[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intertransverse-process-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intertransverse-process-block":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,47,76,97,119,140,164,188],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100641947","intertransverse-process-block-versus-m-tapa-block-after-laparoscopic-cholecystectomy-100641947",false,"NCT07589491","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic sleeve gastrectomy\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[27,28,29,30,31],"Intertransverse Process Block","Mtapa Block","Laparoscopic Cholecystectomy","Postoperative Pain","Regional Anaesthesia",[33,34],"M-TAPA","ITP","NOT_YET_RECRUITING","2026-06-15",{"date":38,"type":39},"2026-06-16","ACTUAL",{"date":41,"type":21},"2026-11-15",{"date":43,"type":21},"2027-10-30",{"name":45,"class":46},"Antalya City Hospital","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100637166","analgesic-efficacy-of-intertransverse-process-block-versus-erector-spinae-plane-block-100637166","NCT07583602","Analgesic Efficacy of Intertransverse Process Block Versus Erector Spinae Plane Block","Analgesic Efficacy of Intertransverse Process Block Versus Erector Spinae Plane Block in Robotic Colorectal Surgery: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective robotic colorectal surgery\n* Body mass index (BMI) between 18 and 35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\\u003C18 or \\>35 kg\u002Fm²",{"count":55,"type":21},50,[24],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITP) and the Erector Spinae Plane (ESP) block in patients undergoing Robotic Colorectal Surgery. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient and surgeon satisfaction assessed using a Likert scale, and quality of recovery assessed using the QoR-15 questionnaire, and incedence of postoperative nausea and vomiting.",[59,60,27,30],"Robotic Colorectal Surgery","Erector Spine Plane Block",[62,63,64,65,66],"esp","ıtp","robotic surgery","colorectal surgery","regional block","2026-05-17",{"date":69,"type":39},"2026-05-20",{"date":71,"type":21},"2026-08-30",{"date":73,"type":21},"2028-04-30",{"name":45,"class":46},1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":83,"minAge":17,"maxAge":18,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":4},"100640445","intertransverse-process-block-versus-m-tapa-block-after-laparoscopic-hysterectomy-100640445","NCT07599787","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic hysterectomy\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","FEMALE",{"count":20,"type":21},[24],"This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic hysterectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[27,28,88,30,31],"Laparoscopic Hysterectomy",[33,34],"2026-05-15",{"date":69,"type":39},{"date":93,"type":21},"2026-11-18",{"date":95,"type":21},"2027-11-30",{"name":45,"class":46},{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":105,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":4},"100637643","intertransverse-process-block-versus-external-oblique-intercostal-plane-block-after-laparoscopic-sleeve-gastrectomy-100637643","NCT07591116","Intertransverse Process Block Versus External Oblique Intercostal Plane Block After Laparoscopic Sleeve Gastrectomy","Intertransverse Process Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic sleeve gastrectomy\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²",{"count":20,"type":21},[24],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal External Oblique Intercostal Plane Block (EOIPB) in patients undergoing laparoscopic sleeve gastrectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[27,108,109,31,30],"External Oblique Intercostal Plane Block","Sleeve Gastrectomy",[34,111],"EOIPB","2026-05-09",{"date":90,"type":39},{"date":115,"type":21},"2026-12-15",{"date":117,"type":21},"2027-12-30",{"name":45,"class":46},{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":126,"briefSummary":127,"conditions":128,"keywords":130,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":134,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":75},"100638217","intertransverse-process-block-versus-subcostal-transversus-abdominis-plane-block-after-laparoscopic-sleeve-gastrectomy-100638217","NCT07591129","Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy","Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Controlled Trial",{"count":20,"type":21},[24],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal Transversus Abdominis Plane Block (TAPB) in patients undergoing laparoscopic sleeve gastrectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[27,129,109,30,31],"Subcostal Transverse Abdominis Plane Block",[34,131,132,133],"TAP","PAİN","SLEEVE GASTRECTOMİ",{"date":90,"type":39},{"date":136,"type":21},"2026-12-30",{"date":138,"type":21},"2028-05-30",{"name":45,"class":46},{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":147,"targetDuration":4,"studyType":22,"phases":149,"briefSummary":150,"conditions":151,"keywords":154,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":75},"100631747","comparison-of-intertransverse-process-and-erector-spinae-plane-blocks-in-acute-postoperative-analgesia-management-for-laparoscopic-cholecystectomy-patients-100631747","NCT07504705","Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients","Comparison of Intertransverse Process and Erector Spinae Plane Blocks in Acute Postoperative Analgesia Management for Laparoscopic Cholecystectomy Patients: A Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Undergoing elective laparoscopic cholecystectomy\n* Body mass index (BMI) between 18 and 35 kg\u002Fm²\n* American Society of Anesthesiologists (ASA) physical status score of I-III\n* Ability to provide written and verbal informed consent\n\nExclusion Criteria:\n\n* Coagulopathy or use of anticoagulant medications\n* Infection at the injection site\n* Allergy to local anesthetics\n* Pregnancy or breastfeeding\n* Chronic opioid use or analgesic dependence\n* Severe cardiopulmonary disease or psychiatric disorders\n* Previous regional block performed within the last 24 hours\n* Patients requiring emergency surgery\n* Cases converted from laparoscopic surgery to open surgery",{"count":148,"type":21},110,[24],"Laparoscopic cholecystectomy is considered the gold standard for the surgical treatment of benign gallbladder diseases; however, despite its minimally invasive nature, a significant proportion of patients experience substantial early postoperative pain, which impacts patient comfort and the duration of hospital stay. The current PROSPECT review and previous studies emphasize that this pain is multifactorial-comprising somatic, visceral, and phrenic nerve-mediated shoulder-tip components-and therefore advocate for an opioid-sparing multimodal analgesic approach. Within this framework, first-line recommendations include paracetamol, NSAIDs\u002FCOX-2 inhibitors, dexamethasone, and local anesthetic infiltration of the surgical site and\u002For intraperitoneal cavity, alongside appropriate regional blocks; opioids should be reserved solely for rescue analgesia.\n\nUltrasound-guided regional anesthesia blocks are increasingly utilized for acute visceral pain conditions, such as renal colic. The Erector Spinae Plane Block (ESPB) is an interfacial block performed in the thoracic paraspinal region, and it is hypothesized that its extensive spread may influence somatic and, to some extent, visceral pain pathways. Nevertheless, anatomical and clinical studies report inconsistent effects of ESPB on visceral pain, noting that local anesthetics may not consistently reach the paravertebral space, thereby leading to variable block efficacy.\n\nConsequently, the Intertransverse Process Block (ITPB), which targets a plane anatomically closer to the paravertebral space, has been described in recent years as an alternative technique. ITPB is performed by injecting local anesthetic into the interfacial space adjacent to the retro-superior costotransverse ligament; it is reported to carry a low risk of complications as it does not require direct orientation toward the pleura or neuraxial structures. Clinical trials indicate that ITPB provides analgesic efficacy comparable to paravertebral blocks in both thoracic and abdominal surgeries and reduces opioid consumption. Furthermore, anatomical studies suggest that the probability of local anesthetic spread into the paravertebral space is higher with ITPB than with ESPB.\n\nHowever, a randomized controlled trial comparing ESPB and ITPB in patients undergoing laparoscopic cholecystectomy is currently lacking in the literature. Therefore, the present study was designed to address this gap.",[152,153,27],"Acut Postoperative Pain","Erector Spinae Plane Block",[29,153,27,30],"2026-04-08",{"date":157,"type":39},"2026-04-13",{"date":159,"type":21},"2026-05-01",{"date":161,"type":21},"2027-05-25",{"name":163,"class":46},"Konya City Hospital",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":174,"briefSummary":175,"conditions":176,"keywords":179,"overallStatus":181,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":185,"leadSponsor":187,"locationsCount":75},"100618717","intertransverse-process-block-for-postoperative-analgesia-after-thoracotomy-and-lobectomy-100618717","NCT07335250","Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy","Postoperative