[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intervention":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,42,76,103,129,155,180,202,230,258,285,313,339,371,397,422,443,465,493,515],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":39,"locationsCount":4},"100594886","the-effects-of-cognitive-motor-dual-task-intervention-on-fall-prevention-among-older-adults-100594886",false,"NCT07025278","The Effects of Cognitive-motor Dual-task Intervention on Fall Prevention Among Older Adults","The Effects and Mechanisms of Game-based Cognitive-motor Dual-task Intervention on Fall Prevention Among Older Adults","Inclusion Criteria:\n\n1. Age ≥ 65 years old;\n2. Able to walk independently for at least 10 meters without obvious pain or difficulty;\n3. Free from lower limb and foot deformities, wounds, ulcers, or other diseases, and capable of wearing flexible devices;\n4. Scored as low or moderate fall risk on the Morse Fall Risk Assessment Scale;\n5. Scored \\> 40 points on the Berg Balance Scale and \\\u003C 20 seconds on the Time Up and Go Test (TUG);\n6. Scored ≥ 21 points on the Mini-Mental State Examination (MMSE);\n7. With an educational level of primary school or above, able to correctly understand instructions and make corresponding responses;\n8. Without diseases that severely affect cognitive and motor functions, including cardiovascular diseases (such as uncontrolled hypertension, heart failure, etc.), neurological diseases (such as Parkinson's disease, stroke, epilepsy, etc.), musculoskeletal diseases (such as severe arthritis, recent fractures, etc.), etc.;\n9. Normal vision and hearing or corrected to normal, without affecting the understanding of instructions and participation in interventions;\n10. Conscious and able to understand the test requirements;\n11. Able to understand and sign the informed consent form voluntarily, and willing to cooperate in completing the research procedures.\n\nExclusion Criteria:\n\n1. Must rely on assistive walking devices or others to walk;\n2. Individuals with color vision disorders, including various types of color blindness and color weakness;\n3. Unable to correctly perform addition and subtraction operations;\n4. Those allergic to the materials of research equipment;\n5. Currently participating in other research or intervention projects that may affect the effectiveness of this intervention.",true,"ALL","65 Years",{"count":20,"type":21},125,"ESTIMATED","INTERVENTIONAL",[24],"NA","1. Develop an evidence-based dual-task intervention programme incorporating gamification for fall risk reduction in older adults.\n2. Examine the effects of the gamified dual-task intervention on fall risk in older adults.\n3. Elucidate the underlying mechanisms of the optimal gamified dual-task intervention programme in reducing falls in older adults.",[27,28,29,30],"ELDERLY PEOPLE","Cognitive-motor Dual-task","Fall Prevention","Intervention","NOT_YET_RECRUITING","2026-06-25",{"date":34,"type":35},"2026-06-29","ACTUAL",{"date":37,"type":21},"2027-03-31",{"date":37,"type":21},{"name":40,"class":41},"Jinyao Wang","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100624727","oral-health-education-for-pregnant-women-100624727","NCT07413393","Oral Health Education for Pregnant Women","Knowledge of Oral Health in Pregnant Women: Effect of a Short Educational Intervention","Inclusion Criteria:\n\n* Women aged 18-45 who have recently given birth to healthy babies, either vaginally or by cesarean section.\n* Ability to understand and speak Spanish.\n\nExclusion Criteria:\n\n* Complications during pregnancy or delivery.\n* Newborns with major birth defects.\n* Participants who do not provide informed consent.","FEMALE","18 Years","45 Years",{"count":53,"type":21},300,[24],"The goal of this research is to investigate oral health knowledge in pregnant women receiving care at Hospital La Fe and to see whether a one-time informational intervention improves this knowledge. The main questions this research aims to answer are:\n\nWhat is the level of oral health knowledge among pregnant women attending Hospital La Fe?\n\nDoes a one-time informational intervention, delivered through a printed leaflet, improve oral health knowledge during pregnancy?\n\nWhat factors are related to differences in oral health knowledge among pregnant women?\n\nParticipants are pregnant women receiving care at Hospital La Fe. They will:\n\nComplete a questionnaire about their oral health knowledge.\n\nReceive a printed informational leaflet about oral health during pregnancy.\n\nComplete the same questionnaire again after a period of time to see if their knowledge has changed.\n\nResearchers will compare answers before and after the leaflet is provided to see whether oral health knowledge improves. They will also explore which personal or social factors are linked to different levels of oral health knowledge.",[57,58,59,30],"Knowledge","Oral Health","Pregnant Women",[61,62,63,64],"oral health","knowledge","pregnant","improvement","RECRUITING","2026-06-05",{"date":68,"type":35},"2026-06-09",{"date":70,"type":35},"2026-02-15",{"date":72,"type":21},"2026-07-30",{"name":74,"class":41},"University of Valencia",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":75},"100562119","swallowing-difficulties-in-people-over-60-years-prevalence-degree-of-difficulty-and-intervention-100562119","NCT06599021","Swallowing Difficulties in People Over 60 Years: Prevalence, Degree of Difficulty and Intervention","Inclusion Criteria:\n\n* Participation in SCAPIS2\n* Swallowing dysfunction according to timed water swallow test or\n* Swallowing dysfunction according to self-report\n\nExclusion Criteria:\n\n* Severely impaired intellectual abilities.\n* Inability to consent to inclusion in the study.\n* Inability to answer written questionnaires in Swedish\n\nInclusion of non-dysphagia control cohort: No signs of aspiration, slow swallowing (\\<10 ml\u002Fsec) or self-rated difficulties with eating and swallowing in sub-study SCAPIS2",{"count":83,"type":21},99,[24],"Participants included in SCAPIS2 (Swedish Cardio Pulmonary bioimage study) are screened regarding swallowing difficulty using a timed water swallow test. Participants who show signs of swallowing difficulty (dysphagia) are included in the present study, which encompasses s flexible endoscopic evaluation of swallowing function (FEES). Participants showing a moderate-severe dysphagia are randomized into one of three intervention groups: muscle strengthening training, skill-based swallowing training and a control group who will receive compensatory treatment. The study is expected to improve diagnostics and treatment of swallowing difficulties in an ageing population.",[87,30,88],"Dysphagia","Ageing",[87,90,91,92,93],"Age-related dysphagia","Health-related quality of life","Dysphagia intervention","Dysphagia characteristics","2026-04-22",{"date":96,"type":35},"2026-04-27",{"date":98,"type":35},"2024-12-01",{"date":100,"type":21},"2028-04",{"name":102,"class":41},"Lisa Tuomi",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":117,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":128},"100555706","effect-of-developmental-care-on-very-low-birth-weight-infants-100555706","NCT06515574","Effect of Developmental Care on Very Low Birth Weight Infants","Effect of Developmental Care on Very Low Birth Weight Infants: a Stepped-wedge Cluster Randomised Trial","Inclusion Criteria\n\n1. Birth weights less than 1500 g\n2. Admitted or transported to a level III NICU within 24h of birth\n3. OI\\>30\n\nExclusion Criteria:\n\n1. Severe congenital malformations\n2. various chromosomal disorders\n3. genetic metabolic diseases,\n4. severe neurological disorders","0 Days","30 Days",{"count":113,"type":21},1600,[24],"The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are:\n\n* Does developmental care shorten the length of hospital stay in the very low birth weight infants?