[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"knee-replacement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:knee-replacement":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,73,101,125],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100575167","optimizing-a-remote-based-physical-activity-intervention-for-adults-with-total-knee-replacement-100575167",false,"NCT06768762","Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement","MOST Energized","Inclusion Criteria:\n\n* had a knee replacement (including primary, staged or independent bilateral, or revision) at least 12 months ago\n* have a computer, tablet, or smartphone with active internet access\n* self-report engaging in less than 60 minutes\u002Fweek of moderate-intensity physical activity\n* be English-speaking and able to read consent and study materials written in English\n* be willing to complete the 4 remote assessments, including physical activity monitoring\n* be willing to be randomized to receive 0-4 supplemental intervention components.\n\nExclusion Criteria:\n\n* any contraindications to physical activity (e.g., chest pain)\n* have a scheduled surgery within the next 12 months (e.g., hip or knee replacement)\n* have a mobility limiting comorbidity unrelated to knee replacement\n* live outside of the continental U.S\n* do not currently have a physician or orthopedic surgeon whom they see regularly\n* are currently participating in physical therapy (for knee)\n* are participating in a structured weight loss or physical activity program\n* unable to provide proof of knee replacement surgery\n* have a BMI \\>40kg\u002Fm2\n* score \\>30 on PROMIS cognitive function","ALL","18 Years",{"count":19,"type":20},336,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \\[≥150 min\u002Fweek of MVPA\\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.",[26],"Knee Replacement",[28,29,30],"knee replacement","exercise","online","RECRUITING","2026-04-28",{"date":34,"type":35},"2026-05-05","ACTUAL",{"date":37,"type":35},"2025-01-21",{"date":39,"type":20},"2029-07-31",{"name":41,"class":42},"University of South Carolina","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100590494","investigating-patient-satisfaction-with-smart-knee-implants-100590494","NCT06968143","Investigating Patient Satisfaction With Smart Knee Implants","Evaluating the Impact of Remote Therapeutic Monitoring on Knee Arthroplasty Recovery","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients undergoing unilateral primary or revision total knee arthroplasty with the smart knee implant or standard-of-care\n\nExclusion Criteria:\n\n* Patients who receive contralateral knee replacement or contralateral or unilateral hip replacement within 90 days before or after their knee replacement in this study\n* Patients with post-operative weight-bearing restrictions or physical deconditioning prohibiting routine physical therapy participation",true,{"count":53,"type":20},150,[23],"The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee replacement surgery, as tracked through remote monitoring. A secondary goal is to find out if patients' self-reported pain and function score are linked to their actual physical improvement after surgery as measured by a remote therapeutic monitoring (RTM) device. Additionally, this study examines whether RTM can reduce the number of postoperative clinic visits within the first 90 days after surgery while maintaining patient satisfaction and patient-reported outcome measures (PROMs).",[57,26,58,59],"Total Knee Arthroplasty","Knee Replacement Arthroplasty","Knee Osteoarthritis",[61,57,62,63],"Smart Knee Implant","Remote Therapeutic Monitoring","Persona IQ","2025-12-15",{"date":66,"type":35},"2025-12-17",{"date":68,"type":35},"2025-09-01",{"date":70,"type":20},"2027-10-31",{"name":72,"class":42},"University of Chicago",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":43},"100587849","effect-of-virtual-reality-on-patient-outcomes-and-satisfaction-in-total-knee-replacement-100587849","NCT06933732","Effect of Virtual Reality on Patient Outcomes and Satisfaction in Total Knee Replacement","The Effect of Virtual Reality Applications on Patient Outcomes and Satisfaction Before and After Total Knee Replacement: A Randomised Controlled Study","Inclusion Criteria:\n\n* Patients with an ASA score of 1, 2, or 3\n* Elective unilateral total knee replacement surgery was planned,\n* Patients who are able to read and write in Turkish\n\nExclusion Criteria:\n\n* Using \\>30 mg of oral oxycodone or equivalent daily\n* Long-term opioid use (\\>12 weeks)\n* Substance use disorder\n* Scheduled for emergency surgery\n* Scheduled for revision surgery\n* Requiring postoperative intensive care\n* Patients with visual or hearing impairments\n* Individuals experiencing motion-related nausea or dizziness\n* History of stroke or dementia\n* Pregnant or breastfeeding women\n* Patients with a history of epilepsy or seizures","65 Years",{"count":82,"type":20},64,[23],"This study aims to evaluate the effectiveness