[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"intubation-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:intubation-complication":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,51,76,107,135,159,189,215,241,265,291,321,347,368,408,437,463,483,509,536],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100524838","phase-4-prevention-of-infection-of-the-respiratory-tract-through-application-of-non-invasive-methods-of-secretion-suctioning-100524838",false,"NCT06113939","Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning","Prevention of Infection of the Respiratory Tract by Applying Methods That Are Non-Invasive for Extraction of Secretions. An Open Label, Randomized, Assessor-blinded, Pilot Trial.","PIRAMIDES","Inclusion criteria\n\n1. Endotracheal intubation with an anticipated duration \\> 48 hours.\n2. High risk of early respiratory infection associated with a diagnosis of:\n\n   1. Severe trauma.\n   2. Severe traumatic brain injury.\n   3. Ischaemic or haemorrhagic stroke.\n   4. Other causes of impaired consciousness: post-resuscitated cardiac arrest status, intoxications, acute infections or diseases of the central nervous system, seizures.\n3. Informed consent signed by the patient or, when impossible due to clinical status, by their legal representative, with re-consent by the patients themselves upon regaining capacity (section 15).\n\nExclusion criteria\n\n1. Intubation with an anticipated duration \\\u003C 48 hours.\n2. Foreseeable ominous prognosis within \\\u003C 7 days.\n3. Already established indication for systemic antibiotic therapy, either for suspected aspiration pneumonia with radiological pulmonary infiltrate or for suspected non-respiratory source infection.\n4. Active haemoptysis or pulmonary haemorrhage.\n5. Unstable chest.\n6. Undrained pneumothorax (inclusion may be considered once drained).\n7. Known allergy or intolerance to beta-lactam antibiotics.","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Adults who are unconscious or severely ill and need a breathing tube connected to a ventilator are at high risk of developing a lung infection (pneumonia) within the first few days in the intensive care unit. This early pneumonia affects up to 30 to 50 % of certain high-risk patients, prolongs the time on the ventilator and in hospital, and increases the use of antibiotics.\n\nTwo strategies are commonly used today to try to prevent this infection: a short, three-day course of an intravenous antibiotic, and removal of secretions from the airway with a sterile suction catheter. Both have limitations - antibiotics can favour the growth of resistant bacteria, and catheter suctioning is uncomfortable and may injure the airway.\n\nPIRÁMIDES is a small (60-patient) pilot study that compares the current practice with two non-invasive, mechanical alternatives for keeping the airway clear: a continuous low-pressure suction system built into a special breathing tube, and a device that produces a gentle, programmed \"artificial cough\" through the ventilator. Adult patients who are intubated for severe trauma, severe brain injury, stroke, resuscitated cardiac arrest or other causes of decreased consciousness are randomly assigned, in equal numbers, to one of the three approaches and followed for 14 days, with a final visit at day 90.\n\nThe main goal is to find out which of the three strategies best prevents early pneumonia, and which provides the best overall result for patients when survival, severity of infection, need for additional antibiotics and side effects are considered together. To make these comparisons as fair as possible in an open-label study, an independent committee of doctors not involved in patient care reviews each suspected pneumonia case without knowing which strategy the patient received. The results will help design a larger trial to confirm which approach is safest and most effective for preventing early pneumonia in critically ill patients on a ventilator.",[27,28,29,30,31,32,33],"Intubation Complication","Stroke, Ischemic","Stroke Hemorrhagic","Head Trauma","Cardiac Arrest","Ventilator Associated Pneumonia","Airway Clearance Impairment",[35,36,37],"ventilator-associated pneumonia","prevention","airway clearance","NOT_YET_RECRUITING","2026-06-25",{"date":41,"type":42},"2026-06-29","ACTUAL",{"date":44,"type":21},"2026-09-15",{"date":46,"type":21},"2029-06-30",{"name":48,"class":49},"Hospital San Carlos, Madrid","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":50},"100557078","clinical-and-economic-comparison-of-2-methods-of-intubation-tube-fixation--anchorfasttm-versus-current-cord-fixation-100557078","NCT06533436","Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation : AnchorFastTM Versus Current Cord Fixation","Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation in the Intensive Care Unit: Benefits of Intubation Tube Fixation With AnchorFastTM Versus Current Cord Fixation","AnchorDon","Inclusion Criteria:\n\n* Patient over 18 years old,\n* Patient with orotracheal intubation,\n* Patient intubated no more than 24 hours previously,\n* Oral consent from patient, trusted support person or relative if unable to consent\n* Membership of a French health insurance scheme.\n\nExclusion Criteria:\n\n* Pre-existing facial, labial or auricular skin lesions,\n* Pre-existing mucositis,\n* Patients extubated for more than 24 hours whose condition requires a new intubation tube\n* Nasotracheal intubation,\n* Planned early tracheotomy,\n* Patient with occipital craniectomy,\n* Patient in ventral position,\n* Pregnant or breast-feeding woman,\n* Patient deprived of liberty or under guardianship.",{"count":60,"type":21},350,[62],"NA","The aim of this study is to assess the benefits of using the Anchorfast device in reducing complications associated with intubation tube fixation, in terms of the rate of pressure ulcer development, the rate of intubation tube mobilization and the rate of VAP occurrence. If the hypothesis is confirmed, this project would enable the caregivers to optimize the current practice in the interests of both patients and caregivers. That's why the investigators have designed a real-life study, and will also be looking at the effect of care load on and caregiver satisfaction.",[27,65],"Eschar","RECRUITING","2026-06-09",{"date":69,"type":42},"2026-06-11",{"date":71,"type":42},"2024-08-02",{"date":73,"type":21},"2027-03-01",{"name":75,"class":49},"Hopital Foch",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":83,"enrollmentInfo":84,"targetDuration":86,"studyType":87,"phases":4,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100501048","cricket-critical-events-in-anaesthetised-kids-undergoing-tracheal-intubation-100501048","NCT05804188","CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation","CRICKET","Inclusion Criteria:\n\n* All paediatric patients requiring tracheal intubation, performed by the anaesthesia team for procedures or interventions requiring general anaesthesia\n* Patients from 0 - 16 years of age.