\n* Does developmental care increase the opportunity of family centered care in the very low birth weight infants? The clinical trial will use a 36-month stepped-wedge cluster-randomised trial conducted across 40 Neonatal intensive care units . A developmental care bundle will be tailored to meet the identified needs of participating NICUs.",[30],[118],"developmental care","2026-03-13",{"date":121,"type":35},"2026-03-16",{"date":123,"type":35},"2024-08-30",{"date":125,"type":21},"2027-12-01",{"name":127,"class":41},"Children's Hospital of Fudan University",2,{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":139,"briefSummary":140,"conditions":141,"keywords":142,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":75},"100591325","family-navigator-plus-for-foster-parents-100591325","NCT06978959","Family Navigator Plus for Foster Parents","Building Capacity for Youth Mental Wellness: Feasibility and Acceptability for a Mental Health Family Navigator Model for Foster Parents","FN+","Inclusion Criteria:\n\n* Foster parent of a youth between the ages of 6 to 17 with mental health needs\n* Parent adopted child from foster care\n* Living in Illinois, United States\n* English or Spanish speaking\n* Has access to internet and videoconferencing\n\nExclusion Criteria:\n\n\\- Participated in the FN+ Focus Groups or PROACTIVE Parent Pilot Study",{"count":138,"type":21},12,[24],"The investigators have designed a 5-week Family Navigator Plus (FN+) educational program to support foster parents in better understanding their youth's mental health needs and in finding mental health services. The purpose of this interventional study is to assess the the program's acceptability (e.g., satisfaction, barriers to participation, and burden), utility (e.g., how useful foster parents found the program to be), and feasibility (e.g., number referred who meet eligibility, time to complete assessments, self-reported feasibility). The investigators hypothesize that our program will be acceptable, useful, and feasible for foster parents of youth with mental health needs.",[30],[143,144,145],"foster parents","family navigator","psychoeducation","2026-01-23",{"date":148,"type":35},"2026-01-27",{"date":150,"type":35},"2026-01-12",{"date":152,"type":21},"2028-12-31",{"name":154,"class":41},"Northwestern University",{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":16,"sex":17,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":22,"phases":166,"briefSummary":167,"conditions":168,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":75},"100446324","connecting-families-100446324","NCT05091957","Connecting Families","CONNECTING FAMILIES: A Randomized Controlled Trial of Primary Care Poverty Screening and Financial Support Navigation for Families of Young Children","Inclusion Criteria:\n\n* Parents of children (younger than 3 years) attending a regularly scheduled primary care visit.\n* Parents respond affirmatively to the question \"Do you ever have difficulty making ends meet at the end of the month?\"\n* Informed parental consent. Only one child will be enrolled per family. For families with more than one child, we will enroll the youngest eligible child, since literature suggests that impact of reducing family stress may be greater at younger ages; for multiple births, one child will be randomly selected for inclusion.\n\nExclusion Criteria:\n\n1. Parents without legal status in Canada, as they are not eligible for many Canadian social programs.\n2. Families who are receiving system navigation support, such as from a social worker or public health nurse, or who have received system navigation support within one year prior to enrolment.\n3. Child with a previously diagnosed developmental disorder, genetic, chromosomal or syndromic condition.\n4. Child born prematurely (gestational age less than 32 weeks).","1 Day","3 Years",{"count":165,"type":21},80,[24],"Living in poverty has a profound negative impact on parenting stress and children's health. When poverty occurs early in childhood and continues for a long time, the impact on child health can be lifelong. Child poverty is common, affecting about 20% of Canadian children. Many low income families may not be receiving all the social benefits for which they are eligible. There are calls for primary care providers to ask patients if they have difficulty making ends meet at the end of the month and to intervene if poverty is identified, but it is not known if intervening can improve parent's and children's health. This study will test whether a Community Support Worker who helps families with young children navigate the social service system by reviewing social needs (like food, housing or energy insecurity) and income supports can lead to increased family income, reduced parenting stress and an improvement in their child's health. The Community Support Worker will help families complete income tax, apply for benefits and community supports for which they are eligible. The investigators will also study the effect of this intervention on health care utilization. Our study will be conducted in Toronto and Kingston in primary care practices participating in the TARGet Kids! primary care research network. Results from this study will help health care providers and policy makers understand whether Community Support Workers are an effective way to integrate the health and social service systems to improve parent and child health.",[169,170,30],"Poverty","Primary Care","2026-01-11",{"date":173,"type":35},"2026-01-13",{"date":175,"type":35},"2022-05-17",{"date":177,"type":21},"2026-04",{"name":179,"class":41},"Queen's University",{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":186,"eligibilityCriteria":187,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":188,"targetDuration":4,"studyType":22,"phases":190,"briefSummary":191,"conditions":192,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":194,"lastUpdatePostDateStruct":195,"startDateStruct":197,"completionDateStruct":199,"leadSponsor":200,"locationsCount":75},"100617031","exploring-resistance-exercise-training-plus-high-intensity-interval-training-rehiit-as-cancer-prehabilitation-100617031","NCT07313332","Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation","Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation: A Healthy Control Group Pilot Study","ReHIIT_CON","Inclusion Criteria:\n\n* Participant is willing and able to give informed consent for participation in the study.\n* Availability and willingness to attend the Royal Derby Hospital site for a minimum of 8 exercise sessions and 2 assessment sessions across the study period.