scan and assessment of fracture risk at an osteoporosis clinic.\n* Have access to www.1177.se.\n\nExclusion Criteria:\n\n* Patients with previous osteoporosis medication the last year.","65 Years",{"count":160,"type":20},2640,[23],"A digital education for osteoporosis patients (DEOP) has been developed and tested on patients in Region Vastra Gotaland, Sweden. Currently, the evidence regarding the efficacy of patient education on fracture risk, medication adherence, injurious falls, levels of physical activity, and diet is insufficient. Most patients with osteoporosis in Sweden are diagnosed and treated in primary care, where the knowledge about osteoporosis is often very limited. Thus, in general, osteoporosis patients are not sufficiently informed before receiving a treatment recommendation. This randomized controlled trial aims to investigate if DEOP vs. standard care can reduce the incidence of fracture in older women and men, and if the intervention leads to better adherence to osteoporosis medication, higher quality of life, increased physical activity, and enhanced diet.\n\nThe primary objective is to investigate if DEOP compared to standard care (without DEOP), can reduce the incidence of clinical fractures in men and women, over the age of 65 years, without previous osteoporosis medication the last year, who have been recommended osteoporosis treatment after a DXA scan and assessment of clinical risk factors at an osteoporosis clinic.\n\nThe secondary objectives are to investigate if DEOP compared to standard care (without DEOP), can reduce the incidence of injurious falls, have positive effects on adherence to osteoporosis medication, positively affect diet (calcium and vitamin D intake), physical activity, and improve quality of life in men and women, over the age of 65 years, without previous osteoporosis medication the last year, who have been recommended osteoporosis treatment after a DXA scan and assessment of clinical risk factors at an osteoporosis clinic.\n\nStudy design: randomized multicentre clinical trial. Patients over the age of 65 visiting an osteoporosis unit for a bone density scan (DXA) will be asked to participate in the study. The participants will be randomized to one of two arms where one arm will be invited to DEOP and the other arm will receive standard care, without DEOP.",[164,165,166,167,168,28],"Osteoporosis","Accidental Falls","Fractures, Bone","Patient Reported Outcome Measures","Drug Adherence","2024-09-16",{"date":171,"type":41},"2024-09-19",{"date":173,"type":20},"2024-09",{"date":175,"type":20},"2029-12",{"name":177,"class":48},"Sahlgrenska University Hospital",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":185,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":187,"conditions":188,"keywords":190,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":49},"100555621","safety-and-efficacy-of-sufentanil-administration-by-paramedics-in-acute-trauma-100555621","NCT06514469","Safety and Efficacy of Sufentanil Administration by Paramedics in Acute Trauma","Safety and Efficacy of Sufentanil Administration by Paramedics in Acute Trauma in Prehospital Setting: Observational Study","Inclusion Criteria:\n\n* acute trauma with severe pain (VAS\u002FNRS \\> 4)\n* age \\> 18 years\n* conscious patient (GCS = 15; alert in AVPU)\n* haemodynamically stable patient (\\> 100mmHg of systolic blood pressure, \\> 60\u002Fmin of heart rate)\n\nExclusion Criteria:\n\n* EMS doctor on site\n* paediatric patient (less than 18 years)\n* predominantly chronic but not acute pain\n* incomplete documentation\n* other than traumatic reasons for opioid administration (eg. acute coronary syndrome)",{"count":186,"type":20},300,"The safety and efficacy of competence of paramedics to administer sufentanil intravenously in adult acute trauma patients without presence or without phone-call consult with an emergency medical doctor will be assessed in this observational study.\n\nCondition or disease: pain in trauma or injury. Intervention\u002Ftreatment: sufentanil administered by paramedics after the phone call consultation of medical doctor versus sufentanil administered by paramedics based on their competency, without consultation of medical doctor.",[28,189],"Pain, Acute",[191,192,193,194,195,196],"sufentanil","acute trauma","pain","paramedic","competence","prehospital","2024-07-16",{"date":199,"type":41},"2024-07-23",{"date":201,"type":41},"2024-07-01",{"date":203,"type":20},"2025-03-31",{"name":205,"class":48},"Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O."]