[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"iodine-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:iodine-deficiency":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100508541","phase-4-effect-of-iodine-containing-multiple-micronutrient-during-lactation-on-infant-neurodevelopment-100508541",false,"NCT05901766","Effect of Iodine-containing Multiple Micronutrient During Lactation on Infant Neurodevelopment","Effect of Maternal Supplementation With an Iodine-containing Multiple Micronutrient During Lactation on Infant Iodine Status, Thyroid Function and Neurodevelopment","To be eligible, women will be required to meet the following inclusion criteria:\n\n* Maternal age 18 years or above, singleton pregnancy,\n* data available on Last Menstrual Period (LMP) or early ultrasound,\n* Intention to exclusively feed breastmilk for 4 to 6 months,\n* Intention to stay in the study catchment area for at least 6 months,\n* Willingness to take a daily supplement of MMS for 6 months\n\nExclusion criteria include:\n\n* Severe maternal morbidity (postpartum eclampsia, postpartum hemorrhage),\n* Maternal condition leading to inability for infant to directly\u002Fexclusively breastfeed (maternal mastectomy, or other breast surgery),\n* Breast cancer,\n* Tuberculosis",true,"FEMALE","18 Years",{"count":20,"type":21},600,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.\n\nThe main questions it aims to answer are:\n\n1. What are the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers on infant development, as measured by electroencephalography\u002Fvisual evoked potentials?\n2. What are the effects of iodine-containing multiple micronutrient supplements on breast milk concentrations of iodine, and infant iodine and thyroid status?\n3. How do iodine and iron interact with each other to affect thyroid function in the mother during lactation?\n\nParticipants will be randomized to receive a daily multiple micronutrient tablet containing iodine (UNIMAPP) for 6 months postpartum, or routine postnatal care per Ethiopia Ministry of Health. Mothers will provide a breast milk sample and blood at 3 and 6 months postpartum. Infants will provide a urine sample and drop of blood, and have a neurodevelopmental assessment at 3 and 6 months.\n\nResearchers will compare the groups that received the iodine-containing micronutrient supplement with the group that received routine care and see if there were any benefits on infant development and iodine and thyroid status in the mother and baby.",[27,28,29,30],"Iodine Deficiency","Nutrition Poor","Development, Infant","Breastfeeding","NOT_YET_RECRUITING","2026-05-21",{"date":34,"type":35},"2026-05-26","ACTUAL",{"date":37,"type":21},"2026-05-01",{"date":39,"type":21},"2028-03-31",{"name":41,"class":42},"Brown University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":16,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100577699","the-next-step-towards-the-elimination-of-iodine-deficiency-and-preventable-iodine-related-disorders-in-europe-100577699","NCT06801691","The Next Step Towards the Elimination of Iodine Deficiency and Preventable Iodine-related Disorders in Europe","EUthyroid2","Inclusion Criteria:\n\n* sufficient language skills to understand the study information, informed consent\n\nExclusion Criteria:\n\n* none","ALL","13 Years","17 Years",{"count":54,"type":21},4500,[56],"NA","In the EUthyroid2 intervention, measures are being developed and implemented in educational settings across the UK, Germany, Slovenia, the Republic of Cyprus, Bangladesh, and Pakistan to effectively raise awareness of the risks associated with iodine deficiency. Each participating country will employ three measurement points. The intervention will be tailored to the specific contextual characteristics of each implementation site. A process evaluation utilizing a convergent parallel mixed methods design will be conducted, involving surveys of students and teachers, as well as semi-structured interviews.",[27],[60,27,61,62,63,64,65,66],"Prevention","Intervention Study","Complex Intervention","Adaptation to context","Awareness","Iodine intake","Nutrition education","RECRUITING","2025-02-27",{"date":70,"type":35},"2025-03-03",{"date":72,"type":35},"2024-12-30",{"date":74,"type":21},"2025-12-31",{"name":76,"class":42},"EUthyroid",6,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":47,"acronym":48,"eligibilityCriteria":83,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":108,"locationsCount":77},"100575186","euthyroid2-the-next-step-towards-the-elimination-of-iodine-deficiency-and-preventable-iodine-related-disorders-in-europe-100575186","NCT06769009","EUthyroid2: the Next Step Towards the Elimination of Iodine Deficiency and Preventable Iodine-related Disorders in Europe","Inclusion Criteria:\n\n* non-pregnant Female\n* Age 18-24 years at the time point of recruitment\n* Attending the specified settings\n* Sufficient language skills to understand the study information, informed consent and the questionnaire\n\nExclusion Criteria:\n\n* Having a thyroid disease\n* Pregnancy at the timepoint of recruitment and during the intervention period\n* Lactation","24 Years",{"count":86,"type":21},1000,[56],"In EUthyroid2 intervention measures are to be developed, implemented in ambulatory care settings and evaluated to effectively raise awareness for the risks of iodine deficiency among young women (18-24 years) in three European countries (Norway, Poland, UK) as well as Bangladesh and Pakistan. A cluster-randomized controlled trial with three points of measurements will be applied in each participating country. The intervention will be adapted to the different contextual characteristics of the implementation sites. A process evaluation with a convergent parallel mixed methods design will be conducted. For this, participants and healthcare professionals will be surveyed and semi-structured interviews will be carried out.",[27],[91,92,93,94,95,96,97,98,99,100,101],"prevention","iodine deficiency","intervention study","cluster-randomized controlled trial","complex intervention","adaption to context","awareness","urinary iodine status","iodine intake","nutrition","education","2025-02-01",{"date":104,"type":35},"2025-02-05",{"date":106,"type":35},"2024-11-18",{"date":74,"type":21},{"name":76,"class":42}]