[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"jaw-cysts\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:jaw-cysts":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100625598","bone-regeneration-using-prf-after-cyst-enucleation-100625598",false,"NCT07424716","Bone Regeneration Using PRF After Cyst Enucleation","Clinical Efficacy of Platelet-Rich Fibrin in Osseous Regeneration After Cystic Enucleation","PRF-Bone","Inclusion Criteria:\n\n* Patients diagnosed with odontogenic cysts requiring surgical enucleation.\n* Presence of a postoperative osseous defect in the jaws after cyst enucleation.\n* Age ≥ 18 years.\n* Systemically healthy patients (ASA I or II).\n* Patients willing to participate and sign informed consent.\n\nExclusion Criteria:\n\n* Patients with systemic diseases affecting bone healing (e.g., uncontrolled diabetes, osteoporosis).\n* Patients receiving bisphosphonates or long-term corticosteroid therapy.\n* Smokers (\\>10 cigarettes\u002Fday).\n* Pregnant or lactating women.\n* Patients with acute infection at the surgical site.\n* Patients unwilling to participate or unable to attend follow-up visits.","ALL","18 Years","80 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws. The study will assess bone healing outcomes and compare PRF application with conventional management methods.",[28,29,30],"Odontogenic Cyst","Jaw Cysts","Osseous Defect After Cyst Enucleation",[32,33,34,35,36,37,38,39],"Platelet-Rich Fibrin","PRF","Cyst Enucleation","Bone Regeneration","Randomized Controlled Trial","Oral Surgery","Osseous Healing","Jaw Bone Defect","RECRUITING","2026-02-14",{"date":43,"type":44},"2026-02-20","ACTUAL",{"date":46,"type":44},"2025-05-19",{"date":48,"type":22},"2026-10-19",{"name":50,"class":51},"Sana'a University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":17,"minAge":18,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":23,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":4},"100609163","phase-3-low-intensity-pulsed-ultrasound-as-an-adjunctive-therapy-for-bone-regeneration-following-jaw-cyst-enucleation-100609163","NCT07210983","Low-Intensity Pulsed Ultrasound as an Adjunctive Therapy for Bone Regeneration Following Jaw Cyst Enucleation","Low-Intensity Pulsed Ultrasound as an Adjunctive Therapy for Bone Regeneration Following Jaw Cyst Enucleation With Curettage: A Randomized Controlled Trial","LIPUS","Inclusion Criteria:\n\n* age ≥18 years.\n* having undergone cyst enucleation with curettage.\n* postoperative histopathological confirmation of a jaw cyst.\n* willingness to complete 10 days of standardized LIPUS therapy\n\nExclusion Criteria:\n\n* severe psychiatric disorders impairing compliance.\n* acute infection.\n* presence of a cardiac pacemaker.\n* osteoporosis.",true,"60 Years",{"count":64,"type":22},29,[66],"PHASE3","This study tested whether low-intensity pulsed ultrasound (LIPUS) could help patients recover better after surgery to remove jaw cysts.\n\nA total of 29 patients with 33 jaw cysts were included. After surgery, they were randomly assigned to two groups:\n\nUltrasound group (17 patients, 18 cysts): received daily LIPUS therapy for 10 days.\n\nControl group (12 patients, 15 cysts): received the same care but with a sham (inactive) device.\n\nThe study was triple-blinded, meaning that the patients, the surgeon, and the evaluators did not know who was receiving real or sham treatment.\n\nResearchers measured recovery in several ways:\n\nPatient reports: pain, numbness, anxiety\u002Fdepression, and oral health-related quality of life.\n\nClinician monitoring: checked for any side effects (like infection or burns). Imaging tests (CBCT scans): tracked how well bone healed by measuring changes in cyst cavity size (volume reduction) and new bone density.\n\nAll patients had the same type of surgery, performed by the same surgeon, and all provided written informed consent. The study followed international ethics and trial registration standards.",[29,69],"Curettage",[35,71,29,72,73,74],"Hounsfield unit","Low-intensity pulsed ultrasound","Three-Dimensional Volumetric Analysis","Bone Density","NOT_YET_RECRUITING","2025-09-30",{"date":78,"type":44},"2025-10-07",{"date":80,"type":22},"2025-10-22",{"date":82,"type":22},"2026-05-30",{"name":84,"class":51},"Sadam Elayah",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":61,"sex":17,"minAge":18,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":23,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":102,"leadSponsor":104,"locationsCount":52},"100559699","treatment-of-mandibular-bone-cyst-by-navigation-and-endoscopy-100559699","NCT06567535","Treatment of Mandibular Bone Cyst by Navigation and Endoscopy","A Single-arm, Single-center Clinical Study of Endoscopic Combined With Intraoperative Navigation-assisted Treatment of Giant Mandibular Cysts","Inclusion Criteria:\n\n1. They are between 18 and 75 years old\n2. Imaging and puncture pathology showed odontogenic cystic lesion of the mandible\n3. Cystic lesions greater than or equal to 2cm in diameter and spread to the inferior alveolar nerve\n4. New or recurrent cyst lesions, or odontogenic cystic lesions that are still greater than or equal to 2cm after other treatment such as fenestration and affecting the lower alveolar nerve\n5. No serious systemic disease, tolerant of general anesthesia\n6. Patients undergoing surgical treatment for mandibular bone cysts under general anesthesia\n7. There was no inferior alveolar nerve injury before operation\n8. Have not participated in other clinical trials within 30 days\n9. Patients who volunteer to participate in the program and sign informed consent\n\nExclusion Criteria:\n\n1. The patient has severe systemic disease or pregnancy, and is judged to be unable to tolerate the course of this clinical study and cannot tolerate general anesthesia after evaluation by the research team and multidisciplinary consultation\n2. Inability to complete the entire clinical research process due to personal, social, and economic reasons\n3. Patients with psychiatric disorders or inability to perceive and communicate normally, such as schizophrenia, claustrophobia, etc., are unable to complete the examination and cooperate in the entire clinical research process","75 Years",{"count":94,"type":22},122,[25],"In this study, with the assistance of endoscopic technology and intraoperative navigation technology, the removal and curettage of large odontogenic jaw cyst occurred in the mandible were performed to reduce the rate of postoperative nerve injury. In this study, the investigators compared the efficacy of traditional extraction and curettage with endoscopic navigation assistance in the treatment of giant mandibular bone cysts. In this study, the rate of inferior alveolar nerve injury 1 month after surgery was taken as the main outcome index, and the recurrence rate 1 year after surgery was taken as the secondary outcome index, to explore whether endoscopic combined with intraoperative navigation-assisted treatment of giant mandibular bone cyst could achieve lower postoperative nerve injury rate and postoperative recurrence rate.",[29],"2024-08-20",{"date":100,"type":44},"2024-08-22",{"date":98,"type":22},{"date":103,"type":22},"2026-12-30",{"name":105,"class":51},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University"]