[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"knee-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:knee-surgery":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,73,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100640500","comparison-of-analgesic-efficacy-and-impact-on-motor-function-in-knee-replacement-surgery-01-naropeine-tri-block-versus-05-naropeine-ipack-saphenous-block---a-prospective-randomised-trial-100640500",false,"NCT07578688","Comparison of Analgesic Efficacy and Impact on Motor Function in Knee Replacement Surgery: 0.1% Naropeine Tri-block Versus 0.5% Naropeine iPACK Saphenous Block - A Prospective Randomised Trial","ProBlocs","Inclusion Criteria:\n\n* Age \\> 18 years;\n* Patients scheduled for total knee replacement (TKR);\n* ASA (American Society of Anesthesiologists) class 1 to 3;\n* Patient who is able to understand the information relating to the study, read the information leaflet and agree to sign the informed consent form;\n* Enrolment iin the French healthcare system.\n\nExclusion Criteria:\n\n* Patients with an ASA score \\> 3;\n* Patients with a chronic pain condition requiring regular prescription pain relief, such as osteoarthritis, fibromyalgia, neuropathic pain or rheumatoid arthritis;\n* Patients with a major anxiety disorder (APAIS score);\n* Patients with a history of algodystrophy;\n* Pregnant or breastfeeding women;\n* History or evidence of any other clinically significant disorder, condition or disease which, in the investigator's opinion, would pose a risk to patient safety or interfere with the assessment, procedures or completion of the study;\n* Participation in any other clinical trial during the duration of the study;\n* Patients under guardianship or curatorship or subject to deprivation of liberty.","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","Over the last two decades, perioperative analgesia has evolved. Spinal and epidural anaesthesia, once common, have been gradually phased out due to their side effects. The femoral block combined with the sciatic block, possibly with a perineural catheter, is now the gold standard for ensuring prolonged, high-quality analgesia. However, these blocks can cause muscle weakness in the quadriceps, limiting patients' functional recovery.\n\nTo optimise functional rehabilitation, recent techniques favour more distal and selective blocks, such as the adductor canal (saphenous) block and the iPACK, which allow effective anaesthesia to be maintained whilst preserving motor function. However, these blocks do not always guarantee complete analgesia and may require additional blocks.\n\nThe hypothesis of the current study is based on the idea that a proximal block targeting the femoral, obturator and sciatic nerves, administered with a low concentration of naropeine (0.1%), could provide more effective analgesia than a 0.5% saphenous iPACK block, whilst preserving motor function The originality of our approach in the current study lies in the use of dissociative proximal blocks performed with low concentrations of local anaesthetics, aimed at effectively covering the innervation of the knee whilst preserving motor function.\n\nThe expected outcomes of this research are to optimise analgesic management for patients undergoing functional orthopaedic knee surgery, to promote early postoperative walking rehabilitation, to reduce the risk of chronic pain following knee arthroplasty, and to provide evidence to guide anaesthetic and post-surgical rehabilitation practices",[26],"Knee Surgery","NOT_YET_RECRUITING","2026-05-05",{"date":30,"type":31},"2026-05-11","ACTUAL",{"date":33,"type":20},"2026-09-30",{"date":35,"type":20},"2027-12-31",{"name":37,"class":38},"GCS Ramsay Santé pour l'Enseignement et la Recherche","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":39},"100633740","effects-of-music-listening-and-relaxation-interventions-on-postoperative-recovery-after-knee-surgery-100633740","NCT07530614","Effects of Music Listening and Relaxation Interventions on Postoperative Recovery After Knee Surgery","Effects of Music Listening and Emotional Freedom Techniques on Fall Risk, Kinesiophobia, and Pain Following Knee Arthroscopy","EFT","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Scheduled for elective knee arthroscopy\n* Anxiety-fear intensity score ≥2 on the Subjective Units of Distress (SUD) scale\n* No hearing or speech problems that would prevent communication\n* No cognitive or mental impairments\n* No psychiatric disorders\n* No pain, tenderness, or wounds at the meridian points where Emotional Freedom Techniques (EFT) will be applied\n* Have not received prior training in coping with anxiety or fear\n* Have not previously attended courses related to energy therapy\n* Agree to participate in the study\n\nExclusion Criteria:\n\n* Currently using psychiatric medications\n* Receiving active psychological therapy\n* Experiencing postoperative surgical complications\n* Having traumatic lower extremity fractures\n* Undergoing simultaneous bilateral knee arthroscopy","65 Years",{"count":50,"type":20},85,[23],"This study aims to evaluate whether listening to music and using Emotional Freedom Techniques (EFT) can help patients recover better after knee arthroscopy. After this type of surgery, many patients experience pain, fear of movement (kinesiophobia), balance problems, and an increased risk of falling.\n\nIn this study, patients will receive music listening and EFT as supportive, non-drug interventions during the postoperative period. The goal is to determine whether these simple and safe methods can reduce pain, decrease fear of movement, and lower fall risk, ultimately improving recovery.