\n* Informed or general consent given, according to the relevant ethics committee statement.\n\nExclusion Criteria:\n\n* Refusal to give consent or withdrawal of consent if such is required by the relevant ethics committee.\n* Patients \\>16 years","16 Years",{"count":85,"type":21},105000,"30 Days","OBSERVATIONAL","The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites. Furthermore, the study will investigate the used intubation techniques and identify possible improvement measures to increase patient safety.",[27,90],"Adverse Events",[92,93,94,95,96],"Intubation, Intratracheal","Anesthesiology","Difficult Airway","Critical events","Pediatrics","2026-05-09",{"date":99,"type":42},"2026-05-12",{"date":101,"type":42},"2024-01-08",{"date":103,"type":21},"2026-07",{"name":105,"class":49},"Thomas Riva",8,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":116,"conditions":117,"keywords":123,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":50},"100610009","induction-agent-choice-with-early-mortality-and-prognostic-outcomes-in-critically-ill-patients-100610009","NCT07222007","Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients","Association of Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients: A Large-Scale Retrospective Cohort Analysis","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Admission to the surgical ICU for critical care\n* Administration of one of the studied induction agents\n* Availability of complete clinical data\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Absence of documented induction agent administration\n* Incomplete or missing medical records",{"count":115,"type":21},4,"The aim of this retrospective cohort study is to compare the safety and efficacy of induction agents for tracheal intubation in critically ill adult patients.",[118,27,119,120,121,122],"Critically Ill","Oxygenation","Airway Management","Propofol","Ketamine",[124],"intubation, critically ill patients, airway management","2026-04-11",{"date":127,"type":42},"2026-04-14",{"date":129,"type":21},"2026-04-18",{"date":131,"type":21},"2026-07-01",{"name":133,"class":134},"Zeliha Alicikus","OTHER_GOV",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":142,"sex":17,"minAge":18,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":146,"conditions":147,"keywords":148,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":50},"100514835","pocus-assessment-for-tracheal-vs-oesophageal-intubation-100514835","NCT05983666","POCUS ASSESSMENT FOR TRACHEAL VS OESOPHAGEAL INTUBATION","PATO","Inclusion Criteria:\n\nPatients (male or female) ASA I-III, aged between 18 and 90 years, undergoing scheduled and\u002For emergency surgery requiring orotracheal intubation. Informed consent form must be signed authorising inclusion in the study.\n\nExclusion Criteria:\n\nA.- Cervical tumours, goitre or patients who have required cervical radiotherapy.\n\nB.- Abnormalities leading to alterations of the anatomy such as facial\u002Fcervical fractures.\n\nC.- Those who cannot give their consent.",true,"90 Years",{"count":145,"type":21},200,"The clinical importance of airway management has gained prominence in the last decade in most scientific societies with the aim of improving the standard of care.\n\nThe WHO has focused guidelines for \"Safety in Surgery\", which attempt to encompass all methods that predict and recognise airway management risk and should be applied by the surgical team, and has therefore created and implemented a surgical checklist that can be useful in reducing the risk of unidentified difficulties.\n\nThe same suggestion has been included in the Helsinki Declaration on Patient Safety in Anaesthesiology, signed by most European entities in cooperation with the European Society of Anaesthesiology (ESA), the European Board of Anaesthesiology (EBA-UEMS), and the World Federation of Societies of Anaesthesiology (WFA).\n\nConfirmation of correct endotracheal tube (ET) placement is a crucial step in airway management, as unrecognised oesophageal intubation can have catastrophic consequences. Numerous methods are used to verify correct ET placement, including visual confirmation of tube passage through the vocal cords during laryngoscopy, chest wall expansion during ventilation, visualisation of the tracheal rings and carina using a flexible bronchoscope, auscultation, capnometry, capnography and chest radiography. These techniques vary in their degree of precision. Although capnography is considered the gold standard for confirming tracheal intubation, it has some important limitations.\n\nIn recent years, ultrasonography has been introduced as the fifth pillar of the physical examination of the patient: inspection, palpation, percussion, auscultation and insonation. For airway assessment and management, Point-of-Care UltraSound (PoCUS) has been incorporated into routine clinical practice, answering open diagnostic questions, aiding in differential diagnosis and guiding procedures.\n\nThus, investigators propose a simple, quick and easy-to-learn approach for the interpretation of ultrasound imaging findings during airway management.",[27],[149,150],"Tracheal intubation","Ultrasound","2026-04-09",{"date":127,"type":42},{"date":154,"type":42},"2023-07-01",{"date":156,"type":21},"2026-08-01",{"name":158,"class":49},"Clinica Universidad de Navarra, Universidad de Navarra",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":165,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":22,"phases":169,"briefSummary":170,"conditions":171,"keywords":175,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":115},"100480304","the-ed-awareness-2-trial-100480304","NCT05534243","The ED-AWARENESS-2 Trial","Awareness With Paralysis and Post-Traumatic Stress Disorder Among Mechanically Ventilated Emergency Department Survivors: the ED-AWARENESS-2 Trial","ED-AWARENES II","Inclusion Criteria:\n\n1. Mechanical ventilation via an endotracheal tube\n2. Age ≥ 18 years\n3. Treatment with a neuromuscular blocker (for endotracheal intubation or during the post-intubation phase of care)\n\nExclusion Criteria:\n\n1. Acute or chronic neurologic injury with deficit that prevents assessment of AWP (i.e. stroke, intracranial hemorrhage, traumatic brain injury, cardiac arrest, severe dementia)\n2. Death before extubation\n3. Transfer to another hospital from the ED",{"count":168,"type":21},3090,[62],"The investigators will screen all mechanically ventilated ED patients for study eligibility and will enroll all consecutive patients satisfying inclusion and exclusion criteria.