[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"keratinized-tissue-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:keratinized-tissue-deficiency":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,60],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100634082","pontic-site-development-with-or-without-fixed-partial-denture-100634082",false,"NCT07535060","Pontic Site Development With or Without Fixed Partial Denture","Clinical and Volumetric Evaluation of Soft Tissue Augmentation Using Connective Tissue Graft (CTG) in Pontic Site Defects With and Without Fixed Partial Dentures. A Non-randomized Clinical Trial.","Pontic Site","Inclusion Criteria:\n\n* Patients will on missing tooth in the esthetic zone (2nd premolar to 2nd premolar), missing at least 3 months prior to recruitment, with or without FPD\n* Systemically free patient\n* ≥18 years of age\n* Intact gingival tissue with at least 2mm keratinized tissue in adjacent teeth\n* Patients accept to provide informed consent\n\nExclusion Criteria:\n\n* Smokers.\n* Pregnancy and lactation\n* Periodontitis\n* Severe gagging reflex\n* Handicapped and mentally challenged patients\n* Active soft tissue infection",true,"ALL","18 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects. It compares clinical and volumetric outcomes between sites with an existing fixed partial denture (FDP) and sites without an FDP.\n\nFollowing tooth extraction, alveolar ridge resorption often leads to soft tissue defects that can compromise esthetics, function, and prosthetic outcomes. CTG is considered the gold standard for soft tissue augmentation due to its predictable improvement in tissue thickness and stability.\n\nIn this non-randomized clinical trial, patients with single edentulous sites in the esthetic zone will undergo CTG using a standardized surgical technique. The primary outcome is keratinized tissue thickness, while secondary outcomes include keratinized tissue width, volumetric soft tissue changes, esthetic evaluation (Pink Esthetic Score), plaque index, post-operative pain, and patient satisfaction.\n\nClinical and digital assessments will be conducted preoperatively and at follow-up intervals up to 6 months. The study aims to determine whether performing CTG around an existing bridge provides comparable or improved outcomes compared to sites without a bridge, potentially offering a less invasive alternative to prosthetic replacement.",[28,29,30,31],"Mucogingival Defects","Pontic Site Development","Keratinized Tissue Deficiency","Connective Tissue Graft",[33,34,29,35,36,37,38,39,40,41,42,43,44,45,46],"Connective Tissue Graft (CTG)","Soft Tissue Augmentation","Alveolar Ridge Defects","Fixed Partial Denture (FDP)","Ridge Augmentation","Periodontal Plastic Surgery","Keratinized Tissue Thickness","Keratinized Tissue Width","Esthetic Outcome","Pink Esthetic Score (PES)","Volumetric Soft Tissue Analysis","Dental Prosthetics","Edentulous Ridge","Non-Randomized Clinical Trial","RECRUITING","2026-04-27",{"date":50,"type":51},"2026-05-01","ACTUAL",{"date":53,"type":51},"2025-10-06",{"date":55,"type":22},"2027-06-01",{"name":57,"class":58},"Cairo University","OTHER",1,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":67,"targetDuration":4,"studyType":23,"phases":69,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":59},"100624432","3d-digital-assessment-of-soft-tissue-changes-after-modified-fgg-100624432","NCT07409558","3D Digital Assessment of Soft Tissue Changes After Modified FGG","Three-Dimensional Direct Digital Evaluation of Soft Tissue Volumetric Changes After Modified Free Gingival Graft Surgery: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Age 18 years or older\n* Systemically healthy individuals\n* Non-smokers\n* Presence of localized Cairo Class II gingival recession with a vertical recession depth of ≥3 mm on the buccal surfaces of mandibular incisors\n* Probing pocket depth of ≤3 mm at the tooth\u002Fteeth to be treated\n* No tooth mobility (mobility grade ≤1)\n* Absence of cervical composite restorations or non-carious cervical lesions\n* Presence of a shallow vestibule (\\\u003C5 mm)\n\nExclusion Criteria:\n\n* Pregnancy or lactation\n* Untreated periodontal disease\n* Presence of parafunctional habits\n* Poor oral hygiene, defined as a full-mouth plaque score \\>20%\n* Malpositioned, rotated, or crowded teeth in the buccal position\n* Known systemic diseases (e.g., acquired immunodeficiency syndrome, diabetes mellitus)\n* Any condition or medication that may affect gingival wound healing\n* ASA physical status classification III or higher",{"count":68,"type":22},34,[25],"The aim of this randomized controlled clinical trial is to evaluate the effects of conventional free gingival graft (FGG) and modified free gingival graft (ModFGG) techniques on soft tissue thickness, volumetric change, and creeping attachment in mandibular incisors using three-dimensional direct digital analysis. The study will include a total of 34 systemically healthy, non-smoking individuals with localized Cairo Class II gingival recession. Participants will be randomly assigned to the FGG (control) and ModFGG (test) groups. Clinical measurements will be performed before surgery and at 1, 3, and 6 months post-surgery. Soft tissue thickness and volumetric changes will be analyzed three-dimensionally by overlaying digital models obtained with an intraoral scanner. Gingival recession depth, keratinized tissue height, and creeping attachment will also be assessed. The aim is to provide clinical evidence regarding the effects of the modified free gingival graft technique on soft tissue stability and volumetric gains.",[72,73,30],"Gingival Recession, Localized","Soft Tissue Volume Changes",[75,76,77,78],"Modified Free Gingival Graft","Free Gingival Graft","Soft Tissue Volume","Three-Dimensional Digital Analysis","2026-02-12",{"date":81,"type":51},"2026-02-13",{"date":83,"type":51},"2025-01-04",{"date":85,"type":22},"2026-07-31",{"name":87,"class":58},"Kahramanmaras Sutcu Imam University"]