Pain Control With Intertransverse Process Block in Patients Undergoing Thoracotomy With Lobectomy","Inclusion Criteria:\n\n* Provision of written informed consent\n\nAge between 18 and 85 years\n\nASA Physical Status classification I-III\n\nElective thoracotomy with planned unilateral lobectomy\n\nAnticipated hospital stay of at least one night\n\nExpected requirement for parenteral opioid analgesia for at least 24 hours postoperatively\n\nAbility to operate an intravenous patient-controlled analgesia (PCA) device\n\nExclusion Criteria:\n\n* Patients undergoing emergency surgery\n\nPresence of infection or open wound at the injection site\n\nCoagulopathy\n\nHepatic or renal failure\n\nPatients undergoing reoperation\n\nPatients with missing or incomplete data\n\nPregnancy or lactation\n\nTracheal malformation or tracheostomy\n\nChronic opioid use (≥30 days within the last 3 months, ≥15 mg\u002Fday morphine equivalent)\n\nPatients exceeding the maximum safe local anesthetic dose based on weight (2.5 mg\u002Fkg, max 150 mg)\n\nPatients who refuse data privacy consent will be excluded from the study","85 Years",{"count":173,"type":21},66,[24],"This prospective, randomized, triple-blind, placebo-controlled clinical trial will investigate the effectiveness of the intertransverse process block (ITPB) for postoperative analgesia in patients undergoing elective thoracotomy with unilateral lobectomy. The study will be conducted at a single tertiary center in accordance with the principles of the Declaration of Helsinki, and written informed consent will be obtained from all participants.\n\nPatients will be randomized in a 1:1 ratio to receive either ultrasound-guided ITPB with 0.5% bupivacaine or placebo (normal saline) prepared in identical syringes to ensure allocation concealment. The block will be performed by an experienced anesthesiologist immediately after surgery and before emergence from anesthesia. Both groups will receive standardized general anesthesia, multimodal perioperative analgesia, and postoperative intravenous morphine patient-controlled analgesia (PCA).\n\nThe trial aims to evaluate the analgesic efficacy and opioid-sparing effect of ITPB while maintaining safety and adherence to routine clinical practice. Outcomes will include postoperative pain scores, opioid consumption, rescue analgesia requirement, and adverse events.",[177,178,27],"Acute Postoperative Pain","Thoracotomy Surgery",[27,180,177],"Thoracotomy Lobectomy","RECRUITING",{"date":183,"type":39},"2026-04-09",{"date":155,"type":39},{"date":186,"type":21},"2027-03-01",{"name":163,"class":46},{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":4},"100589640","intertransverse-process-block-for-quality-of-recovery-post-open-hepatectomy-100589640","NCT06957041","Intertransverse Process Block for Quality of Recovery Post-Open Hepatectomy","Effect of Intertransverse Process Block on the Quality of Recovery Post-Open Hepatectomy: A Pilot Non-Randomised Study of Intervention","ITPB QoR","Inclusion Criteria:\n\n\\- Adult patients aged 18-75 years of ASA I - III physical status classification undergoing open hepatectomy for benign or malignant liver lesion.\n\nExclusion Criteria:\n\n* Patient refusal\n* Patients who are unable to comprehend the QoR15 form\n* Local or systemic infection\n* Coagulopathy leading to absolute contraindication to regional anesthesia\n* Contraindication to local anaesthetics (LA) such as LA allergy","75 Years",{"count":198,"type":21},20,[24],"The study aims to assess the analgesic efficacy of the ITPB at the retro-SCTL space in patients undergoing major open hepatectomy surgery. This is assessed by:\n\nPrimary Objective:\n\nPrimary outcome measure:\n\n● Assessing the quality of recovery 15 (QoR15) score at 24 and 48 hours\n\nSecondary outcome measure:\n\n* Number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge\n* Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow.\n* Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours\n* Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU)\n\nHypothesis:\n\nThe investigators hypothesize that the application of ITPB targeting the retro-SCTL space in patients undergoing open hepatectomy will improve overall quality of recovery and pain score.",[202,27,203],"Hepatectomy","Quality of Recovery (QoR-15)","2025-04-25",{"date":206,"type":39},"2025-05-04",{"date":208,"type":21},"2025-05-01",{"date":210,"type":21},"2026-10-01",{"name":212,"class":46},"Chinese University of Hong Kong"]