\n\nExclusion Criteria:\n\n* BMI \\\u003C18 or \\>35 kg\u002Fm2\n* Known active cance\n* Known metabolic disease\n* Current known neurological or musculoskeletal conditions (e.g. epilepsy)\n* Active known cardiovascular, cerebrovascular or respiratory disease - e.g:\n* Uncontrolled hypertension (systolic BP \\> 160 mmHg or diastolic BP \\>100 mmhg)\n* Myocardial infarction within the last 6 months or unstable angina\n* Heart failure (New York Heart association Class III\u002FIV)\n* Arrhythmia\n* Right to left cardiac shunt\n* Aneurysm of a named blood vessel\n* COPD\n* Pulmonary hypertension\n* Exercise-induced or brittle asthma\n* Previous stroke\u002Ftransient ischaemic attack\n* Abnormal ECG results (at the discrepancy of the study doctor)\n* Patients who are unable to undergo CPET based on ATS\u002FACSS guidelines \\^\n* Pre-existing clotting disorder known to the participant or anticoagulant use\n* Family history of severe bleeding requiring medical intervention\n* Participation in a research study in the last 3 months involving invasive procedures or an inconvenience allowance (ALL UoN FMHS UREC approved studies)\n* Pregnant or breastfeeding",{"count":189,"type":21},14,[24],"Colorectal cancer is the fourth most common cancer in the UK. Prehabilitation, including exercise, can improve recovery from surgery. This pilot study investigates the combined effects of resistance and high-intensity interval training (ReHIIT) in healthy adults to establish baseline physiology and responses for comparison with cancer patients",[193,30],"Healthy Adult Male and Female Volunteers","2025-12-16",{"date":196,"type":35},"2025-12-31",{"date":198,"type":21},"2026-01-01",{"date":125,"type":21},{"name":201,"class":41},"University of Nottingham",{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":16,"sex":49,"minAge":4,"maxAge":4,"enrollmentInfo":210,"targetDuration":4,"studyType":22,"phases":212,"briefSummary":213,"conditions":214,"keywords":215,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":221,"lastUpdatePostDateStruct":222,"startDateStruct":224,"completionDateStruct":226,"leadSponsor":228,"locationsCount":4},"100600269","effect-of-culturally-tailored-health-education-on-postnatal-care-use-among-postpartum-women-in-ethiopia-100600269","NCT07095296","Effect of Culturally Tailored Health Education on Postnatal Care Use Among Postpartum Women in Ethiopia","Effect of a Culturally Tailored Health Education Intervention Based on Social Cognitive Theory and the Theory of Planned Behavior on Postnatal Care Utilization Among Postpartum Women in Ethiopia","ECTHE","Cluster-Level Eligibility Criteria:\n\nTo be eligible for inclusion, clusters must meet the following criteria:\n\n* A catchment population size of at least 5,000 people\n* An average of more than 50 antenatal care (ANC) visits per month\n* Location in a peri-urban area to facilitate participant follow-up\n\nIndividual-Level Eligibility Criteria (for mothers):\n\n* Gestational age between 20 and 24 weeks at the time of enrollment\n* Residence within one hour's travel distance from the selected health facility\n\nIndividual-Level Exclusion Criteria:\n\n* Mothers who plan to relocate from the selected cluster area before or shortly after delivery\n* Mothers who do not speak either Afan Oromo or Amharic, as these are the languages used for delivering the intervention.\n* Mothers who have already completed all recommended postnatal care visits during their most recent previous birth",{"count":211,"type":21},864,[24],"This clinical study aims to find out if a redesigned health education program-one that respects local cultural beliefs and is based on well-known behavior change theories-can help improve how well mothers care for their newborns and how often they use postnatal care services. The main hypothesis is that culturally tailored health education provided by trained midwives will lead to: 1. Increased use of postnatal care services by mothers after childbirth, and 2. Improved knowledge among mothers about how to care for their newborns.\n\nIn the study, midwives will first be trained in how to provide this culturally appropriate health education. Then, the trained midwives will deliver four health education sessions-once a month-to pregnant women during their regular antenatal (before birth) visits at health facilities.",[30],[216,217,218,219,220],"PNC","Counseling","Health education","Newborn care","Cluster Randomized Trial","2025-12-01",{"date":223,"type":35},"2025-12-03",{"date":225,"type":21},"2025-12",{"date":227,"type":21},"2026-07",{"name":229,"class":41},"Swiss Tropical & Public Health Institute",{"id":231,"slug":232,"hasResults":11,"nctId":233,"briefTitle":234,"officialTitle":234,"acronym":4,"eligibilityCriteria":235,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":236,"targetDuration":4,"studyType":22,"phases":238,"briefSummary":239,"conditions":240,"keywords":243,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":4},"100611384","the-effect-of-a-digital-board-game-based-psychological-empowerment-program-on-nurses-psychological-empowerment-levels-job-satisfaction-and-innovative-behaviors-100611384","NCT07239882","The Effect of a Digital Board Game-Based Psychological Empowerment Program on Nurses' Psychological Empowerment Levels, Job Satisfaction, and Innovative Behaviors","Inclusion Criteria:\n\n* Being between the ages of 18 and 45 (although there are differing opinions in the literature on the age limit, the 45-year-old age limit encompasses a period when the effects of aging are more pronounced),\n* Voluntarily participating in the study and having given written consent,\n* Working a mix of day and night shifts (arrangements such as working only during the day, only at night, or with maternity leave will be excluded),\n* Not receiving any other psychological training or therapy during the study dates,\n* Not holding any additional job,\n* Not participating in any additional program,\n* Having at least one year of work experience,\n* Not having a physical or mental illness that would prevent participation in the program,\n* Having a bachelor's degree,\n* Working as a nurse in the relevant institution during the study dates,\n* Possessing and being able to use a computer, mobile phone, etc., to play digital games and participate in online group workshops and online training presentations.\n\nExclusion Criteria:\n\n* Not meeting inclusion criteria\n\n  • Exclusion criteria from the study:\n* Failure to attend 2 or more sessions (attending less than 70% of the sessions),\n* Withdrawal from the study voluntarily,\n* Developing health problems that prevent participation after starting the program,\n* Failure to complete all six sessions for various reasons (illness, moving, etc.).",{"count":237,"type":21},50,[24],"Psychological empowerment is defined as nurses' perceptions of their professional roles as meaningful, their ability to effectively perform their duties, their level of participation in organizational decision-making processes, and their perceptions of their professional productivity. In occupational groups with high stress levels, such as nursing, psychological empowerment plays a crucial role in maintaining individual and organizational well-being. Research indicates that nurses' levels of psychological empowerment are moderate and that there is a need for enhancing interventions.