[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intravenous-lidocaine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intravenous-lidocaine":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100641552","phase-3-intravenous-lidocaine-to-prevent-post-fundal-pressure-headache-during-cesarean-section-100641552",false,"NCT07661758","Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section","Pre-emptive Single Intravenous Lidocaine Dose to Prevent Post-Fundal Pressure Headache During Cesarean Section: The LID-HEAD Multi-center Randomized Controlled Trial","LID-HEAD","Inclusion Criteria:\n\n* Aged ≥ 18 years\n* American Society of Anesthesiologists (ASA) Physical Status II\n* Scheduled for elective cesarean section under spinal anesthesia\n\nExclusion Criteria:\n\n* Patients declined to participate in the trial,\n* Patients with history of any type of headache, mental illness, or cerebrovascular diseases\n* Previous epidural insertion for painless labor or any other indications;\n* Patients on opioid or analgesic medications;\n* Those with pregnancy-induced hypertension or diabetic patients,\n* Allergy to lidocaine;\n* Contraindication or failure of spinal anesthesia.","FEMALE","18 Years",{"count":20,"type":21},680,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.",[27,28,29],"Intravenous Lidocaine","Fundal Pressure","Headache","NOT_YET_RECRUITING","2026-06-16",{"date":33,"type":34},"2026-06-22","ACTUAL",{"date":36,"type":21},"2026-07-01",{"date":38,"type":21},"2026-11-02",{"name":40,"class":41},"Tanta University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":42},"100624828","phase-3-intravenous-lidocaine-plus-port-site-ropivacaine-for-recovery-after-laparoscopic-surgery-100624828","NCT07414706","Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery","Evaluation of Postoperative Recovery When Combining Intravenous Lidocaine With Ropivacaine Infiltrations in Colorectal Laparoscopic Surgery","LivQor","Inclusion Criteria:\n\n* Patient undergoing scheduled colorectal cancer surgery via laparoscopy.\n* Patient aged 18 years or older.\n* Informed consent obtained and signed.\n* Affiliation to a social security system.\n\nExclusion Criteria:\n\n* Allergy or contraindication to lidocaine or ropivacaine.\n* Allergy or contraindication to paracetamol, nefopam ketamine, propofol, dexamethasone, sufentanil, Celebrex or parecoxib, morphine derivatives, and colorectal surgery by laparotomy\n* Colorectal surgery with a non-cancerous indication.\n* Chronic preoperative pain (defined as persistent pain for more than 3 months).\n* Preoperative use of opioids or opioid derivatives.\n* Patients with psychiatric disorders.\n* Patients for whom self-assessment of pain using a self-reported scale cannot be performed (non-communicative, non-French speaking, etc.).\n* Pregnant or breastfeeding women.\n* Patients under guardianship, curatorship, or legal protection.","ALL",{"count":53,"type":21},182,[24],"This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery. Participants will be assigned 1:1 to receive either intravenous lidocaine during surgery plus ropivacaine infiltration at surgical closure, or ropivacaine infiltration alone. The primary endpoint is postoperative quality of recovery measured by the QoR-15 questionnaire. Secondary endpoints include postoperative pain and opioid consumption, as well as plasma lidocaine and ropivacaine concentrations to assess systemic exposure and safety.",[27,57,58,59],"Laparoscopic Surgery","Post Operative Recovery","Local Anaesthetic Systemic Toxicity",[61,62,63,64],"Intravenous lidocaine","laparoscopic surgery","post operative recovery","local anaesthetic systemic toxicity","2026-02-12",{"date":67,"type":34},"2026-02-17",{"date":69,"type":21},"2026-03",{"date":71,"type":21},"2028-09",{"name":73,"class":41},"Centre Hospitalier Universitaire, Amiens"]