\n\nThe study design is a pragmatic, multicenter, stepped wedge cluster randomized trial, enrolling at five sites over a 3-year period, divided into six time periods of six months. Prior to the study, each site will be randomized to their position within the design. One site will cross to the intervention period (i.e. succinylcholine as default neuromuscular blocker) every six months from the 2nd to 6th time period. Cluster order will be determined by computer-based randomization. To begin, each site will be exposed to control conditions; by the end of the study, each site will be exposed to intervention conditions.\n\nPatients in the control phase will receive usual care, and this phase will be entirely observational. After six months, a site will enter a 2-month transition phase. In this phase, the investigators will implement the intervention, similar to how they have implemented other ED-based interventions for mechanically ventilated patients. The investigators will engage and educate ED clinicians on the importance of AWP prevention and the study objectives. The intervention framework relies on the use of \"nudges\", without restricting choice. The use of neuromuscular blockers (i.e. \"paralytic\" medications) is already part of routine care in the ED in order to facilitate endotracheal intubation and initiation of mechanical ventilation for patients with acute respiratory failure. The two most common neuromuscular blockers used in the ED are succinylcholine and rocuronium. The preliminary data show a strong association between rocuronium (a longer-acting neuromuscular blocker) use and AWP. Therefore, this study aims to improve care by educating caregivers on AWP and the use of the neuromuscular blockers, which are already routinely used, and studying that process in a rigorous fashion. The default neuromuscular blocker in the intervention phase will be succinylcholine. Succinylcholine will be the default over rocuronium because: 1) it has safely been the default neuromuscular blocker of choice in the ED for \\>40 years ; 2) its 5-minute duration of action greatly reduces AWP risk; 3) the preliminary data regarding an increased risk of AWP with rocuronium and 4) ED rocuronium use has increased despite no patient-centered studies showing benefit over succinylcholine. Passive alerts (i.e. graphics, pocket cards) will also be strategically placed in the ED, and active alerts will be used as reminders before every nursing shift (i.e. \"the huddle\"). After this transition phase, the site will begin the intervention phase, and patients will again receive clinician-directed care, just after the intervention.",[172,173,27,174],"Awareness","Mechanical Ventilation","PTSD",[172,176,177,178,173,179],"Paralysis","Emergancy Department","Rocuronium","Intubation","2026-03-09",{"date":182,"type":42},"2026-03-12",{"date":184,"type":42},"2023-06-28",{"date":186,"type":21},"2027-09-01",{"name":188,"class":49},"Washington University School of Medicine",{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":203,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":106},"100503702","optimizing-tracheal-intubation-outcomes-and-neonatal-safety-100503702","NCT05838690","Optimizing Tracheal Intubation Outcomes and Neonatal Safety","OPTION SAFE","Inclusion Criteria:\n\nInfants undergoing tracheal intubation in the neonatal intensive care unit (NICU)\n\nExclusion Criteria:\n\nEndotracheal tube exchanges, as this represents a distinct procedure.","1 Year",{"count":198,"type":21},3000,[62],"The purpose of the study is to assess the impact of a personalized intubation planning tool, the Personalized INtubation Safety (PINS) Bundle on intubation procedural safety and clinical outcomes among patients intubated in the neonatal intensive care unit (NICU) setting.",[202,27],"Infant",[202,179,204,205],"NICU","Safety","2026-03-03",{"date":208,"type":42},"2026-03-04",{"date":210,"type":42},"2023-04-01",{"date":212,"type":21},"2027-12-31",{"name":214,"class":49},"Children's Hospital of Philadelphia",{"id":216,"slug":217,"hasResults":11,"nctId":218,"briefTitle":219,"officialTitle":220,"acronym":221,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":223,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":225,"conditions":226,"keywords":229,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":240},"100246972","improving-safety-and-quality-of-tracheal-intubation-practice-in-pediatric-icus-100246972","NCT02493478","Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs","Observation of Multi-center Quality Improvement Project: Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs","NEAR4KIDs","Inclusion Criteria:\n\n* Primary advanced airway events (on patients of all ages) in the PICU, CICU, NICU, DR and ED including: Tracheal Intubation, Laryngeal mask placement, Emergency tracheostomy and\u002For cricothyrotomy\n* Failed extubation attempts or unplanned extubations that require re-intubation will be considered a new primary intubation.\n\nExclusion Criteria:\n\n* Primary advanced airway events (tracheal intubations, laryngeal mask placement, emergency tracheostomy and\u002For cricothyrotomy) in the Operating Suites.",{"count":224,"type":21},150000,"Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.",[227,228,27],"Failed or Difficult Intubation, Sequela","Intubation; Difficult",[179,230,231],"Advanced airway intervention","Intensive care unit","2026-01-08",{"date":234,"type":42},"2026-01-09",{"date":236,"type":4},"2010-03",{"date":238,"type":21},"2030-01",{"name":214,"class":49},87,{"id":242,"slug":243,"hasResults":11,"nctId":244,"briefTitle":245,"officialTitle":245,"acronym":246,"eligibilityCriteria":247,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":248,"enrollmentInfo":249,"targetDuration":4,"studyType":22,"phases":250,"briefSummary":251,"conditions":252,"keywords":253,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":264},"100522646","smart-checklist-implementation-for-pediatric-tracheal-intubations-in-the-icu--multicenter-study-100522646","NCT06085326","Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study","SMART