\n\nThe purpose of this study is to evaluate the effects of a digital board game-based psychological empowerment program on nurses' psychological empowerment levels, job satisfaction, and innovative behaviors. The research was designed with a pretest-posttest randomized controlled experimental design. The study sample will consist of nurses working in a university hospital. Participants will be selected according to specified inclusion and exclusion criteria, and data will be collected using a Personal Information Form, the Psychological Empowerment Scale, the Job Satisfaction Scale, and the Innovative Behavior Scale. The \"digital board game-based psychological empowerment program\" will be structured based on Kanter and Spreitzer's empowerment theories. The Ministry of Health's 2021 \"Guide to Core Competencies in Nursing,\" the Psychological Empowerment Scale sub-dimensions, and studies on psychological empowerment in nursing in the literature will be considered in the preparation of the training content. The final version of the program will be completed following expert opinions. The program will consist of 6-week sessions. Each session is planned as two parts: (1) online empowerment training and (2) online group workshops. The group workshops will include topic-specific question-and-answer activities, group discussions, and digital board game applications appropriate to the session theme. Re-measurements (post-tests) will be conducted in the first and third months following the intervention. The control group will not receive any active intervention and will be subjected to the same assessment at the same time intervals as the intervention group. The control group will receive a booklet containing the training content at the end of the study. The data obtained will be analyzed using an independent samples t-test. The study results indicate a significant increase in nurses' psychological empowerment levels and an improvement in their job satisfaction and innovative behaviors in the intervention group. While numerous studies on the psychological empowerment of nurses exist in the literature, structured, long-term psychological empowerment programs and intervention studies are limited. The unique aspect of this study is the development and implementation of an innovative game-based intervention program to contribute to the psychological empowerment of nurses.",[241,30,242],"Digital Board Games","Psychological Empowerment Program",[244,245,246,241,247,248],"Nursing","Psychological Empowerment","Job Satisfaction","Innovative Behavior","intervention","2025-11-16",{"date":251,"type":35},"2025-11-20",{"date":253,"type":21},"2025-12-15",{"date":255,"type":21},"2026-10-15",{"name":257,"class":41},"Akdeniz University",{"id":259,"slug":260,"hasResults":11,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":4,"eligibilityCriteria":264,"healthyVolunteers":11,"sex":17,"minAge":265,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":22,"phases":269,"briefSummary":270,"conditions":271,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":75},"100468459","comparing-telehealth-to-in-person-a-combined-metacognitive-training-in-veterans-with-mtbiptsd-100468459","NCT05380050","Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI\u002FPTSD","Comparing the Effectiveness of Telehealth to In-person Delivery of a Combined Metacognitive and Attention Training in Veterans With mTBI\u002FPTSD","Inclusion Criteria:\n\n* Veterans who have served in OIF-OEF-OND and have been diagnosed with both a mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) based on the joint criteria of the Veterans' Affairs and Department of Defense (VA \\& DoD).\n* Latest mTBI occurred at least 6 months prior to study enrollment.\n* Attention deficit of 1.5 SD below the mean of the RBANS attention index.\n* Family member or friend that is willing to complete a questionnaire.\n* Access to a home computer, or smartphone with internet access.\n\nExclusion Criteria:\n\n* History of pre-morbid learning disability.\n* History of psychiatric diagnosis sufficiently severe to have resulted in inpatient hospitalization.\n* Neurological disease unrelated to TBI (seizure disorder, stroke).\n* Score \\\u003C 90 on National Adult Reading Test (NART).\n* Failure of validity testing on the Test of Memory Malingering (TOMM).\n* Reported alcohol or substance abuse within the past year.\n* Reported involvement in current litigation related to injury.\n* Recent change of medications for seizures, depression, or memory.\n* Currently enrolled in other cognitive therapy that cannot be discontinued.\n* Does not speak English fluently.\n* Not competent to provide consent (also, not able to demonstrate understanding of expectations of study and potential risks of participation).\n* Uncontrolled, acute medical or psychiatric condition as indicated by the participant or observed by the research team member that would make it unsafe to participate in the research activities, i.e. precautions for active homicidal\u002Fsuicidal intent, active psychosis, or acute symptoms requiring immediate medical attention.","30 Years","55 Years",{"count":268,"type":21},63,[24],"Veterans with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) commonly experience cognitive impairments including attention and executive function deficits that interfere with their ability to engage in productive personal and social activities. Of the limited interventions available to address cognition, none rigorously train attention beyond strategy management. This study will evaluate an innovatively combined strategy training known as Goal Management Training plus computerized attention training in Veterans with mTBI\u002FPTSD. Preliminary testing suggests an effectiveness in improving problem solving, attention and functional tasks in a small number of Veterans. Considering these promising results, cost effectiveness, and the demand for access to care from Veterans living in rural areas, a Randomized Controlled Trial will determine and compare the effects of this treatment, administered either in-person or via telehealth, on executive function, attention, other aspects of cognition and real life functional tasks.",[272,273,274,30],"Brain Injury","Cognition","PTSD","2025-10-16",{"date":277,"type":35},"2025-10-21",{"date":279,"type":35},"2022-11-01",{"date":281,"type":21},"2026-10-31",{"name":283,"class":284},"VA Office of Research and Development","FED",{"id":286,"slug":287,"hasResults":11,"nctId":288,"briefTitle":289,"officialTitle":289,"acronym":4,"eligibilityCriteria":290,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":291,"targetDuration":4,"studyType":22,"phases":293,"briefSummary":294,"conditions":295,"keywords":297,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":75},"100601679","adapting-an-evidence-based-intervention-to-improve-hiv-testing-and-prep-uptake-in-vietnam-100601679","NCT07113626","Adapting An Evidence-Based Intervention To Improve HIV Testing And PrEP Uptake In Vietnam","Inclusion Criteria:\n\n* Young men who have sex with men (YMSM):\n\nTheater testing. YMSM are eligible if they (1) are 18-24 years old Vietnamese male; (2) report having anal intercourse with another man in the last 6 months; (3) are HIV negative or of unknown HIV status; (4) own a smartphone; (5) currently live in Hanoi, (6) are able to read and understand Vietnamese without assistance, and (7) are willing to provide informed consent.