[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"kidney-replacement-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:kidney-replacement-therapy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100587237","community-health-workers-in-an-interdisciplinary-outpatient-ckd-clinic-to-optimize-social-care-navigation-patient-engagement-and-home-dialysis-utilization-100587237",false,"NCT06925776","Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization","Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization- the CHOOSE Home Trial","CHOOSE Home","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Advanced CKD (defined by estimated glomerular filtration rate (eGFR) of 25 ml\u002Fmin\u002F1.73m2 or less using the 2021 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation)\n* English or Spanish speaking\n* Provide informed consent\n* Followed by a nephrologist at Montefiore and seen within last 12 months\n* Willing to receive interdisciplinary care (i.e., nurse practitioner facilitated CKD education and care coordination)\n\nExclusion Criteria:\n\n* Active malignancy\n* Anticipated survival is less than 1 year as determined by the patient's treating nephrologist\n* Opting to do medical management only (non- dialysis supportive care) for management of their kidney failure\n* Plan to relocate outside of New York City within the next 12 months","ALL","18 Years",{"count":20,"type":21},106,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if this intervention (the CHOOSE Home intervention) is feasible and may lead to more home dialysis usage in a high-risk patient population. The main questions it aims to answer are:\n\n* Will there be an increase in home dialysis selection or initiation over study follow up?\n* Will there be a change in patient reported status of Health-Related Social Needs (HRSNs) and patient engagement at 1 year follow up?\n\nResearchers will compare the intervention group that will include interdisciplinary care (IDC) and the integration of a Community Health Worker (CHW) into the chronic kidney disease (CKD) care process to the IDC only control group. The research team will assess whether the intervention led to better social care navigation, enhanced patient engagement, and increased home dialysis use.",[27],"Kidney Replacement Therapy",[29,30,27,31,32,33,34,35,36],"Community Health Worker","Interdisciplinary Care","home dialysis","Health-Related Social Needs","patent engagement","Hemodialysis","home hemodialysis","peritoneal dialysis","RECRUITING","2026-04-14",{"date":40,"type":41},"2026-04-15","ACTUAL",{"date":43,"type":41},"2025-12-12",{"date":45,"type":21},"2028-05",{"name":47,"class":48},"Montefiore Medical Center","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100626595","a-survey-for-patients-and-caregivers-aiming-to-understand-and-improve-the-care-of-patients-at-high-risk-of-transfer-from-peritoneal-dialysis-to-hemodialysis-100626595","NCT07437677","A Survey for Patients and Caregivers Aiming to Understand and Improve the Care of Patients at High Risk of Transfer From Peritoneal Dialysis to Hemodialysis:","Understand, Plan and Improve Care and Wellbeing of Patients at High Risk of Transfer From Peritoneal Dialysis to Hemodialysis - Phase 2 (Survey)","ULIFT-PD","Inclusion Criteria:\n\n1. Adult (≥18 years)\n2. One of the following:\n\n   * Patient who experienced a PD-to-HD transition in past 12 months\n   * Patient currently receiving peritoneal dialysis\n   * Caregiver (self-defined, including spouses, family members, or friends) of individuals meeting the above criteria\n3. Able to read English or French\n4. Able to complete the survey in paper or web-based format\n5. Able to provide informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Unable to provide consent",true,{"count":60,"type":21},200,"OBSERVATIONAL","Home dialysis is encouraged in Canada and peritoneal dialysis is the most common home dialysis method. However, many patients discontinue peritoneal dialysis, often transferring to hemodialysis. Despite the frequency of this transition, little is known about its impact on patients.\n\nOverall, the UPLIFT-PD program aims to fill this gap by studying the transition from peritoneal dialysis to hemodialysis. The specific goal of this mixed methods sub-study is to conduct a national survey to ask patients and caregivers about priorities and preferences when they anticipate a transfer from peritoneal dialysis to hemodialysis. This survey will be co-created by patient-partners and dialysis experts.\n\nResults from this survey will then be used in other phases of UPLIFT-PD program, detailed in other registrations, which will support people facing a transition from peritoneal dialysis to hemodialysis..",[64,34,27,65],"Peritoneal Dialysis (PD)","Transition",[67],"Transfer to hemodialysis","NOT_YET_RECRUITING","2026-02-24",{"date":71,"type":41},"2026-02-27",{"date":73,"type":21},"2027-01",{"date":75,"type":21},"2029-12",{"name":77,"class":48},"Ciusss de L'Est de l'Île de Montréal",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":89,"conditions":90,"keywords":95,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":49},"100605133","the-rhabdomyolysis-evaluation-in-the-emergency-department-reed-score-100605133","NCT07158554","The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score","The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score - a Risk Prediction Model for Older Adults in the Emergency Department With Rhabdomyolysis After Prolonged Immobilisation (\"Long Lie\")","The REED Score","Inclusion Criteria:\n\nThe participants need to fulfil all three parts of the inclusion criteria:\n\n1. 60 years old or older at time of ED presentation\n2. Developed rhabdomyolysis (defined as CK \\>999U\u002FL)\n3. Have had a fall and been \u002F suspected to have been on the floor \u002F immobilised in one position for \\> 59 minutes.\n\nExclusion Criteria:\n\n1. Patient opted out of research studies via the National Data Opt Out (NDOO) Service.\n2. Principal Investigator (PI) had clinical input into patient care.\n3. Other causes of elevated creatine kinase (e.g. seizures, acute coronary syndromes, burns, myositis, muscular dystrophy, cardiac arrest)","60 Years",{"count":88,"type":21},1000,"One in three adults over 65 fall annually, with one in five remaining on the floor for greater than one hour, which is referred to as a long lie. Pressure on the National Health Service has resulted in extended stays in the Emergency Department (ED) (sometimes longer than 12 hours) and prolonged ambulance response times. This impacts the older adults who have fallen and remain on the floor.\n\nThis project aims to develop a risk prediction model (RPM) for use within the ED to understand which older adults (60 years or older) who fall over and remain on the floor for longer than one hour (\"long lie\") and develop rhabdomyolysis (a serious condition where muscle breaks down and releases substances into the blood that can damage the kidneys) will develop poor outcomes and need admission to hospital for treatment and which patients can be safely discharged home.\n\nAim:\n\nTo develop a RPM to identify which older adults who have a fall and a long lie and attend the ED develop poor outcomes such as Acute kidney Injury (AKI) \\[kidneys suddenly stop working properly\\], needing kidney replacement therapy (KRT) \\[a treatment that helps kidneys that aren't working properly do their job of cleaning the blood\\] and mortality \\[death\\].\n\nObjectives:\n\n1. Abstract patient level data (e.g. biochemical, demographic, situational, medical history, medication history) from medical records combined with outcomes to understand which variables lead to poor outcomes such as AKI, needing KRT and mortality.\n2. Analyse the data using a statistical package (Statistical Package for Social Sciences \\[SPSS\\]) to develop a RPM with good discriminative abilities \\[how well the score can tell high-risk from low-risk patients\\].\n3. Demonstrate the ability of the RPM to identify which patients need admission to hospital with treatment and which patients can be safely discharged home.",[91,92,27,93,94],"Rhabdomyolysis","Death","Fall Patients","Acute Kidney Injury",[84,91,96,97],"Emergency Department","Long Lie","2025-09-10",{"date":100,"type":41},"2025-09-17",{"date":102,"type":21},"2025-10",{"date":104,"type":21},"2026-04",{"name":106,"class":48},"University of Salford"]