PICU","Inclusion Criteria:\n\nAll patients intubated in the PICU at participating sites\n\nExclusion Criteria:\n\nEndotracheal tube exchanges, as this represents a distinct procedure","19 Years",{"count":198,"type":21},[62],"The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce Adverse Airway Outcomes (AAO) across 6 diverse pediatric intensive care units (ICUs).",[27],[254,179,255,205],"Pediatric","PICU","2025-10-16",{"date":258,"type":42},"2025-10-20",{"date":260,"type":42},"2023-10-01",{"date":262,"type":21},"2028-09-30",{"name":214,"class":49},6,{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":270,"acronym":4,"eligibilityCriteria":271,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":272,"targetDuration":86,"studyType":87,"phases":4,"briefSummary":274,"conditions":275,"keywords":278,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":50},"100573796","the-impact-of-propofol-and-ketamine-on-cardiovascular-collapse-during-induction-for-intubation-100573796","NCT06750939","The Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for Intubation","The Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for Endotracheal Intubation in Critically Ill Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Patients aged over 18 years\n* Patients admitted to the intensive care unit (ICU) who undergo endotracheal intubation during their ICU stay will be included.\n\nExclusion Criteria:\n\n* Patients who did not provide consent to participate in the study\n* Patients intubated due to cardiac arrest\n* Patients intubated outside the intensive care unit",{"count":273,"type":21},128,"This prospective observational study evaluates the impact of propofol and ketamine on the risk of cardiovascular collapse during induction for endotracheal intubation in critically ill patients. Induction agents play a crucial role in managing hemodynamic stability, particularly in this vulnerable population. Propofol, known for its vasodilatory and myocardial depressant effects, has been associated with significant hypotension during induction. Conversely, ketamine, with its sympathomimetic properties, is often considered a safer alternative for hemodynamic stability.\n\nIn addition to comparing the incidence of cardiovascular collapse-defined as severe hypotension or cardiac arrest-this study examines the relationship between these induction agents and shock indices, including systolic shock index, diastolic shock index, age-adjusted shock index, and modified shock index. These parameters will provide a more detailed understanding of the hemodynamic effects of each agent and their clinical implications. The findings aim to guide induction agent selection to optimize outcomes in critically ill patients.",[276,27,277],"Cardiovascular Collapse","Anaesthetic Complication Cardiac",[279,280,281],"cardiac arrest","intubation","shock index","2025-09-16",{"date":284,"type":42},"2025-09-22",{"date":286,"type":42},"2024-07-15",{"date":288,"type":21},"2025-11-01",{"name":290,"class":134},"Kocaeli City Hospital",{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":297,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":143,"enrollmentInfo":299,"targetDuration":4,"studyType":22,"phases":301,"briefSummary":302,"conditions":303,"keywords":307,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":320},"100540889","hyperangulated-vs-macintosh-blades-for-intubation-with-videolaryngoscopy-in-icu-100540889","NCT06322719","Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU","A Randomized Comparison Between the Hyperangulated vs. Macintosh Blades for First-attempt Intubation Success With Videolaryngoscopy in ICU Patients.","INVIBLADE","Inclusion Criteria:\n\n* Age 18 years or older.\n* Admitted to an Intensive Care Unit.\n* Need for tracheal intubation during the stay in the ICU.\n* The device to be used for intubation is a videolaryngoscope\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* Emergent tracheal intubation that does not allow for the randomization of the procedure.\n* Need for tracheal intubation with a device other than the videolaryngoscope (fiberoptic bronchoscope, direct laryngoscopy, tracheostomy, etc.).\n* Tracheal intubation performed outside the ICU (Emergency Department, Hospital ward, etc.).",{"count":300,"type":21},1036,[62],"Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications. Videolaryngoscopes (VLs) devices have been proposed to improve airway management, and the use of VLs are recommended as first-line or after a first-attempt failure using direct laryngoscopy in ICU airway management algorithms. Although until relatively few years ago there were doubts about whether videolaryngoscopes had advantages over direct laryngoscopy for endotracheal intubation (ETI) in critically ill patients, two recent studies (DEVICE (1), INTUBATE (2)), and a Cochrane review (3) have confirmed that videolaryn should be used?, and what is the best blade? . There are two types of blades commonly used with videolaryngoscopes: the \"Macintosh\" blade with a slight curvature, and hyperangulated blades. The \"Macintosh\" blades have a lower angle of vision, but they have the advantage of being similar to the blades commonly used in direct laryngoscopy, making them easy to use for the person performing the ETI. Hyperangulated blades have a greater angle of vision, improving glottic visualization, especially in patients with an anterior glottis. However, the need to overcome this angulation could potentially hinder the passage of the endotracheal tube to the vocal cords. It is unknown if either blade has any advantage for intubating critically ill patients.",[304,179,305,306,27],"Acute Respiratory Failure","Intubation; Difficult or Failed","Videolaryngoscopy",[308,309,310],"videolaryngoscopy","tracheal intubation","complication","2025-09-09",{"date":313,"type":42},"2025-09-15",{"date":315,"type":42},"2024-05-01",{"date":317,"type":21},"2026-06-01",{"name":319,"class":49},"Hospital Clinico Universitario de Santiago",29,{"id":322,"slug":323,"hasResults":11,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":4,"eligibilityCriteria":327,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":328,"targetDuration":4,"studyType":22,"phases":330,"briefSummary":331,"conditions":332,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":338,"lastUpdatePostDateStruct":339,"startDateStruct":341,"completionDateStruct":343,"leadSponsor":345,"locationsCount":4},"100591597","comparing-two-methods-to-measure-nasogastric-tube-length-100591597","NCT06982495","Comparing