[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"jaw-edentulous-partially\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:jaw-edentulous-partially":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,72,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100417293","two-unit-cantilever-implant-prostheses-made-of-monolithic-zirconia-or-pfm-100417293",false,"NCT04713800","Two-unit Cantilever Implant Prostheses Made of Monolithic Zirconia or PFM","Randomized Controlled Clinical Trial of Two-unit Cantilever Implant Prostheses Made of Monolithic Zirconia on Titanium Base Abutments or Porcelain-fused to Metal on Gold Abutments","Cantilever","Inclusion Criteria:\n\n* Minimal age of 22 years old.\n* No general medical condition which represents a contraindication to implant treatment\n* Good oral hygiene (PII ≤ 20%), and healthy periodontal tissues (BOP≤ 20%)\n* Two adjacent-teeth gap in posterior maxilla or mandible arch (first premolar, second premolar, first molar, second molar) with an osseointegrated regular or wide-diameter bone-level implant in a prosthetically correct position to allow occlusal screw-retention. Free-end edentulous gaps can also be included\n* Presence of antagonist occlusal units\n\nExclusion Criteria:\n\n* Severe bruxism or clenching habits\n* Patients with inadequate oral hygiene or persistent intraoral infection\n* Women who are pregnant or breast feeding at the day of inclusion\n* Smokers exceeding 15 cigarettes \u002F day, or equivalent; patients chewing tobacco\n* Unable or unwilling to cooperate for the trial period\n* Estimated cantilever crown mesial-distal length \\> 10 mm\n* Estimated implant crown height (from implant platform to occlusal contact points) \\> 15 mm",true,"ALL","22 Years",{"count":21,"type":22},38,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim of is to compare the survival rate and technical outcomes of cantilever implant-supported fixed denture prosthetics (cFDPs) made either out of monolithic zirconia bonded to a titanium base in a digital workflow, or porcelain fused-to metal using a gold abutment in a conventional workflow. In addition, biological outcomes, wear patterns, PROMs and time efficiency will be recorded. The null hypothesis is: the reconstruction type does not influence the survival rate and technical outcomes of 2-unit implant-supported cFDP.",[28,29],"Jaw, Edentulous, Partially","Missing Teeth",[31,15,32,33,34,35,36],"Dental Implants","Titanium base","Dental abutment","Fixed dental prosthesis","Monolithic zirconia","Porcelain fused to metal","RECRUITING","2022-11-21",{"date":40,"type":41},"2022-11-23","ACTUAL",{"date":43,"type":41},"2021-07-28",{"date":45,"type":22},"2027-07",{"name":47,"class":48},"University of Geneva, Switzerland","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":18,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":49},"100276637","effects-of-splinted-or-non-splinted-single-unit-crowns-on-marginal-bone-level-alterations-around-implants-100276637","NCT02880891","Effects of Splinted or Non-splinted Single-unit Crowns on Marginal Bone-level Alterations Around Implants","School and Hospital of Somatology, Peking University","Inclusion Criteria:\n\n1. All patients would be in general good health.\n2. All patients would need for fixed implant-supported prosthesis in the double posterior maxillae or mandibulae (there were at least two corresponding adjacent teeth lost in both sides from the 1st premolar to 2nd molar).\n3. The patients could be followed-up for 36 months after prosthetic loading\n4. A wide ridge of bone allowing the insertion of a 4mm platform implant and at least 8mm of bone in vertical height would be required.\n5. The same posterior teeth had lost on both sides for more than 6 months.\n\nExclusion Criteria:\n\n1. For implant site, a ridge of bone do not allow the insertion of a 4mm platform implant and at least 8mm of bone in vertical height.\n2. Current need for pre-surgical bone or soft tissue augmentation in the planned implant area;\n3. Uncontrolled pathologic processes in the oral cavity;\n4. History of radiation therapy in the head and neck region;\n5. History of chemotherapy within 5 years prior to surgery;\n6. Systemic or local disease or condition that could compromise post-operative healing and\u002For osseointegration;\n7. Uncontrolled diabetes mellitus;\n8. Corticosteroids or any other medication that could influence post-operative healing and\u002For osseointegration;\n9. Smoking more than 10 cigarettes\u002Fday;\n10. Present alcohol and\u002For drug abuse","20 Years",{"count":59,"type":22},20,[25],"The microthreaded and platform switched implants could control the stress in the suitable range. The splint would disturb the function. So it is necessary to know whether the splinted single-unit crowns is fit for the adjacent multi-implants.\n\nOutcome variables: Splinted single-unit crowns on one side implants and non-splinted single-unit crowns on the other side Materials and method: 80-100 consecutive implants in at least 20 patients would be included for implant- supported restorations in the posterior maxilla or mandibular. All patients would be in general good health. For every patient, the same posterior teeth had lost on both sides for more than 6 months. All patients were treated by the same qualified surgeon.\n\nProsthetics procedure would be performed by an experienced prosthodontist. The two sides were allocated to the test or the control group according to the predefined computer-generated randomization table. Clinical evaluations and radiographic analysis were performed by an oral and maxillofacial radiologist who was not aware of the type of Prosthetics technique that was used.",[28],"2022-04-19",{"date":65,"type":41},"2022-04-26",{"date":67,"type":4},"2016-09",{"date":69,"type":22},"2026-09",{"name":71,"class":48},"Peking University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":18,"minAge":57,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":81,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":100},"100404230","maxillary-sinus-floor-augmentation-in-diabetic-patients-100404230","NCT04543630","Maxillary Sinus Floor Augmentation in Diabetic Patients","Maxillary Sinus Floor Augmentation in Diabetic Patients With Particulated Autogenous Bone Graft Compared With Advanced Platelet-rich Fibrin. A Randomized Controlled Trial","Inclusion Criteria:\n\n* ≥20 years.