[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"itching\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:itching":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100623380","a-new-model-to-induce-itch-and-inflammation-100623380",false,"NCT07395882","A New Model to Induce Itch and Inflammation","Investigating the Neurophysiology of Itch","Inclusion Criteria:\n\n* Healthy men and women\n* 18-60 years\n* Speak and understand English\n\nExclusion Criteria:\n\n* Pregnancy or lactation\n* Drug addiction defined as any use of cannabis, opioids, or other addictive drugs\n* Previous or current history of neurological (e.g., neuropathy), immunological (e.g., asthma, immune deficiencies, arthritis), musculoskeletal (e.g., muscular pain in the upper extremities), cardiac disorder (e.g., stroke), or psychiatric diagnoses (e.g., depression, bipolar disorders, acute and chronic psychosis) that may affect the results\n* Current use of medications that may affect the trial, such as antihistamines, antipsychotics, painkillers, and systemic or topical steroids\n* Skin diseases (e.g., atopic dermatitis, pruritus nodularis, eczema, psoriasis)\n* Moles, scars, or tattoos in the area to be treated or tested (forearm\u002Fhand).\n* Consumption of alcohol or painkillers 24 hours before the study days and between these\n* Acute or chronic pain\n* Unable to answer the \"Transcranial Magnetic Stimulation Adult Safety Screen\" (subprojects 2-4)\n* Contraindications to transcranial magnetic stimulation (TMS) application (history of epilepsy, metal implants in head or jaw, etc.) (subprojects 2-4)\n* Presence of implanted hearing aids or metal implants on the face, including permanent makeup or tattoos (subprojects 2-4)\n* Contraindications to capsaicin, including intolerance to chili or burns or wounds at the application sites (subprojects 2, 3, and 4)\n* Participation in other trials within one week of study entry (four weeks in the case of pharmaceutical trials)\n* The subject is assessed as unable to engage in the necessary cooperation required by the study",true,"ALL","18 Years","60 Years",{"count":21,"type":22},28,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project aims to create a reliable, long-lasting itch model by synergistically combining thermal pre-conditioning with the application of histamine or cowhage.",[28],"Itching","NOT_YET_RECRUITING","2026-02-09",{"date":32,"type":33},"2026-02-11","ACTUAL",{"date":35,"type":22},"2026-02-15",{"date":37,"type":22},"2029-12-31",{"name":39,"class":40},"Aalborg University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":41},"100570242","postoperative-analgesia-between-paravertebral-block-and-epidural-block-in-esophageal-surgery-100570242","NCT06704698","Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery","Paravertebral Block With Liposomal Bupivacaine and Epidural Block With Plane Bupivacaine for Postoperative Analgesia in Esophageal Surgery: A Randomized, Non-inferiority Study","Inclusion Criteria:\n\n* American Society of Anesthesiologist physical status I-III;\n* Scheduled elective thoracoscopic esophagectomy(three-incision approach);\n* Approved participation before study.\n\nExclusion Criteria:\n\n* Patients with contraindications for local nerve block such as spinal anatomic structure abnormality or local infection of puncture area;\n* Anergic to medications used in this study;\n* Patient have chronic pain;\n* Patient receiving anticoagulants, opioids or have a history of narcotic abuse or alcohol abuse;\n* Inability to complete postoperative pain assessments or questionnaires due to communication barriers or mental disorders;","80 Years",{"count":51,"type":22},132,[25],"Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients. Beneficials of epidural analgesia have been widely established. However, there are still several potential disadvantages such as perioperative hypotension, failure of administration, rare but serious neurological complications. Ultrasound-guided regional nerve block has become a widely used technique due to its low degree of trauma and precise target of action. In combined with liposome bupivacaine (LB), a new long-acting local anesthetic, was proven to have a maximum duration of 72 hours, thus improving postoperative analgesia, reducing opioid consumption, and enhancing patient satisfaction. The aim of this study was to evaluate the efficacy of TPVB liposomal bupivacaine (LB) or plane bupivacaine (SB) for Overall Benefit of Analgesic Score (OBAS) after esophageal surgery.",[55,56,57,28,58,59,60],"Pain Syndrome","Dizziness","Vomiting","Sweet Syndrome","Cold","Satisfaction, Patient","RECRUITING","2024-12-23",{"date":64,"type":33},"2024-12-30",{"date":66,"type":33},"2024-12-03",{"date":68,"type":22},"2025-12-30",{"name":70,"class":40},"Zhejiang Cancer Hospital",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":41},"100524117","comparison-of-the-effects-of-liquid-vaseline-and-olive-oil-on-itching-and-scarring-in-scald-burns-100524117","NCT06104540","Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns","Inclusion Criteria:\n\n* Between the ages of 18-65,\n* With a total body burn area of less than 15% 2nd degree scald burn,\n* Wwhose treatment has been completed and who do not need dressing and do not have open wounds,\n* Who do not have any allergies,\n* Who can read and write,\n* Who do not have cognitive problems,\n* Who do not have communication problems,\n* Who live in Ankara and who volunteer to participate in the study.\n\nExclusion Criteria:\n\n* Patients with burns on the face and neck,\n* Ppatients with dermatologic diseases and patients using antihistamines will not be included.\n* Patients who do not want to continue the study,\n* Who develop an allergic reaction during the follow-up period,\n* Who start treatment during the follow-up period due to itching,\n* Wwho have not applied more than 20% liquid vaseline\u002Folive oil during the 3-month follow-up period (60 applications\u002F30 days; more than 36 applications out of 180 applications) will be excluded from the study.","65 Years",{"count":79,"type":22},24,[25],"Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life. Liquid petroleum jelly and olive oil have no side effects, moisturizing properties, or wound-healing treatment of burns due to their positive effects on symptoms such as itching. can be used to alleviate burns. The project found the use of liquid petroleum jelly and olive oil to determine the effect on itching and scarring in burn patients. After burns reduction of symptoms such as itching, dryness, hypertrophic scarring, and patient comfort. Provision of care is a part of nursing care. In studies, itching and scarring there is insufficient evidence regarding the treatment methods applied for its treatment is observed. In addition, the effect of olive oil and liquid petroleum jelly on itching and scarring no scientific study was found. The results of the project were found to be significant in terms of post-burn itching providing evidence of hypertrophic scar management and contributing to ongoing studies is expected to be found. Since there are no similar studies in the literature, a preliminary study with 24 patient applications will be made. In line with the data obtained from the pre-application, the sample calculation will be made and the application will continue by making the necessary arrangements. Patients will be divided into experimental and control groups by simple randomization. All patient groups individual data collection forms on the first day; 12 individual data collection forms on the first day, 15th day, first, second, and third months Itemized Itch Severity Scale, Patient and Observer Scar Scale to be applied in Burn Patients and the wound area will be photographed. Patients in the control group will be given no application will be made. Liquid petroleum jelly and olive oil group before the study training will be given and they will massage the recommended product twice a day for 3 months and will be asked to record them. The data obtained at the end of the project will be statistically analyzed and results will be presented.",[83,28,84],"Scald Burn","Hypertrophic Scarring",[86,87,88,89,90,91],"scald burns","nursing care","oliveoil","liquid vaseline","itching","hypertrophic scarring","2024-07-31",{"date":94,"type":33},"2024-08-02",{"date":96,"type":22},"2024-09-01",{"date":98,"type":22},"2025-01-31",{"name":100,"class":40},"Ankara Yildirim Beyazıt University"]