Two Methods to Measure Nasogastric Tube Length","Comparing Two Methods for Estimating Nasogastric Tube Length: A Randomized Control Study","Inclusion Criteria:\n\n* Adults (aged ≥18 years)\n* Patients requiring nasogastric tube placement\n* Patients who are hospitalized\n\nExclusion Criteria:\n\n* Patients with a chest wound that prevents palpation of the xiphoid process\n* Patients who have had a gastrectomy\n* Patients with a gastric tumor\n* Patients with a head and neck tumor\n* Patients who are agitated and difficult to place the nasogastric tube\n* Patients with abnormal esophageal structure\n* Patients with a basilar skull fracture\n* Patients with acute upper gastrointestinal bleeding\n* Patients with an expected lifespan of less than 48 hours\n* Patients who cannot undergo an X-ray confirmation (e.g., pregnant women)\n* Patients with unstable blood pressure (mean arterial pressure \\\u003C 65 mmHg)\n* Patients with ischemic, perforated, or obstructed bowel\n* Patients with high-output fistula\u002Fostomy\n* Patients using photosensitive drugs\n* Critically ill patients\n* Patients with acute needs as determined by the attending physician\n* Patients with a Glasgow Coma Scale score \\\u003C 8",{"count":329,"type":21},220,[62],"The goal of this clinical trial is to learn if using a novel nasogastric tube assisted placement system (NCKU-NG system) can more accurately place the nasogastric tube at the optimal position in the stomach compared to conventional blind insertion techniques in adult inpatients requiring nasogastric tube placement. The main questions it aims to answer are:\n\n* Does the NCKU-NG system improve the accuracy of nasogastric tube placement at the optimal gastric position compared to standard blind insertion?\n* Does the NCKU-NG system reduce the rate of misplacement (such as entry into the airway or inadequate gastric depth), number of repeated attempts, and complication rate compared to the conventional method?\n* Can estimation of nasogastric tube length using the NCKU-NG system provide a more reliable reference than external measurement or X-ray?\n\nResearchers will compare patients randomized to nasogastric tube insertion with the NCKU-NG system (intervention arm) versus conventional blind insertion following standard external measurement methods (control arm) to see if the NCKU-NG system improves placement accuracy and reduces adverse events.\n\nParticipants will:\n\n* Be randomized to one of two groups:\n\n  * Intervention group: Receive nasogastric tube insertion using the NCKU-NG system (video-assisted real-time visualization, with active confirmation of passage through the esophagogastric junction and final position in the stomach based on sidehole location).\n  * Control group: Receive traditional nasogastric tube blind bedside insertion based on standard measurement (eg. Nose-Earlobe-Xiphoid + 10 cm).\n* All procedures will use the same material nasogastric tube (16 French polyurethane radiopaque tube).\n* Undergo confirmation of tube position by X-ray within 8 hours post-insertion for both groups.\n* Have the following outcomes assessed:\n\n  * Placement accuracy (percentage of tubes placed at optimal predefined gastric position)\n  * Number of placement attempts and failures\n  * Rate of inadvertent airway or inadequate placement\n  * Incidence of complications (e.g., aspiration, pneumothorax, gastrointestinal tract injury)\n  * Correlation between video-assisted measurement and X-ray estimation of intragastric length",[333,334,335,336,337],"Intubation, Nasogastric","Intubation Intraesophageal","Intubation Depth","Intubation Times","Intubation; Complication","2025-05-22",{"date":340,"type":42},"2025-05-29",{"date":342,"type":21},"2025-06",{"date":344,"type":21},"2025-12",{"name":346,"class":49},"National Cheng-Kung University Hospital",{"id":348,"slug":349,"hasResults":11,"nctId":350,"briefTitle":351,"officialTitle":352,"acronym":4,"eligibilityCriteria":353,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":354,"targetDuration":4,"studyType":22,"phases":356,"briefSummary":357,"conditions":358,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":359,"lastUpdatePostDateStruct":360,"startDateStruct":362,"completionDateStruct":364,"leadSponsor":366,"locationsCount":50},"100423718","diagnostic-accuracy-of-core-stethoscope-auscultation-vs-point-of-care-ultrasound-in-placement-of-endotracheal-tube-100423718","NCT04797520","Diagnostic Accuracy of Core Stethoscope Auscultation vs. Point of Care Ultrasound in Placement of Endotracheal Tube","Assessing Diagnostic Accuracy of Core Stethoscope Auscultation vs. Point of Care Ultrasound in Localizing Correct Placement of Endotracheal Tube","Inclusion Criteria:\n\n* Any patients under the age of 18\n* Surgery requiring an ETT\n* Consent\u002Fparental consent to\n\nExclusion Criteria:\n\n* Possible difficult airway\n* Significant lung pathology\n* with any major cardiac anomaly",{"count":355,"type":21},100,[62],"Misplacement of endotracheal tube (ETT) can have devastating complications for patients, some of which include respiratory failure, atelectasis, and pneumothorax.\n\nThere are a number of ways to verify the correct placement of ETT, with the stethoscope auscultation being commonly used despite its low accuracy (60-65%) in distinguishing tracheal from bronchial intubation (4-6). The gold standard techniques include Chest X Ray or fiberoptic bronchoscope (7-8), with a recent study showing point-of-care ultrasound. However, these techniques are expensive, time-consuming, often not readily available and require substantial training before users can reliably utilize them. Given intubation is often performed in urgent clinical settings, a technique that can reliably yet efficiently localize ETT would be beneficial.