[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"knee-swelling-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:knee-swelling-pain":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100630989","images-identifying-metabolic-imaging-association-with-genicular-artery-embolization-success-100630989",false,"NCT07494838","IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success","Inclusion Criteria:\n\n* Provided informed consent\n* Age ≥ 40 years\n* Ineligibility for or refusal of surgical management\n* Moderate-severe knee pain as determined by visual analog scale \\> 5 out of 10\n* Osteoarthritis based on X-ray. Kellgren-Lawrence score \\> 2 based on radiograph completed within 3 months of procedure date\n* Resistant\u002Ffailed some form of conservative treatment (e.g. NSAIDS\u002Fphysical therapy\u002Fsteroid joint injection\u002Fhyaluronic acid joint injection) for at least 3 months\n* Able to comply with all treatments and protocol follow-up visits\n\nExclusion Criteria:\n\n* Mild knee pain as determined by visual analog scale \\\u003C 5 out of 10\n* OA on knee radiograph resulting in greater than 20 degree varus or valgus angulation\n* Moderate loss of kidney function, define as estimated glomerular filtration rate of less than 45 mL\u002Fmin.\n* Significant arterial atherosclerosis that would limit selective angiography\n* History of fibromyalgia, autoimmune, or inflammatory disorder\n* History of any lumbar spine surgery, spine injections, or radicular pain in the extremity believed to originate from the spine\n* Allergy to iodinated contrast agents\n* Active infection or malignancy\n* Recent (within 12 months) or active cigarette use\n* Prior total or partial knee replacement in the subject knee\n* Active pregnancy\n* Uncorrectable bleeding diathesis\n* Presence of pacemakers, aneurysm clips, neurostimulators, or any other metal implant not compatible with PET\u002FMRI","ALL","40 Years",{"count":18,"type":19},25,"ESTIMATED","INTERVENTIONAL",[22],"NA","Several clinical trials on genicular artery embolization (GAE) show significant clinical benefit for the majority of patients. However, a proportion of patients do not benefit from GAE, and responses vary across individual patients. Changes in metabolic activity on non-invasive imaging may correlate with improvement in symptoms of knee osteoarthritis. This study will assess changes in metabolic uptake on a hybrid positron emission tomography\u002Fmagnetic resonance imaging (PET\u002FMRI) system in subjects undergoing GAE.",[25,26,27,28],"Knee Osteoarthritis","Knee Discomfort","Knee Pain Chronic","Knee Swelling Pain",[30],"GAE","NOT_YET_RECRUITING","2026-03-21",{"date":34,"type":35},"2026-03-27","ACTUAL",{"date":37,"type":19},"2026-06-30",{"date":39,"type":19},"2027-06-30",{"name":41,"class":42},"Lucas R. Cusumano, MD","OTHER"]