\n\nThe findings of this study may help healthcare professionals, especially nurses, provide more holistic and patient-centered care after knee surgery.",[26,54,55,56],"Kinesiophobia (Fear of Movement)","Postoperative Pain","Arthroscopic Surgery",[58,59,60,61,62,63],"Emotional Freedom Techniques","knee surgery","arthroscopy","listening to music","kinesiophobia","postoperative pain","2026-04-10",{"date":66,"type":31},"2026-04-15",{"date":68,"type":20},"2026-03-30",{"date":70,"type":20},"2027-01-28",{"name":72,"class":38},"Arzum ÇELİK BEKLEVİÇ",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":97,"leadSponsor":99,"locationsCount":39},"100610915","comparison-of-acb-with-acb-and-bifes-combination-in-knee-arthroplasty-surgeries-100610915","NCT07233785","Comparison of ACB With ACB and BiFeS Combination in Knee Arthroplasty Surgeries","Comparison of the Postoperative Analgesic Efficacy of the Combination of Adductor Canal Block and Biceps Femoris Short Head Block Versus Adductor Canal Block Alone in Patients Undergoing Total Knee Arthroplasty","Inclusion Criteria:\n\n* Adult patients over 18 years of age who underwent percutaneous nephrolithotomy under general anesthesia and were I-II-III according to the American Society of Anesthesiologists (ASA) risk classification were included in the study.\n\nExclusion Criteria:\n\n* patients who did not give consent,\n* patients with coagulopathy,\n* patients with signs of infection at the block application site,\n* patients using anticoagulants,\n* patients with known allergies to any of the study drugs,\n* patients with unstable hemodynamics,\n* patients who could not cooperate during postoperative pain assessment\n* patients who wanted to withdraw from the study,\n* patients with alcohol and drug addiction,\n* patients with musculoskeletal abnormalitie",{"count":81,"type":20},60,[23],"The aim is to compare the postoperative analgesic effects of Adductor Canal and Biceps Femoris Short Head Blocks with Adductor Canal Block in patients undergoing Knee Arthroplasty surgery",[85,26,86],"Postoperative Pain Management","Knee Arthroplasty, Total",[63,88,89,90,91,92],"knee arthroplasty","biceps femoris short head","bifes","adductor canal blok","regional anesthesia","2025-11-20",{"date":95,"type":31},"2025-11-25",{"date":93,"type":20},{"date":98,"type":20},"2026-11-25",{"name":100,"class":38},"Cumhuriyet University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":123},"100532066","fh-ortho-sas-knee-observatory-100532066","NCT06207968","FH ORTHO SAS Knee Observatory","Post Market Clinical Follow-up of Knee Surgery Using FH ORTHO SAS Medical Devices (FH ORTHO SAS Knee Observatory)","Inclusion Criteria:\n\n* Any patient undergoing or having undergone implantation of medical devices distributed by FH ORTHO SAS for knee arthroplasty and ligament reconstruction, used in accordance with their approved IFU, in one of the centers participating in the Observatory.\n* Patient is at least 18 years old at the time of surgery\n* Patient agreeing to participate after having been informed orally and in writing (with written consent if required locally)\n* In some countries, such as France, the patient will have to be socially insured to be included in the study.\n\nExclusion Criteria:\n\nFor Arthroplasty:\n\n1. Infection, or latent infection\n2. A mental or neuromuscular disorder that might create an unacceptable risk of instability, prosthetic fixation failure, or complications after surgery\n3. Insufficient bone stock for proper implant fixation\n4. It is the surgeon's responsibility to make sure that the patient does not have any known allergies to one of the compounds of the material listed on the product label.\n5. Metabolic diseases that might compromise bone regrowth\n6. Drug addiction\n7. Incomplete bone growth\n\nFor Ligament reconstruction:\n\n1. Infection, or latent infection\n2. A mental or neuromuscular disorder that might create an unacceptable risk of instability, prosthetic fixation failure, or complications after surgery\n3. Insufficient bone stock\n4. Known allergies to one of the compounds of the material listed on the product label.\n5. Metabolic diseases that might compromise bone regrowth\n6. Uncooperative patient unable to follow recommendations\n\nAs the medical devices are used in real life according to their indications, pregnant or breastfeeding women are not excluded from the study, but for safety reasons it is not advisable to include them in the study.",{"count":109,"type":20},487,"OBSERVATIONAL","The objective of this observatory is to generate additional real life clinical data in accordance with local regulation (i.e. Post-Market Clinical Follow-up (PMCF) study, a study carried out following the European Conformity (CE) marking of a device and intended to answer specific questions relating to clinical safety or performance (i.e. residual risks) of a device when used in accordance with its approved instructions for use (IFU).\n\nThe difficulty of such an observatory is to be able to collect data on the different versions of the devices, on the different possible combinations of implants of an knee arthroplasty. The observatory must also be able to cover devices used in ligament reconstruction surgery.\n\nThe observatory will be based on the principle of a \"dynamic\" cohort during the inclusion period, i.e. with possible inclusions to replace the premature exits.\n\nTechnical solutions will be implemented to facilitate data collection from surgeons (electronic Case Report Form (eCRF) and from patients (Electronic Patient Reported Outcome (ePRO) on smartphone\u002Ftablet\u002Fcomputer) when feasible.\n\nThe data to be collected and the different follow-up times are based on our state-of-the-art, clinical evaluation plans and clinical evaluation reports.",[26],"2024-02-21",{"date":115,"type":31},"2024-02-22",{"date":117,"type":20},"2024-05",{"date":119,"type":20},"2044-06",{"name":121,"class":122},"FH ORTHO","INDUSTRY",10]