[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"jaundice\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:jaundice":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,77,102,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100611628","impact-of-prepartum-intravenous-fluid-intake-on-newborn-weight-loss-in-the-first-days-of-life-100611628",false,"NCT07243054","Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life","PERLE","Inclusion Criteria:\n\n* Full-term delivery (≥37+0 SA)\n* Singleton pregnancy\n* Mother over 18 years of age\n* Infant formula feeding exclusively in the maternity ward for the first 2 days\n\nExclusion Criteria:\n\n* Mother under guardianship\n* Mother who does not understand French\n* Mother objecting to her personal data being reused for research purposes\n* Incomplete or incorrectly completed patient medical record\n* Mixed or exclusive breastfeeding\n* Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason\n* Child with renal pathology or uropathy\n* Children with cleft lip, palate or labio-palate","FEMALE","18 Years",{"count":19,"type":20},200,"ESTIMATED","OBSERVATIONAL","At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula.\n\nThis observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (\\> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn.\n\nThe investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.",[24,25,26,27,28],"Vascular Filling","Newborn","Weight Loss","Jaundice","Respiratory Distress",[30,31,32,33,34],"vascular filling","newborn","weight loss","jaundice","respiratory distress","RECRUITING","2025-11-17",{"date":38,"type":39},"2025-11-21","ACTUAL",{"date":41,"type":39},"2025-03-01",{"date":43,"type":20},"2025-11",{"name":45,"class":46},"Centre Hospitalier Universitaire, Amiens","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":17,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":47},"100529451","ssm-predicts-outcomes-of-cld-inpatients-with-acute-liver-injury-100529451","NCT06173947","SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury","Spleen Stiffness Measurement Predicts Short-term Outcomes of Chronic Liver Disease Inpatients With Acute Liver Injury: a Prospective, Observational and Multicentre Study","Inclusion Criteria:\n\n1. Age between 18 years and 80 years\n2. Chronic liver diseases regardless of etiology\n3. Acute liver injury with total bilirubin ≥ 3 mg\u002Fdl regardless of inducement\n\nExclusion Criteria:\n\n1. Prior surgery of liver diseases before enrollment such as liver transplantation, transjugular intrahepatic portosystemic shunt (TIPS), splenectomy and partial splenic embolization\n2. Severe extrahepatic diseases such as chronic obstructive pulmonary disease level IV, chronic kidney disease with end-stage renal failure, myocardial infarction within 3 months before admission\n3. Receiving Immunosuppressive drugs for reasons rather than chronic liver diseases\n4. Diagnosis of hepatocellular carcinoma or other non-liver malignancies during screening period\n5. Serious mental illnesses such as anxiety, depressive disorders to obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD)\n6. The pregnant\n7. Jaundice due to biliary obstruction or cholestasis\n8. Unsuitable to participate in this study judging by investigators","ALL","80 Years",{"count":58,"type":20},411,"In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the effect of dynamic changes in SSM on the short-term prognosis (28-day, 90-day morbidity and mortality) of inpatients with CLD and acute liver injury.",[61,27,62,63],"End Stage Liver Disease","Liver Dysfunction","Portal Hypertension",[61,65,66,67,63,27],"Chronic Liver Disease","Spleen Stiffness Measurement","Acute-on-Chronic Liver Failure","2025-05-19",{"date":70,"type":39},"2025-05-21",{"date":72,"type":39},"2024-01-01",{"date":74,"type":20},"2025-12-30",{"name":76,"class":46},"Nanfang Hospital, Southern Medical University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":55,"minAge":4,"maxAge":84,"enrollmentInfo":85,"targetDuration":87,"studyType":21,"phases":4,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":47},"100533926","value-of-transcutaneous-bilirubin-devices-100533926","NCT06232174","Value of Transcutaneous Bilirubin Devices","Study of the Value of Transcutaneous Bilirubin Devices in Jaundiced Newborns at Assiut University Children's Hospital","Inclusion Criteria:\n\n* They were born between 35 and 42 weeks of gestation, had a birth weight of more than 2 kg, and were aged between 0 days and 28 days\n\nExclusion Criteria:\n\n* Exclusion criteria are severely ill neonates, neonates with a lethal congenital malformation, and or had skin disease, had received phototherapy before, and received exchange transfusion.","28 Days",{"count":86,"type":20},80,"25 Days","The goal of this observational study is to compare the value of transcutaneous bilirubin devices versus serum bilirubin in jaundiced neonates",[27],[91],"Neonatal jaundice","NOT_YET_RECRUITING","2024-07-29",{"date":95,"type":39},"2024-07-30",{"date":97,"type":20},"2024-08",{"date":99,"type":20},"2025-03",{"name":101,"class":46},"Assiut University",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":109,"sex":55,"minAge":17,"maxAge":110,"enrollmentInfo":111,"targetDuration":113,"studyType":21,"phases":4,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":4},"100537354","the-linfu-us-registry-in-patients-with-clinical-signs-andor-symptoms-of-disease-100537354","NCT06276738","The LINFU® U.S. Registry in Patients With Clinical Signs and\u002For Symptoms of Disease","The LINFU® U.S. Registry for the Detection of Pancreatic Ductal Adenocarcinoma (PDAC) in Patients With Clinical Signs and\u002For Symptoms of Disease","Inclusion Criteria:\n\n* Both males and females will be enrolled and must be at least 18 years of age and under age of 90\n* Patients, who in the opinion of the Investigator, require biopsy to rule out PDAC because they display at least one of the following or both: a) clinical symptoms of PDAC including jaundice, nausea and vomiting, weight loss, abdominal pain, bloating or the feeling of fullness, itchy skin, lower back pain, light-colored, greasy stools, sudden onset type 2 diabetes, etc. b) one or more imaging studies suggestive of PDAC\n* All patients must undergo contemporaneous imaging, either within 90 days before the LINFU® procedure or within 30 days after the procedure, with one or more of the following: EUS± FNA, MRI\u002FMRCP, ERCP, CT or CEUS.