\n\nBeta testing. Eligibility is similar to theater testing. Randomized controlled trial (RCT). YMSM are eligible if they (1) are 18-24 years old Vietnamese male; (2) report having anal intercourse with another man in the last 6 months; (3) are HIV negative or of unknown HIV status; (4) own a smartphone; (5) currently live in Hanoi, (6) are able to read and understand Vietnamese without assistance, and (7) are willing to provide informed consent and (8) are not being currently on pre-exposure prophylaxis (PrEP).\n\n* Other key stakeholders:\n\nEligibility criteria of this group are (1) having worked with MSM-related health issues at an HIV\u002FPrEP clinic or community-based organizations (CBO) for at least 6 months and (2) willingness to provide informed consent.\n\nExclusion Criteria:\n\n* Young men who have sex with men (YMSM):\n\nTheater testing. None Beta testing. Participants will be deemed ineligible if they are unwilling to provide contact information.\n\nRandomized controlled trial. Exclusion criteria include (1) unwilling to provide contact information; (2) currently enrolled in other HIV testing or PrEP program\u002Fintervention.\n\n* Other key stakeholders: None",{"count":292,"type":21},124,[24],"Young men who have sex with men are experiencing an ongoing HIV epidemic in Vietnam, with an HIV prevalence of 12%. However, HIV testing and pre-exposure prophylaxis (PrEP) use among young men who have sex with men remain low. To improve HIV testing and PrEP use, mobile health (mHealth) interventions hold great promise to reach young men who have sex with men in low- and middle-income countries. HealthMindr, an evidence-based mHealth intervention developed in the United States for men who have sex with men, is an ideal option for adaptation for young men who have sex with men in Vietnam. The specific aims are to (1) Adapt the HealthMindr app to improve HIV testing and PrEP uptake among young men who have sex with men in Vietnam; (2) Examine acceptability, feasibility and preliminary effectiveness of the adapted app among young men who have sex with men in Vietnam and (3) Explore barriers and facilitators of implementing the adapted app among young men who have sex with men in Vietnam. In Aim 1, theater testing will be conducted through focus group discussions with young men who have sex with men and key other stakeholders, including health officials, clinic staff and community-based organizations. Theater testing data will be used to refine the app for beta testing. During beta testing, a small group of young men who have sex with men will use the app for 30 days, then complete an online survey and an exit interview to rate the app's usability, provide their perspectives of the app and report any other areas for improvement. App analytics will also be collected to understand whether and how the app is used. In Aim 2, the adapted app with be tested among young men who have sex with men through a randomized controlled design. Young men who have sex with men will be randomized into the intervention or control arm (1:1 ratio). The intervention arm will have full access to the app for 3 months, while the control group will receive standard-of-care HIV services. Key app features include HIV test planning, risk and PrEP eligibility assessment, ordering of free condoms and HIV test kits, information about PrEP, and PrEP provider and HIV testing locations. HIV testing and PrEP use will be assessed at baseline and 3 months and compared between groups. A mixed methods approach will be used to evaluate app acceptability and feasibility. Quantitative data on acceptability and feasibility will be collected through the 3-month online survey, while qualitative data will be collected through in-depth interviews with a subset of young men who have sex with men in the intervention arm and other key stakeholders. In Aim 3, through the same qualitative study as Aim 2, factors that influence the implementation of the app will be explored. Determinants from seven domains will be identified: condition, technology, value proposition, adopter system, health organization, wider system and embedding\u002Fadaption over time. Only when mHealth interventions are both effective and adopted can they maximize their potential to reduce HIV incidence among target populations. This proposal will generate data for designing a full-scale hybrid type 1 effectiveness-implementation trial to test the adapted app and identify implementation strategies to address the barriers of app implementation in low and middle-income countries.",[30,296],"Control Condition",[298,299,300,301,302,303],"young men who have sex with men","HIV\u002FAIDS","HIV testing","PrEP","mHealth","Vietnam","2025-08-17",{"date":306,"type":35},"2025-08-22",{"date":308,"type":35},"2025-01-15",{"date":310,"type":21},"2029-08-31",{"name":312,"class":41},"Hanoi Medical University",{"id":314,"slug":315,"hasResults":11,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":320,"enrollmentInfo":321,"targetDuration":4,"studyType":22,"phases":323,"briefSummary":324,"conditions":325,"keywords":327,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":337,"locationsCount":75},"100598335","evaluating-the-efficacy-of-a-text-messaging-based-shisha-smoking-cessation-intervention-100598335","NCT07070154","Evaluating the Efficacy of a Text Messaging-based Shisha Smoking Cessation Intervention","Evaluating the Efficacy of a Text Messaging-based Shisha Smoking Cessation Intervention for Young Adults in Hong Kong: A Randomised Controlled Pilot Trial","Inclusion Criteria:\n\n* young adults aged 18 to 35 years who are interested in quitting shisha\n* smoked shisha within the 30 days at the time of enrolment (current smoker)\n* smoked for more than twelve times in 12 months (i.e., on a monthly basis)22\n* able to read and communicate in Chinese or English\n* agree to utilise his\u002Fher own personal mobile or smartphone to send and receive messages\n\nExclusion Criteria:\n\n* scored 10 (''have already quitted'') on Contemplation Ladder assessment at baseline\n* unable to provide consent\n* unable to read and communicate in Chinese or English","35 Years",{"count":322,"type":21},100,[24],"The goal of this study is to evaluate the efficacy of a culture specific text-messaging based shisha smoking cessation intervention for young adults in Hong Kong. Participants in the intervention group will receive smartphone text messaging-based intervention and support that contained personalised messages with both text and visual elements over 6 weeks under a manualised programme. Participants in the control group will only receive a leaflet about the health risks of shisha smoking (the exact identical contents received by the participants in the intervention group at a session).