\n* Insulin-dependent diabetes with missing posterior maxillary tooth\u002Fteeth.\n* Residual bone height of the maxillary alveolar process between 4 and 7 mm.\n* Width of the alveolar process ≥6.5 mm.\n* Presence of mandibular occluding teeth.\n* Plasma glucose levels below 7.8 mmol\u002Fl or 140 mg\u002Fdl.\n\nExclusion Criteria:\n\n* Contraindications to implant therapy.\n* Full mouth plaque score \\>25%.\n* Progressive periodontitis.\n* Acute infection in the area intended for implant placement.\n* Parafunction, bruxism, or clenching.\n* Psychiatric problems or unrealistic expectations.\n* Smoking. Previous smoker will not be excluded.\n* Pregnancy",{"count":80,"type":22},40,[25],"Placement of implants in diabetic patients is associated with higher risk of implant failure and peri-implant marginal bone loss due to an increased susceptibility to infections, impaired wound healing and associated microvascular complications. However, diabetic patients do not encounter a higher implant failure rate compared with non-diabetic patients, if the plasma glucose levels are normal.\n\nProsthetic rehabilitation of the posterior maxilla with implants is frequently compromised due to atrophy of the alveolar process and pneumatisation of the maxillary sinus. Maxillary sinus floor augmentation (MSFA) with autogenous bone graft is generally considered the preferred grafting material due to its osteoinductive, osteogenic, and osteoconductive properties. However, harvesting of autogenous bone graft is associated with risk of donor site morbidity and unpredictable resorption of the graft. Thus, bone substitutes, blood coagulum and platelet rich fibrin are used increasingly to simplify the surgical procedure.\n\nFabrication of advanced platelet rich fibrin (APRF) from blood samples possess significant potential for bone regeneration without the use of additional autogenous bone grafts or bone substitutes. Consequently, use of APRF in conjunction with MSFA will avoid bone harvesting and simplify the surgical procedure.\n\nThe objective is to test the H0-hypothesis of no difference in implant treatment outcome after MSFA with particulated autogenous bone graft compared with APRF. Forty consecutively insulin-dependent diabetes patients with missing posterior maxillary tooth\u002Fteeth will be allocated to implant placement and MSFA with particulated autogenous bone graft from the zygomatic buttress or APRF. Blood samples will be obtained preoperatively and postoperatively. Clinical and radiographical evaluation using periapical radiographs and CBCT will be performed preoperatively, immediate postoperatively, before abutment connection, after prosthetic rehabilitation, one year, three years and five years after loading to assess the implant treatment outcome and the volumetric changes of the augmented area. Outcome measures will include survival of suprastructures and implants, volumetric stability of the augmented area, peri-implant marginal bone level, immunological analyses of blood samples, oral health related quality of life, and complications related to the two treatment modalities.",[28,84],"Diabetes",[86,87,88,89,84],"Implant Dentistry","Sinus floor augmentation","Autogenous bone","Platelet-rich fibrin","NOT_YET_RECRUITING","2020-11-11",{"date":93,"type":41},"2020-11-13",{"date":95,"type":22},"2020-12-01",{"date":97,"type":22},"2028-12-01",{"name":99,"class":48},"University of Copenhagen",3,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":18,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":49},"100271521","esthetic-clinical-and-radiographic-outcomes-of-immediate-and-delayed-implant-placement-100271521","NCT02814149","Esthetic, Clinical and Radiographic Outcomes of Immediate and Delayed Implant Placement","Esthetic, Clinical and Radiographic Outcomes of Immediate Implant Placement and Delayed Implant Placement in the Anterior Region of the Maxilla","Inclusion Criteria:\n\n* At least 18 years old and able to understand an informed consent\n* Adequate oral hygiene to allow for implant therapy consistent with standards of care.\n* Missing a single tooth in the maxillary anterior region\n* Presence of adjacent natural teeth\n\nExclusion Criteria:\n\n* Poor oral hygiene\n* Severe parafunctional habits, for example, bruxing and clenching\n* Presence of clinically active periodontal disease as expressed by probing pocket depths≥4 mm in combination with bleeding on probing.\n* Conditions that might lead to a possibly lowered regenerative capacity of the bone, for example, osteoporosis and Paget's disease\n* Pregnant or expecting to be pregnant\n* History of drug and alcohol abuse\n* History of systemic diseases that would contraindicate oral surgical treatment, for example, uncontrolled diabetes (defined as HBA1c level \\>7%)\n* Radiotherapy in the head and neck area,\n* On certain medications like bisphosphonates or steroids currently or within the past three months\n* Absence of adjacent teeth\n* Unwillingness to return for the follow-up examination\n* Smokers (more than 20 cigarettes per day). Subjects smoking \\\u003C20 cigarettes per day were requested to stop smoking before and after surgery","18 Years","80 Years",{"count":80,"type":22},[25],"The aim of this prospective cohort study is to compare the esthetic, clinical and patient-centered outcomes following immediate and delayed implant placement protocols.",[28,114],"Acquired Absence of Single Tooth",[116,117,118,119],"delayed implant","esthetics","immediate implant","bone augmentation","2019-10-31",{"date":122,"type":41},"2019-11-01",{"date":124,"type":41},"2016-05",{"date":126,"type":22},"2027-06",{"name":128,"class":48},"Sun Yat-sen University"]