[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"internal-hemorrhoid\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:internal-hemorrhoid":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100524249","outcomes-and-quality-of-life-following-rectal-artery-embolization-for-bleeding-internal-hemorrhoids-100524249",false,"NCT06106269","Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids","Hemorrhoidal Embolization Trial-1 (HEMBO-1)","HEMBO-1","Inclusion Criteria:\n\n* Grade II or III hemorrhoidal disease as determined by a board-certified colorectal surgeon.\n* Persistent or recurrent symptoms following hygiene and dietary measures or medication.\n* Bleeding predominant ± pain symptoms.\n* Undergoing planned rectal artery embolization (RAE) per standard clinical care.\n* Male or female with age greater than 18 years, with the capacity and willingness to provide a written informed consent.\n* Negative pregnancy test (if applicable).\n\nExclusion Criteria:\n\n* Prior hemorrhoid surgery.\n* Grade IV hemorrhoidal disease.\n* Acute hemorrhoid complications.\n* Chronic anal or perianal fissures.\n* History of colorectal surgery or pelvic radiation.\n* Inflammatory bowel disease.\n* Portal hypertension or mesenteric venous congestion\u002Focclusion.\n* Inferior mesenteric artery (IMA) or internal iliac artery (IIA) stenosis or occlusion.\n* Contraindication to iodinated contrast.\n* Pregnant and\u002For breast-feeding subjects. A negative pregnancy test within 48 hours of the procedure per clinical care.","ALL","18 Years","90 Years",{"count":21,"type":22},20,"ESTIMATED","OBSERVATIONAL","This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.",[26],"Internal Hemorrhoid",[28,29,30],"Bleeding","Anemia","Hemorrhoid","RECRUITING","2026-06-15",{"date":34,"type":35},"2026-06-17","ACTUAL",{"date":37,"type":35},"2024-06-07",{"date":39,"type":22},"2026-12",{"name":41,"class":42},"Mayo Clinic","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":54,"studyType":23,"phases":4,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100643064","prospective-hemorrhoidal-embolisation-piles-registry-100643064","NCT07635784","Prospective HemorrhoIdaL EmboliSation (PILES) Registry","Creation Of a Prospective Registry For Hemorrhoid Artery Embolization At The Joint & Vascular Institute","PILES","Inclusion Criteria:\n\n* Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to medical therapy, referred for HAE.\n\nExclusion Criteria:\n\n* Pregnancy, coagulopathy, severe comorbidities, or inability to consent.",{"count":53,"type":22},1200,"5 Years","The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy.\n\nThe main question it aims to answer are:\n\n1\\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months?\n\nParticipants will:\n\n* Undergo HAE as part of their routine clinical care.\n* Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires.\n* Have safety outcomes tracked according to Society of Interventional Radiology guidelines.\n\nThere is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.",[30,57,58,59,26],"Internal Hemorrhoids","Hemorrhoid Bleeding","Hemorrhoidal Bleeding",[61,62,63],"bleeding","hemorrhoids","internal hemorrhoids","2026-06-10",{"date":66,"type":35},"2026-06-12",{"date":68,"type":35},"2026-01-18",{"date":70,"type":22},"2032-01",{"name":72,"class":73},"Joint & Vascular Institute","INDUSTRY",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":43},"100375488","caes-for-internal-hemorrhoids-and-rectal-prolapse-100375488","NCT04169152","CAES for Internal Hemorrhoids and Rectal Prolapse","Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse: a National Multi-centre Prospective Cohort Study","Inclusion Criteria:\n\n1. Grade I-III internal hemorrhoids (with or without external hemorrhoids) or\u002Fand recal prolapse.\n2. Patients with bowel preparation.\n\nExclusion Criteria:\n\n1. History of anoscopic\u002Fendoscopic sclerotherapy.\n2. Acute thrombotic hemorrhoids or grade IV internal hemorrhoids.\n3. Anal stenosis, perianal and perirectal abscess, anal fissure, fistula, fecal incontinence and other severe complications (such as severe anal pain).\n4. Inflammatory bowel disease.\n5. Full-thickness rectal prolapse through the anus.\n6. Acute diarrhea in the past 24 hours.\n7. Hypertensive with uncontrolled blood pressure.\n8. Cerebrovascular accident.\n9. Blood coagulation dysfunction.\n10. Pregnant women.\n11. Mental disorders.\n12. Decompensated cirrhosis.",{"count":82,"type":22},10000,"Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy. However, the long-term efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse are still not clear due to the lack of large sample studies. Therefore, a nationwide multi-center, large sample, prospective and cohort study was designed to evaluate the efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse, to provide reliable evidence for popularization of this minimally invasive technology.",[26,85],"Rectal Prolapse",[87,26,85],"Cap-assisted endoscopic sclerotherapy","2024-04-01",{"date":90,"type":35},"2024-04-02",{"date":92,"type":35},"2019-12-30",{"date":94,"type":22},"2028-06-30",{"name":96,"class":42},"Faming Zhang"]