[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"kidneys\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:kidneys":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100558752","cardio-and-renovascular-effects-of-isometric-exercise-in-the-healthy-human-measured-by-petct-and-mri-100558752",false,"NCT06555211","Cardio and Renovascular Effects of Isometric Exercise in the Healthy Human Measured by PET\u002FCT and MRI","Cardio and Renovascular Effects of Static Muscle Work in the Healthy Human - Measured With Finapres® and Positron Emission Tomography (PET) Using 15-oxygen Labeled Water as Tracer Compared to Magnetic Resonance (MR)","Inclusion Criteria:\n\n* Normal health stated through medical questionnaire, examination and blood samples.\n\nExclusion Criteria:\n\n* Immunosuppressive treatment\n* Alcohol abuse\n* Treatment with glucocorticoids, Glucagon-like peptide-1 (GLP-1) agonists, dipeptidyl peptidase 4 (DPP-4)-inhibitors\n* Medical treatment affecting insulin secretion or cardiovascular endpoints\n* Liver disease\n* Decreased kidney function\n* Severe claustrophobia\n* Elements incompatible with MR.",true,"MALE","18 Years","60 Years",{"count":21,"type":22},10,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized crossover study aims to validate measurements of renal perfusion in healthy males with PET\u002FCT, using 15-oxygen labeled water as tracer, against the validated multiparametric MRI technique.\n\nThe study will determine:\n\n* Total renal blood flow and regional renal perfusion at baseline (rest) and during isometric muscle exercise of the upper arm, using PET\u002FCT (with 15-oxygen labeled water as a tracer) and MRI.\n* The coefficient of variation of renal blood flow and regional renal perfusion measurements at baseline and during isometric muscle exercise of the upper arm, using PET\u002FCT (with 15-oxygen labeled water as a tracer) and MRI.\n* Regional renal oxygenation and oxygen extraction at baseline and during isometric muscle exercise of the upper arm using MRI.\n* The coefficient of variation on regional renal oxygenation and oxygen extraction measurements at baseline and during isometric muscle exercise of the upper arm using MRI.",[28],"Kidneys",[30,31,32,33],"Total renal blood flow","Regional renal perfusion","Regional renal oxygenation","Renal oxygen extraction","RECRUITING","2024-08-12",{"date":37,"type":38},"2024-08-15","ACTUAL",{"date":40,"type":38},"2024-05-07",{"date":42,"type":22},"2024-12",{"name":44,"class":45},"Bispebjerg Hospital","OTHER"]