[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"inpatients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:inpatients":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,48,89,115,146,170,204],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100630828","effect-of-using-a-reminder-to-encourage-patients-to-be-active-during-their-hospital-stay-100630828",false,"NCT07492745","Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay.","Effect of Using a Reminder to Encourage Patients to be Active During Their Hospital Stay : a Multicenter Randomised Controlled Double Blind Study.","REMOTIVE","Inclusion Criteria:\n\n* Patients aged 50 or over with a score of 4 or above on the Clinical Frailty Scale (vulnerable but not dependent patients, symptoms limiting activities, patients who are slower\u002Fmore fatigued).\n* Must be able to get up from a chair without assistance.\n* Patients must be able to communicate with staff, understand instructions, give consent, and cooperate with staff.\n\nExclusion Criteria:\n\n* Patients with an estimated hospital stay of less than 5 days.\n* Contraindications to physical activity determined by the medical team (e.g., cardiovascular instability, orthopedic contraindications, etc.).\n* Terminal illness.\n* Patients scheduled for surgery.\n* Pregnant women.\n* People who do not understand French.\n* People protected under the law.","ALL","50 Years",{"count":20,"type":21},204,"ESTIMATED","INTERVENTIONAL",[24],"NA","Around 30% of patients aged 65 and over experience functional decline due to hospitalization. Physical inactivity, often without medical justification, is common during hospital stays.This immobility leads to loss of autonomy, muscle strength, and increases post-discharge risks.\n\nSlow walking for 25-40 minutes daily significantly improves functional capacity. However, it could be difficult to reach this time of walking due to a lack of physiotherapist in hospital.\n\nA vibrating watch may encourage patients to walk or perform strengthening exercises. This simple intervention aims to improve function without requiring additional staff or resources",[27,28],"Inpatients","Frail",[30,31,32,33,34],"inpatients","physical activity","reminder device","frailty","functional independancy","RECRUITING","2026-06-15",{"date":38,"type":39},"2026-06-16","ACTUAL",{"date":41,"type":39},"2025-11-19",{"date":43,"type":21},"2029-01-01",{"name":45,"class":46},"Groupe Hospitalier du Havre","OTHER",4,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":70,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100640612","flumazenil-for-benzodiazepine-reversal-in-electroconvulsive-therapy-100640612","NCT07619092","Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy","Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy (FLEET): A Randomized Controlled Trial","FLEET","Inclusion criteria:\n\n* Current depressive episode (unipolar or bipolar), corresponding to ICD-10 codes F31.3-5, F32 or F33.\n* Admitted at a study affiliated department in the Mental Health Services of the Capital Region of Denmark\n* Referred to ECT by the regular psychiatrist and has given consent to ECT\n* Currently receiving treatment with a benzodiazepine and\u002For zopiclone, at a minimum daily dose equivalent to 0.5 mg lorazepam.\n\nExclusion criteria:\n\n* Involuntary treatment with ECT\n* Known gross abnormalities in brain structure deemed likely to influence cognitive functioning\n* Pregnancy or breast-feeding\n* Inability to read or understand Danish\n* Acute organic brain disease (e.g., delirium) influencing the ability to give informed consent\n* Any pre-existing condition associated with an increased risk of prolonged or uncontrollable seizures, including but not limited to epilepsy or alcohol- or benzodiazepine withdrawal states\n* Conditions associated with reduced metabolism of flumazenil (e.g., liver failure)","18 Years",{"count":58,"type":21},145,[24],"The goal of this study is to investigate whether administering flumazenil to reverse the effects of benzodiazepines and\u002For zopiclone during electroconvulsive therapy (ECT) can help reduce cognitive side effects without diminishing treatment effectiveness in hospitalized patients with depression.\n\nThe investigators hypothesize that blockade of the GABA receptor with flumazenil will reduce cognitive side effects through improved seizures and a reduced need for electrical charge escalation during the ECT series. Cognitive side effects will be measured by the total score on the Screening for Cognitive Impairment in Psychiatry (SCIP) (primary outcome) at follow-up after completion of the ECT series. Furthermore, it is expected that the flumazenil strategy will reduce pre-treatment anxiety and improve patient satisfaction (secondary outcomes). In addition, flumazenil strategy is hypothesized to have beneficial effects on subjective cognitive complaints, autobiographical memory, and executive functioning (secondary outcomes). Finally, the flumazenil strategy is expected to be associated with more favorable structural and functional changes in executive functioning and memory-related brain networks after completion of the ECT series, which may, in turn, be linked to better overall cognition and autobiographical memory (secondary outcome measures). For exploratory purposes, the study will also examine longitudinal changes in depressive symptoms and cognitive outcomes from baseline to follow-up (tertiary outcomes).