[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"internal-haemorrhoids\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:internal-haemorrhoids":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100529204","radiofrequency-ablation-vs-doppler-guided-haemorrhoidal-artery-ligation-in-the-treatment-of-haemorrhoidal-disease-100529204",false,"NCT06170736","Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease","Radiofrequency Haemorrhoidal Thermoablation Versus Doppler-guided Haemorrhoidal Artery Ligation With Mucopexy in the Treatment of Haemorrhoidal Disease: a Multicenter Randomized Non-inferiority Trial","RADIOLIGA","Inclusion Criteria:\n\n* Major patient,\n* With symptomatic Grade II or III haemorrhoidal disease,\n* Requiring surgical management,\n* Patient able to understand the protocol and having given written informed consent to participate in the study,\n* Patient affiliated to the social security system or entitled to it.\n\nExclusion Criteria:\n\n* Hemostasis disorders\n* Active external haemorrhoidal disease (thrombosis)\n* History of surgical procedure for treatment of haemorrhoids (instrumental treatment is not a contra-indication)\n* Associated proctological pathology (anal fissure, chronic suppuration, external rectal prolapse)\n* History of colorectal cancer\n* History of inflammatory bowel disease\n* History of rectal resection\n* Patient participating in another interventional clinical research protocol involving a drug or clinical investigation of a medical device\n* Patient who is pregnant, breastfeeding or able to procreate without effective contraception\\* at the time of inclusion\n* Patient under guardianship, curators or deprived of liberty.\n* Patient under court protection.\n\n  * oral contraceptive (pill), monthly vaginal ring, weekly transdermal patch, subcutaneous implant, intrauterine devices (IUD), or sterilisation.","ALL","18 Years","80 Years",{"count":21,"type":22},168,"ESTIMATED","INTERVENTIONAL",[25],"NA","Surgical treatment of grade II\u002FIII internal haemorrhoidal disease is indicated in the case of medical and\u002For instrumental treatment failure. Minimal invasive alternatives to haemorrhoidectomy have been introduced in the last decades to treat grade II\u002FIII haemorrhoids. Doppler-Guided haemorrhoidal artery ligation (DGHAL) represents a good therapeutic option in this condition with good short and mid-term outcomes but postoperative recurrence rates up to 35% at 5 years.\n\nRecently, a technique of radiofrequency ablation (RFA) has been introduced with promising outcomes. A recent systematic review reported a significant improvement of preoperative symptoms and a recurrence rate \\\u003C 5%.\n\nTo date, there is no study comparing DGHAL to RFA in the treatment of grade II\u002FIII haemorrhoids.\n\nThe aim of this study is to demonstrate the non-inferiority in terms of failure rate of haemorrhoidal radiofrequency ablation compared to Doppler-guided haemorrhoidal artery ligation, associated with mucopexy, in the treatment of grade II and III haemorrhoidal disease",[28,29,30],"Haemorrhoids","Internal Haemorrhoids","Grade II\u002FIII Haemorrhoids",[28,32,33],"Radiofrequency","Doppler-guided haemorrhoidal artery ligation","RECRUITING","2026-03-12",{"date":37,"type":38},"2026-03-13","ACTUAL",{"date":40,"type":38},"2024-02-21",{"date":42,"type":22},"2030-09-15",{"name":44,"class":45},"Centre Hospitalier Departemental Vendee","OTHER",18]