[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"internal-fixation-complications\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:internal-fixation-complications":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100556175","evaluation-of-fracture-migration-after-internal-fixation-of-femoral-neck-fractures-in-younger-adults-a-clinical-rct-using-rsa-100556175",false,"NCT06521671","Evaluation of Fracture Migration After Internal Fixation of Femoral Neck Fractures in Younger Adults: A Clinical RCT Using RSA","Evaluation of Femoral Neck Fracture Migration After Internal Fixation With an Angle Stable Implant Compared With Gold Standard Cannulated Cancellous Screws in Young Adults: Study Protocol for a Clinical RCT Using Radiostereometric Analysis","Inclusion Criteria:\n\n* Femoral neck fracture (DS720)\n* Age 18-64 years\n* Ability to speak and read Danish\n* Willingness to participate\n\nExclusion Criteria:\n\n* Pathological, basicervical or transcervical fracture\n* Clinical Frailty Scale ≥5, indicating mild to severe frailty prior to the fracture\n* Cognitive impairment that hinders informed consent\n* Previous fracture in the ipsilateral femur\n* Patients who are unwilling or incapable of following post-operative care instructions.\n* Comorbidities making the participant ineligible for internal fixation such as:\n\n  * Material sensitivity, documented or suspected\n  * Active or suspected latent infection, sepsis or marked local inflammation in or around the surgical area\n  * Compromised vascularity, inadequate skin or neurovascular status\n  * Compromised bone stock that cannot provide adequate support and\u002For fixation of the device due to disease, infection or prior implantation\n  * Other physical, mental, medical or surgical conditions that would preclude the potential benefit of surgery.","ALL","18 Years","65 Years",{"count":20,"type":21},75,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of the clinical trial is to compare different surgical methods for internal fixation of femoral neck fractures in younger adults.\n\nThe main question it aims to answer is:\n\nIs internal fixation with the novel implant consisting of three angle stable screws locked together by a plate equal to internal fixation with cancellous screws or a sliding hip screw in younger adults under 65 years of age in terms of fracture migration?\n\nThe study will examine how stable the fracture remains during healing. This will be measured by assessing how much the fracture moves after surgery using a highly precise imaging method called radiostereometric analysis (RSA). The study will also record complications and evaluate pain, health related quality of life, and hip function over time.\n\nThe participants will be treated with either a novel angle stable implant (Dynaloc), cannulated cancellous screws or sliding hip screw and followed up at 6 weeks, 12 weeks, 6 months and 12 months. Recruitment will continue until 75 participants, 25 in each group, have completed the 12-week follow-up for the primary outcome.",[27,28,29],"Femoral Neck Fractures","Internal Fixation; Complications","Hip Fractures",[31,32,33,34],"femoral neck fracture","radiostereometric analysis","hip fracture","internal fixation","RECRUITING","2026-01-24",{"date":38,"type":39},"2026-01-27","ACTUAL",{"date":41,"type":39},"2025-06-16",{"date":43,"type":21},"2028-12",{"name":45,"class":46},"Odense University Hospital","OTHER",4,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100527779","functional-outcome-after-orif-or-arthroplasty-for-femoral-neck-fracture-100527779","NCT06152198","Functional Outcome After ORIF or Arthroplasty for Femoral Neck Fracture","Internal Fixation Versus Hip Replacement in Older Adults with an Garden I\u002FII Femoral Neck Fracture: Physical Function and Pain in Elderly Patients - a Substudy of the Hipsther Trial","HipFunct","Inclusion Criteria:\n\n* Undisplaced (Garden I-II) femoral neck fracture (within 72h)\n* Treated at participating unit\n* Informed consent\n* Amenable for both treatment options\n* Included in the Hipsther trial\n\nExclusion Criteria:\n\n* No informed consent\n* Pathological or stress fracture\n* Peri-implant fracture\n* Previous inclusion of a contralateral Garden 1 or 2 femoral neck fracture","75 Years",{"count":58,"type":21},340,[24],"Aim To investigate the effect of internal fixation versus hip arthroplasty on physical function and pain in elderly patients.\n\nMethods This is a substudy of an on-going nationwide multicenter registry-based RCT named HipSTHeR- (Hip Screws or Total Hip replacement or undisplaced femoral neck fracture in elderly patients) \\[21\\]. The aim is to recruit 340 patients with undisplaced or minimally displaced femoral neck fracture, Garden 1 or 2, are randomized to surgery either with internal screw fixation or hip arthroplasty.\n\nThis substudy aims to investigate the potential differences between internal fixation versus hip arthroplasty regarding physical function and pain 4- and 12- months after surgery. Those included in the main study will be contacted by letter a few weeks after the surgery to be invited to participate in a further study. The assessor will then contact the person by telephone to answer further questions and to obtain informed consent. The follow-ups will be conducted over telephone and mail at 4 and 12 months. During the follow-up the participants will answer questions about their functional level.\n\nInformation on randomisation and fracture data will be acquired from the Swedish Fracture Register and treatment data from the Swedish Hip Arthroplasty Register.\n\nPrimary outcome The New Mobility Score will be used as the primary outcome with follow-up at 4- and 12 months.\n\nSecondary outcome WOMAC will be used as an additional hip specific patient reported outcome.\n\nActivities of daily living will be assessed with Katz ADL index to evaluate the patients' performance and the need of assistance in ADL.\n\nPatients' cognitive status will be assessed ALFI-MMSE, adapted from Adult Lifestyles and Function Interview (ALFI-MMSE).\n\nThe Geriatric Depression Scale (GDS-15), which are developed to identify depressive symptoms.\n\nThe Philadelphia Geriatric Center Morale Scale (PGCMS) and have been used in several studies including frail people living in residential care facilities and can be used among patients with cognitive impairment.",[29,27,62,63,28,64],"Undisplaced Fracture","Treatment Complication","Arthroplasty Complications",[33,31,66,67,34],"treatment","hip arthroplasty","2024-11-28",{"date":70,"type":39},"2024-12-03",{"date":72,"type":39},"2021-06-20",{"date":74,"type":21},"2027-09-01",{"name":76,"class":46},"Uppsala University",1]