[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"internal-derangement-of-the-tempromandibular-joint\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:internal-derangement-of-the-tempromandibular-joint":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100598729","liquid-phase-concentrated-growth-factor-versus-conventional-arthrocentesis-in-temporomandibular-disc-displacement-100598729",false,"NCT07075276","Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement","Injection of Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Management of Temporomandibular Disc Displacement: A Randomized Controlled Clinical Trial","LPCGF in TMDs","Inclusion Criteria:\n\n* 1\\. Adults aged 18-45 years. 2. Patients scored as (ASA I).9 3. Presence of complete or nearly complete set of natural dentition with Angle class I occlusion. 4. Diagnosed with unilateral involvement of disc displacement, according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC\u002FTMD).10 5. Symptoms include one or more of the following: pain, joint sounds, and limited mandibular movement (Maximum Mouth Opening\\\u003C 40mm) 6. No prior surgical intervention for TMD. 7. Patient's willingness to participate and follow the study protocol.\n\nExclusion Criteria:\n\n* 1\\. TMJ pathology related to mechanical deformities 2. Psychiatric problems or presence of systemic diseases that may affect healing (e.g., uncontrolled diabetes, autoimmune disorders, hematologic or neurologic disorders, inflammatory or connective tissue disorders as well as rheumatological or previous infectious diseases, head and neck cancer). 3. Patient unwilling or has contraindication to MRI 4. Previous injections or surgical interventions of the TMJ. 5. Concurrent use of anticoagulants or anti-inflammatory medications within the last 30 days. 6. Pregnant or breastfeeding women. 7. History of trauma or infection in the TMJ region. 8. Allergy to local anesthetics or other components used in the study. 9. Patients diagnosed with (Disc Displacement with reduction with no pain or limited mandibular movements).",true,"ALL","18 Years","45 Years",{"count":22,"type":23},32,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to rigorously assess the effectiveness of LPCGF in the management of internal disc displacement in patients with TMD through a randomized clinical trial. By comparing LPCGF therapy with conventional arthrocentesis, this research looks to provide robust evidence on the efficacy, safety, and potential role of (LPCGF) as an alternative therapeutic choice for IDD.",[29,30,31],"Temporomandibular Disorders (TMD)","Internal Derangement of the Tempromandibular Joint","Anterior Disc Displacement",[33,34,35,36,37],"Temporomandibular disorder","Concentrated growth factor","Anterior disc displacement with reduction","Anterior disc displacement without reduction","Arthrocentesis","RECRUITING","2026-03-08",{"date":41,"type":42},"2026-03-11","ACTUAL",{"date":44,"type":42},"2025-10-01",{"date":46,"type":23},"2026-06-01",{"name":48,"class":49},"Horus University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":18,"minAge":58,"maxAge":20,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100566587","ultrasound-guided-versus-conventional-arthrocentesis-in-treatment-of-temporomandibular-joint-internal-derangement-100566587","NCT06657118","Ultrasound Guided Versus Conventional Arthrocentesis in Treatment of Temporomandibular Joint Internal Derangement.","Ultrasound Guided Versus Conventional Arthrocentesis in Treatment of Temporomandibular Joint Internal Derangement: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Adult patients aged 16 to 45 years of age having temporomandibular joint internal derangement.\n* Patients free from any systemic conditions and bone metabolic diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.\n* ASA 1-2 patients with no contraindications for GA\n* Patients who did not respond to conservative treatment.\n\nExclusion Criteria:\n\n* Patient with uncontrolled systemic diseases precluding administration of general anesthesia.\n* Handicaps and special needs patients.\n* Prisoners.","16 Years",{"count":60,"type":23},34,[26],"The use of Ultrasound as a guide in arthrocentesis of tempromandibular joint versus conventional anatomically guided arthrocentesis in treatment of temporomandibular joint internal derangement: A randomized clinical trial.",[30],"NOT_YET_RECRUITING","2025-08-02",{"date":67,"type":42},"2025-08-06",{"date":69,"type":23},"2025-10",{"date":71,"type":23},"2026-11",{"name":73,"class":49},"Samiha Abdelsalam Abdelaziz Abdelaziz"]