[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"kidney-replacement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:kidney-replacement":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100530107","development-and-test-of-a-communication-skills-training-for-transplant-providers---aims-2--3-100530107",false,"NCT06182475","Development and Test of a Communication Skills Training for Transplant Providers - Aims 2 & 3","Increasing Equity in Live Donor Kidney Transplantation Through Effective Patient-Provider Communication","EPPComm","Inclusion Criteria:\n\n* (1) appear for a kidney transplant evaluation at Cooperman Barnabas Medical Center (CBMC) or Temple University Hospital (TUH)\n* (2) speak English\n* (3) be of self-reported Black or Caucasian ethnicity\n* (4) be ≥18 years of age.\n\nIncluding patients who:\n\n1. have received prior kidney transplants\n2. patients with limited English proficiency, as long as they speak with the physician via a translator\n3. patients evaluated at offsite satellite locations that are not actually at CBMC or TUHS.\n\nAll transplant nephrologists, nurses, and social workers employed at the kidney transplant programs at CBMC and TUH who are actively involved in patient evaluations for transplant will be eligible for participation in the study. Providers refusing to permit digital audio recording of the transplant consultation will be deemed ineligible.\n\nExclusion Criteria:\n\n* (1) are non-verbal or otherwise unable to converse with providers\n* (2) are already listed for kidney transplant at CBMC or TUHS or at another transplant center\n* (3) have limited English proficiency and speak directly with the physician in a language other than English.\n\nPatients having (1) received an offer to donate a kidney from a family member or friend, or (2) explicitly asked a family member or friend to consider serving as a LD will be excluded, along with any patients refusing to permit digital audio recording of the transplant consultation will also be deemed ineligible to participate.\n\nThe following special populations will be excluded: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), prisoners, and individuals who do not understand English.\n\nIt is unlikely that any female patient will be pregnant while awaiting kidney transplant; however, we will not exclude pregnant women.","ALL","18 Years","80 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to understand the communication occurring between Black and Caucasian patients and their transplant providers during transplant evaluation consultations and assess relationships between these communicative elements and patient and provider factors, patient-reported outcomes and living donor transplant outcomes - living donor referrals, evaluations, and transplants. We will use these findings to inform the development of a communication skills training for transplant providers and test the impact of the training on providers' communication about live donor kidney transplants with Black and Caucasian patients and living donor transplant outcomes.\n\nThe main questions it aims to answer are:\n\n* How does the use of the use of instrumental, relational and affective communication by patients and providers during the transplant consultation differ by patient and provider factors, patient-reported outcomes and patient ethnicity?\n* What elements of instrumental, relational and affective communication will be predictive of live donor kidney transplant (LDKT) process outcomes (LD inquiries and evaluations, and actual LDKTs)?\n\nParticipants will be asked to complete brief surveys before and after the transplant consultation and to give permission for the consultation to be audiorecorded.\n\nThis data will be used to develop a training to educate providers on the key communication factors predictive of LDKT process outcomes specific to Black and Caucasian patients, and provide guidance on their application during patient consultations. Researchers will then compare communication and patient-reported and LDKT process outcomes between trained and untrained providers to see whether the training has any effect on living donor inquiries and evaluations, and actual LDKTs.",[28,29,30],"Kidney Disease, Chronic","End Stage Renal Disease","Kidney Replacement",[32,33,34,35],"Patient-Provider Communication","Live Donor Kideny Transplantation","Provider Training","Communication Skills Training","NOT_YET_RECRUITING","2026-06-10",{"date":39,"type":40},"2026-06-12","ACTUAL",{"date":42,"type":22},"2026-09",{"date":44,"type":22},"2027-05",{"name":46,"class":47},"Temple University","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100544840","kidney-perfusion-with-or-without-absorption-100544840","NCT06374121","Kidney Perfusion With or Without Absorption","A Single-center, Pilot, Prospective, Randomized Clinical Study of Hypothermic Oxygenated Perfusion With or Without Adsorption in Histologically Evaluated Kidneys Retrieved From Marginal Donors","POWER","Inclusion Criteria:\n\n* Males and females older than 50 years eligible for single or dual kidney transplant from marginal donors identified according to the NITp criteria (\\>70-year-old or 60 to 70 years with hypertension and\u002For diabetes and\u002For clinical proteinuria)\n* Pre-transplant histological evaluation\n* Histological score ≤ 7\n* Written informed consent.\n\nExclusion Criteria:\n\n* Any factor that represents a contraindication to receive a deceased donor kidney transplant according to the NITp criteria,\n* Need for specific desensitization protocols because of a high immunological risk according to the NITp criteria,\n* Active enrollment in concomitant intervention studies,\n* Macroscopic vascular abnormalities that preclude the possibility of machine perfusion.","50 Years",{"count":58,"type":22},10,[25],"In this single-center, pilot, prospective, randomized study, the investigators will compare the biochemical profiles of the perfusate and the functional parameters of five kidneys perfused with Integrated PerLife® system and \"PerSorb ECOS-300CY ™\" sorbent (adsorption groups) with the profiles of the perfusate and functional parameters of five matched kidneys perfused with Integrated PerLife® system only (non-adsorption group). Kidneys from marginal donors with a clinical indication to pre-transplant histological evaluation (donor \\>70-years-old or aged 60 to 69 years but with hypertension, diabetes and\u002For clinical proteinuria) will be allocated to perfusion with or without adsorption using a 1:1 randomization ratio. When both donor kidneys will have a score from 0 to 4, the two kidneys will be used for two single transplants. When one kidney will have a score from 0 to 4 and the other kidney will have a score of 5 or more, and when both kidneys will have a score from 5 to 7, the two kidneys will be transplanted together into the same recipient. If one kidney will have a score from 5 to 7 and the other kidney will have a score of 8 or greater, the two kidneys will be discarded. With the use of the minimization method, the randomization will be planned in order to have the same number of single or dual transplants in the perfusion kidney groups with or without adsorption. Donor selection, kidney evaluation and allocation and recipient management will be based on per center practice.",[30],[63,64,65],"Kidney perfusion","Absorption","Marginal donors","RECRUITING","2024-11-21",{"date":69,"type":40},"2024-11-22",{"date":71,"type":40},"2024-10-22",{"date":73,"type":22},"2026-05",{"name":75,"class":47},"Mario Negri Institute for Pharmacological Research",1]