of virtual reality (VR) in managing preoperative anxiety and postoperative pain in patients undergoing total knee replacement. Investigators will assess the impact of preoperative VR training on anxiety levels, explore the effectiveness of relaxing and distracting VR videos for pain management after surgery, and determine the optimal timing for VR application by comparing different VR intervention times. Our goal is to identify how VR can improve both the emotional and physical recovery process for patients undergoing knee replacement surgery.",[26,86,87,88,89,90],"Knee Replacement Surgery","Postoperative Pain, Acute","Anxiety, Preoperative","Pain Management","Virtual Reality","NOT_YET_RECRUITING","2025-09-23",{"date":94,"type":35},"2025-09-26",{"date":96,"type":20},"2025-12-25",{"date":98,"type":20},"2026-03-31",{"name":100,"class":42},"Aykut Turgut",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":124},"100474595","the-medacta-gmk-spherika-post-marketing-surveillance-study-100474595","NCT05459948","The Medacta GMK SpheriKA Post-Marketing Surveillance Study","Medacta GMK® SpheriKA and Kinematic Alignment Technique Multicenter, Post-Market Outcome Study","Inclusion Criteria:\n\n* Patients willing to sign the informed consent.\n* Patients able to comply with follow-up requirements, including postoperative weight-bearing restrictions and self-evaluations.\n* Patients 18 - 80 years of age at the time of surgery.\n* Patients requiring a primary total knee replacement (on label use).\n* Patients with intact collateral ligaments.\n\nExclusion Criteria:\n\n* Patients with inflammatory arthritis.\n* Morbidly obese patients, with a body mass index (BMI) \\> 40.\n* Patients with a history of total or unicompartmental reconstruction of the affected joint.\n* Patients that have had a high tibial osteotomy or femoral osteotomy.\n* Patients with neuromuscular or neurosensory deficiency, which would limit the ability to assess the performance of the device.\n* Patients with a systemic or metabolic disorder leading to progressive bone deterioration.\n* Patients that are immunologically compromised or receiving chronic steroids (\\> 30 days).\n* Patients whose bone stock is compromised due to disease or infection, unable to provide adequate support and\u002For fixation to the prosthesis.\n* Patients with an active or suspected latent infection in or surrounding the knee joint.\n* Pregnant or breastfeeding women.","80 Years",{"count":110,"type":20},281,"OBSERVATIONAL","This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.",[114,26],"Arthropathy",{"date":116,"type":35},"2025-09-29",{"date":118,"type":35},"2022-07-30",{"date":120,"type":20},"2035-05",{"name":122,"class":123},"Medacta International SA","INDUSTRY",4,{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":51,"sex":16,"minAge":17,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":21,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":43},"100601366","the-effect-of-baduanjin-on-patients-undergoing-knee-replacement-surgery-100601366","NCT07109557","The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery","The Effect of Baduanjin on Pain, Comfort, and Quality of Recovery in Patients Undergoing Knee Replacement Surgery","Inclusion Criteria:\n\n* Having undergone Knee Replacement Surgery under general anesthesia\n\n  • 18 years old and over,\n* Are in stable condition after surgery,\n* Are conscious, and\n* Volunteer to participate in the study.\n\nExclusion Criteria:\n\n* Patients with contraindications to Baduanjin exercises,\n\n  -• Over 70 years old,\n\n  • Using anxiolytic and sedative drugs,\n* Patients with any mental illness and those who do not meet the inclusion criteria will not be included in the study.","70 Years",{"count":134,"type":20},60,[23],"This randomized controlled trial aims to evaluate the effects of Baduanjin, a traditional Chinese mind-body exercise, on pain, comfort, and quality of recovery in patients undergoing total knee arthroplasty (TKA). The study will be conducted between July 2025 and July 2026 at Yalova Training and Research Hospital's Orthopedics Clinic. Sixty patients will be randomly assigned into two groups: an intervention group practicing Baduanjin and a control group receiving standard postoperative care. The intervention will begin on the first postoperative day and continue for three weeks. Outcome measures include the Visual Analog Scale (VAS) for pain, the General Comfort Questionnaire, and the Quality of Recovery-40 (QoR-40) questionnaire. These assessments will be conducted weekly for three weeks. The control group will follow routine postoperative care without Baduanjin. The primary objective is to determine whether Baduanjin can improve postoperative outcomes in terms of pain reduction, increased comfort, and better recovery quality.",[138,139,26,140],"Pain, Postoperative","Surgery","Nurse's Role","2025-08-07",{"date":143,"type":35},"2025-08-12",{"date":145,"type":35},"2025-07-01",{"date":147,"type":20},"2026-12-01",{"name":149,"class":42},"Niran Çoban"]