[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"isothiocyanate\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:isothiocyanate":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100628404","timing-of-broccoli-sprout-intake-to-improve-exercise-performance-100628404",false,"NCT07461194","Timing of Broccoli Sprout Intake to Improve Exercise Performance","Effects of Acute and Subacute Intake of Broccoli Sprouts Intake on Exercise Performance and Recovery","Inclusion Criteria:\n\nHealthy, endurance-trained adults aged 18-64 years.\n\nRegular endurance training (e.g., cycling\u002Frunning) and ability to complete a standardized 2-hour high-intensity cycling session on an ergometer.\n\nApproved health declaration and screening assessment by study staff (including that ergometer testing can be performed safely).\n\nWilling and able to follow the study protocol (diet\u002Ffasting instructions, standardized training before visits, attendance at all four laboratory visits).\n\nNo known allergy\u002Fhypersensitivity to ingredients in the broccoli sprout drink or placebo drink.\n\nExclusion Criteria:\n\nDoes not meet inclusion criteria at screening (e.g., abnormal health declaration or medical findings making intense endurance exercise or muscle biopsy inappropriate).\n\nKnown allergy\u002Fhypersensitivity to ingredients in the intervention or placebo drink (broccoli\u002Fcruciferous vegetables or alfalfa) or other relevant food allergy.\n\nOngoing illness, fever, or infection at any test occasion, or other acute medical event judged to affect safety or data quality.\n\nOngoing treatment with medications\u002Fsupplements judged to affect primary outcomes or increase risk (e.g., anti-inflammatory medication close to test days per study instructions).\n\nPregnancy (if women are included) or breastfeeding.\n\nInability to comply with the study protocol (e.g., failure to standardize diet\u002Ffasting, deviating training\u002Falcohol intake despite instructions, or repeated missed visits).\n\nParticipant withdraws consent or investigator judges continued participation to pose risk.\n\n\\-",true,"ALL","18 Years","50 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study examines how the timing of intake of a broccoli sprout-based drink (a natural source of isothiocyanates, ITCs) affects physiological responses, recovery, and performance after a standardized endurance cycling session. Healthy, endurance-trained adults (18-64 years) will complete four laboratory visits at the Swedish School of Sport and Health Sciences (GIH): one screening\u002Fphysiology test visit and three intervention visits in a randomized, double-blind, placebo-controlled cross-over design. On intervention visits, participants will ingest either an active broccoli sprout drink (50 g sprouts) or a placebo drink based on alfalfa sprouts (50 g sprouts) according to randomization. The drink will be consumed either approximately 16 hours before exercise (the evening before) or approximately 3 hours before exercise (the morning of the test), enabling comparison of timing in relation to a standardized \\~2-hour cycling protocol (individualized intensity) followed by a 10 km cycling time trial. Outcomes include measures of performance, heart rate, perceived exertion and recovery, blood glucose and lactate, and metabolic responses. Venous blood samples are collected at multiple time points before and after exercise and during the subsequent laboratory recovery period, and muscle biopsies are obtained at defined time points to assess muscle metabolism and recovery-related markers. Participants return \\~24 hours after exercise for follow-up sampling after an overnight fast, including a glucose tolerance test",[28,29,30,31,32,33],"Physical Performance","Glucose","Glycogen Metabolism","Lactate","Broccoli Sprout","Isothiocyanate",[35,31,36,37,33],"Broccoli Sprouts","Exercise","Glycogen","NOT_YET_RECRUITING","2026-03-04",{"date":41,"type":42},"2026-03-10","ACTUAL",{"date":44,"type":22},"2026-03-31",{"date":46,"type":22},"2028-09-01",{"name":48,"class":49},"The Swedish School of Sport and Health Sciences","OTHER"]