[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intensive-care-neuropathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intensive-care-neuropathy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100343574","recovery-from-icuaw-following-severe-respiratory-and-cardiac-failure-100343574",false,"NCT03753412","Recovery From ICUAW Following Severe Respiratory and Cardiac Failure","Prospective Observational Study Regarding the Determinants of Functional Disability and Quality of Life in Patients Recovering From Severe Acute Cardiac or Respiratory Failure Considered for Mechanical Cardiorespiratory Support (CLEVERER)","CLEVERER","Inclusion Criteria:\n\n* Above the age of 18\n* Adults with severe cardio-respiratory failure requiring ECMO.\n* Adults who have had personal and professional consultees agree to enrol them in the trial.\n\nExclusion criteria:\n\n* Previous Stroke\n* Neuromuscular disease\n* Malignancy\n* Underlying neuromuscular disease\n* paediatrics","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.",[25,26,27,28,29,30,31],"Intensive Care Unit Syndrome","Intensive Care Neuropathy","Intensive Care (ICU) Myopathy","Acute Respiratory Distress Syndrome","Cardiac Failure","Respiratory Failure","Critical Illness Myopathy",[33,34,35,36,37],"Extra Corporeal Membrane Oxygenation (ECMO)","Intensive Care Unit Acquired Weakness (ICUAW)","Critical Illness Polyneuromyopathy (CIPM)","Ultrasound (US)","Health Related Quality of Life (HRQoL)","RECRUITING","2026-01-05",{"date":41,"type":42},"2026-01-07","ACTUAL",{"date":44,"type":42},"2019-04-09",{"date":46,"type":21},"2026-09-26",{"name":48,"class":49},"Barts & The London NHS Trust","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":61,"studyType":22,"phases":4,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":50},"100605792","predictive-validity-of-the-chelsea-critical-care-physical-assessment-tool-cpax-for-regaining-autonomy-three-months-after-icu-discharge-100605792","NCT07167121","Predictive Validity of the Chelsea Critical Care Physical Assessment Tool (CPAx) for Regaining Autonomy Three Months After ICU Discharge","Etude de validité Predictive du Chelsea Critical Care Physical Assessment Tool (CPAx) Quant au Retour de l'Autonomie à la Marche 3 Mois après la Sortie de réanimation","CPAx-Predict","Inclusion Criteria:\n\n* Patient affiliated with, or entitled to benefit from, a French social security system.\n* Patient who has received clear and comprehensive information about the study and has signed the informed consent form together with the investigator.\n* Age ≥ 18 years.\n* Having received at least 48 hours of invasive mechanical ventilation.\n* Previous hospitalization in the intensive care unit (ICU) at CHI Elbeuf-Louviers-Val-de-Reuil.\n* Prescription of physiotherapy during the ICU stay.\n* Eligible for the 3-month post-ICU follow-up in the day hospital based on at least one of the following criteria:\n\n  * Mechanical ventilation or catecholamine treatment (norepinephrine) for ≥ 5 days;\n  * Weight loss ≥ 5% during hospitalization (criterion for malnutrition);\n  * Significant muscle weakness (MRC score \\\u003C 28\u002F60);\n  * Presence of post-traumatic stress symptoms related to ICU stay (evaluated by the psychologist).\n* Ability to walk (with or without assistive devices) prior to ICU admission.\n\nExclusion Criteria:\n\n* Patient not affiliated with the French national health insurance system.\n* Documented pre-existing cognitive impairment likely to limit understanding of instructions and participation in functional assessments (e.g., dementia, intellectual disability, severe uncontrolled psychiatric disorder).\n* History of disabling chronic neuromuscular disease (e.g., amyotrophic lateral sclerosis, myopathy, progressive chronic polyneuropathy).\n* History of major pre-existing locomotor impairment preventing autonomous walking (e.g., paraplegia, uncompensated disabling arthropathy).\n* Refusal to participate in the study or withdrawal of consent at any time.\n* Person under legal guardianship, curatorship, or any other legal protection measure.\n* Simultaneous participation in another interventional study likely to interfere with the evaluation criteria of the present study.\n* Medical contraindication to performing the 6-minute walk test at 3 months (e.g., cardiovascular decompensation, acute pulmonary disease, persistent hemodynamic instability).",{"count":60,"type":21},25,"1 Year","This single-center observational study aims to explore the relationship between the CPAx score (Chelsea Critical Care Physical Assessment Tool), measured at ICU discharge, and the 6-minute walk test (6MWT) distance performed 3 months after discharge. The study targets patients who experienced prolonged mechanical ventilation and were admitted to the ICU at CHI Elbeuf-Louviers-Val-de-Reuil. Eligible participants must show signs of malnutrition, muscular weakness, or post-traumatic stress symptoms. Data collection includes the CPAx score, 6MWT distance, MRC score, and relevant clinical and demographic information. The primary objective is to determine whether the CPAx score can predict long-term functional recovery and guide post-ICU rehabilitation strategies. Participants will be evaluated during routine follow-up in the day hospital. This non-interventional study poses minimal risk to participants.",[64,26],"ICU Acquired Weakness",[66,67,64,68,69,70],"ICU","Physiotherapy","CPAx","Predictive Validity","Test","2025-09-25",{"date":73,"type":42},"2025-09-30",{"date":75,"type":42},"2025-09-01",{"date":77,"type":21},"2026-09-01",{"name":79,"class":80},"Centre Hospitalier Intercommunal Elbeuf-Louviers-Val de Reuil","OTHER_GOV"]