\n\nTele-auscultation system via Core stethoscope (Eko, Berkeley, CA) has been shown to be effective in identifying pathologic heart murmur (10) yet its potential use in guiding the correct placement of ETT has not been explored. We set out to study the suitability of Core stethoscope in detecting the correct placement of ETT.",[27],"2025-04-30",{"date":361,"type":42},"2025-05-04",{"date":363,"type":21},"2025-11",{"date":365,"type":21},"2026-11",{"name":367,"class":49},"Stanford University",{"id":369,"slug":370,"hasResults":11,"nctId":371,"briefTitle":372,"officialTitle":373,"acronym":374,"eligibilityCriteria":375,"healthyVolunteers":11,"sex":17,"minAge":376,"maxAge":377,"enrollmentInfo":378,"targetDuration":4,"studyType":22,"phases":379,"briefSummary":381,"conditions":382,"keywords":385,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":397,"lastUpdatePostDateStruct":398,"startDateStruct":400,"completionDateStruct":402,"leadSponsor":404,"locationsCount":407},"100513089","phase-3-infasurfaero-versus-sham-treatment-in-preterm-newborns-with-rds-100513089","NCT05960929","InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS","InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS: A Single-dose, Double-blind, Random Allocation, Sham-control, Clinical Trial","Aero-05","Inclusion Criteria:\n\nInclusion criteria include ALL of the following:\n\n1. Written informed consent obtained by parent or legal representative prior to or after birth\n2. Gestational age at birth ≥ 29 0\u002F7 AND ≤ 35 6\u002F7 weeks\n3. Birthweight ≥ 1,000 AND ≤ 3,500 grams\n4. Age ≥ 1 hour AND ≤ 6 hours\n5. Clinical diagnosis of surfactant-deficient RDS, with EITHER i. a Silverman-Anderson Retraction Score ≥ 5 (in Room Air), OR ii. signs of respiratory distress (tachypnea, retractions, grunting) AND radiographic confirmation\n6. Require CPAP\n7. Respiratory Severity Score (RSS) ≥ 1.25 AND ≤ 2.4\n8. If subject is \\>346\u002F7 weeks' gestation a chest radiograph is required\n\nExclusion Criteria:\n\nExclusion criteria are ANY of the following:\n\n1. Surfactant administration prior to randomization\n2. Mechanical ventilation prior to randomization\n3. Major congenital anomaly (suspected or confirmed)\n4. Abnormality of the airway (suspected or confirmed)\n5. Respiratory distress presumed secondary to an etiology other than RDS (e.g., suspected pulmonary hypoplasia, pneumothorax, meconium aspiration syndrome, pneumonia, septic or hypovolemia shock, hypoxic ischemic encephalopathy)\n6. Apgar score \\\u003C 3 at 5 minutes of age\n7. Umbilical cord gas pH \\\u003C7.0 or BD \\> 10\n8. Any condition that, in the opinion of the Investigator, would place the neonate at undue risk","29 Weeks","36 Weeks",{"count":329,"type":21},[380],"PHASE3","The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.",[383,27,384],"Respiratory Distress Syndrome (Neonatal)","Death; Neonatal",[386,387,388,389,390,391,392,393,204,394,179,395,396],"Infasurf","Calfactant","Inhalation","Nebulization","Preterm","InfasurfAero","Respiratory Distress Syndrome","Neonatal","CPAP","Aerosol","CPAP Failure","2025-03-25",{"date":399,"type":42},"2025-03-30",{"date":401,"type":42},"2025-01-01",{"date":403,"type":21},"2026-04-01",{"name":405,"class":406},"ONY","INDUSTRY",10,{"id":409,"slug":410,"hasResults":11,"nctId":411,"briefTitle":412,"officialTitle":412,"acronym":413,"eligibilityCriteria":414,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":415,"targetDuration":416,"studyType":87,"phases":4,"briefSummary":417,"conditions":418,"keywords":425,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":431,"completionDateStruct":433,"leadSponsor":435,"locationsCount":50},"100453913","register-study-implementation-of-pharyngeal-electrostimulation-therapy-for-the-treatment-of-acute-neurogenic-dysphagia-100453913","NCT05190718","Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia","R:IphEst","Inclusion Criteria:\n\n* Neurogenic dysphagia\n\n  * Ischaemic and haemorrhagic strokes\n  * Infra- as well as supra-tentorial\n  * Polyradiculitis\n  * Parkinson's disease\n  * Multiple sclerosis\n  * Dementia\n  * Traumatic brain injury\n  * Post Covid-19 pat.\n* patients over the age of 18.\n\nExclusion Criteria:\n\n* Contraindication to nasogastric tube,\n* Unstable cardiac or respiratory condition that does not allow the insertion of the Nasogastric tube\n* Pacemakers\n* Implanted defibrillators (ICD)\n* Pregnant\n* Breastfeeding women\n\n(Caution: interfering signals may be visible in ECGs, \\& EEGs with continuous recording).",{"count":355,"type":21},"90 Days","Neurogenic dysphagia occurs with disruption of neurological systems or processes involved in the execution of coordinated and safe swallowing. It is common in patients with neurological diseases, in particular in patients treated in Intensive Care Units (ICU) who are intubated (up to 62%) and \u002F or tracheotomised (up to 83%). Dysphagia is one of the most common and most dangerous symptoms of many neurological diseases. In addition, neurogenic dysphagia can have a significant impact on quality of life, medication efficacy, and malnutrition.\n\nDysphagia is currently treated conservatively on evidence-based exercises, individually adapted to each patient. In the recent years pharyngeal electrostimulation has been established and shown a positive impact on outcome. In fact, this type of therapy has not only become an addition to the existing therapy, but an important alternative for patients difficult to treat by other means.\n\nThe Phagenyx® is a medical device, which has lately been used more frequently in multiple hospitals for treatment of neurogenic dysphagia. For nearly two decades pharyngeal electrostimulation has been further developed and optimised. This therapy initiates changes in the swallowing motor cortex through neuroplasticity as well as local changes in peripheral sensory architecture associated with swallowing. Bath and colleagues (2020) recently reported the efficacy of pharyngeal electrostimulation (Phagenyx®) in various neurological conditions.\n\nAs a result, of current published studies, the use of pharyngeal electrostimulation probe, in selected patients, with neurological diseases with moderate to severe neurogenic dysphagia will be evaluated.\n\nThis trial will initially start as quality assurance project with the aim to extent it into a monocentric based register study.\n\nThe Investigators aim to validate the effectiveness of pharyngeal electrostimulation for the treatment of moderate to severe neurogenic dysphagia by systematically recording specific dysphagia-relevant parameters. At present, it is still uncertain to what extent patients with neurogenic dysphagia in the context of a non-acute neurological disease could benefit from this method.