[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intestinal-polyps\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intestinal-polyps":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,58,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100617125","recurrence-after-gastric-and-intestinal-polyp-resection-100617125",false,"NCT07314554","Recurrence After Gastric and Intestinal Polyp Resection","Recurrence Rate and Risk Factors After Endoscopic Resection of Gastric and Intestinal Polyps: A Retrospective and Prospective Cohort Study","RAGIP","Inclusion Criteria:\n\n* Age 18 years or older\n* First-time endoscopic examination (gastroscopy or colonoscopy) at the study center\n* Pathologically confirmed polyp of any type (adenomatous, hyperplastic, inflammatory, fundic gland polyp, hamartomatous, serrated lesion)\n* Complete endoscopic resection performed (including EMR, ESD, snare polypectomy, hot biopsy forceps, or argon plasma coagulation)\n* Negative resection margins or complete resection assessed by pathology\n* At least one follow-up endoscopic examination completed (for retrospective cohort) or willingness to complete follow-up (for prospective cohort)\n* Complete baseline clinical data available\n\nExclusion Criteria:\n\n* Hereditary polyposis syndromes (familial adenomatous polyposis, Lynch syndrome, Peutz-Jeghers syndrome, juvenile polyposis syndrome)\n* Inflammatory bowel disease (ulcerative colitis or Crohn's disease)\n* Previous history of gastric or colorectal cancer\n* Cancer detected at initial resection (stage T1b or higher)\n* Non-polyp pathology (e.g., submucosal tumors, normal mucosa)\n* Incomplete resection with positive margins that were not re-treated\n* Lost to follow-up with no available surveillance data (for retrospective cohort)\n* Pregnancy at time of enrollment\n* Inability or unwillingness to provide informed consent (for prospective cohort)","ALL","18 Years",{"count":20,"type":21},2000,"ESTIMATED","3 Years","OBSERVATIONAL","This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.\n\nBACKGROUND: Gastric and intestinal polyps are common digestive diseases with potential for malignant transformation. Although endoscopic resection is the standard treatment, recurrence rates range from 10-50%, and the mechanisms and risk factors remain unclear.\n\nOBJECTIVES:\n\nPrimary: To assess short-term (1-year) and long-term (3-year) recurrence rates after endoscopic polyp resection Secondary: To identify independent risk factors and develop a recurrence risk prediction model\n\nDESIGN: Mixed retrospective-prospective cohort study\n\n* Retrospective cohort: Patients who underwent polyp resection from 2021-2022, with follow-up data through 2024\n* Prospective cohort: Patients enrolled from 2024-2025, with standardized follow-up through 2028\n\nSETTING: Single tertiary referral center with \\>10,000 endoscopic polyp resections performed since 2021\n\nPARTICIPANTS: Approximately 1,600-1,800 adult patients (≥18 years) who underwent complete endoscopic resection of gastric or intestinal polyps\n\nFOLLOW-UP:\n\n* Short-term: 1 year post-resection (±2 months)\n* Long-term: 3 years post-resection (±3 months)\n\nMAIN OUTCOME: Recurrence rate defined as new polyp detection at original or different sites during endoscopic surveillance\n\nPOTENTIAL RISK FACTORS: Patient demographics, polyp characteristics (size, number, location, pathology), resection method, Helicobacter pylori status, lifestyle factors, and medication use\n\nEXPECTED IMPACT: Results will inform personalized surveillance strategies and optimize resource allocation for post-polypectomy follow-up.",[26,27,28,29,30,31,32],"Gastric Polyps","Intestinal Polyps","Colon Polyps","Colorectal Polyps","Adenomatous Polyps","Gastric Adenoma and Early Gastric Cancer","Colorectal Adenoma",[34,35,36,37,38,39,40,41,42,43,44],"Polyp recurrence","Endoscopic resection","Polypectomy","Endoscopic mucosal resection","Endoscopic submucosal dissection","Risk factors","Surveillance","Follow-up","Adenoma","Gastric polyp","Colorectal