\n\nAll participants will complete a self-administered questionnaire at baseline, 6th- and 12th-week on their self-reported shisha abstinences, knowledge on risk, readiness to quit and attitudes on shisha smoking",[30,326],"Control",[328,329,330,302],"shisha smoking","text-messaging based","cessation intervention","2025-07-14",{"date":333,"type":35},"2025-07-17",{"date":335,"type":21},"2025-07-20",{"date":227,"type":21},{"name":338,"class":41},"The University of Hong Kong",{"id":340,"slug":341,"hasResults":11,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":4,"eligibilityCriteria":345,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":22,"phases":348,"briefSummary":349,"conditions":350,"keywords":351,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":362,"lastUpdatePostDateStruct":363,"startDateStruct":365,"completionDateStruct":367,"leadSponsor":369,"locationsCount":4},"100590286","effectiveness-of-ai-chatbots-in-improving-students-general-wellbeing-100590286","NCT06965439","Effectiveness of AI Chatbots in Improving Students' General Wellbeing","Evaluating the Effectiveness of AI Chatbots in Improving Students' General Wellbeing","Inclusion Criteria:\n\nCurrent undergraduate student at the National University of Singapore (NUS)\n\nAged 21 years and above\n\nProficient in English\n\nNot currently undergoing psychological treatment or taking psychiatric medication\n\nNo history of self-harm or suicide\n\nScores below 10 on both the GAD-7 and PHQ-9 (i.e., subclinical levels of anxiety and depression)\n\nExclusion Criteria:\n\nCurrently undergoing psychological treatment or counselling\n\nCurrently taking psychiatric medication\n\nHistory of self-harm or suicidal ideation\n\nScores ≥10 on the GAD-7 and\u002For PHQ-9, indicating moderate to severe anxiety or depression\n\nInability to provide informed consent or comply with study procedures",{"count":347,"type":21},172,[24],"The goal of this randomised controlled trial is to evaluate the effectiveness of an AI mental health chatbot in promoting emotional wellbeing and perceived empathy among university students in Singapore with mild or subclinical symptoms of anxiety and depression. The main questions it aims to answer are:\n\nCan the chatbot provide emotional validation and be perceived as empathic?\n\nDoes the chatbot reduce symptoms of anxiety and depression and improve wellbeing more than an inactive control condition?\n\nResearchers will compare students who engage in four sessions with the chatbot to students who complete four neutral writing tasks to assess differences in emotional wellbeing, empathy, and resilience.\n\nParticipants will:\n\nComplete baseline wellbeing assessments\n\nBe randomised to:\n\nFour 20-minute chatbot sessions providing personalised support using cognitive-behavioural and compassion-focused techniques (intervention group), or\n\nFour 20-minute neutral writing sessions unrelated to mental health (control group)\n\nComplete post-session and follow-up wellbeing questionnaires\n\nAll sessions are conducted virtually over Zoom. Participants are full-time students at the National University of Singapore, aged 21 and above. The study aims to inform future development of AI tools for emotional support in non-clinical settings.",[296,30],[352,353,354,355,356,357,358,359,360,361],"Writing task","Mental health chatbot","Digital mental health","Emotional wellbeing","Subclinical anxiety","Subclinical depression","University students","AI intervention","Cognitive behavioural therapy (CBT)","Resilience","2025-05-01",{"date":364,"type":35},"2025-05-11",{"date":366,"type":21},"2025-08-01",{"date":368,"type":21},"2025-10-31",{"name":370,"class":41},"National University of Singapore",{"id":372,"slug":373,"hasResults":11,"nctId":374,"briefTitle":375,"officialTitle":376,"acronym":4,"eligibilityCriteria":377,"healthyVolunteers":16,"sex":17,"minAge":378,"maxAge":4,"enrollmentInfo":379,"targetDuration":4,"studyType":22,"phases":381,"briefSummary":382,"conditions":383,"keywords":385,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":390,"lastUpdatePostDateStruct":391,"startDateStruct":393,"completionDateStruct":394,"leadSponsor":395,"locationsCount":4},"100581600","qigong-and-executive-attention-in-older-adults-with-depressive-symptoms-100581600","NCT06852417","Qigong and Executive Attention in Older Adults with Depressive Symptoms","Health Qigong Alleviates Depressive Symptoms in Older Adults Through Enhanced Executive Attention: a Randomized Controlled Trial","Inclusion Criteria:\n\n* have mild or severer levels of depressive symptoms, as indicated by Geriatric Depression Scale scores of 5 or above or Depression Anxiety and Stress Scale-21 depression subscale scores of 4 or above\n* self-identified as physically stable and without life-threatening diseases\n* be able to communicate in Cantonese or Mandarin.\n\nExclusion Criteria:\n\n* (have a history of practicing or receiving training in any form of mind-body or regular exercises (including tai chi, yoga, and qigong or regular physical activity \\> 3 times\u002Fweek) during the month prior to recruitment\n* have changed medications or the dose of medications prescribed for their health condition in the month prior to study enrollment\n* have a severe cognitive or language impairment, as indicated by a score of less than 21 on the Montreal Cognitive Assessment\n* receiving pharmacological treatment, electroconvulsive therapy, psychotherapy, or psychoeducation for any psychological or psychiatric condition upon the time of recruitment\n* be unable to demonstrate satisfactory standing balance.","60 Years",{"count":380,"type":21},200,[24],"The goal of this randomized controlled trial is to test whether executive attention unpacks the antidepressant effect of Baduanjin (a form of health qigong) in older adults.\n\nThe main questions it aims to answer are:\n\n* Is Baduanjin an effective treatment to enhance executive attention in older adults with depressive symptoms?\n* Does Baduanjin work through enhanced executive attention to alleviate depressive symptoms in older adults? Researchers will compare Baduanjin with waitlist control. Participants will receive 12-week Baduanjin training (two sessions per week and 60 min per session).",[30,384],"Waitlist Control",[386,387,388,389],"Health qigong","Baduanjin","executive attention","depressive symptoms","2025-02-27",{"date":392,"type":35},"2025-03-03",{"date":198,"type":21},{"date":152,"type":21},{"name":396,"class":41},"The Hong Kong Polytechnic University",{"id":398,"slug":399,"hasResults":11,"nctId":400,"briefTitle":401,"officialTitle":402,"acronym":403,"eligibilityCriteria":404,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":405,"targetDuration":4,"studyType":22,"phases":407,"briefSummary":408,"conditions":409,"keywords":411,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":416,"completionDateStruct":418,"leadSponsor":420,"locationsCount":75},"100466630","ignite-study-of-the-jewish-family-and-childrens-service-of-the-suncoast-inc-100466630","NCT05356234","Ignite Study of the Jewish Family and Children's Service of the Suncoast, Inc.","Randomized Controlled Trial of the Jewish Family and Children's Service of the Suncoast, Inc.","Ignite","Inclusion Criteria:\n\n1. Adults age 18 or older\n2. Have a child or children under the age of 24\n3. Interested in improving the parent-child relationship, sustain healthy marriages and relationships, and economic stability and employment objectives\n4. Resides in Sarasota, Manatee, and Charlotte counties on the Gulf Coast of Florida\n\nExclusion Criteria:\n\n1. Under age 18\n2. Does not reside in Sarasota, Manatee, and Charlotte counties on the Gulf Coast of Florida",{"count":406,"type":21},675,[24],"The goals of the program are to help struggling fathers and father figures improve the parent-child relationship, sustain healthy marriages