\n\nInvestigators will compare two different pre-ECT benzodiazepine management strategies:\n\n1. Flumazenil strategy (experimental): continued benzodiazepine and\u002For zopiclone use up until the time of the ECT session, followed by administration of flumazenil immediately prior to ECT\n2. Benzodiazepine withholding strategy (treatment as usual):\n\ndiscontinuation of benzodiazepines and\u002For zopiclone prior to the ECT in accordance with standard clinical practice",[62,63,64,65,66,67,68,69,27],"Depression - Major Depressive Disorder","Bipolar Disorder (BD)","Functional Magnetic Resonance Imaging (fMRI)","Cognition","Autobiographical Memory","Electroconvulsive Therapy","ECT","Treatment Outcome",[71,72,73,74,75,76,27,77,78,69,65],"flumazenil","benzodiazepine reversal","electroconvulsive therapy","randomized controlled trial","functional magnetic resonance imaging","Autobiographical Memory Test (AMT)","Major Depressive Disorder","Bipolar Disorder","2026-05-27",{"date":81,"type":39},"2026-06-01",{"date":83,"type":39},"2026-01-15",{"date":85,"type":21},"2028-08",{"name":87,"class":46},"Anders Jørgensen",1,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":96,"targetDuration":4,"studyType":98,"phases":4,"briefSummary":99,"conditions":100,"keywords":102,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":114},"100559548","emus-enhanced-monitoring-using-sensors-after-surgery-100559548","NCT06565559","EMUs: Enhanced Monitoring Using Sensors After Surgery","EMUs","Participant Inclusion Criteria:\n\n* Adults 18 years and older.\n* Undergoing an elective or emergency major surgery procedure with a planned skin incision of 5 cm or greater. Any indication for surgery can exist, including benign, malignant, and trauma.\n* Willing and able to provide written informed consent.\n\nParticipant Exclusion Criteria:\n\n* Those under the age of 18.\n* A documented or suspected allergy to adhesive dressings.\n* Obstetric patients\n* Unwilling or unable to provide written informed consent.",{"count":97,"type":21},1332,"OBSERVATIONAL","Patients can become critically unwell following surgical operations. Delay in recognition of this deterioration can result in patient harm and even death. Wearable wireless sensors that record patients vital signs such as heart rate could help improve recognition of patient deterioration. The goal of this observational study: Enhanced Monitoring Using Sensors After Surgery (EMUs) is to determine if data from wearable physiological monitors can be used for the early detection of postoperative deterioration, while being acceptable to patients and healthcare staff. The study participants and surgical inpatients undergoing open surgery. There are 3 objectives which each represent a stage of the study:\n\n1. To perform usability testing of device with clinicians, nurses, and healthcare workers in non-clinical environment.\n2. To determine baseline postoperative monitoring practice across our network and perform device usability testing in clinical environment.\n3. To perform a shadow-mode cohort study with collection of time-stamped sensor clinical event data to determine relationships between physiological waveforms and patient deterioration.\n\nThis registration focuses on the shadow-mode cohort study.\n\nParticipants will wear wireless sensors on their chest and fingers, pre-, intra-, and post-operatively for up to 10 days. The sensors will record their vital signs such as heart rate, and oxygen levels. This will then be analysed, and used to aid the design of early detection algorithms that may be able to predict clinical illness or complications in this patient group. This is an observational study gathering real time data only. No changes in patient care will result, and in Stages 2 and 3 no sensor data will be available to clinical teams. This study will be performed in departments of general surgery in Benin, Ghana, Guatemala, India, Mexico, Nigeria, Rwanda, and the United Kingdom.",[101,27],"Surgery",[101,103,104],"Wearable Devices","Global Surgery","2026-02-06",{"date":107,"type":39},"2026-02-10",{"date":109,"type":39},"2024-02-28",{"date":111,"type":21},"2027-07-31",{"name":113,"class":46},"University of Edinburgh",17,{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":122,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":22,"phases":126,"briefSummary":127,"conditions":128,"keywords":130,"overallStatus":136,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":88},"100609932","impact-of-facility-dog-intervention-on-pediatric-patients-100609932","NCT07221006","Impact of Facility Dog Intervention on Pediatric Patients","Investigating the Impact of Facility Dog Intervention on Pediatric Patient Fear, Coping, and Anxiety During Inpatient Admission","Inclusion Criteria:\n\n* Children admitted to an inpatient unit at Children's Hospital Colorado Anschutz Medical Campus\n* Who are eight to 17 years old.