\n\nThe research questions:\n\nDoes the use of the pharyngeal electrostimulation probe have an influence on the outcome of dysphagia in patients with moderate to severe neurogenic dysphagia? How long after therapy, can the use of the pharyngeal electrostimulation probe lead to oral food intake and\u002For removal of a tracheal cannula?",[419,420,421,422,423,27,424],"Neurogenic Dysphagia","Traumatic Brain Injury","Stroke","Dysphagia","Long Covid-19","Polyradiculitis",[419,422,420,426,421,427,423],"Phagenyx","Pharyngeal electrical stimulation","2025-03-04",{"date":430,"type":42},"2025-03-07",{"date":432,"type":42},"2021-12-15",{"date":434,"type":21},"2026-12-30",{"name":436,"class":49},"Karl Landsteiner University of Health Sciences",{"id":438,"slug":439,"hasResults":11,"nctId":440,"briefTitle":441,"officialTitle":441,"acronym":442,"eligibilityCriteria":443,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":444,"targetDuration":4,"studyType":22,"phases":446,"briefSummary":447,"conditions":448,"keywords":449,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":454,"lastUpdatePostDateStruct":455,"startDateStruct":457,"completionDateStruct":459,"leadSponsor":461,"locationsCount":50},"100543781","success-rates-of-video--vs-direct-laryngoscopy-for-endotracheal-intubation-in-anesthesiology-residents-a-randomized-controlled-trial-the-juniordoc-vl-trial-100543781","NCT06360328","Success Rates of Video- vs. Direct Laryngoscopy for Endotracheal Intubation in Anesthesiology Residents: A Randomized Controlled Trial\" (The JuniorDoc-VL-Trial)","JuniorDoc-VL","Inclusion Criteria:\n\n* First Year Anesthesiology Residents\n\nExclusion Criteria:\n\n* Physicians' refusal to participate in the study\n* Participants in another study",{"count":445,"type":21},30,[62],"Securing the airway through endotracheal intubation (ETI) is a fundamental skill for anaesthetists. It is used during surgery, in the intensive care unit, during periprocedural anaesthesia and in emergency medicine. The clinical relevance of airway management is demonstrated in particular by the fact that the main cause of serious anaesthesia-related complications lies in the area of airway management. increasing technological developments in recent years (e.g. video laryngoscopy \\[VL\\]) aim to reduce the complication rate in the area of airway management. however, there are currently a large number of VLs available, which differ massively in their application. Therefore, it is essential to systematically collect data and develop structured training in airway management, taking into account current technological developments.While endotracheal intubation is traditionally performed with a direct laryngoscope, indirect video laryngoscopy, with chip-based camera technology at its tip, has been introduced across the board in recent years and is now part of standard clinical and preclinical equipment. Doctors in advanced training are trained with a focus on direct laryngoscopy; the use of and training in indirect video laryngoscopy does not follow any standards; in addition, the decision as to which method of securing the airway is chosen has so far been the responsibility of the individual doctor in anaesthesiology, although there is a tendency for the VL to be associated with a higher success rate in the first intubation attempt, the so-called \"first-pass success\".The main aim of this clinical prospective, randomised controlled trial is to train anaesthetists in advanced training in conventional direct laryngoscopy on the one hand and indirect video laryngoscopy (VL) on the other, with a focus on tracking the progress of their skills after 200 intubations with regard to first-pass success.",[27,179],[120,450,451,452,453],"Video-Laryngoscopy","First-Pass-Success","Skill of Intubation","Direct Laryngoscopy","2025-01-18",{"date":456,"type":42},"2025-01-22",{"date":458,"type":42},"2024-04-01",{"date":460,"type":21},"2027-08-01",{"name":462,"class":49},"University Hospital Heidelberg",{"id":464,"slug":465,"hasResults":11,"nctId":466,"briefTitle":467,"officialTitle":468,"acronym":4,"eligibilityCriteria":469,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":470,"targetDuration":4,"studyType":22,"phases":471,"briefSummary":472,"conditions":473,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":475,"lastUpdatePostDateStruct":476,"startDateStruct":478,"completionDateStruct":479,"leadSponsor":481,"locationsCount":4},"100568072","non-inferiority-trial-comparing-visionpro-to-glidescope-video-laryngoscopes-100568072","NCT06676462","Non-inferiority Trial Comparing visionPRO to Glidescope Video Laryngoscopes","Pilot Study Comparing the HEINE visionPRO HyMac 3 and the GlideScope Hyperangulated S3 Laryngoscope Blade on Time to Intubation","Inclusion Criteria:\n\n* Having elective surgery with general anesthesia\n* At least 18 years of age\n* requiring mechanical ventilation via an oral endotracheal tube\n\nExclusion Criteria:\n\n* More than one predictor of an anticipated difficult airway (eg, body mass index (BMI) \\>40 kg\u002Fm2, unanticipated difficult airway in the medical history (eg, Cormack \\& Lehane (C\\&L) ≥III), reduction of the atlanto-occipital joint extension \\\u003C35°, reduced thyromental distance \\\u003C6 cm or Mallampati class ≥III)\n* Age \\\u003C18 years\n* ASA class IV-VI\n* Pregnant or breastfeeding\n* Unable to provide informed written consent or under guardianship\n* Urgent surgical intervention\n* At high risk for aspiration\n* Patients undergoing any neck and throat surgery.",{"count":355,"type":21},[62],"Indirect video laryngoscope tracheal intubation with the GlideScope (Verathon Inc., Bothell, USA) has become a well-established technique in emergency and clinical anaesthesia, offering first-pass intubation success rates comparable to those achieved with direct laryngoscopy. Different video laryngoscopes vary significantly in design, including blade shape, mobility, and camera operation, which can affect patient outcomes. Two video laryngoscopes with hyperangulated blades include the GlideScope (Verathon Inc., Bothell, USA) and the visionPRO (HEINE® Optotechnick, Gilching, Germany). The Glidescope comprises an external monitor connected to a medical-grade plastic handle which is compatible with reusable and disposable blades. The newer visionPro comprises a reusable anodized aluminum integrated monitor that is attached to the camera\u002Fhandle which is compatible with disposable blades. The hyperangulated blade of the VisionPro is a unique combination of previously designed laryngoscope blades meant to increase performance. The introduction of this new hyperangulated blade design in the VisionPro raises the need to compare its performance against the established GlideScope.