and relationships (and help those who are single identify ways to enter into safe and supportive relationships that may ultimately lead to marriage), and identify and support fathers in their economic stability and employment objectives. These outcomes will be achieved through a series of workshops addressing responsible parenting and marriage and relationships as well as a complement of employment services and comprehensive case management. Additional services needed by participants will be identified and provided either through wraparound programming provided by JFCS or through collaborative agreements with local partner agencies. Additionally, Ignite will incorporate a comprehensive employment program combining both job and career advancement.",[30,410],"Wait-List Control",[412,413],"Healthy parent and child relationships","Economic self-sufficiency","2025-02-25",{"date":390,"type":35},{"date":417,"type":35},"2022-04-01",{"date":419,"type":21},"2025-06-01",{"name":421,"class":41},"Jewish Family & Children's Service of the Suncoast, Inc.",{"id":423,"slug":424,"hasResults":11,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":428,"eligibilityCriteria":429,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":430,"targetDuration":4,"studyType":22,"phases":432,"briefSummary":433,"conditions":434,"keywords":436,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":438,"startDateStruct":439,"completionDateStruct":441,"leadSponsor":442,"locationsCount":75},"100462244","restoring-empowerment-and-choosing-hope-reach-100462244","NCT05299138","Restoring Empowerment and Choosing Hope (REACH)","Restoring Empowerment and Choosing Hope (REACH) in Sarasota Florida","REACH","Inclusion Criteria:\n\n* adults age 18 or older\n* interested in education about strengthening their current marriage or committed relationship\n* reside in Sarasota, Manatee, and Charlotte counties on the Gulf Coast of Florida\n\nExclusion Criteria:\n\n* under age 18\n* do not reside in Sarasota, Manatee, and Charlotte counties",{"count":431,"type":21},900,[24],"The goals of REACH are to help adults develop the skills they need to develop healthy relationship and marriage skills, improve ability to parent and co-parent effectively, identify and enhance skills and abilities required to gain or retain economic self-sufficiency, and foster family stability and increase successful marriage rates. Data from the tri-county region comprised of Sarasota, Manatee, and Charlotte counties demonstrates the presence of a number of risk factors affecting family stability, including high rates of single-parent households, births to unwed mothers, and high median rent costs compared to poverty rates and income. By providing families with relationship enhancement, parenting, and economic self-sufficiency services, this should help to optimize each family member's quality of life and improve child well-being.",[30,435],"Wait List Control",[437],"Healthy relationships, economic self-sufficiency",{"date":390,"type":35},{"date":440,"type":35},"2022-02-17",{"date":419,"type":21},{"name":421,"class":41},{"id":444,"slug":445,"hasResults":11,"nctId":446,"briefTitle":447,"officialTitle":448,"acronym":4,"eligibilityCriteria":449,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":450,"targetDuration":4,"studyType":22,"phases":451,"briefSummary":452,"conditions":453,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":456,"lastUpdatePostDateStruct":457,"startDateStruct":459,"completionDateStruct":461,"leadSponsor":462,"locationsCount":4},"100576944","nurture-and-play---a-pilot-study-100576944","NCT06791876","'Nurture and Play' - a Pilot Study","'Nurture and Play' - a Randomized Controlled Pilot Study of a Perinatal Intervention to Strengthen Parenting Among Women with Psychosocial Vulnerabilities and Their Partners.","Inclusion Criteria:\n\n* Known with a current or previous history of anxiety and\u002For depression\n* Referred for labour at Slagelse Hospital\n\nExclusion Criteria:\n\n* Age under 18 years old\n* A need for an interpreter\n* Expecting more than one child\n* Known with schizophrenia or other serious mental illness\n* Expecting a child with a known illness\n* A history of alcohol or drug abuse",{"count":5,"type":21},[24],"The aim of this randomised controlled pilot study is to evaluate the feasibility of the Nurture and Play (NnP) offered to a Danish population of psychosocial vulnerable pregnant women and their partners.\n\nMore specifically the objectives of the study are to:\n\n* Test the feasibility of the NnP including both parents\n* Evaluate the recruitment procedure, the adherence as well as the participant's and professional´s experience of the intervention\n* Evaluate the collaboration between the hospitals and the municipalities.\n\nThe study consists of:\n\n1. A randomized controlled pilot study (n=20 women\u002Fcouples) carried out according to the Standard Protocol Items: Recommendations for Interventional Trials SPIRIT statement for clinical trials. The parents who agree to participate in the study will be randomly assigned in a 1:1 ratio to either the intervention or the control group. In addition to care-as-usual, the intervention group will be offered to participate in the NnP adapted to include partners. The intervention consists of 11 group sessions (4 perinatal and 7 postnatal sessions) and will be provided to the parents in the intervention group from around 26 weeks gestation until the baby is around seven months old. Each group session will be led by a midwife and a health nurse and will consist of four to five mothers\u002Fcouples.\n2. A qualitative descriptive interview study aiming to evaluate the participants' and professionals´ experience of the intervention.\n\nData will be collected through:\n\n* Online Questionnaires.\n* Interviews.\n* Videotaped settings.",[454,30,455],"Depression, Anxiety","Randomized Controlled Study","2025-01-24",{"date":458,"type":35},"2025-01-28",{"date":460,"type":21},"2025-02-15",{"date":255,"type":21},{"name":463,"class":464},"Center for Clinical Research and Prevention","NETWORK",{"id":466,"slug":467,"hasResults":11,"nctId":468,"briefTitle":469,"officialTitle":470,"acronym":471,"eligibilityCriteria":472,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":473,"targetDuration":4,"studyType":22,"phases":475,"briefSummary":476,"conditions":477,"keywords":479,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":487,"completionDateStruct":489,"leadSponsor":491,"locationsCount":75},"100575099","internet-delivered-therapy-for-social-anxiety-in-adults-100575099","NCT06767878","Internet Delivered Therapy for Social Anxiety in Adults","Internet Delivered Therapy for Social Anxiety in Adults (PORTiSOFIE): Study Protocol for a Randomized Controlled Trial","PORTiSOFIE","Inclusion Criteria for participants:\n\n* Scores on the screening questionnaires indicating at least moderate levels of social anxiety.\n* Age 18 years or over\n* Fluency in Portuguese\n* Access to a device with internet\n* Be in a monogamous amorous relationship (regardless of sexual orientation)\n* Not be receiving any ongoing treatment for social anxiety (e.g., stable antidepressants).\n\nInclusion Criteria for partners:\n\n* Age 18 years or over\n* Fluency in Portuguese\n* Access to a device with internet.