polyp","NOT_YET_RECRUITING","2026-06-07",{"date":48,"type":49},"2026-06-09","ACTUAL",{"date":51,"type":21},"2026-07-26",{"date":53,"type":21},"2029-02-25",{"name":55,"class":56},"LanZhou University","OTHER",1,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":66,"targetDuration":4,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100615935","efficacy-of-cad-in-screening-colonoscopy-to-reduce-the-risk-of-advanced-adenoma-at-3-years-100615935","NCT07299071","Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.","Randomized Controlled Trial Evaluating the Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.","IA-COLO 2","Inclusion Criteria:\n\n* Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and\u002For for personal or family history of colorectal cancer and\u002For personal history of colonic adenomas,\n* Written informed consent signed\n* Patients covered by a health-care insurance.\n\nExclusion Criteria:\n\n* Failed complete colonoscopy, defined by the absence of cecal intubation and\u002For the absence of terminal ileum cauterization\n* Inadequate bowel preparation (Boston bowel preparation score \\\u003C 6, and\u002For least at one part of colon with score ≤ 1)\n* An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed).\n* Patient under guardianship or protection\n* Pregnant women\n* Not fluent in French or illiterate\n* Personal history of inflammatory bowel disease\n* Personal history of genetic predisposition of CRC\n* Personal history of colonic surgery",{"count":67,"type":21},592,"INTERVENTIONAL",[70],"NA","The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.",[73,74,27],"Colonoscopy","Colorectal Neoplasms",[76,77,78],"colonoscopy","colorectal neoplasms","computer aided diagnosis","RECRUITING","2026-03-13",{"date":82,"type":49},"2026-03-16",{"date":80,"type":49},{"date":85,"type":21},"2031-03",{"name":87,"class":56},"University Hospital, Bordeaux",13,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":68,"phases":99,"briefSummary":100,"conditions":101,"keywords":102,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":57},"100615300","effect-of-non-invasive-neuromodulation-on-the-quality-of-intestinal-cleansing-100615300","NCT07290816","Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing","Effect of Non-invasive Neuromodulation on the Quality of Bowel Cleansing: a Randomized, Controlled, Double-blind Clinical Study","Inclusion Criteria:\n\n* 18 to 78 years of age, male or female;\n* Intended to undergo diagnostic, screening, or surveillance colonoscopy;\n* Signed written informed consent.\n\nExclusion Criteria:\n\n* Severe cardiac, cerebral, pulmonary, or renal complications or a history of acute cardiac infarction within six months;\n* High risk factors for bowel preparation such as history of colon surgery, BMI ≥ 28, inflammatory bowel disease, constipation (less than 3 bowel movements in the last week, and with straining to defecate, with hard stools and small amount of stools) or bowel obstruction;\n* High suspicion of colorectal cancer by auxiliary examination or early warning signs and symptoms of colorectal cancer: blood in stool, black stool, unexplained anemia, significant weight loss, abdominal mass and positive rectal fingerprinting;\n* The presence of surgical incisions or scars in the area where the electrostimulation treatment tablets are pasted, or near the ST36 acupoints on both legs;\n* Are participating in other clinical observation trials or have participated in other clinical trials within 30 days.","78 Years",{"count":98,"type":21},270,[70],"To clarify whether non-invasive neuromodulation for assisted bowel preparation can improve the quality of bowel preparation, to explore the possible mechanisms by which TEA improves the quality of bowel preparation, and to assess its safety, as well as subjects' tolerance, compliance and satisfaction.",[27],[103,104],"Bowel Preparation","Noninvasive electrical neuromodulation","2025-12-17",{"date":107,"type":49},"2025-12-18",{"date":109,"type":21},"2025-12-31",{"date":111,"type":21},"2028-03-21",{"name":113,"class":56},"Shanghai East Hospital"]