\n\nExclusion Criteria:\n\n* Isolation precautions\n* Primary reason for admission is due to suicidality, self-injurious behavior, or injurious behavior\n* Patients with history of or currently presenting with aggression or unsafe behavior\n* Severe comorbidities secondary to traumatic brain injury, neurological disorder or neurodevelopmental issues that may confound study outcomes and administration of the study protocol (e.g., intellectual disability)\n* Not medically stable\n* Have a fear of dogs\n* Have an allergy to dogs\n* Have had a visit from a medical dog and medical dog handler during their current admission\n* Patient has an urgent or time-sensitive need requiring medical dog support - Patient is non-verbal.","8 Years","17 Years",{"count":125,"type":21},126,[24],"The goal of this clinical trial is to learn if medical dog intervention facilitated by a Certified Child Life Specialist (CCLS) impacts pediatric patient coping, fear, and anxiety during inpatient admissions. The main questions it aims to answer are:\n\nWhat impact does facility dog support via a CCLS have on patient fear, coping, and anxiety? What effect does facility dog support via a CCLS have on patient heart rate? Researchers will compare medical dog intervention facilitated by a CCLS, CCLS intervention, and a coloring activity to see if medical dog interventions positively impact coping, fear, and anxiety.\n\nParticipants will:\n\nReceive a visit from a medical dog and their CCLS handler, a CCLS, or a Child Life Activity coordinator.\n\nEngage in a mindfulness or coloring activity. Answer surveys regarding anxiety, coping, and fear. Have their heart rate measured before, during, and after their assigned intervention.",[27,129],"Pediatric",[131,132,133,134,135],"Emotional Support Dog","Pet Therapy Dog","Child Life Specialist","anxiety","fear","NOT_YET_RECRUITING","2025-10-31",{"date":139,"type":39},"2025-11-03",{"date":141,"type":21},"2025-12-01",{"date":143,"type":21},"2026-12-01",{"name":145,"class":46},"Children's Hospital Colorado",{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":154,"targetDuration":4,"studyType":22,"phases":156,"briefSummary":157,"conditions":158,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":47},"100591711","increasing-physical-activity-among-medical-inpatients-by-digital-nudging-of-patients-and-staff-100591711","NCT06983977","Increasing Physical Activity Among Medical Inpatients by Digital Nudging of Patients and Staff","Increasing Physical Activity Among Medical Inpatients by Digital Nudging of Patients and Staff - A Cluster Randomised Multicentre Study","IPAMINA","Inclusion Criteria:\n\n* Admitted to one of the participating wards\n* Has understood and signed informed consent\n* Reads and understands Danish, Faroese, Greenlandic or English\n\nExclusion Criteria:\n\n* Has an expected hospitalisation less than 24 hours after potential recruitment\n* Is not able to give informed consent to participate in the study\n* Has allergy towards band aid\n* Not able to (shortly) stand in an upright position even with maximal assistance\n* There are contraindications for the patient to mobilise or be physically active due to unstabilized acute medical conditions, including, but not limited to, acute aortic dissection, -myocardial infarction, -pulmonary embolism, -sepsis.\n* There are ethical concerns regarding the patients' participation in the study, including, but not limited to, the patient being:\n\n  * In the terminal phase of life\n  * In a crisis state regarding their disease\u002Fsituation and deemed unfit for participation\n\nTo ensure medically responsible inclusion of patients, the project personnel will consult and confer with the treatment responsible medical doctor, or their delegate, before including a potential participant for the trial.",{"count":155,"type":21},400,[24],"Sedentary behaviour among medical inpatients is strongly associated with hospital-associated functional decline and poses a severe threat to patients' functional capacity and independency. High human and socioeconomic costs underline the urgency to find solutions to this world-wide problem.\n\nObjective: This multicentre study, including a total of 400 patients from Copenhagen, Aalborg, Tórshavn, and Nuuk, will assess the effect of a digital intervention that aims to reduce sedentary behaviour and increase physical activity in medical inpatients.