[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"jumping-gap\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:jumping-gap":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100632114","labial-bone-thickness-change-in-immediate-implant-placement-in-maxillary-esthetic-zone-100632114",false,"NCT07509476","Labial Bone Thickness Change in Immediate Implant Placement In Maxillary Esthetic Zone","Clinical and Radiographic Evaluation of Change in Labial Bone Thickness in Immediate Implant Placement In Maxillary Esthetic Zone Comparing a Jumping Gap of Less Than 2 mm to Equal or More Than 2 mm: A Non-randomized Clinical Trial","Inclusion Criteria:\n\n1. Patients with a bounded single non-restorable upper tooth in the anterior maxilla (15-25) FDI (El Ebiary et al., 2023b)\n2. Patients with an age range of 21 to 65 years old (Levine et al., 2022)\n3. Patients with good oral hygiene with BoP ≤ 10 % (Chapple et al., 2018)\n4. Compliant patients willing to follow up to one year.\n5. Remaining labial bone thickness ≥ 1mm measured on C.B.C.T. and confirmed on the day of surgery after tooth extraction and before final implant placement.\n\nExclusion Criteria:\n\n1. The presence of acute\u002Factive infection related to the non-restorable tooth (Block et al., 2009) cited in (Soegiantho et al., 2023)\n2. Presence of labial bone defect as fenestration\u002Fdehiscence (Crespi et al., 2008) cited in (Soegiantho et al., 2023)\n3. Large cyst or pathological lesion related to the tooth (Tallarico et al., 2016-2017) cited in (Soegiantho et al., 2023); (Morton, Wismeijer, Chen, Hamilton, Wittneben, Casentini, Gonzaga, Lazarin, Martin, Molinero-Mourelle, et al., 2023)\n4. History of radiation to the maxilla (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023)\n5. History of bisphosphonate therapy or other anti-resorptive agents (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023)\n6. Uncontrolled systemic or metabolic disease. (Cecchinato et al., 2015) cited in (Soegiantho et al., 2023)\n7. Patients with parafunctional habits or active periodontitis (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023) 8- Tobacco abuse (\\>10 cigarettes per day) (Canullo et al., 2010) cited in (Soegiantho et al., 2023)\n\n9- Alcohol abuse (Block et al., 2009) cited in (Soegiantho et al., 2023)","ALL","21 Years",{"count":19,"type":20},22,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to assess the effect of distance between the implant and the bone on the resultant bone thickness adjacent to the implant in place of a broken down tooth that happens to be bounded by two natural teeth.\n\nThe main questions it aims to answer are:\n\nDoes the horizontal implant position (and hence the gap between the implant and the socket wall i.e. jumping gap) affect the resultant labial bone thickness? Will it affect the quality of soft tissue, esthetics and patient satisfaction?\n\nParticipants will have an implant placed using a surgical guide with a jumping gap either less than 2 mm or equal or more than 2 mm and will be asked to visit the clinic once every 3 months for checkups, radiographs, and readings.",[26,27,28,29],"Guided Immediate Implant Placement","Jumping Gap","Labial Bone Thickness Change","Broken Down Tooth Rehabilitation",[31,32,33,34,35],"Immediate implant placement","Customized healing abutment","Jumping gap","Surgical guide","Accuracy of surgical guide","RECRUITING","2026-03-29",{"date":39,"type":40},"2026-04-03","ACTUAL",{"date":42,"type":40},"2025-06-18",{"date":44,"type":20},"2028-06-18",{"name":46,"class":47},"Cairo University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100623034","thymoquinone-around-immediate-implant-100623034","NCT07391384","Thymoquinone Around Immediate Implant","Evaluation of the Effect of Thymoquinone Hydrogel With Bone Graft in Comparison to Bone Graft Only Around Immediate Implant (Randomized Controlled Clinical Trials)","Thymoquinone","Inclusion Criteria:\n\n* 1- Patients ages more than 18 years old, Participants were chosen according to specific eligibility criteria, requiring them to be healthy individuals classified as ASA I by the American Society of Anesthesiologists.\n\n  2- Patients requiring extraction of posterior teeth with consequent immediate implant placement.\n\n  3- Indications for extraction included: non restorable teeth (posterior teeth), untreatable caries, endodontic failures, remaining roots, vertical fracture of the roots.\n\n  4- Natural teeth adjacent to the tooth to be extracted will required to have complete occlusal surfaces and be free from infections..\n\n  5\\. Patients will selected with a thick soft tissue phenotype and a minimum keratinized tissue width (KTW) of 2 mm.\n\nExclusion Criteria:\n\n* Pathologies or drugs that alter tissue integration with dental implants. 2- Head and neck radiation therapy. 3- Renal disease, bleeding disorders and anticoagulant therapy. 4- Pregnant females. 5- Patients with severe para-functional habits and unfavorable occlusion 6- Smokers. 7- Malaligned teeth and teeth with acute periapical pathosis.","20 Years","55 Years",{"count":60,"type":20},44,[23],"use of Thymoquinone hydrogel with bone graft in comparison to bone graft only around immediate implant-this hydrogel fill the jumping zone in comparison to using hydrogel bone graft only to increase primary stability and enhance osseointegration",[64,27,65],"Immediate Dental Implant Placement","Primary Stability of the Implants",[67,68,69,70],"immediate implant","thymoquinone","hydrogel","bone graft","NOT_YET_RECRUITING","2026-01-29",{"date":74,"type":40},"2026-02-05",{"date":76,"type":20},"2026-01-21",{"date":78,"type":20},"2026-04-11",{"name":80,"class":47},"shaimaa hamdy"]