\n* Institutional Review Board (IRB)-approved consent must be signed by patients to participate in this study.\n\nExclusion Criteria:\n\n* Patient under the age of 18 and over the age 90\n* Contraindications to LINFU®\u002FEUS\u002FERCP as determined by study investigators: Patient with uncorrectable coagulopathy; Patient that cannot undergo anesthesia due to cardiopulmonary contraindication as deemed by the anesthesiologist; Unstable medically (cardiopulmonary, neurologic, or cardiovascular status)\n* Patients undergoing EUS or ERCP for a suspected bile duct cancer arising from the intrahepatic or extrahepatic biliary epithelium\n* Patients who are already known to have PDAC by cytologic or histologic evidence\n* Patients with intraductal papillary mucinous neoplasm of the pancreas (IPMN) identified either before the study or during the study through imaging evaluation will be excluded\n* Pregnant females will be excluded\n* Patient that is unable to provide informed consent\n* Patient with known allergy to the microbubble contrast agent or secretin",true,"90 Years",{"count":112,"type":20},1000,"5 Years","Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC.",[116,27,117],"Pancreatic Cancer","Abdominal Neoplasm","2024-05-12",{"date":120,"type":39},"2024-05-14",{"date":122,"type":20},"2024-06-30",{"date":124,"type":20},"2034-05-01",{"name":126,"class":127},"Adenocyte, LLC","INDUSTRY",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":55,"minAge":136,"maxAge":137,"enrollmentInfo":138,"targetDuration":4,"studyType":140,"phases":141,"briefSummary":143,"conditions":144,"keywords":150,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":164},"100537672","physiologically-based-cord-clamping-to-improve-neonatal-outcomes-in-moderate-and-late-preterm-newborns-100537672","NCT06280872","Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns","Prospective Unblinded Randomized Controlled Study Assessing the Physiologically Based Cord Clamping on Ventilation Duration in Moderate and Late Preterm","PhyCordPrem","Inclusion Criteria:\n\nPregnant women followed-up in Brugmann University Hospital will be eligible to participate if:\n\n* The delivery takes place between 32 0\u002F7 and 36 6\u002F7 weeks of gestation\n* They carry singletons\n\nExclusion Criteria:\n\n* Fetal anomalies including congenital malformations, anemia, and growth restriction with abnormal Dopplers.\n* Abnormal placentation such as placenta previa.\n* Signs of fetal distress necessitating an emergency cesarean section.\n* Maternal health issue including severe anemia (defined as hemoglobin level \\\u003C 7 g\u002FdL), preeclampsia, and bleeding disorders.\n* Maternal refusal of the use of blood products.\n* General anesthesia for cesarian section.\n* Planned cord blood banking.\n* Total language barrier without possibility of translation","32 Weeks","36 Weeks",{"count":139,"type":20},180,"INTERVENTIONAL",[142],"NA","Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid. After vaginal delivery, the umbilical cord is clamped and cut after a delay that allows some of the blood in the umbilical cord and placenta to flow back into the baby. Meanwhile, as the baby breathes for the first time, the lungs fill with air and more fluid is pushed out. However, it does not always work out that way.\n\nA baby born prematurely may have breathing problems because of extra fluid staying in the lungs related to the immaturity of the lung structure. Thus, the baby must breathe quicker and harder to get enough oxygen enter into the lungs. The newborn is separated from the mother to provide emergency respiratory support. Although the baby is usually getting better within one or two days, the treatment requires close monitoring, breathing help, and nutritional help as the baby is too tired to suck and swallow milk. Sometimes, the baby cannot recover well and show greater trouble breathing needing intensive care. This further separates the mother and her baby. A possible mean to help the baby to adapt better after a premature birth while staying close to the mother is to delay cord clamping when efficient breathing is established, either spontaneously or after receiving breathing help at birth. In this study, we intend to test this procedure in moderate or late preterm infants and see whether the technique helps the baby to better adapt after birth and to better initiate a deep bond with the mother.",[145,146,147,148,149,27],"Premature Birth","Respiratory Distress Syndrome in Premature Infant","Sepsis","Intraventricular Hemorrhage of Prematurity","Bronchodysplasia",[151,152,153,154],"Moderate and late preterm newborn","Neonatal respiratory morbidity","Physiological based-cord clamping","Mother-infant bonding","2024-03-01",{"date":157,"type":39},"2024-03-05",{"date":159,"type":39},"2024-02-19",{"date":161,"type":20},"2026-07",{"name":163,"class":46},"Queen Fabiola Children's University Hospital",2]