\n\nIntervention: Digital feedback and nudging regarding the patients' physical activity levels to patients and healthcare staff Design: Stepped-wedge cluster randomised multicentre trial Primary outcome: Daily average time of patients' physical activity (minutes).",[159,27,160],"Physical Activity","Digital Health","2025-05-21",{"date":163,"type":39},"2025-05-25",{"date":165,"type":39},"2025-05-19",{"date":167,"type":21},"2027-12",{"name":169,"class":46},"Bispebjerg Hospital",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":17,"minAge":178,"maxAge":179,"enrollmentInfo":180,"targetDuration":4,"studyType":22,"phases":182,"briefSummary":183,"conditions":184,"keywords":187,"overallStatus":136,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":202,"locationsCount":88},"100590212","a-trial-of-extended-reality-activities-to-enhance-leisure-participation-among-inpatients-with-persistent-mental-health-conditions-100590212","NCT06964477","A Trial of Extended Reality Activities to Enhance Leisure Participation Among Inpatients With Persistent Mental Health Conditions","A Randomized Controlled Trial of an Extended Reality-Based Occupational Therapy Intervention to Improve Leisure Participation in Inpatients With Persistent Mental Health Conditions","XR-MHLP","Inclusion Criteria:\n\n* Adults aged 20 to 65 years\n* Diagnosed with chronic schizophrenia or schizoaffective disorder (ICD-10 F20.x or F25.x)\n* Hospitalized continuously for at least 6 months\n* Clinically stable with no acute psychiatric symptoms\n* Able to walk independently and communicate verbally\n* Mini-Mental State Examination (MMSE) score ≥ 24\n\nExclusion Criteria:\n\n* History of epilepsy, severe motion sickness, or other seizure-related conditions\n* Significant visual or auditory impairments that may interfere with XR experience\n* Physical conditions that limit participation in leisure activities\n* Current diagnosis of substance abuse or major organic brain disorder\n* Inability to distinguish between reality and virtual environments","20 Years","65 Years",{"count":181,"type":21},25,[24],"The goal of this clinical trial is to evaluate the effects of an extended reality (XR)-enhanced occupational therapy leisure intervention on motivation, emotional engagement, and therapeutic participation among inpatients with chronic psychiatric conditions. The main questions it aims to answer are:\n\nCan the XR intervention improve leisure motivation, leisure-related attitudes, and emotional coping strategies in long-term hospitalized individuals with mental illness?\n\nDoes the XR intervention promote improvements in psychological health, volition, and occupational performance?\n\nResearchers will compare an XR-based leisure therapy group to a usual care group engaged in standard hospital leisure activities such as art, music, or reading. Participants will take part in weekly 40-minute sessions for 6 weeks. The XR group will use a custom-designed mobile VR program featuring immersive 360° leisure scenarios aligned with participants' interests and functional goals. Data collection includes standardized assessments (e.g., Interest Checklist, Volitional Questionnaire, COPM, PANSS) and semi-structured interviews to explore changes in motivation, coping, and perceived benefits.",[185,186,27],"Schizophrenia and Related Disorders","Mental Disorders",[188,189,190,191,192,193,194,195],"Leisure Activities","Virtual Reality Exposure Therapy","Augmented reality","Extend reality","Schizoaffective Disorder","Volition","Motivation","Emotional Regulation","2025-05-01",{"date":198,"type":39},"2025-05-09",{"date":200,"type":21},"2025-07-01",{"date":137,"type":21},{"name":203,"class":46},"Chia-Hui Hung",{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":211,"targetDuration":4,"studyType":98,"phases":4,"briefSummary":213,"conditions":214,"keywords":219,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":228,"locationsCount":47},"100578762","prevalence-of-post-anesthesia-care-unit-complications-and-associated-factors-100578762","NCT06815510","Prevalence of Post Anesthesia Care Unit Complications and Associated Factors","Multicentral Observational Prospective Study on Prevalence of Post Anesthesia Care Unit Complications and Associated Factors","Inclusion Criteria:\n\n* All patients admitted to the Post-Anesthesia Care Units (PACUs) following surgery under general, regional, or monitored anesthesia\n\nExclusion Criteria:\n\n* Patients who are taken directly to the ICU, ward, discharged, or transferred immediately after surgery.\n* Patients who do not provide informed consent for enrollment in the study.",{"count":212,"type":21},1532,"The post-anesthesia care unit (PACU) is a crucial component of the surgical process, providing patients with vital support and monitoring as they recover from anesthesia. Despite advancements in perioperative anesthesia, PACU complications are still common. PACU organization and setup in low-income country like Ethiopia is poor. Previous research's done in some neighbor African countries presumed to have comparable to sociodemographic and economical profile shows varied degree of incidence and prevalence of PACU complication and associated factors. The main objective of this study is to determine the prevalence of PACU complications and its associated factors.\n\nAn institutional based prospective cohort study will be conducted in the PACUs of the three selected tertiary care hospitals in Ethiopia from Februery 15, 2025 to June 30, 2025. These data will be compared with those obtained in a tertiary hospital in Spain.",[215,216,27,217,218],"Postoperative Care","Complications of Surgical Procedures or Medical Care","Ethiopia","Multicenter Prospective Study",[220,221],"postoperative complications","postanesthesia care unit","2025-02-26",{"date":224,"type":39},"2025-02-28",{"date":226,"type":39},"2025-02-24",{"date":200,"type":21},{"name":229,"class":46},"Ángel Becerra-Bolaños, MD PhD"]