\n\nExclusion Criteria:\n\n* Self-reported severe psychiatric disorders such as psychosis or personality disorder.\n* Planned or ongoing medical treatments (e.g., surgery) and other personal circumstances that will interfere with the treatment (e.g., planned travel abroad).",{"count":474,"type":21},62,[24],"The goal of this clinical trial is to learn if an internet-delivered CBT protocol for social anxiety in adults (PORTiSOFIE) is effective in Portugal. It will also learn about the impact that PORTiSOFIE may have on relationship dimensions of these individuals. The main questions it aims to answer are:\n\nDoes PORTiSOFIE is effective? What impact PORTiSOFIE has in relationship dimensions?\n\nParticipants will:\n\nBe assigned to experimental group and receive intervention briefly after screening is complete; Or control group and only receive intervention after the experimental group finishes.",[478,30],"Control Group",[480,481,482,483],"Social Anxiety","internet delivered CBT","Relationship satisfaction","Sexual satisfaction","2025-01-05",{"date":486,"type":35},"2025-01-10",{"date":488,"type":21},"2026-01",{"date":490,"type":21},"2027-06",{"name":492,"class":41},"Grupo Lusófona",{"id":494,"slug":495,"hasResults":11,"nctId":496,"briefTitle":497,"officialTitle":498,"acronym":4,"eligibilityCriteria":499,"healthyVolunteers":11,"sex":17,"minAge":500,"maxAge":266,"enrollmentInfo":501,"targetDuration":4,"studyType":22,"phases":503,"briefSummary":504,"conditions":505,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":509,"completionDateStruct":511,"leadSponsor":513,"locationsCount":4},"100555223","effect-of-calcium-hypochlorite-versus-sodium-hypochlorite-as-root-canal-irrigants-on-postoperative-pain-and-bacterial-reduction-in-mandibular-premolars-with-necrotic-pulps--100555223","NCT06509295","Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .","Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. A Randomized Clinical Trial.","Inclusion Criteria:\n\n1. Systematically healthy patient (ASA I, II).\n2. Age between 20 and 55 years\n3. Male or female.\n4. Mandibular premolar teeth having single canals diagnosed with pulp necrosis with asymptomatic apical periodontitis.\n5. Radiographic examination using Digora intraoral periapical sensor plate and software showing mandibular premolars with (0-2 mm) periapical radiolucency.\n\nExclusion Criteria:\n\n1. Medically compromised patients having significant systemic disorders. (ASA III or IV).\n2. History of intolerance to NSAIDS.\n3. Teeth with:\n\n   * Immature roots\n   * Vital pulp tissues.\n   * Association with swelling.\n   * Acute peri-apical abscess or acute exacerbation of a chronic abscess.\n   * Mobility Grade II or III.\n   * Previously accessed or endodontically treated\n   * Deep periodontal pockets more than 4 mm\n   * Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.\n4. Patients who could not interpret the NRS.\n5. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women were, also, excluded.","20 Years",{"count":502,"type":21},30,[24],"This study aims to assess the effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.",[30],"2024-07-13",{"date":508,"type":35},"2024-07-19",{"date":510,"type":21},"2024-08-29",{"date":512,"type":21},"2025-05-29",{"name":514,"class":41},"Cairo University",{"id":516,"slug":517,"hasResults":11,"nctId":518,"briefTitle":519,"officialTitle":519,"acronym":4,"eligibilityCriteria":520,"healthyVolunteers":16,"sex":17,"minAge":521,"maxAge":378,"enrollmentInfo":522,"targetDuration":4,"studyType":22,"phases":524,"briefSummary":526,"conditions":527,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":528,"lastUpdatePostDateStruct":529,"startDateStruct":531,"completionDateStruct":533,"leadSponsor":535,"locationsCount":75},"100551029","phase-3-to-evaluate-the-impact-of-consumption-of-bioactive-compounds-extracted-from-hemp-hull-and-black-pepper-on-fasting-blood-glucose-levels-in-people-with-pre-diabetes-a-randomized-placebo-controlled-parallel-arm-trial-100551029","NCT06454773","To Evaluate the Impact of Consumption of Bioactive Compounds Extracted From Hemp Hull and Black Pepper on Fasting Blood Glucose Levels in People With Pre-diabetes: A Randomized Placebo-Controlled Parallel Arm Trial","Inclusion Criteria:\n\n* Prediabetic individuals of BMI range 25-30 kg\u002Fm2 and waist circumference ≥80cm for women and ≥90cm for men with Fasting Blood Glucose between 100-125 mg\u002FdL.\n\nExclusion Criteria:\n\n* Prediabetic individuals of BMI range 25-30 kg\u002Fm2 and waist circumference ≥80cm for women and ≥90cm for men with Fasting Blood Glucose between 100-125 mg\u002FdL.\n\nExclusion criteria\n\n1. Weight loss or gain ≥4.5 kg within 90 days of visit 1.\n2. Use of weight loss medications within 90 days of visit 1\n3. History of gastrointestinal surgery (e.g., bariatric surgery) or cosmetic procedures (e.g., liposuction) for weight\u002Ffat reducing purposes.\n4. Use of dietary supplements or related products that, in the judgment of the Investigator, are likely to markedly affect weight loss or appetite within 30 days of visit 1.\n5. History of extreme dietary habits (e.g., Atkins diet, etc.), as judged by the Investigator.\n6. History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or binge eating) diagnosed by a health professional.\n7. Current medical diagnosis of type 1 or type 2 diabetes mellitus.\n8. HbA1c ≥48 mmol\u002Fmol (6.5%) as measured at visit 1.\n9. History of a chronic gastrointestinal disorder, such as peptic ulcer disease or malabsorption syndrome (mild lactose intolerance or gastroesophageal reflux diseases are acceptable).\n10. Signs or symptoms of an active infection of clinical relevance within 5 days of visit 1. The visit may be rescheduled such that all signs and symptoms have resolved (at the discretion of the Clinical Investigator) at least 5 days prior to visit 1.\n11. Is pregnant, planning to be pregnant during the study period, lactating, or is of childbearing potential and is unwilling to commit to the use of a medically approved form of contraception throughout the study period. The method of contraception must be recorded in the source document.\n12. Any condition the Investigator believes would interfere with his or her ability to provide informed consent, comply with the study protocol, or which might confound the interpretation of the study results or put the person at undue risk.\n13. Excessive alcohol consumption (\\> 2 Drinks, 60 ml of Whisky Per Day).","25 Years",{"count":523,"type":21},130,[525],"PHASE3","This is randomized controlled parallel arm study on free living Asian Indians. Eligible subjects will undergo one-week run-in period and subjects will be asked to maintain their usual diet and exercise regime. At the end of the run-in period, subjects fulfilling the inclusion\u002Fexclusion criteria at this stage will be randomized either to the intervention arm or control arm using computerized random number tables.\n\nThe measured parameters will include, 24-h diet recall, food frequency questionnaire, anthropometry including circumferences, height and weight, and blood parameters including blood glucose (fasting), serum insulin (fasting), HbA1c and lipid profile.",[30],"2024-06-06",{"date":530,"type":35},"2024-06-12",{"date":532,"type":35},"2024-06-01",{"date":534,"type":21},"2024-12-31",{"name":536,"class":41},"Diabetes Foundation, India"]