\n\nThe aim of this pilot study is to generate initial data to evaluate whether the use of the visionPRO (HEINE® Optotechnick, Gilching, Germany) provides a non-inferior first-pass success rate compared with the GlideScope (Verathon Inc., Bothell, USA) in surgical patients with an expected normal airway undergoing general anaesthesia The investigators hypothesize that tracheal intubation using the HEINE visionPRO will achieve a similar frequency of failed intubation and airway complications. This study plans to recruit 100 patients.",[305,27,474,120],"Video Laryngoscopy","2024-11-04",{"date":477,"type":42},"2024-11-06",{"date":401,"type":21},{"date":480,"type":21},"2027-01-01",{"name":482,"class":49},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's",{"id":484,"slug":485,"hasResults":11,"nctId":486,"briefTitle":487,"officialTitle":488,"acronym":489,"eligibilityCriteria":490,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":491,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":493,"conditions":494,"keywords":495,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":502,"completionDateStruct":504,"leadSponsor":506,"locationsCount":508},"100507227","the-danish-video-intubation-da-vition-study-100507227","NCT05884645","The DAnish VIdeo IntubaTION (DA-VITION) Study","The DAnish VIdeo IntubaTION (DA-VITION) Study: a Prospective Observational Cohort Study","DA-VITION","Patients are eligible if they adhere to all the following inclusion criteria:\n\n● Undergoing video-directed oral or nasal endotracheal intubation.\n\nExclusion criteria\n\nPatients are excluded if they adhere to one of the exclusion criteria:\n\n* Upper airway malformations (e.g., laryngomalacia, vocal cord paralysis, and subglottic stenosis).\n* Failed attempt by video laryngoscopy due to malfunctioning equipment.\n* Missing or corrupted video recording.\n* Informed consent is not obtained from the participants or participants' parents \u002F legal guardians.",{"count":492,"type":21},10000,"This study aims to train an AI for video-directed endotracheal intubation (VITION) to recognise the anatomical structures of the upper airway during video-directed endotracheal intubations.",[27,305],[496,497,498],"video-guided endotracheal intubation","artificial intelligence","videolaryngoscope","2024-09-17",{"date":501,"type":42},"2024-09-19",{"date":503,"type":42},"2023-05-01",{"date":505,"type":21},"2026-03-31",{"name":507,"class":49},"Lise Aunsholt",2,{"id":510,"slug":511,"hasResults":11,"nctId":512,"briefTitle":513,"officialTitle":514,"acronym":515,"eligibilityCriteria":516,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":517,"enrollmentInfo":518,"targetDuration":4,"studyType":22,"phases":520,"briefSummary":521,"conditions":522,"keywords":524,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":527,"lastUpdatePostDateStruct":528,"startDateStruct":530,"completionDateStruct":532,"leadSponsor":534,"locationsCount":4},"100551951","videolaryngoscopy-vs-direct-laryngoscopy-for-double-lumen-tube-lumen-tube-placement---a-multicentre-randomized-controlled-trial-volcano-study-100551951","NCT06466759","Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)","VideolaryngOscopy With Mc Grath™ vs Direct LaryngosCopy for the Positioning of A Double lumeN endOtracheal Tube (VOLCANO Study)","VOLCANO","Inclusion Criteria:\n\n* Age \\> 18 years\n* General anesthesia\n* One-lung ventilation via double-lumen tube\n\nExclusion Criteria:\n\n* Patients who refuse to consent to participation in the study.\n* Patients scheduled for awake intubation due to pre-operative evaluation findings of predictors of difficult oxygenation that contraindicate intubation under general anesthesia.\n* Patients with anatomical anomalies leading to tracheal and\u002For laryngeal displacement\u002Fcompression.\n* Patients with contraindications to double-lumen tube placement.","99 Years",{"count":519,"type":21},750,[62],"The general aim of the study is to observe whether the use of the Mc Grath™ videolaryngoscope instead of direct laryngoscopy can represent, as in the case of the single-lumen tube, an added value in the placement of the double-lumen tube for surgical procedures involving one-lung ventilation, making intubation on the first attempt more likely and quicker. Secondary objectives include evaluating the presence of an advantage of the Mc Grath™ videolaryngoscope over direct laryngoscopy for the correct placement of the double-lumen tube, the need for additional maneuvers during the intubation procedure, and the presence of intra- and post-procedural complications.",[523,27],"One Lung Ventilation",[498,525,526],"double-lumen tube","one-lung ventilation","2024-06-13",{"date":529,"type":42},"2024-06-20",{"date":531,"type":21},"2024-07-02",{"date":533,"type":21},"2026-12-31",{"name":535,"class":49},"Luca Brazzi",{"id":537,"slug":538,"hasResults":11,"nctId":539,"briefTitle":540,"officialTitle":541,"acronym":542,"eligibilityCriteria":543,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":544,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":546,"conditions":547,"keywords":548,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":552,"lastUpdatePostDateStruct":553,"startDateStruct":555,"completionDateStruct":557,"leadSponsor":558,"locationsCount":50},"100470973","neurologic-function-post-intubation-100470973","NCT05412823","Neurologic Function Post Intubation","Post Intubation Neurologic Outcomes in Critically Ill Adults","NeuroHypoxia","Inclusion Criteria:\n\n* Good baseline neurologic function (Modified Rankin Scale: 1-3)\n* Emergency departments\n* Critical care units\n* In-patient floors\n* Patients undergoing emergent intubations as determined by the treating physician\n* Age\\> 17 years old\n* Good baseline modified rankin scale (mRs 1-3)\n\nExclusion Criteria:\n\n* Pediatric patients (17 years of age of less)\n* Pregnant patients\n* Intubations occurring in the operating room\n* Prisoners\n* Trauma\n* Status epilepticus\n* Primary intracranial pathology\n* Cardiopulmonary arrest\n* Poor baseline neurologic function (Modified Rankin Scale: 4-5)\n* Pre-Hospital Intubation",{"count":545,"type":21},1000,"The frequency of oxygen desaturation during emergency intubation is not uncommon. However, the significance and clinical sequalae of hypoxia during emergency intubation in critically ill, non-trauma patients is not known. Therefore, the aim of this study is to evaluate neurologic function post-intubation of critically ill, non-trauma patients. Providing knowledge on whether the degree of hypoxia during emergency intubation is associated with worse neurologic outcomes, will guide clinical practice to ameliorate that level of hypoxia",[27],[549,550,551],"Emergency Intubation","Hypoxia","Neurologic Function","2022-08-15",{"date":554,"type":42},"2022-08-16",{"date":556,"type":42},"2022-07-22",{"date":460,"type":21},{"name":559,"class":49},"King Abdulaziz University"]