[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"irisin\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:irisin":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100618088","the-effect-of-exercise-on-serum-irisin-levels-and-clinical-parameters-in-patients-with-axial-spondyloarthritis-100618088",false,"NCT07327073","The Effect of Exercise on Serum Irisin Levels and Clinical Parameters in Patients With Axial Spondyloarthritis.","The Effect of High-intensity Intermittent Exercise and Moderate-intensity Continuous Exercise on Serum Irisin Levels, Disease Activity, Functional Status, and Quality of Life in Patients With Axial Spondyloarthritis: a Prospective, Randomized Study","Inclusion Criteria:\n\n* Patients diagnosed with axillary spondyloarthropathy according to ASAS diagnostic criteria,\n* Having a high disease severity (ASDAS-CRP above 2.1),\n* Being sedentary (not engaging in physical activity at least 3 days a week in the last 3 months),\n* Having no change in ankylosing spondylitis medical treatment in the last 3 months,\n* Not having any orthopedic, neurological, cardiovascular, or mental disease that would affect exercise,\n* Not using any assistive devices for ambulation,\n* Having a BMI of 25 kg\u002Fm2 or less,\n* Male and female patients aged 18-50 years.\n\nExclusion Criteria:\n\n* Those with uncontrolled cardiopulmonary disease (such as hypertension, chronic obstructive pulmonary disease, heart failure),\n* Having comorbidities that reduce exercise capacity,\n* Pregnancy,\n* Malignancy,\n* Those with a recent history of surgery,\n* Those who have engaged in regular exercise (aquatic exercise, land exercise, etc.) in the previous 3 months",true,"ALL","18 Years","50 Years",{"count":21,"type":22},75,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aimed to investigate the effects of high-intensity intermittent exercise and moderate-intensity continuous exercise on serum irisin levels, disease activity, functional status, and quality of life in patients with axial spondyloarthritis.",[28,29],"Ankylosing Spondylitis (AS)","Irisin",[31,32,33],"ankylosing spondylitis","exercise","irisin","NOT_YET_RECRUITING","2026-01-09",{"date":37,"type":38},"2026-01-12","ACTUAL",{"date":40,"type":22},"2026-01-30",{"date":42,"type":22},"2026-05-30",{"name":44,"class":45},"Kirsehir Ahi Evran Universitesi","OTHER"]