[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intrathecal-dexmedetomidine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intrathecal-dexmedetomidine":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,67],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100633134","intrathecal-dexmedetomidine-with-bupivacaine-in-patients-undergoing-knee-orthopedic-surgery-100633134",false,"NCT07522736","Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery","The Analgesic Effect of Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery: A Randomized Double-Blinded Dose-Finding Trial","Inclusion Criteria:\n\n* Age from 18 to 65 years.\n* American Society of Anesthesiologists (ASA) physical status I-II.\n* Male patients scheduled for knee orthopedic surgery.\n\nExclusion Criteria:\n\n* Patients with psychiatric disorders.\n* History of drug addiction.\n* Contraindication for regional anesthesia.\n* History of hypersensitivity to the study drugs.\n* Previous administration of opioids and\u002For other central nervous system depressants during current hospital admission.","ALL","18 Years","65 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the duration of analgesia (as the primary outcome) and adverse effects (as the secondary outcome) after intrathecal administration of dexmedetomidine with hyperbaric bupivacaine to patients undergoing knee orthopedic surgery.",[27,28,29],"Intrathecal Dexmedetomidine","Bupivacaine","Knee Orthopedic Surgery","RECRUITING","2026-04-04",{"date":33,"type":34},"2026-04-13","ACTUAL",{"date":36,"type":34},"2025-03-01",{"date":38,"type":21},"2026-08-30",{"name":40,"class":41},"Cairo University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":50,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":63,"leadSponsor":65,"locationsCount":42},"100606032","transversalis-fascia-plane-block-versus-intrathecal-dexmedetomidine-in-patients-undergoing-cesarean-section-100606032","NCT07170267","Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section","Analgesic Efficacy of Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 40 years.\n* American Society of Anesthesiology (ASA) physical status II.\n* Women undergoing cesarean section under spinal anesthesia.\n\nExclusion Criteria:\n\n* Contraindication to spinal anesthesia.\n* Women with body mass index \\>40 kg\u002Fm2.\n* Pregnancy-induced hypertension\n* Local infection at the site of injection.\n* Known cardiovascular disease\n* Coagulation abnormality.\n* History of chronic pain.\n* Abuse of drugs or alcohol.\n* History of allergies to any study medications.\n* Seizure disorders.\n* Any pregnancy complications requiring conversion to general anesthesia.","FEMALE","40 Years",{"count":53,"type":21},50,[24],"This study aims to compare the analgesic efficacy of the transversalis fascia plane (TFP) block and intrathecal dexmedetomidine in patients undergoing cesarean section (CS).",[57,27,58],"Transversalis Fascia Plane Block","Cesarean Section","2025-09-13",{"date":61,"type":34},"2025-09-16",{"date":59,"type":34},{"date":64,"type":21},"2026-03-01",{"name":66,"class":41},"Tanta University",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":42},"100580480","combined-intrathecal-dexmedetomidine-and-adductor-canal-block-for-analgesia-after-total-knee-arthroplasty-100580480","NCT06837844","Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty","Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 75 years.\n* Both sexes.\n* American Society of Anesthesiology (ASA) physical status I-II.\n* Scheduled for total knee arthroplasty under spinal anesthesia.\n\nExclusion Criteria:\n\n* Patients with neurological or intellectual disability.\n* History of allergy to local anesthetics or dexmedetomidine .\n* Infection at the injection site.\n* Prolonged use of analgesic or sedative medications.\n* Coagulation abnormalities.\n* Pregnancy.\n* Obesity \\[body mass index (BMI) \\> 30 kg\u002Fm2\\].","75 Years",{"count":76,"type":21},75,[24],"The aim of this work is to evaluate the effect of combined intrathecal dexmedetomidine and adductor canal block for analgesia after total knee arthroplasty (TKA).",[27,80,81,82],"Adductor Canal Block","Analgesia","Total Knee Arthroplasty","2025-02-20",{"date":85,"type":34},"2025-02-21",{"date":83,"type":34},{"date":88,"type":21},"2025-08-01",{"name":90,"class":41},"Kafrelsheikh University"]